Rat bone marrow stromal cells express retinal phenotypic markers following different induction rotocols

Ophthalmic Research

Volumn 41, Issue 4, 2009, Pages 186-193

  Liu, Dong Ning ^a   Yin, Zheng Qin ^a   Wu, Nan ^a   Wang, Yan Hua ^a   Chen, Li Feng ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Bone marrow stromal cell differentiation; Cytokine basic fibroblast growth factor; Postnatal retinal cell co cultures

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2; OPSIN; PROTEIN KINASE C ALPHA; THY 1 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMUR; IMMUNOCYTOCHEMISTRY; MORPHOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA GANGLION CELL; RETINA NERVE CELL;

ANIMALS; ANTIGENS, THY-1; BIOLOGICAL MARKERS; BONE MARROW CELLS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; FIBROBLAST GROWTH FACTOR 2; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE-ASSOCIATED PROTEINS; OPSINS; PROTEIN KINASE C-ALPHA; RATS; RETINAL NEURONS; STROMAL CELLS;

EID: 65649137812     PISSN: 00303747     EISSN: None     Source Type: Journal    
DOI: 10.1159/000217722     Document Type: Article

References (23)

1. Lund RD, Kwan ASL, Keegan DJ, Sauve Y, Coffey PJ, Lawrence JM: Cell transplantation as a treatment for retinal disease. Prog Retin Eye Res 2001;20:415 - 449.
2. Levin LA, Ritch R, Richards JE, Borras T: Stem cell therapy for ocular disorders. Arch Opthalmol 2004;122:621-627.
3. Kicic A, Shen WY, Wilson AS, Constable IJ, Robertson T, Rakoczy PE: Differentiation of marrow stromal cells into photoreceptors in the rat eye. J Neurosci 2003;23:7742-7749.
4. Jiang Y, Jahagidar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund T, Blackstad M, Du J, Aldrich S, Lisberg A, Low WC, Largaespada DA, Verfaillie CM: Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002;418:41-49.
5. Pittenger MF, Martin BJ: Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res 2004;95:9-20.
6. Black IB, Woodbury D: Adult rat and human bone marrow stromal stem cells differentiate into neurons. Blood Cells Mol Dis 2001;27:632-636.
7. Rismanchi N, Floyd CL, Berman RF, Lyeth BG: Cell death and long-term maintenance of neuron-like state after differentiation of rat bone marrow stromal cells: a comparison of protocols. Brain Res 2003;991:46-55.
8. Yaghoobi MM, Mowla SJ: Differential gene expression pattern of neurotrophins and their receptors during neuronal differentiation of rat bone marrow stromal cells. Neurosci Let t 2006;397:149-154.
9. Deng W, Obrocka M, Fischer I, Prockop DJ: In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochem Biophys Res Commun 2001;282:148-152.
10. Yamaguchi S, Kuroda S, Kobayashi H, Shichinohe H, Yano S, Hida K, Shinpo K, Kikuchi S, Iwasaki Y: The effects of neuronal induction on gene expression profile in bone marrow stromal cells (BMSCs) - a preliminary study using microarray analysis. Brain Res 2006;1087:15-27.
11. Abouelfetouh A, Kondoh T, Ehara K, Kohmura E: Morphological differentiation of bone marrow stromal cells into neuron-like cells after co-culture with hippocampal slice. Brain Res 2004;1029:114-119.
12. Keirstead HS: Stem cells for the treatment of myelin loss. Trends Neurosci 2005;28:677-683.
13. Chiou SH, Kao CL, Peng CH, Chen SJ, Tarng YW, Ku HH, Chen YC, Shyr YM, Liu RS, Hsu CJ, Yang DM, Hsu WM, Kuo CD, Lee CH: A novel in vitro retinal differentiation model by co-culturing adult human bone marrow stem cells with retinal pigmented epithelium cells. Biochem Biophys Res Commun 2005;326:578-585.
14. Fuchs E, Tumbar T, Guasch G: Socializing with the neighbours: stem cells and their niche. Cell 2004;116:769-778.
15. Spradling A, Drummond-Barbosa D, Kai T: Stem cells find their niche. Nature 2001;414:98-104.
16. Song HJ, Stevens CF, Gage FH: Astroglia induce neurogenesis from adult neural stem cells. Nature 2002;417:39-44.
17. 3H; in Smelser GK (ed): The Structure of the Eye. New York, Academic Press, 1961, pp 487-505.
18. Bossolasco P, Cova L, Calzarossa C, Rimoldi SG, Borsotti C, Lambertenghi Deliliers G, Silani V, Soligo D, Polli E: Neuro-glial differentiation of human bone marrow stem cells in vitro. Exp Neurol 2005;193:312-325.
19. Song HJ, Stevens CF, Gage FH: Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons. Nat Neurosci 2002;5:438-445.
20. Tomita M, Mori T, Maruyama K, Zahir T, Ward M, Umezawa A, Young MJ: A comparison of neural differentiation and retinal transplantation with bone marrow-derived cells and retinal progenitor cells. Stem Cells 2006;24:2270-2278.
21. Arnhold S, Heiduschka P, Klein H, Absenger Y, Basnaoglu S, Kreppel F, Henke-Fahle S, Kochanek S, Bartz-Schmidt KU, Addicks K, Schaermeyer U: Adenovirally transduced bone marrow stromal cells differentiate into pigment epithelial cells and induce rescue effects in RCS rats. Invest Ophthal Vis Sci 2006;47:4121-4129.
22. Klassen H, Sakaguchi DS, Young MJ: Stem cells and retinal repair. Prog Retin Eye Res 2004;23:149-181.
23. Connolly SE, Hjelmeland LM, LaVail MM: Immunohistochemical localization of basic fibroblast growth factor in mature and developing retinas of normal and RCS rats. Curr Eye Res 1992;11:1005-1017.