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Volumn 15, Issue 6, 2009, Pages 465-476

Genetic p53 Deficiency Partially Rescues the Adrenocortical Dysplasia Phenotype at the Expense of Increased Tumorigenesis

Author keywords

CELLCYCLE

Indexed keywords

PROTEIN P53;

EID: 65649133036     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2009.04.011     Document Type: Article
Times cited : (53)

References (63)
  • 2
    • 0036137878 scopus 로고    scopus 로고
    • Telomere shortening and cell fates in mouse models of neoplasia
    • Artandi S.E. Telomere shortening and cell fates in mouse models of neoplasia. Trends Mol. Med. 8 (2002) 44-47
    • (2002) Trends Mol. Med. , vol.8 , pp. 44-47
    • Artandi, S.E.1
  • 3
    • 0034003333 scopus 로고    scopus 로고
    • A critical role for telomeres in suppressing and facilitating carcinogenesis
    • Artandi S.E., and DePinho R.A. A critical role for telomeres in suppressing and facilitating carcinogenesis. Curr. Opin. Genet. Dev. 10 (2000) 39-46
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 39-46
    • Artandi, S.E.1    DePinho, R.A.2
  • 4
    • 0034632717 scopus 로고    scopus 로고
    • Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice
    • Artandi S.E., Chang S., Lee S.L., Alson S., Gottlieb G.J., Chin L., and DePinho R.A. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice. Nature 406 (2000) 641-645
    • (2000) Nature , vol.406 , pp. 641-645
    • Artandi, S.E.1    Chang, S.2    Lee, S.L.3    Alson, S.4    Gottlieb, G.J.5    Chin, L.6    DePinho, R.A.7
  • 5
    • 34447500134 scopus 로고    scopus 로고
    • Oligonucleotide treatment increases eumelanogenesis, hair pigmentation and melanocortin-1 receptor expression in the hair follicle
    • Atoyan R.Y., Sharov A.A., Eller M.S., Sargsyan A., Botchkarev V.A., and Gilchrest B.A. Oligonucleotide treatment increases eumelanogenesis, hair pigmentation and melanocortin-1 receptor expression in the hair follicle. Exp. Dermatol. 16 (2007) 671-677
    • (2007) Exp. Dermatol. , vol.16 , pp. 671-677
    • Atoyan, R.Y.1    Sharov, A.A.2    Eller, M.S.3    Sargsyan, A.4    Botchkarev, V.A.5    Gilchrest, B.A.6
  • 7
    • 22944488871 scopus 로고    scopus 로고
    • Telomeres and human disease: ageing, cancer and beyond
    • Blasco M.A. Telomeres and human disease: ageing, cancer and beyond. Nat. Rev. Genet. 6 (2005) 611-622
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 611-622
    • Blasco, M.A.1
  • 9
    • 22144490491 scopus 로고    scopus 로고
    • DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
    • Celli G.B., and de Lange T. DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion. Nat. Cell Biol. 7 (2005) 712-718
    • (2005) Nat. Cell Biol. , vol.7 , pp. 712-718
    • Celli, G.B.1    de Lange, T.2
  • 10
    • 3242709415 scopus 로고    scopus 로고
    • Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway
    • Chiang Y.J., Kim S.H., Tessarollo L., Campisi J., and Hodes R.J. Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway. Mol. Cell. Biol. 24 (2004) 6631-6634
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 6631-6634
    • Chiang, Y.J.1    Kim, S.H.2    Tessarollo, L.3    Campisi, J.4    Hodes, R.J.5
  • 13
    • 0033553516 scopus 로고    scopus 로고
    • p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
    • Chin L., Artandi S.E., Shen Q., Tam A., Lee S.L., Gottlieb G.J., Greider C.W., and DePinho R.A. p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 97 (1999) 527-538
    • (1999) Cell , vol.97 , pp. 527-538
    • Chin, L.1    Artandi, S.E.2    Shen, Q.3    Tam, A.4    Lee, S.L.5    Gottlieb, G.J.6    Greider, C.W.7    DePinho, R.A.8
  • 15
    • 34247860915 scopus 로고    scopus 로고
    • Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence
    • Cosme-Blanco W., Shen M.F., Lazar A.J., Pathak S., Lozano G., Multani A.S., and Chang S. Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence. EMBO Rep. 8 (2007) 497-503
    • (2007) EMBO Rep. , vol.8 , pp. 497-503
    • Cosme-Blanco, W.1    Shen, M.F.2    Lazar, A.J.3    Pathak, S.4    Lozano, G.5    Multani, A.S.6    Chang, S.7
  • 17
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: the protein complex that shapes and safeguards human telomeres
    • de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 19 (2005) 2100-2110
    • (2005) Genes Dev. , vol.19 , pp. 2100-2110
    • de Lange, T.1
  • 19
    • 27844572373 scopus 로고    scopus 로고
    • Genetic analysis of adrenal absence: agenesis and aplasia
    • Else T., and Hammer G.D. Genetic analysis of adrenal absence: agenesis and aplasia. Trends Endocrinol. Metab. 16 (2005) 458-468
    • (2005) Trends Endocrinol. Metab. , vol.16 , pp. 458-468
    • Else, T.1    Hammer, G.D.2
  • 21
    • 42049093996 scopus 로고    scopus 로고
    • Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma
    • Else T., Giordano T.J., and Hammer G.D. Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma. J. Clin. Endocrinol. Metab. 93 (2008) 1442-1449
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 1442-1449
    • Else, T.1    Giordano, T.J.2    Hammer, G.D.3
  • 22
    • 0028223562 scopus 로고
    • Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice
    • Enders G.C., and May II J.J. Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice. Dev. Biol. 163 (1994) 331-340
    • (1994) Dev. Biol. , vol.163 , pp. 331-340
    • Enders, G.C.1    May II, J.J.2
  • 23
    • 0042440603 scopus 로고    scopus 로고
    • Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma
    • Farazi P.A., Glickman J., Jiang S., Yu A., Rudolph K.L., and DePinho R.A. Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma. Cancer Res. 63 (2003) 5021-5027
    • (2003) Cancer Res. , vol.63 , pp. 5021-5027
    • Farazi, P.A.1    Glickman, J.2    Jiang, S.3    Yu, A.4    Rudolph, K.L.5    DePinho, R.A.6
  • 24
    • 33845629456 scopus 로고    scopus 로고
    • A new paradigm for profiling testicular gene expression during normal and disturbed human spermatogenesis
    • Feig C., Kirchhoff C., Ivell R., Naether O., Schulze W., and Spiess A.N. A new paradigm for profiling testicular gene expression during normal and disturbed human spermatogenesis. Mol. Hum. Reprod. 13 (2007) 33-43
    • (2007) Mol. Hum. Reprod. , vol.13 , pp. 33-43
    • Feig, C.1    Kirchhoff, C.2    Ivell, R.3    Naether, O.4    Schulze, W.5    Spiess, A.N.6
  • 25
    • 0029894237 scopus 로고    scopus 로고
    • Telomere length regulation
    • Greider C.W. Telomere length regulation. Annu. Rev. Biochem. 65 (1996) 337-365
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 337-365
    • Greider, C.W.1
  • 26
    • 36248952723 scopus 로고    scopus 로고
    • Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis
    • Guo X., Deng Y., Lin Y., Cosme-Blanco W., Chan S., He H., Yuan G., Brown E.J., and Chang S. Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis. EMBO J. 26 (2007) 4709-4719
    • (2007) EMBO J. , vol.26 , pp. 4709-4719
    • Guo, X.1    Deng, Y.2    Lin, Y.3    Cosme-Blanco, W.4    Chan, S.5    He, H.6    Yuan, G.7    Brown, E.J.8    Chang, S.9
  • 27
    • 41049115180 scopus 로고    scopus 로고
    • T-oligos as differential modulators of human scalp hair growth and pigmentation: a new "time lapse system" for studying human skin and hair follicle biology in vitro?
    • Hadshiew I., Barre K., Bodo E., Funk W., and Paus R. T-oligos as differential modulators of human scalp hair growth and pigmentation: a new "time lapse system" for studying human skin and hair follicle biology in vitro?. Arch. Dermatol. Res. 300 (2008) 155-159
    • (2008) Arch. Dermatol. Res. , vol.300 , pp. 155-159
    • Hadshiew, I.1    Barre, K.2    Bodo, E.3    Funk, W.4    Paus, R.5
  • 28
    • 0033593814 scopus 로고    scopus 로고
    • Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice
    • Hande M.P., Samper E., Lansdorp P., and Blasco M.A. Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice. J. Cell Biol. 144 (1999) 589-601
    • (1999) J. Cell Biol. , vol.144 , pp. 589-601
    • Hande, M.P.1    Samper, E.2    Lansdorp, P.3    Blasco, M.A.4
  • 29
    • 0034669532 scopus 로고    scopus 로고
    • Wild-derived inbred mouse strains have short telomeres
    • Hemann M.T., and Greider C.W. Wild-derived inbred mouse strains have short telomeres. Nucleic Acids Res. 28 (2000) 4474-4478
    • (2000) Nucleic Acids Res. , vol.28 , pp. 4474-4478
    • Hemann, M.T.1    Greider, C.W.2
  • 31
    • 33745685066 scopus 로고    scopus 로고
    • Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres
    • Hockemeyer D., Daniels J.P., Takai H., and de Lange T. Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell 126 (2006) 63-77
    • (2006) Cell , vol.126 , pp. 63-77
    • Hockemeyer, D.1    Daniels, J.P.2    Takai, H.3    de Lange, T.4
  • 33
    • 4544258775 scopus 로고    scopus 로고
    • A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2
    • Houghtaling B.R., Cuttonaro L., Chang W., and Smith S. A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2. Curr. Biol. 14 (2004) 1621-1631
    • (2004) Curr. Biol. , vol.14 , pp. 1621-1631
    • Houghtaling, B.R.1    Cuttonaro, L.2    Chang, W.3    Smith, S.4
  • 35
    • 11144268164 scopus 로고    scopus 로고
    • Significant role for p16INK4a in p53-independent telomere-directed senescence
    • Jacobs J.J., and de Lange T. Significant role for p16INK4a in p53-independent telomere-directed senescence. Curr. Biol. 14 (2004) 2302-2308
    • (2004) Curr. Biol. , vol.14 , pp. 2302-2308
    • Jacobs, J.J.1    de Lange, T.2
  • 36
    • 33744535197 scopus 로고    scopus 로고
    • Telomeres and telomerase in cancer stem cells
    • Ju Z., and Rudolph K.L. Telomeres and telomerase in cancer stem cells. Eur. J. Cancer 42 (2006) 1197-1203
    • (2006) Eur. J. Cancer , vol.42 , pp. 1197-1203
    • Ju, Z.1    Rudolph, K.L.2
  • 38
    • 12344282699 scopus 로고    scopus 로고
    • Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator
    • Keegan C.E., Hutz J.E., Else T., Adamska M., Shah S.P., Kent A.E., Howes J.M., Beamer W.G., and Hammer G.D. Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. Hum. Mol. Genet. 14 (2005) 113-123
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 113-123
    • Keegan, C.E.1    Hutz, J.E.2    Else, T.3    Adamska, M.4    Shah, S.P.5    Kent, A.E.6    Howes, J.M.7    Beamer, W.G.8    Hammer, G.D.9
  • 40
    • 40749104852 scopus 로고    scopus 로고
    • An extended transcriptional network for pluripotency of embryonic stem cells
    • Kim J., Chu J., Shen X., Wang J., and Orkin S.H. An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132 (2008) 1049-1061
    • (2008) Cell , vol.132 , pp. 1049-1061
    • Kim, J.1    Chu, J.2    Shen, X.3    Wang, J.4    Orkin, S.H.5
  • 44
    • 0029014274 scopus 로고
    • A cell-specific nuclear receptor plays essential roles in adrenal and gonadal development
    • Luo X., Ikeda Y., Lala D.S., Baity L.A., Meade J.C., and Parker K.L. A cell-specific nuclear receptor plays essential roles in adrenal and gonadal development. Endocr. Res. 21 (1995) 517-524
    • (1995) Endocr. Res. , vol.21 , pp. 517-524
    • Luo, X.1    Ikeda, Y.2    Lala, D.S.3    Baity, L.A.4    Meade, J.C.5    Parker, K.L.6
  • 45
    • 0037178761 scopus 로고    scopus 로고
    • Connecting chromosomes, crisis, and cancer
    • Maser R.S., and DePinho R.A. Connecting chromosomes, crisis, and cancer. Science 297 (2002) 565-569
    • (2002) Science , vol.297 , pp. 565-569
    • Maser, R.S.1    DePinho, R.A.2
  • 46
    • 0036102606 scopus 로고    scopus 로고
    • Telomere length assessment in human archival tissues: combined telomere fluorescence in situ hybridization and immunostaining
    • Meeker A.K., Gage W.R., Hicks J.L., Simon I., Coffman J.R., Platz E.A., March G.E., and De Marzo A.M. Telomere length assessment in human archival tissues: combined telomere fluorescence in situ hybridization and immunostaining. Am. J. Pathol. 160 (2002) 1259-1268
    • (2002) Am. J. Pathol. , vol.160 , pp. 1259-1268
    • Meeker, A.K.1    Gage, W.R.2    Hicks, J.L.3    Simon, I.4    Coffman, J.R.5    Platz, E.A.6    March, G.E.7    De Marzo, A.M.8
  • 49
    • 33747051742 scopus 로고    scopus 로고
    • A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly
    • O'Connor M.S., Safari A., Xin H., Liu D., and Songyang Z. A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly. Proc. Natl. Acad. Sci. USA 103 (2006) 11874-11879
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 11874-11879
    • O'Connor, M.S.1    Safari, A.2    Xin, H.3    Liu, D.4    Songyang, Z.5
  • 53
    • 0034978564 scopus 로고    scopus 로고
    • Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
    • Rudolph K.L., Millard M., Bosenberg M.W., and DePinho R.A. Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat. Genet. 28 (2001) 155-159
    • (2001) Nat. Genet. , vol.28 , pp. 155-159
    • Rudolph, K.L.1    Millard, M.2    Bosenberg, M.W.3    DePinho, R.A.4
  • 55
    • 0036170471 scopus 로고    scopus 로고
    • Quantification of telomerase activity, porphobilinogen deaminase and human telomerase reverse transcriptase mRNA in testicular tissue-new parameters for a molecular diagnostic classification of spermatogenesis disorders
    • Schrader M., Muller M., Schulze W., Heicappell R., Krause H., Straub B., and Miller K. Quantification of telomerase activity, porphobilinogen deaminase and human telomerase reverse transcriptase mRNA in testicular tissue-new parameters for a molecular diagnostic classification of spermatogenesis disorders. Int. J. Androl. 25 (2002) 34-44
    • (2002) Int. J. Androl. , vol.25 , pp. 34-44
    • Schrader, M.1    Muller, M.2    Schulze, W.3    Heicappell, R.4    Krause, H.5    Straub, B.6    Miller, K.7
  • 56
    • 0037102234 scopus 로고    scopus 로고
    • Different telomere damage signaling pathways in human and mouse cells
    • Smogorzewska A., and de Lange T. Different telomere damage signaling pathways in human and mouse cells. EMBO J. 21 (2002) 4338-4348
    • (2002) EMBO J. , vol.21 , pp. 4338-4348
    • Smogorzewska, A.1    de Lange, T.2
  • 57
    • 33847691863 scopus 로고    scopus 로고
    • Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome
    • Tabori U., Nanda S., Druker H., Lees J., and Malkin D. Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome. Cancer Res. 67 (2007) 1415-1418
    • (2007) Cancer Res. , vol.67 , pp. 1415-1418
    • Tabori, U.1    Nanda, S.2    Druker, H.3    Lees, J.4    Malkin, D.5
  • 58
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel B., Smogorzewska A., and de Lange T. TRF2 protects human telomeres from end-to-end fusions. Cell 92 (1998) 401-413
    • (1998) Cell , vol.92 , pp. 401-413
    • van Steensel, B.1    Smogorzewska, A.2    de Lange, T.3
  • 59
    • 47249142457 scopus 로고    scopus 로고
    • Splenic marginal zone lymphomas are characterized by loss of interstitial regions of chromosome 7q, 7q31.32 and 7q36.2 that include the protection of telomere 1 (POT1) and sonic hedgehog (SHH) genes
    • Vega F., Cho-Vega J.H., Lennon P.A., Luthra M.G., Bailey J., Breeden M., Jones D., Medeiros L.J., and Luthra R. Splenic marginal zone lymphomas are characterized by loss of interstitial regions of chromosome 7q, 7q31.32 and 7q36.2 that include the protection of telomere 1 (POT1) and sonic hedgehog (SHH) genes. Br. J. Haematol. 142 (2008) 216-226
    • (2008) Br. J. Haematol. , vol.142 , pp. 216-226
    • Vega, F.1    Cho-Vega, J.H.2    Lennon, P.A.3    Luthra, M.G.4    Bailey, J.5    Breeden, M.6    Jones, D.7    Medeiros, L.J.8    Luthra, R.9
  • 61
    • 33846692105 scopus 로고    scopus 로고
    • TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase
    • Xin H., Liu D., Wan M., Safari A., Kim H., Sun W., O'Connor M.S., and Songyang Z. TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase. Nature 445 (2007) 559-562
    • (2007) Nature , vol.445 , pp. 559-562
    • Xin, H.1    Liu, D.2    Wan, M.3    Safari, A.4    Kim, H.5    Sun, W.6    O'Connor, M.S.7    Songyang, Z.8
  • 62
    • 3142679378 scopus 로고    scopus 로고
    • POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
    • Ye J.Z., Hockemeyer D., Krutchinsky A.N., Loayza D., Hooper S.M., Chait B.T., and de Lange T. POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. Genes Dev. 18 (2004) 1649-1654
    • (2004) Genes Dev. , vol.18 , pp. 1649-1654
    • Ye, J.Z.1    Hockemeyer, D.2    Krutchinsky, A.N.3    Loayza, D.4    Hooper, S.M.5    Chait, B.T.6    de Lange, T.7


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