Phosphodiesterase-4 inhibition and brain tumor growth

Clinical Cancer Research

Volumn 15, Issue 9, 2009, Pages 3238-

  Schmidt, Anna Laura ^a   De Farias, Caroline Brunetto ^a   Abujamra, Ana Lucia ^a   Brunetto, Algemir Lunardi ^a   Schwartsmann, Gilberto ^a   Roesler, Rafael ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; PHOSPHODIESTERASE IV; ROLIPRAM; PHOSPHODIESTERASE INHIBITOR;

ASTROCYTE; ASTROCYTOMA; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG EFFICACY; ENZYME INHIBITION; GLIOBLASTOMA; HUMAN; LETTER; MEDULLOBLASTOMA; PRIORITY JOURNAL; TUMOR GROWTH; ANIMAL; BRAIN TUMOR; CEREBELLUM TUMOR; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM; MOUSE; NOTE;

ANIMALS; BRAIN NEOPLASMS; CEREBELLAR NEOPLASMS; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; MEDULLOBLASTOMA; MICE; PHOSPHODIESTERASE INHIBITORS; ROLIPRAM;

EID: 65649125259     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-09-0097     Document Type: Letter

References (2)

1. Goldhoff P, Warrington NM, Limbrick DD, Jr., et al. Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression. Clin Cancer Res 2008;14:7717-7725
2. Farias CB, Lima RC, Lima LO, et al. Stimulation of proliferation of U138-MG glioblastoma cells by gastrin-releasing peptide in combination with agents that enhance cAMP signaling. Oncology 2008;75:27-31.