-
2
-
-
0036713917
-
Rational cytokine design for increased lifetime and enhanced potency using pH-activated histidine switching
-
Sarkar, C. A., Lowenhaupt, K., Horan, T., Boone, T. C., Tidor, B., and Lauffenburger, D. A. (2002) Rational cytokine design for increased lifetime and enhanced potency using pH-activated "histidine switching". Nat. Biotechnol. 20, 908-913.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 908-913
-
-
Sarkar, C.A.1
Lowenhaupt, K.2
Horan, T.3
Boone, T.C.4
Tidor, B.5
Lauffenburger, D.A.6
-
3
-
-
33846794839
-
Inhibition of transferrin iron release increases in vitro drug carrier efficacy
-
Lao, B. J., Tsai, W. L., Mashayekhi, F., Pham, E. A., Mason, A. B., and Kamei, D. T. (2007) Inhibition of transferrin iron release increases in vitro drug carrier efficacy. J. Control. Release 117, 403-412.
-
(2007)
J. Control. Release
, vol.117
, pp. 403-412
-
-
Lao, B.J.1
Tsai, W.L.2
Mashayekhi, F.3
Pham, E.A.4
Mason, A.B.5
Kamei, D.T.6
-
4
-
-
13844267123
-
Integrating cell-level kinetic modeling into the design of engineered protein therapeutics
-
Rao, B. M., Lauffenburger, D. A., and Wittrup, K. D. (2005) Integrating cell-level kinetic modeling into the design of engineered protein therapeutics. Nat. Biotechnol. 23, 191-194.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 191-194
-
-
Rao, B.M.1
Lauffenburger, D.A.2
Wittrup, K.D.3
-
5
-
-
0344876636
-
Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas
-
Weaver, M. and Laske, D. W. (2003) Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas. J. Neurooncol. 65, 3-13.
-
(2003)
J. Neurooncol.
, vol.65
, pp. 3-13
-
-
Weaver, M.1
Laske, D.W.2
-
6
-
-
2042546096
-
Balancing acts: Molecular control of mammalian iron metabolism
-
Hentze, M. W., Muckenthaler, M. U., and Andrews, N. C. (2004) Balancing acts: Molecular control of mammalian iron metabolism. Cell 117, 285-297.
-
(2004)
Cell
, vol.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
7
-
-
10744222698
-
Engineered human IgG antibodies with longer serum half-lives in primates
-
Hinton, P. R., Johlfs, M. G., Xiong, J. M., Hanestad, K., Ong, K. C., Bullock, C., Keller, S., Tang, M. T., Tso, J. Y., Vasquez, M., and Tsurushita, N. (2004) Engineered human IgG antibodies with longer serum half-lives in primates. J. Biol. Chem. 279, 6213-6216.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 6213-6216
-
-
Hinton, P.R.1
Johlfs, M.G.2
Xiong, J.M.3
Hanestad, K.4
Ong, K.C.5
Bullock, C.6
Keller, S.7
Tang, M.T.8
Tso, J.Y.9
Vasquez, M.10
Tsurushita, N.11
-
8
-
-
0020550999
-
Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents
-
Ciechanover, A., Schwartz, A. L., Dautry-Varsat, A., and Lodish, H. F. (1983) Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents. J. Biol. Chem. 258, 9681-9689.
-
(1983)
J. Biol. Chem
, vol.258
, pp. 9681-9689
-
-
Ciechanover, A.1
Schwartz, A.L.2
Dautry-Varsat, A.3
Lodish, H.F.4
-
9
-
-
0028656441
-
Quantitative analysis of protein synthesis inhibition by transferrin-toxin conjugates
-
Yazdi, P. T. and Murphy, R. M. (1994) Quantitative analysis of protein synthesis inhibition by transferrin-toxin conjugates. Cancer Res. 54, 6387-6394.
-
(1994)
Cancer Res
, vol.54
, pp. 6387-6394
-
-
Yazdi, P.T.1
Murphy, R.M.2
-
10
-
-
0030743087
-
Controlling receptor/ligand trafficking: Effects of cellular and molecular properties on endosomal sorting
-
French, A. R. and Lauffenburger, D. A. (1997) Controlling receptor/ligand trafficking: Effects of cellular and molecular properties on endosomal sorting. Ann. Biomed. Eng. 25, 690-707.
-
(1997)
Ann. Biomed. Eng
, vol.25
, pp. 690-707
-
-
French, A.R.1
Lauffenburger, D.A.2
-
11
-
-
28844434252
-
Quantitative methods for developing Fc mutants with extended half-lives
-
Kamei, D. T., Lao, B. J., Ricci, M. S., Deshpande, R., Xu, H., Tidor, B., and Lauffenburger, D. A. (2005) Quantitative methods for developing Fc mutants with extended half-lives. Biotechnol. Bioeng. 92, 748-760.
-
(2005)
Biotechnol. Bioeng
, vol.92
, pp. 748-760
-
-
Kamei, D.T.1
Lao, B.J.2
Ricci, M.S.3
Deshpande, R.4
Xu, H.5
Tidor, B.6
Lauffenburger, D.A.7
-
12
-
-
0032478524
-
Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor
-
Lebron, J. A., Bennett, M. J., Vaughn, D. E., Chirino, A. J., Snow, P. M., Mintier, G. A., Feder, J. N., and Bjorkman, P. J. (1998) Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Cell 93, 111-123.
-
(1998)
Cell
, vol.93
, pp. 111-123
-
-
Lebron, J.A.1
Bennett, M.J.2
Vaughn, D.E.3
Chirino, A.J.4
Snow, P.M.5
Mintier, G.A.6
Feder, J.N.7
Bjorkman, P.J.8
-
13
-
-
35148855712
-
Computational design of antibodyaffinity improvement beyond in vivo maturation
-
Lippow, S. M., Wittrup, K. D., and Tidor, B. (2007) Computational design of antibodyaffinity improvement beyond in vivo maturation. Nat. Biotechnol. 25, 1171-1176.
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 1171-1176
-
-
Lippow, S.M.1
Wittrup, K.D.2
Tidor, B.3
-
14
-
-
2342574817
-
The oxalate effect on release of iron from human serum transferrin explained
-
Halbrooks, P. J., Mason, A. B., Adams, T. E., Briggs, S. K., and Everse, S. J. (2004) The oxalate effect on release of iron from human serum transferrin explained. J. Mol. Biol. 339, 217-226 .
-
(2004)
J. Mol. Biol
, vol.339
, pp. 217-226
-
-
Halbrooks, P.J.1
Mason, A.B.2
Adams, T.E.3
Briggs, S.K.4
Everse, S.J.5
|