Relationship between expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4+ T cells and spontaneous abortion in mice

Chinese Medical Journal

Volumn 122, Issue 4, 2009, Pages 390-395

  Jiang, Pei Juan ^a   Lin, Qi De ^a   Bao, Shi Min ^b   Zhao, Ai Min ^a   Zhang, Yu ^a   Xiao, Shi Jin ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Abortion, spontaneous; CCR3; CCR5; CD4 positive T lymphocytes; CXCR3; Receptors

Indexed keywords

CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR3; CXCR3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; EMBRYO RESORPTION; FEMALE; GENETIC ASSOCIATION; MALE; MOUSE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SPONTANEOUS ABORTION; TISSUE DISTRIBUTION; ANIMAL; BAGG ALBINO MOUSE; EMBRYO DEATH; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; METABOLISM; PREGNANCY; SPLEEN; THYMUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; EMBRYO LOSS; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED BALB C; PREGNANCY; RECEPTORS, CCR3; RECEPTORS, CCR5; RECEPTORS, CXCR3; SPLEEN; THYMUS GLAND;

EID: 65649115066     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2009.04.007     Document Type: Article

References (16)

1. Lim KJH, Odukoya OA, Ajjan RA, Li T, Weetman AP, Cooke ID. The role of T-helper cytokines in human reproduction. Fertil Steril 2000; 73: 136-142.
2. Marzi M, Vigano A, Trabattoni D, Villa ML, Salvaggio A, Clerici E. Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy. Clin Exp Immunol 1996; 106: 127-133.
3. Raghupathy R. Th1-type immunity is incompatible with successful pregnancy. Immunol Today 1997; 18: 478-482.
4. Raghupathy R, Makhseed M, Azizieh F, Hassan N, Al-Azemi M, Al-Shamali E. Maternal Th1- and Th2-type reactivity to placental antigens in normal human pregnancy and unexplained recurrent spontaneous abortions. Cell Immunol 1999; 196: 122-130.
5. Hill JA, Polgar K, Anderson DJ. T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortion. JAMA 1995; 273: 1933-1936.
6. Chantakru S, Miller C, Roach LE, Kuziel WA, Maeda N, Wang WC, et al. Contributions from self-renewal and trafficking to the uterine NK cell population of early pregnancy. J Immunol 2002; 168: 22-28.
7. +T lymphocytes into human decidual at early pregnancy. Am J Reprod Immunol 2002; 48: 1-8.
8. Hannan NJ, Jones RL, Critchley HO, Kovacs GJ, Roqers PA, Affandi B, et al. Coexpression of fractalkine andits receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role for fractalkine in leukocyte recruitment and endometrial remodeling. J Clin Endocrinol Metab 2004; 89: 6119-6129.
9. Clark DA, McDermott M, Sczewzuk MR. Impairment of host vs graft reaction in pregnant mice. II. Selective suppression of ? cytotoxic cell generation correlates with soluble suppressor activity and with successful allogeneic pregnancy. Cell Immunol 1980; 52: 106-118.
10. Zhao AM, Lin QD. Relation of Th1 and Th2 cytokine and recurrent spontaneous abortion. Acta Univ Med Second Shanghai (Chin) 2000; 20: 16-18.
11. Sallusto F, Lanzavecchia A, Mackay CR. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today 1998; 19: 568-574.
12. Kim CH, Broxmeyer HE. Chemokines: signal lamps for trafficking of T and B cells for development and effector function. J Leukoc Biol 1999; 65: 6-15.
13. Loetscher P, Uguccioni M, Bordoli L, Baqqiolini M, Moser B, Chizzolini C, et al. CCR5 is characteristic of Th1 lymphocytes. Nature 1998; 391: 344-345.
14. Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998; 187: 875-883.
15. Ruth JH , Lukacs NW, Warmington KS , Polak TJ, Burdick M, Kunkel SL, et al. Expression and participation of eotaxin during mycobacterial (type 1) and schistosomal (type 2) antigen-elicited granuloma formation. J Immunol 1998; 161: 4276-4282.
16. + T cells. J Leukoc Biol 2000; 68: 568-574.