A two-step one-pot radiosynthesis of the potent dopamine D 2/D3 agonist PET radioligand [11C]MNPA

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 52, Issue 5, 2009, Pages 158-165

  Steiger, C ^a   Finnema, S J ^a   Raus, L ^b   Schou, M ^a,c   Nakao, R ^d   Suzuki, K ^d   Pike, V W ^e   Wikstrom H V ^f   Halldin, C ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF TARTU   (Estonia)

^c ASTRAZENECA R AND D   (Sweden)

^d NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^e NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^f Allbay AB   (Sweden)

Author keywords

Dopamine D2 D3 agonist; LC MS MS analysis; MNPA; PET; Radiosynthesis

Indexed keywords

AMINES; CHLORINE COMPOUNDS; METHYLATION; NEUROPHYSIOLOGY; PROTON IRRADIATION;

DOPAMINE; DOPAMINE D2/D3 AGONIST; LC-MS-MS; LC-MS/MS ANALYSE; METHOXY; MNPA; MS/MS ANALYSIS; ONE POT; RADIOLIGANDS; RADIOSYNTHESIS;

ALKYLATION;

CATECHOL; CHLORIDE; CODEINE; DOPAMINE 2 RECEPTOR STIMULATING AGENT; DOPAMINE 3 RECEPTOR STIMULATING AGENT; HYDROGEN; NITROGEN; PROPYLNORAPOMORPHINE; PROPYLNORAPOMORPHINE DERIVATIVE C 11; UNCLASSIFIED DRUG;

ARTICLE; HEATING; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHYLATION; ONE POT SYNTHESIS; POSITRON EMISSION TOMOGRAPHY; PROTON RADIATION; RADIOSENSITIVITY;

EID: 65649113205     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1583     Document Type: Article

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