Factors associated with the prevalence and incidence of herpes simplex virus type 2 infection among men in rakai, uganda

Journal of Infectious Diseases

Volumn 199, Issue 7, 2009, Pages 945-949

  Tobian, Aaron A R ^a   Charvat, Blake ^c   Ssempijja, Victor ^e   Kigozi, Godfrey ^f   Serwadda, David ^f   Makumbi, Frederick ^f   Iga, Boaz ^e   Laeyendecker, Oliver ^b,d   Riedesel, Melissa ^d   Oliver, Amy ^b   Chen, Michael Z ^c   Reynolds, Steven J ^b,d   Wawer, Maria J ^c   Gray, Ronald H ^c   Quinn, Thomas C ^b,d  

^a Department of Pathology ^*  (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e RAKAI HEALTH SCIENCES PROGRAM   (Uganda)

^f MAKERERE UNIVERSITY   (Uganda)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE DISTRIBUTION; ALCOHOL CONSUMPTION; ARTICLE; CIRCUMCISION; CLINICAL TRIAL; CONDOM; CONTROLLED STUDY; EDUCATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENITAL HERPES; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PRIORITY JOURNAL; REAGIN TEST; RISK FACTOR; SEROPREVALENCE; SEXUAL BEHAVIOR; SEXUAL INTERCOURSE; SYPHILIS; UGANDA;

ADOLESCENT; ADULT; ALCOHOL DRINKING; CIRCUMCISION, MALE; CONDOMS; CONFIDENCE INTERVALS; HERPES GENITALIS; HERPESVIRUS 2, HUMAN; HIV SEROPOSITIVITY; HIV-1; HIV-2; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PREVALENCE; RISK FACTORS; SEXUAL BEHAVIOR; UGANDA; YOUNG ADULT;

EID: 65649108559     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/597074     Document Type: Article

References (15)

1. Gupta R, Warren T, Wald A. Genital herpes. Lancet 2007; 370:2127-37.
2. Watson-Jones D, Weiss HA, Rusizoka M, et al. Effect of herpes simplex suppression on incidence of HIV among women in Tanzania. N Engl J Med 2008; 358:1560-71.
3. Rebbapragada A, Wachihi C, Pettengell C, et al. Negative mucosal synergy between herpes simplex type 2 and HIV in the female genital tract. AIDS 2007; 21:589-98.
4. Holmberg SD, Stewart JA, Gerber AR, et al. Prior herpes simplex virus type 2 infection as a risk factor for HIV infection. JAMA 1988; 259: 1048-50.
5. Schacker T, Ryncarz AJ, Goddard J, Diem K, Shaughnessy M, Corey L. Frequent recovery of HIV-1 from genital herpes simplex virus lesions in HIV-1-infected men. JAMA 1998; 280:61-6.
6. O'Farrell N, Moodley P, Sturm AW. Genital herpes in Africa: time to rethink treatment. Lancet 2007; 370:2164-6.
7. Tassiopoulos KK, SeageG3rd, Sam N, et al. Predictors of herpes simplex virus type 2 prevalence and incidence among bar and hotel workers in Moshi, Tanzania. J Infect Dis 2007; 195:493-501.
8. Gray RH, Kigozi G, Serwadda D, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet 2007; 369: 657-66.
9. Tobian AAR, Serwadda D, Quinn TC, et al. Efficacy of male circumcision for HSV-2, syphilis, and HPV prevention. N Engl J Med (in press).
10. Gamiel JL, Tobian AAR, Laeyendecker OB, et al. Improved performance of enzyme-linked immunosorbent assays and the effect of human immunodeficiency virus coinfection on the serologic detection of herpes simplex virus type 2 in Rakai, Uganda. Clin Vaccine Immunol 2008; 15: 888-90.
11. Mehta SD, Moses S, Agot K, et al. Herpes simplex virus type 2 infection among young uncircumcised men in Kisumu, Kenya. Sex Transm Infect 2008; 84:42-8.
12. Lama JR, Lucchetti A, Suarez L, et al. Association of herpes simplex virus type 2 infection and syphilis with human immunodeficiency virus infection among men who have sex with men in Peru. J Infect Dis 2006; 194: 1459-66.
13. Laeyendecker O, Henson C, Gray RH, et al. Performance of a commercial, type-specific enzyme-linked immunosorbent assay for detection of herpes simplex virus type 2-specific antibodies in Ugandans. J Clin Microbiol 2004; 42:1794-6.
14. Gwanzura L, McFarland W, Alexander D, Burke RL, Katzenstein D. Association between human immunodeficiency virus and herpes simplex virus type 2 seropositivity among male factory workers in Zimbabwe. J Infect Dis 1998; 177:481-4.
15. McFarland W, Gwanzura L, Bassett MT, et al. Prevalence and incidence of herpes simplex virus type 2 infection among male Zimbabwean factory workers. J Infect Dis 1999; 180:1459-65.