Prognostic impact of mitotic index of proliferating cell populations in cervical cancer patients treated with carbon ion beam

Cancer

Volumn 115, Issue 9, 2009, Pages 1875-1882

  Suzuki, Yoshiyuki ^a   Oka, Kuniyuki ^b   Ohno, Tatsuya ^c   Kato, Shingo ^d   Tsujii, Hirohiko ^d   Nakano, Takashi ^a  

^a GUNMA UNIVERSITY   (Japan)

^b Mito Saiseikai General Hospital   (Japan)

^c GUNMA UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Carbon ion beam; Cervix; Ki 67; Mitotic index; Squamous cell carcinoma

Indexed keywords

EOSIN; HEMATOXYLIN; KI 67 ANTIGEN;

ADULT; AGED; ARTICLE; CALCULATION; CANCER PATIENT; CELL POPULATION; CELL PROLIFERATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; ION THERAPY; JAPAN; LABELING INDEX; METHODOLOGY; MITOSIS INDEX; MULTIVARIATE ANALYSIS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE; RADIOLOGY; SCIENCE; STAINING; TISSUE SECTION; TUMOR VOLUME; UTERINE CERVIX CANCER; UTERINE SQUAMOUS CELL CARCINOMA;

ADULT; AGED; CARBON; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; DISEASE-FREE SURVIVAL; FEMALE; HEAVY IONS; HUMANS; KI-67 ANTIGEN; MIDDLE AGED; MITOTIC INDEX; PROGNOSIS; UTERINE CERVICAL NEOPLASMS;

EID: 65649089820     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.24189     Document Type: Article

References (47)

1. Schulz-Ertner D. Tsujii H. Particle radiation therapy using proton and heavier ion beams. J Clin Oncol 2007;25:953-964. (Pubitemid 350002861)
2. Mizoe J. Tsujii H. Kamada T. et al. Dose escalation study of CIRT for locally advanced head and neck cancer. Int J Radiat Oncol Biol Phys. 2004;60:358-364.
3. Miyamoto T. Yamamoto N. Nishimura H. et al. CIRT for stage I non-small cell lung cancer. Radiother Oncol 2003;66:127-140.
4. Miyamoto T. Baba M. Yamamoto N. Working Group for Lung Cancer. Curative treatment of stage I non-small-cell lung cancer with carbon ion beams using a hypofractionated regimen. Int J Radiat Oncol Biol Phys. 2007;67:750-758.
5. Kato H. Tsujii H. Miyamoto T. et al. Results of the first prospective study of CIRT for hepatocellular carcinoma with liver cirrhosis. Int J Radiat Oncol Biol Phys, 2004;59:1468-1476. (Pubitemid 38954070)
6. Tsuji H. Ishikawa H. Yanagi T. Working Group for Ophthalmologic Tumors. Carbon-ion radiotherapy for locally advanced or unfavorably located choroidal melanoma. Int J Radiat Oncol Biol Phys. 2007;67:857-862. (Pubitemid 46215870)
7. Tsuji H. Yanagi T. Ishikawa H. et al. Hypofractionated radiotherapy with carbon ion beams for prostate cancer. Int J Radiat Oncol Biol Phys. 2005:63:1153-1160. (Pubitemid 41505295)
8. Ishikawa H. Tsuji H. Kamada T. Working Group for Genitourinary Tumors. Carbon ion radiation therapy for prostate cancer. Radiother Oncol. 2006;81:57-64. (Pubitemid 44512056)
9. Kamada T, T sujii H. Tsuji H. et al. Efficacy and safety or CIRT in bone and soft tissue sarcomas. J Clin Oncol 2002;20:4466-4471.
10. Imai R. Kamada T. Tsujii H. et al. CIRT for unresectable sacral chordomas. Clin Cancer Res. 2004;10:5741-5746.
11. Nakano T. Suzuki M. Abe A. et al. The phase I/II clinical study of carbon ion therapy for cancer of the uterine cervix. Cancer J Sci Am. 1999;5:362-369. (Pubitemid 30022429)
12. Kato S. Ohno T. Tsujii H. Working Group of the Gynecological Tumor. Dose escalation study of carbon ion radiotherapy for locally advanced carcinoma of the uterine cervix, Int J Radiat Oncol Biol Phys. 2006;65:388-397.
13. Nakano T. Suzuki Y. Ohno T. et al. Carbon beam therapy overcomes hypoxia-originating radiation-resistant nature of uterine cervical cancer. Clinical Cancer Res. 2006;12:2185-2190.
14. Filiz G. Yalcinkaya O. Gurel S. Yerci O. Memik F. The relationship between MIB-1 proliferative activity and mitotic index in gastrointestinal stromal tumors. Hepatogastroenterology. 2007;54:438-441. (Pubitemid 46724700)
15. Luukkaa H. Klemi P. Leivo I. Vahlberg T. Grenman R. Prognostic significance of Ki-67 and p53 as tumor markers in salivary gland malignancies in Finland. Acta Oncol. 2006;45:669-675. (Pubitemid 43129532)
16. Huang C. Liu D. Masuya D. et al. Clinical application of biological markers for treatments of resectable non-small-cell lung cancers. Br J Cancer. 2005:92:1231-1239. (Pubitemid 40604397)
17. Watanabe J. Kushihata F. Honda K. et al. Prognostic significance of Bcl-xL in human hepatocellular carcinoma. Surgery. 2004;135:604-612. (Pubitemid 38879343)
18. Lundgren C. Auer G. Frankendal B. Nilsson B. Nordstrom B. Prognostic factors in surgical stage 1 endometrial carcinoma. Acta Oncol. 2004;43:49-56. (Pubitemid 38283173)
19. Tortosa A. Vinolas N. Villa S. et al. Prognostic implication of clinical, radiologic, and pathologic features in patients with anaplastic gliomas. Cancer, 2003;97:1063-1071. (Pubitemid 36173159)
20. Hommura F. Dosaka-Akita H. Mishina T. et al. Prognostic significance of p27KIP1 protein and ki-67 growth fraction in non-small cell lung cancers. Clin Cancer Res. 2000;6: 4073-4081. (Pubitemid 30064970)
21. Maiurl F. De Caro Mdel B. Esposito F. et al. Recurrences of meningiomas. J Neurooncol. 2007;82:63-68.
22. Kim Y. J. Ketter R. Henn W. Zang K. D. Steudel W. I. Feiden W. Histopathologic indicators of recurrence In meningiomas: correlation with clinical and genetic parameters. Virchows Arch. 2006;449:529-538.
23. Kim Y. J. Ketter R. Steudel W. I. Feiden W. Prognostic significance of die mitotic index using the mitosis marker anti-phosphohistone H3 in meningiomas. Am J Clin Pathol 2007;128:118-125. (Pubitemid 47121724)
24. Lin C. N. Chou S. C. LI C. F. et al. Prognostic factors of myxofibrosarcomas: implications of margin status, tumor necrosis, and mitotic rate on survival. J Surg Oncol 2006;93: 294-303. (Pubitemid 43083431)
25. Azzola M. F. Shaw H. M. Thompson J. F. et al. Tumor mitotic rate is a more powerful prognostic indicator than ulceration in patients with primary cutaneous melanoma. Cancer. 2003;97:1488-1498. (Pubitemid 36613052)
26. Mandard A. M. Denoux Y. Herlin P. et al. Prognostic value of DNA cytometry in 281 premenopausal patients with lymph node negative breast carcinoma randomized in a control trial. Cancer. 2000;89:1748-1757.
27. Pietilainen T. Lipponen P. Aaltomaa S. Eskelinen M. Kosma V. M. Syrjanen K. Expression of p53 protein has no independent prognostic value in breast cancer. J Pathol 1995;177:225-232.
28. Malmstrom H. Hogberg T. Risberg B. Simonsen E. Granulosa cell tumors of the ovary: prognostic factors and outcome. Gynecol Oncol 1994;52:50-55.
29. Thor A. D. Liu S. Moore DH I. I. Edgerton SM. Comparison of mitotic index, in vitro bromodeoxyuridlne labeling, and MIB-1 assays to quantitate proliferation in breast cancer. J Clin Oncol. 1999;17:470-477. (Pubitemid 29075230)
30. Nakano T. Oka K. Differential values of Ki-67 index and mitotic index of proliferating cell population. Cancer. 1993;72:2401-2408.
31. Nakano T. Oka K. Ishikawa A. Morita S. Immunohistochemical prediction of radiation response and local control in radiation therapy for cervical cancer. Cancer Detect Prev. 1998;22:120-128. (Pubitemid 28159333)
32. Nakano T. Oka K. Ishikawa A. Morita S. Correlation of cervical carcinoma c-erb B-2 oncogene with cell proliferation parameters in patients treated with radiation therapy for cervical carcinoma. Cancer. 1997;79:513-520. (Pubitemid 27051776)
33. Richter M. P. Laramore G. E. Griffin T. W. Goodman RL. Current status of high linear energy transfer irradiation. Cancer. 1984;54 (suppl):2814-2822. (Pubitemid 15187422)
34. Blakely E. Chang P. Lommel L. et al. Cell-cycle radiation response. Adv Space Res. 1989;9:177-186.
35. Barendsen G. W. Van Bree C. Franken NA. Importance of cell proliferative state and potentially lethal damage repair on radiation effectiveness. Int J Oncol 2001;19: 247-256. (Pubitemid 33355464)
36. Takahashi A. Matsumoto H. Yuki K. et al. High-LET radiation enhanced apoptosis but not necrosis regardless of p53 status. Int J Radiat Oncol Biol Phys. 2004;60:591-597. (Pubitemid 39233481)
37. Ascher S. M. Imaoka I. Hricak H. Diagnostic imaging techniques in gynecologic oncology. In: Hoskins W. J. Perez C. A. Young R. C. eds. Principles and Practice of Gynecologic Oncology. 3rd ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2000:629-668.
38. Mayr N. A. Yuh W. T. C. Zheng J. et al. Tumor size evaluated by pelvic examination compared with 3-D quantitative analysis in the prediction of outcome for cervical cancer. Int J Radiat Oncol Biol Phys. 1997:39:395-404. (Pubitemid 27392506)
39. International Federation of Gynecology and Obstetrics. Annual Report on the Results of Treatment in Carcinoma of the Uterus, Vagina and Ovary. Stockholm, Sweden: FIGO; 1979.
40. Poulsen H. E. Taylor C. W. Sobin LH. Histological Typing of Female Genital Tract Tumors. Geneva, Switzerland: World Health Organization; 1975.
41. Kanai T. Matsufuji N. Miyamoto T. et al. Examination of GyE system for HIMAC carbon therapy. Int J Radiat Oncol Biol Phys. 2006;64:650-656. (Pubitemid 43083456)
42. Takeuchi H. Ozawa S. Ando N. Kitagawa Y. Ueda M. Kitajima M. Cell-cycle regulators and the Ki-67 labeling index can predict the response to chemoradiotherapy and the survival of patients with locally advanced squamous cell carcinoma of the esophagus. Ann Surg Oncol. 2003;10:792-800. (Pubitemid 40486880)
43. Ohno T. Nakano T. Kato S. et al. Accelerated hyperfractionated radiotherapy for cervical cancer: multi-institutional prospective study of forum for nuclear cooperation in Asia among 8 Asian countries. Int J Radiat Oncol Biol Phys. 2008;70:1522-1529.
44. Kavanagh B. D. Segreti E. M. Koo D. et al. Long-term local control and survival after concomitant boost accelerated radiotherapy for locally advanced cervix cancer. Am J Clin Oncol. 2001;24:113-119. (Pubitemid 32323344)
45. Rose P. G. Bundy B. N. Watkins E. B. et al. Concurrent cisplatin-based radiodierapy and chemodierapy for locally advanced cervical cancer. N Engl J Med. 1999:340:1144-1153. (Pubitemid 29177873)
46. Eifel P. J. Winter K. Morris M. et al. Pelvic irradiation with concurrent chemodierapy versus pelvic and para-aortic irradiation for high-risk cervical cancer: an update of Radiation Therapy Oncology Group Trial (RTOG) 90-01. J Clin Oncol 2004;22:872-880. (Pubitemid 41103599)
47. Ando K. Koike S. Ohira C. et al. Accelerated reoxygenation of a murine fibrosarcoma after carbon-ion radiation. Int J Radiat Biol. 1999;75:505-512. (Pubitemid 29191549)