-
1
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975;256:495-497
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
2
-
-
42949106166
-
Monoclonal antibodies in cancer therapy: 25 Years of progress
-
A review detailing the field of monoclonal antibody therapies in the past 25 years
-
Oldham RK, Dillman RO. Monoclonal antibodies in cancer therapy: 25 years of progress. J Clin Oncol 2008;26:1774-7 • A review detailing the field of monoclonal antibody therapies in the past 25 years.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1774-1777
-
-
Oldham, R.K.1
Dillman, R.O.2
-
4
-
-
45149122101
-
Newer monoclonal antibodies for hematological malignancies
-
DOI 10.1016/j.exphem.2008.04.018, PII S0301472X08002075
-
Castillo J, Winer E, Quesenberry P. Newer monoclonal antibodies for hematological malignancies. Exp Hematol 2008;36:755-768 (Pubitemid 351826873)
-
(2008)
Experimental Hematology
, vol.36
, Issue.7
, pp. 755-768
-
-
Castillo, J.1
Winer, E.2
Quesenberry, P.3
-
5
-
-
48049118634
-
Approved monoclonal antibodies for cancer therapy
-
Boyiadzis M, Foon KA. Approved monoclonal antibodies for cancer therapy. Expert Opin Biol Ther 2008;8:1151-1158
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 1151-1158
-
-
Boyiadzis, M.1
Foon, K.A.2
-
6
-
-
39749096242
-
VEGF polymorphisms and survival in early-stage non-small-cell lung cancer
-
Heist RS, Zhai R, Liu G, et al. VEGF polymorphisms and survival in early-stage non-small-cell lung cancer. J Clin Oncol 2008;26:856-862
-
(2008)
J Clin Oncol
, vol.26
, pp. 856-862
-
-
Heist, R.S.1
Zhai, R.2
Liu, G.3
-
7
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Study leading to the first FDA approval of Bevacizumab
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-42 •• Study leading to the first FDA approval of Bevacizumab.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
8
-
-
34248173883
-
Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
-
DOI 10.1200/JCO.2006.09.6305
-
Giantonio BJ, Catalano PJ, Meropol N, et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 2007;25:1539-1544 (Pubitemid 46733080)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.12
, pp. 1539-1544
-
-
Giantonio, B.J.1
Catalano, P.J.2
Meropol, N.J.3
O'Dwyer, P.J.4
Mitchell, E.P.5
Alberts, S.R.6
Schwartz, M.A.7
Benson III, A.B.8
-
9
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
DOI 10.1056/NEJMoa061884
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006;355:2542-2550 (Pubitemid 44917502)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowlati, A.6
Lilenbaum, R.7
Johnson, D.H.8
-
10
-
-
45849133426
-
Bevacizumab for the treatment of advanced non-small-cell lung cancer
-
Manegold C. Bevacizumab for the treatment of advanced non-small-cell lung cancer. Expert Rev Anticancer Ther 2008;8:689-699
-
(2008)
Expert Rev Anticancer Ther
, vol.8
, pp. 689-699
-
-
Manegold, C.1
-
11
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
DOI 10.1200/JCO.2005.05.098
-
Miller KD, Chap LI, Holmes FA, et al. Randomized Phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 2005;23:792-799 (Pubitemid 46224178)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.4
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Holmes, F.A.3
Cobleigh, M.A.4
Marcom, P.K.5
Fehrenbacher, L.6
Dickler, M.7
Overmoyer, B.A.8
Reimann, J.D.9
Sing, A.P.10
Langmuir, V.11
Rugo, H.S.12
-
12
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007;357:2666-2676
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
13
-
-
42049112958
-
Correlation between rash and a positive drug response associated with bevacizumab in a patient with advanced colorectal cancer
-
Saif MW, Longo WL, Israel G. Correlation between rash and a positive drug response associated with bevacizumab in a patient with advanced colorectal cancer. Clin Colorectal Cancer 2008;7:144-148
-
(2008)
Clin Colorectal Cancer
, vol.7
, pp. 144-148
-
-
Saif, M.W.1
Longo, W.L.2
Israel, G.3
-
14
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
-
DOI 10.1016/S0140-6736(07)61904-7, PII S0140673607619047
-
Escudier B, Pluzanska A, Koralewski P, et al. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007;370:2103-2111 (Pubitemid 350296300)
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
Ravaud, A.4
Bracarda, S.5
Szczylik, C.6
Chevreau, C.7
Filipek, M.8
Melichar, B.9
Bajetta, E.10
Gorbunova, V.11
Bay, J.-O.12
Bodrogi, I.13
Jagiello-Gruszfeld, A.14
Moore, N.15
-
15
-
-
49249113484
-
Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity
-
Azad NS, Posadas EM, Kwitkowski VE, et al. Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. J Clin Oncol 2008;26:3709-3714
-
(2008)
J Clin Oncol
, vol.26
, pp. 3709-3714
-
-
Azad, N.S.1
Posadas, E.M.2
Kwitkowski, V.E.3
-
16
-
-
52949097293
-
Bevacizumab: A treatment option for recurrent glioblastoma multiforme
-
Buie LW, Valgus J. Bevacizumab: a treatment option for recurrent glioblastoma multiforme. Ann Pharmacother 2008;42:1486-1490
-
(2008)
Ann Pharmacother
, vol.42
, pp. 1486-1490
-
-
Buie, L.W.1
Valgus, J.2
-
17
-
-
46449091500
-
Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma
-
Siegel AB, Cohen EI, Ocean A, et al. Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma. J Clin Oncol 2008;26:2992-2998
-
(2008)
J Clin Oncol
, vol.26
, pp. 2992-2998
-
-
Siegel, A.B.1
Cohen, E.I.2
Ocean, A.3
-
18
-
-
84969305913
-
HER2 genetic polymorphism and pharmacodynamics of trastuzumab-based treatment in breast cancer patients
-
ASCO Annual Meeting Proceedings
-
Milano GA, Lescault W, Formento JL, et al. HER2 genetic polymorphism and pharmacodynamics of trastuzumab-based treatment in breast cancer patients. ASCO Annual Meeting Proceedings. J Clin Oncol 2005;23(16S):501
-
(2005)
J Clin Oncol
, vol.23
, Issue.16 S
, pp. 501
-
-
Milano, G.A.1
Lescault, W.2
Formento, J.L.3
-
19
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh MA, Vogel CL, Tripathy D, et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999;17:2639-48 •• Study leading to the first FDA approval of Trastuzumab. (Pubitemid 29415219)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.9
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
Robert, N.J.4
Scholl, S.5
Fehrenbacher, L.6
Wolter, J.M.7
Paton, V.8
Shak, S.9
Lieberman, G.10
Slamon, D.J.11
-
20
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against her2 for metastatic breast cancer that overexpresses HER2
-
DOI 10.1056/NEJM200103153441101
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-792 (Pubitemid 32222155)
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
-
21
-
-
34948815141
-
Benefit from adjuvant trastuzumab may not be confined to patients with IHC 3+ and/or FISH-positive tumors: Central testing results from NSABP B-31
-
ASCO Annual Meeting Proceedings. A recent analysis suggesting that the use of trastuzumab may not be confined strictly to HER2-amplified tumors
-
Paik S, Kim C, Jeong J, et al. Benefit from adjuvant trastuzumab may not be confined to patients with IHC 3+ and/or FISH-positive tumors: Central testing results from NSABP B-31. ASCO Annual Meeting Proceedings. J Clin Oncol 2007;25(18S):511 • A recent analysis suggesting that the use of trastuzumab may not be confined strictly to HER2-amplified tumors.
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 S
, pp. 511
-
-
Paik, S.1
Kim, C.2
Jeong, J.3
-
22
-
-
46949109559
-
A Phase II study of weekly vinorelbine and trastuzumab in patients with HER2-positive metastatic breast cancer
-
DOI 10.3816/CBC.2008.n.030
-
Bayo-Calero JL, Mayordomo JI, Sanchez-Rovira P, et al. A Phase II study of weekly vinorelbine and trastuzumab in patients with HER2-positive metastatic breast cancer. Clin Breast Cancer 2008;8:264-268 (Pubitemid 351962148)
-
(2008)
Clinical Breast Cancer
, vol.8
, Issue.3
, pp. 264-268
-
-
Bayo-Calero, J.L.1
Mayordomo, J.I.2
Sanchez-Rovira, P.3
Perez-Carrion, R.4
Illaramendi, J.J.5
Garcia-Bueno, J.M.6
Gonzalez-Flores, E.7
Crespo, C.8
Ramos-Vazquez, M.9
Garcia-Palomo, A.10
Ruiz-Borrego, M.11
De La Haba, J.12
Gomez-Bernal, A.13
Yubero-Esteban, A.14
-
23
-
-
53149143875
-
Advanced bladder cancer: Status of first-line chemotherapy and the search for active agents in the second-line setting
-
Gallagher DJ, Milowsky MI, Bajorin DF. Advanced bladder cancer: status of first-line chemotherapy and the search for active agents in the second-line setting. Cancer 2008;113:1284-1293
-
(2008)
Cancer
, vol.113
, pp. 1284-1293
-
-
Gallagher, D.J.1
Milowsky, M.I.2
Bajorin, D.F.3
-
24
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Two trials leading to FDA approval of Cetuximab for head and neck cancer
-
Bonner JA, Harari PM, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006;354:567-78 •• Two trials leading to FDA approval of Cetuximab for head and neck cancer.
-
(2006)
N Engl J Med
, vol.354
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
-
25
-
-
34250180582
-
Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
-
DOI 10.1200/JCO.2006.06.7447
-
Vermorken JB, Trigo J, Hitt R, et al. Open-label, uncontrolled, multicenter Phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy. J Clin Oncol 2007;25:2171-7 •• Two trials leading to FDA approval of Cetuximab for head and neck cancer. (Pubitemid 46954639)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.16
, pp. 2171-2177
-
-
Vermorken, J.B.1
Trigo, J.2
Hitt, R.3
Koralewski, P.4
Diaz-Rubio, E.5
Rolland, F.6
Knecht, R.7
Amellal, N.8
Schueler, A.9
Baselga, J.10
-
26
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan- Refractory metastatic colorectal cancer
-
DOI 10.1056/NEJMoa033025
-
Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004;351:337-345 (Pubitemid 38944402)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.4
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
Khayat, D.4
Bleiberg, H.5
Santoro, A.6
Bets, D.7
Mueser, M.8
Harstrick, A.9
Verslype, C.10
Chau, I.11
Van Cutsem, E.12
-
27
-
-
2142641698
-
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
-
DOI 10.1200/JCO.2004.10.182
-
Saltz LB, Meropol NJ, Loehrer PJ Sr, et al. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 2004;22:1201-1208 (Pubitemid 41079832)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.7
, pp. 1201-1208
-
-
Saltz, L.B.1
Meropol, N.J.2
Loehrer Sr., P.J.3
Needle, M.N.4
Kopit, J.5
Mayer, R.J.6
-
28
-
-
36049003128
-
Current Immunotherapeutic Strategies in Pancreatic Cancer
-
DOI 10.1016/j.soc.2007.07.012, PII S1055320707000944, Tumor Immunology for the Practicing Surgeon
-
Plate JM. Current immunotherapeutic strategies in pancreatic cancer. Surg Oncol Clin N Am 2007;16:919-43, xi (Pubitemid 350101277)
-
(2007)
Surgical Oncology Clinics of North America
, vol.16
, Issue.4
, pp. 919-943
-
-
Plate, J.M.D.1
-
29
-
-
46049097410
-
Gemcitabine plus oxaliplatin (GEMOX) combined with cetuximab in patients with progressive advanced stage hepatocellular carcinoma: Results of a multicenter phase 2 study
-
DOI 10.1002/cncr.23489
-
Asnacios A, Fartoux L, Romano O, et al. Gemcitabine plus oxaliplatin (GEMOX) combined with cetuximab in patients with progressive advanced stage hepatocellular carcinoma: results of a multicenter phase 2 study. Cancer 2008;112:2733-2739 (Pubitemid 351969218)
-
(2008)
Cancer
, vol.112
, Issue.12
, pp. 2733-2739
-
-
Asnacios, A.1
Fartoux, L.2
Romano, O.3
Tesmoingt, C.4
Louafi S, S.5
Mansoubakht, T.6
Artru, P.7
Poynard, T.8
Rosmorduc, O.9
Hebbar, M.10
Taieb, J.11
-
30
-
-
37649022615
-
Randomized Phase II study of gemcitabine plus cisplatin or carboplatin [corrected], with or without cetuximab, as first-line therapy for patients with advanced or metastatic non small-cell lung cancer
-
Erratum in J Clin Oncol 2008;26(19):3295
-
Butts CA, Bodkin D, Middleman EL, et al. Randomized Phase II study of gemcitabine plus cisplatin or carboplatin [corrected], with or without cetuximab, as first-line therapy for patients with advanced or metastatic non small-cell lung cancer. J Clin Oncol 2007;25:5777-84. Erratum in J Clin Oncol 2008;26(19):3295
-
(2007)
J Clin Oncol
, vol.25
, pp. 5777-5784
-
-
Butts, C.A.1
Bodkin, D.2
Middleman, E.L.3
-
31
-
-
34547866682
-
Targeting EGFR and HER-2 with cetuximab- And trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma
-
DOI 10.1038/sj.bjc.6603885, PII 6603885
-
Kawaguchi Y, Kono K, Mimura K, et al. Targeting EGFR and HER-2 with cetuximab- and trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma. Br J Cancer 2007;97:494-501 (Pubitemid 47258449)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.4
, pp. 494-501
-
-
Kawaguchi, Y.1
Kono, K.2
Mimura, K.3
Mitsui, F.4
Sugai, H.5
Akaike, H.6
Fujii, H.7
-
32
-
-
45949083997
-
A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment
-
DOI 10.1186/1471-2407-8-169
-
Goncalves A, Esteyries S, Taylor-Smedra B, et al. A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment. BMC Cancer 2008;8:169. Published online June 10 2008, doi:10.1186/1471-2407-8-169 (Pubitemid 351891421)
-
(2008)
BMC Cancer
, vol.8
, pp. 169
-
-
Goncalves, A.1
Esteyries, S.2
Taylor-Smedra, B.3
Lagarde, A.4
Ayadi, M.5
Monges, G.6
Bertucci, F.7
Esterni, B.8
Delpero, J.-R.9
Turrini, O.10
Lelong, B.11
Viens, P.12
Borg, J.-P.13
Birnbaum, D.14
Olschwang, S.15
Viret, F.16
-
33
-
-
51649085865
-
Platinum-based chemotherapy plus cetuximab in head and neck cancer
-
Vermorken JB, Mesia R, Rivera F, et al. Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 2008;359:1116-1127
-
(2008)
N Engl J Med
, vol.359
, pp. 1116-1127
-
-
Vermorken, J.B.1
Mesia, R.2
Rivera, F.3
-
34
-
-
34147103678
-
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy- Refractory metastatic colorectal cancer
-
DOI 10.1200/JCO.2006.08.1620
-
Van Cutsem E, Peeters M, Siena S, et al. Open-label Phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol 2007;25:1658-64 •• Study leading to FDA approval of Panitumumab for the treatment of mCRC. (Pubitemid 46797944)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.13
, pp. 1658-1664
-
-
Van Cutsem, E.1
Peeters, M.2
Siena, S.3
Humblet, Y.4
Hendlisz, A.5
Neyns, B.6
Canon, J.-L.7
Van Laethem, J.-L.8
Maurel, J.9
Richardson, G.10
Wolf, M.11
Amado, R.G.12
-
35
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:1626-1634
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
36
-
-
4143050397
-
Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer
-
DOI 10.1200/JCO.2004.11.061
-
Rowinsky EK, Schwartz GH, Gollob JA, et al. Safety, pharmacokinetics, and activity of ABX-EGF, a fully human anti-epidermal growth factor receptor monoclonal antibody in patients with metastatic renal cell cancer. J Clin Oncol 2004;22:3003-3015 (Pubitemid 41103711)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.15
, pp. 3003-3015
-
-
Rowinsky, E.K.1
Schwartz, G.H.2
Gollob, J.A.3
Thompson, J.A.4
Vogelzang, N.J.5
Figlin, R.6
Bukowski, R.7
Haas, N.8
Lockbaum, P.9
Li, Y.-P.10
Arends, R.11
Foon, K.A.12
Schwab, G.13
Dutcher, J.14
-
37
-
-
34547697317
-
Antibodies to the epidermal growth factor receptor in non-small cell lung cancer: Current status of matuzumab and panitumumab
-
DOI 10.1158/1078-0432.CCR-07-0335
-
Socinski MA. Antibodies to the epidermal growth factor receptor in non small cell lung cancer: current status of matuzumab and panitumumab. Clin Cancer Res 2007;13:s4597-601 (Pubitemid 47219731)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.15
-
-
Socinski, M.A.1
-
38
-
-
49449119098
-
Antibody-drug conjugates for cancer therapy
-
Carter PJ, Senter PD. Antibody-drug conjugates for cancer therapy. Cancer J 2008;14:154-169
-
(2008)
Cancer J
, vol.14
, pp. 154-169
-
-
Carter, P.J.1
Senter, P.D.2
-
39
-
-
54049137660
-
Clinical trials of targeted alpha therapy for cancer
-
Allen BJ. Clinical trials of targeted alpha therapy for cancer. Rev Recent Clin Trials 2008;3:185-191
-
(2008)
Rev Recent Clin Trials
, vol.3
, pp. 185-191
-
-
Allen, B.J.1
-
40
-
-
17644418758
-
Radioimmunodetection and therapy of breast cancer
-
DeNardo SJ. Radioimmunodetection and therapy of breast cancer. Semin Nucl Med 2005;35:143-151
-
(2005)
Semin Nucl Med
, vol.35
, pp. 143-151
-
-
Denardo, S.J.1
-
41
-
-
52649150833
-
Targeting angiogenesis driven by vascular endothelial growth factors using antibody-based therapies
-
Grothey A, Ellis LM. Targeting angiogenesis driven by vascular endothelial growth factors using antibody-based therapies. Cancer J 2008;14:170-177
-
(2008)
Cancer J
, vol.14
, pp. 170-177
-
-
Grothey, A.1
Ellis, L.M.2
-
42
-
-
20044381863
-
Phase I investigation of recombinant anti-human vascular endothelial growth factor antibody in patients with advanced cancer
-
DOI 10.1016/j.ejca.2004.11.021
-
Jayson GC, Mulatero C, Ranson M, et al. Phase I investigation of recombinant anti-human vascular endothelial growth factor antibody in patients with advanced cancer. Eur J Cancer 2005;41:555-563 (Pubitemid 40292735)
-
(2005)
European Journal of Cancer
, vol.41
, Issue.4
, pp. 555-563
-
-
Jayson, G.C.1
Mulatero, C.2
Ranson, M.3
Zweit, J.4
Jackson, A.5
Broughton, L.6
Wagstaff, J.7
Hakansson, L.8
Groenewegen, G.9
Lawrance, J.10
Tang, M.11
Wauk, L.12
Levitt, D.13
Marreaud, S.14
Lehmann, F.F.15
Herold, M.16
Zwierzina, H.17
-
43
-
-
19044380618
-
Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
-
DOI 10.1016/S1535-6108(02)00097-1
-
Agus DB, Akita RW, Fox WD, et al. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell 2002;2:127-137 (Pubitemid 41039113)
-
(2002)
Cancer Cell
, vol.2
, Issue.2
, pp. 127-137
-
-
Agus, D.B.1
Akita, R.W.2
Fox, W.D.3
Lewis, G.D.4
Higgins, B.5
Pisacane, P.I.6
Lofgren, J.A.7
Tindell, C.8
Evans, D.P.9
Maiese, K.10
Scher, H.I.11
Sliwkowski, M.X.12
-
44
-
-
33749003463
-
Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: Potential predictive relationship with tumor HER2 activation status
-
DOI 10.1200/JCO.2005.05.4221
-
Gordon MS, Matei D, Aghajanian C, et al. Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status. J Clin Oncol 2006;24:4324-4332 (Pubitemid 46630791)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.26
, pp. 4324-4332
-
-
Gordon, M.S.1
Matei, D.2
Aghajanian, C.3
Matulonis, U.A.4
Brewer, M.5
Fleming, G.F.6
Hainsworth, J.D.7
Garcia, A.A.8
Pegram, M.D.9
Schilder, R.J.10
Cohn, D.E.11
Roman, L.12
Derynck, M.K.13
Ng, K.14
Lyons, B.15
Allison, D.E.16
Eberhard, D.A.17
Pham, T.Q.18
Dere, R.C.19
Karlan, B.Y.20
more..
-
45
-
-
35949004420
-
Efficacy and safety of single-agent pertuzumab, a human epidermal receptor dimerization inhibitor, in patients with non-small cell lung cancer
-
DOI 10.1158/1078-0432.CCR-07-0460
-
Herbst RS, Davies AM, Natale RB, et al. Efficacy and safety of single-agent pertuzumab, a human epidermal receptor dimerization inhibitor, in patients with non small cell lung cancer. Clin Cancer Res 2007;13:6175-6181 (Pubitemid 350075078)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.20
, pp. 6175-6181
-
-
Herbst, R.S.1
Davies, A.M.2
Natale, R.B.3
Dang, T.P.4
Schiller, J.H.5
Garland, L.L.6
Miller, V.A.7
Mendelson, D.8
Van Den Abbeele, A.D.9
Melenevsky, Y.10
De Vries, D.J.11
Eberhard, D.A.12
Lyons, B.13
Lutzker, S.G.14
Johnson, B.E.15
-
46
-
-
33744803712
-
Phase I trial of the trifunctional anti-HER2 x anti-CD3 antibody ertumaxomab in metastatic breast cancer
-
DOI 10.1158/1078-0432.CCR-05-2436
-
Kiewe P, Hasmuller S, Kahlert S, et al. Phase I trial of the trifunctional anti-HER2 x anti-CD3 antibody ertumaxomab in metastatic breast cancer. Clin Cancer Res 2006;12:3085-3091 (Pubitemid 43837355)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.10
, pp. 3085-3091
-
-
Kiewe, P.1
Hasmuller, S.2
Kahlert, S.3
Heinrigs, M.4
Rack, B.5
Marme, A.6
Korfel, A.7
Jager, M.8
Lindhofer, H.9
Sommer, H.10
Thiel, E.11
Untch, M.12
-
47
-
-
33646870539
-
A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC)
-
Kollmannsberger C, Schittenhelm M, Honecker F, et al. A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC). Ann Oncol 2006;17:1007-1013
-
(2006)
Ann Oncol
, vol.17
, pp. 1007-1013
-
-
Kollmannsberger, C.1
Schittenhelm, M.2
Honecker, F.3
-
48
-
-
33646504884
-
Phase I study of the humanised anti-EGFR monoclonal antibody matuzumab (EMD 72000) combined with gemcitabine in advanced pancreatic cancer
-
Graeven U, Kremer B, Sudhoff T, et al. Phase I study of the humanised anti-EGFR monoclonal antibody matuzumab (EMD 72000) combined with gemcitabine in advanced pancreatic cancer. Br J Cancer 2006;94:1293-1299
-
(2006)
Br J Cancer
, vol.94
, pp. 1293-1299
-
-
Graeven, U.1
Kremer, B.2
Sudhoff, T.3
-
49
-
-
33846950834
-
A phase II trial of EMD72000 (matuzumab), a humanized anti-EGFR monoclonal antibody, in patients with platinum-resistant ovarian and primary peritoneal malignancies
-
DOI 10.1016/j.ygyno.2006.10.019, PII S0090825806008092
-
Seiden MV, Burris HA, Matulonis U, et al. A phase II trial of EMD72000 (matuzumab), a humanized anti-EGFR monoclonal antibody, in patients with platinum-resistant ovarian and primary peritoneal malignancies. Gynecol Oncol 2007;104:727-731 (Pubitemid 46251417)
-
(2007)
Gynecologic Oncology
, vol.104
, Issue.3
, pp. 727-731
-
-
Seiden, M.V.1
Burris, H.A.2
Matulonis, U.3
Hall, J.B.4
Armstrong, D.K.5
Speyer, J.6
Weber, J.D.A.7
Muggia, F.8
-
50
-
-
37549036341
-
Current situation of Panitumumab, Matuzumab, Nimotuzumab and Zalutumumab
-
Rivera F, Vega-Villegas ME, Lopez-Brea MF, Marquez R. Current situation of Panitumumab, Matuzumab, Nimotuzumab and Zalutumumab. Acta Oncol 2008;47:9-19
-
(2008)
Acta Oncol
, vol.47
, pp. 9-19
-
-
Rivera, F.1
Vega-Villegas, M.E.2
Lopez-Brea, M.F.3
Marquez, R.4
-
51
-
-
0035872404
-
Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors
-
Modak S, Kramer K, Gultekin SH, et al. Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors. Cancer Res 2001;61:4048-4054 (Pubitemid 32720969)
-
(2001)
Cancer Research
, vol.61
, Issue.10
, pp. 4048-4054
-
-
Modak, S.1
Kramer, K.2
Gultekin, S.H.3
Guo, H.F.4
Cheung, N.-K.V.5
-
52
-
-
34548257760
-
Review: Anti-CTLA-4 antibody ipilimumab: Case studies of clinical response and immune-related adverse events
-
DOI 10.1634/theoncologist.12-7-864
-
Weber J. Review: anti-CTLA-4 antibody ipilimumab: case studies of clinical response and immune-related adverse events. Oncologist 2007;12:864-872 (Pubitemid 47328229)
-
(2007)
Oncologist
, vol.12
, Issue.7
, pp. 864-872
-
-
Weber, J.1
-
53
-
-
27844458057
-
Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: A phase I/II study
-
DOI 10.1245/ASO.2005.03.536
-
Maker AV, Phan GQ, Attia P, et al. Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a Phase I/II study. Ann Surg Oncol 2005;12:1005-1016 (Pubitemid 41660676)
-
(2005)
Annals of Surgical Oncology
, vol.12
, Issue.12
, pp. 1005-1016
-
-
Maker, A.V.1
Phan, G.Q.2
Attia, P.3
Yang, J.C.4
Sherry, R.M.5
Topalian, S.L.6
Kammula, U.S.7
Royal, R.E.8
Haworth, L.R.9
Levy, C.10
Kleiner, D.11
Mavroukakis, S.A.12
Yellin, M.13
Rosenberg, S.A.14
-
54
-
-
54349094280
-
Tremelimumab (CP-675,206): A fully human anticytotoxic T lymphocyte-associated antigen 4 monoclonal antibody for treatment of patients with advanced cancers
-
Tarhini AA, Kirkwood JM. Tremelimumab (CP-675,206): a fully human anticytotoxic T lymphocyte-associated antigen 4 monoclonal antibody for treatment of patients with advanced cancers. Expert Opin Biol Ther 2008;8:1583-1593
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 1583-1593
-
-
Tarhini, A.A.1
Kirkwood, J.M.2
-
55
-
-
55949137090
-
Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma
-
[abstract LBA9011]. ASCO Annual Meeting Proceedings. Phase III trial in which Tremelimumab failed to show an improvement in OS versus chemotherapy alone in metastatic melanoma
-
Ribas A, Hauschild A, Kefford R, et al. Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma [abstract LBA9011]. ASCO Annual Meeting Proceedings. J Clin Oncol 2008;26(suppl) •• Phase III trial in which Tremelimumab failed to show an improvement in OS versus chemotherapy alone in metastatic melanoma.
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Ribas, A.1
Hauschild, A.2
Kefford, R.3
-
56
-
-
35948952826
-
Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers
-
DOI 10.1158/1078-0432.CCR-07-0950
-
Plummer R, Attard G, Pacey S, et al. Phase 1 and pharmacokinetic study of lexatumumab in patients with advanced cancers. Clin Cancer Res 2007;13:6187-6194 (Pubitemid 350075080)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.20
, pp. 6187-6194
-
-
Plummer, R.1
Attard, G.2
Pacey, S.3
Li, L.4
Razak, A.5
Perrett, R.6
Barrett, M.7
Judson, I.8
Kaye, S.9
Fox, N.L.10
Halpern, W.11
Corey, A.12
Calvert, H.13
De Bono, J.14
-
57
-
-
50349092260
-
A Phase 1 study of mapatumumab (fully human monoclonal antibody to TRAIL-R1) in patients with advanced solid malignancies
-
Hotte SJ, Hirte HW, Chen EX, et al. A Phase 1 study of mapatumumab (fully human monoclonal antibody to TRAIL-R1) in patients with advanced solid malignancies. Clin Cancer Res 2008;14:3450-3455
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3450-3455
-
-
Hotte, S.J.1
Hirte, H.W.2
Chen, E.X.3
-
58
-
-
45649084324
-
Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer
-
Greco FA, Bonomi P, Crawford J, et al. Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer. Lung Cancer 2008;61:82-90
-
(2008)
Lung Cancer
, vol.61
, pp. 82-90
-
-
Greco, F.A.1
Bonomi, P.2
Crawford, J.3
-
59
-
-
4344618391
-
Phase I trial of yttrium-90-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for androgen-independent prostate cancer
-
DOI 10.1200/JCO.2004.09.154
-
Milowsky MI, Nanus DM, Kostakoglu L, et al. Phase I trial of yttrium-90-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for androgen-independent prostate cancer. J Clin Oncol 2004;22:2522-2531 (Pubitemid 41103739)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.13
, pp. 2522-2531
-
-
Milowsky, M.I.1
Nanus, D.M.2
Kostakoglu, L.3
Vallabhajosula, S.4
Goldsmith, S.J.5
Bander, N.H.6
-
60
-
-
22044451179
-
177Lutetium-labeled J591, a monoclonal antibody to prostate-specific membrane antigen, in patients with androgen-independent prostate cancer
-
DOI 10.1200/JCO.2005.05.160
-
Bander NH, Milowsky MI, Nanus DM, et al. Phase I trial of 177lutetium-labeled J591, a monoclonal antibody to prostate-specific membrane antigen, in patients with androgen-independent prostate cancer. J Clin Oncol 2005;23:4591-4601 (Pubitemid 46224061)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.21
, pp. 4591-4601
-
-
Bander, N.H.1
Milowsky, M.I.2
Nanus, D.M.3
Kostakoglu, L.4
Vallabhajosula, S.5
Goldsmith, S.J.6
-
61
-
-
43749092340
-
Phase I trial of the prostate-specific membrane antigen-directed immunoconjugate MLN2704 in patients with progressive metastatic castration-resistant prostate cancer
-
Galsky MD, Eisenberger M, Moore-Cooper S, et al. Phase I trial of the prostate-specific membrane antigen-directed immunoconjugate MLN2704 in patients with progressive metastatic castration-resistant prostate cancer. J Clin Oncol 2008;26:2147-2154
-
(2008)
J Clin Oncol
, vol.26
, pp. 2147-2154
-
-
Galsky, M.D.1
Eisenberger, M.2
Moore-Cooper, S.3
-
62
-
-
36148981957
-
A Phase I study of q3W R1507, a human monoclonal antibody IGF-1R antagonist in patients with advanced cancer
-
Rodon J, Patnaik A, Stein M, et al. A Phase I study of q3W R1507, a human monoclonal antibody IGF-1R antagonist in patients with advanced cancer. ASCO Meeting Abstracts 2007;25:3590
-
(2007)
ASCO Meeting Abstracts
, vol.25
, pp. 3590
-
-
Rodon, J.1
Patnaik, A.2
Stein, M.3
-
63
-
-
35348815620
-
Phase I dose escalation study of the anti-insulin-like growth factor-I receptor monoclonal antibody CP-751,871in patients with refractory solid tumors
-
DOI 10.1158/1078-0432.CCR-07-1118
-
Haluska P, Shaw HM, Batzel GN, et al. Phase I dose escalation study of the anti insulin-like growth factor-I receptor monoclonal antibody CP-751,871 in patients with refractory solid tumors. Clin Cancer Res 2007;13:5834-5840 (Pubitemid 47583908)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.19
, pp. 5834-5840
-
-
Haluska, P.1
Shaw, H.M.2
Batzel, G.N.3
Yin, D.4
Molina, J.R.5
Molife, L.R.6
Yap, T.A.7
Roberts, M.L.8
Sharma, A.9
Gualberto, A.10
Adjei, A.A.11
De Bono, J.S.12
-
64
-
-
0038383042
-
Human melanoma/NG2 chondroitin sulfate proteoglycan is expressed in the sarcolemma of postnatal human skeletal myofibers. Abnormal expression in merosin-negative and Duchenne muscular dystrophies
-
Petrini S, Tessa A, Carrozzo R, et al. Human melanoma/NG2 chondroitin sulfate proteoglycan is expressed in the sarcolemma of postnatal human skeletal myofibers. Abnormal expression in merosin-negative and Duchenne muscular dystrophies. Mol Cell Neurosci 2003;23:219-231
-
(2003)
Mol Cell Neurosci
, vol.23
, pp. 219-231
-
-
Petrini, S.1
Tessa, A.2
Carrozzo, R.3
-
65
-
-
0025891750
-
Radioimmunodetection of neuroblastoma with iodine-131-3F8: Correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities
-
Yeh SD, Larson SM, Burch L, et al. Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities. J Nucl Med 1991;32:769-776
-
(1991)
J Nucl Med
, vol.32
, pp. 769-776
-
-
Yeh, S.D.1
Larson, S.M.2
Burch, L.3
-
66
-
-
0022399764
-
Eradication of neuroblastoma cells in vitro by monoclonal antibody and human complement: Method for purging autologous bone marrow
-
Saarinen UM, Coccia PF, Gerson SL, et al. Eradication of neuroblastoma cells in vitro by monoclonal antibody and human complement: method for purging autologous bone marrow. Cancer Res 1985;45:5969-5975 (Pubitemid 16218620)
-
(1985)
Cancer Research
, vol.45
, Issue.11 II
, pp. 5969-5975
-
-
Saarinen, U.M.1
Coccia, P.F.2
Gerson, S.L.3
-
67
-
-
0034214210
-
CD59 expressed on a tumor cell surface modulates decay-accelerating factor expression and enhances tumor growth in a rat model of human neuroblastoma
-
Chen S, Caragine T, Cheung NK, Tomlinson S. CD59 expressed on a tumor cell surface modulates decay-accelerating factor expression and enhances tumor growth in a rat model of human neuroblastoma. Cancer Res 2000;60:3013-3018 (Pubitemid 30395828)
-
(2000)
Cancer Research
, vol.60
, Issue.11
, pp. 3013-3018
-
-
Chen, S.1
Caragine, T.2
Cheung, N.-K.V.3
Tomlinson, S.4
-
68
-
-
0026511704
-
Absolute requirement of CD11/CD18 adhesion molecules, FcRII and the phosphatidylinositol-linked FcRIII for monoclonal antibody-mediated neutrophil antihuman tumor cytotoxicity
-
Kushner BH, Cheung NK. Absolute requirement of CD11/CD18 adhesion molecules, FcRII and the phosphatidylinositol-linked FcRIII for monoclonal antibody-mediated neutrophil antihuman tumor cytotoxicity. Blood 1992;79:1484-1490
-
(1992)
Blood
, vol.79
, pp. 1484-1490
-
-
Kushner, B.H.1
Cheung, N.K.2
-
69
-
-
0036625059
-
Antidisialoganglioside/granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcγRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis
-
Metelitsa LS, Gillies SD, Super M, et al. Antidisialoganglioside/ granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcγRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis. Blood 2002;99:4166-4173
-
(2002)
Blood
, vol.99
, pp. 4166-4173
-
-
Metelitsa, L.S.1
Gillies, S.D.2
Super, M.3
-
70
-
-
0033836315
-
2-integrin glycoprotein
-
Ross GD. Regulation of the adhesion versus cytotoxic functions of the Mac-1/CR3/αMβ2-integrin glycoprotein. Crit Rev Immunol 2000;20:197-222 (Pubitemid 30645020)
-
(2000)
Critical Reviews in Immunology
, vol.20
, Issue.3
, pp. 197-222
-
-
Ross, G.D.1
-
71
-
-
67549098774
-
Induction of tumor cell death by anti-GD2 monoclonal antibodies (MoAb): Requirement of antibody Fc and a long residence time (slow koff)
-
2007 ASCO Annual Meeting Proceedings
-
Xu H, Hu J, Cheung NV. Induction of tumor cell death by anti-GD2 monoclonal antibodies (MoAb): Requirement of antibody Fc and a long residence time (slow koff). 2007 ASCO Annual Meeting Proceedings. J Clin Oncol 2007;25(18S):13507
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 S
, pp. 13507
-
-
Xu, H.1
Hu, J.2
Cheung, N.V.3
-
72
-
-
33745528911
-
FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor
-
DOI 10.1200/JCO.2005.04.6011
-
Cheung NK, Sowers R, Vickers AJ, et al. FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor. J Clin Oncol 2006;24:2885-2890 (Pubitemid 46630590)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.18
, pp. 2885-2890
-
-
Cheung, N.-K.V.1
Sowers, R.2
Vickers, A.J.3
Cheung, I.Y.4
Kushner, B.H.5
Gorlick, R.6
-
73
-
-
0023525839
-
Ganglioside G(D2) specific monoclonal antibody 3F8: A phase I study in patients with neuroblastoma and malignant melanoma
-
Cheung NK, Lazarus H, Miraldi FD, et al. Ganglioside GD2 specific monoclonal antibody 3F8: a phase I study in patients with neuroblastoma and malignant melanoma. J Clin Oncol 1987;5:1430-40 •• The first monoclonal antibody study used to assess the toxicity profile of 3F8 in patients with neuroblastoma. (Pubitemid 18049879)
-
(1987)
Journal of Clinical Oncology
, vol.5
, Issue.9
, pp. 1430-1440
-
-
Cheung, N.-K.V.1
Lazarus, H.2
Miraldi, F.D.3
Abramowsky, C.R.4
Kallick, S.5
Saarinen, U.M.6
Spitzer, T.7
Strandjord, S.E.8
Coccia, P.F.9
Berger, N.A.10
-
74
-
-
0032535052
-
Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor
-
Armitage JO. Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor. Blood 1998;92:4491-4508 (Pubitemid 29005850)
-
(1998)
Blood
, vol.92
, Issue.12
, pp. 4491-4508
-
-
Armitage, J.O.1
-
75
-
-
0024358410
-
GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma
-
Kushner BH, Cheung NK. GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma. Blood 1989;73:1936-1941 (Pubitemid 19145127)
-
(1989)
Blood
, vol.73
, Issue.7
, pp. 1936-1941
-
-
Kushner, B.H.1
Cheung, N.-K.V.2
-
76
-
-
0033928328
-
Induction of Ab3 and Ab3' antibody was associated with long-term survival after anti-G(D2) antibody therapy of stage 4 neuroblastoma
-
Cheung NK, Guo HF, Heller G, Cheung IY. Induction of Ab3 and Ab3′ antibody was associated with long-term survival after anti-GD2 antibody therapy of stage 4 neuroblastoma. Clin Cancer Res 2000;6:2653-2660 (Pubitemid 30482100)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.7
, pp. 2653-2660
-
-
Cheung, N.-K.V.1
Guo, H.-F.2
Heller, G.3
Cheung, I.Y.4
-
77
-
-
8544262220
-
131I-monoclonal antibody targeting disialoganglioside in non-human primates
-
DOI 10.1023/A:1005822524905
-
Kramer K, Cheung NK, Humm J, et al. Pharmacokinetics and acute toxicology of intraventricular 131I-monoclonal antibody targeting disialoganglioside in non-human primates. J Neurooncol 1997;35:101-111 (Pubitemid 27361678)
-
(1997)
Journal of Neuro-Oncology
, vol.35
, Issue.2
, pp. 101-111
-
-
Kramer, K.1
Cheung, N.-K.V.2
Humm, J.3
Diresta, G.4
Arbit, E.5
Larson, S.6
Finn, R.7
Rosenblum, M.8
Nguyen, H.9
Gonzalez, G.10
Liu, C.11
Yang, Y.-F.12
Mendelsohn, M.E.13
Gillio, A.P.14
-
78
-
-
36849018928
-
Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8
-
DOI 10.1200/JCO.2007.11.1807
-
Kramer K, Humm JL, Souweidane MM, et al. Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8. J Clin Oncol 2007;25:5465-5470 (Pubitemid 350232224)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.34
, pp. 5465-5470
-
-
Kramer, K.1
Humm, J.L.2
Souweidane, M.M.3
Zanzonico, P.B.4
Dunkel, I.J.5
Gerald, W.L.6
Khakoo, Y.7
Yeh, S.D.8
Yeung, H.W.9
Finn, R.D.10
Wolden, S.L.11
Larson, S.M.12
Cheung, N.-K.V.13
-
79
-
-
4444371613
-
Consolidation treatment with chimeric anti-GD2-Antibody ch14.18 in children older than 1 year with metastatic neuroblastoma
-
DOI 10.1200/JCO.2004.08.143
-
Simon T, Hero B, Faldum A, et al. Consolidation treatment with chimeric anti-GD2-antibody ch14.18 in children older than 1 year with metastatic neuroblastoma. J Clin Oncol 2004;22:3549-3557 (Pubitemid 41103661)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.17
, pp. 3549-3557
-
-
Simon, T.1
Hero, B.2
Faldum, A.3
Handgretinger, R.4
Schrappe, M.5
Niethammer, D.6
Berthold, F.7
-
80
-
-
0034671441
-
D2 monoclonal antibody (ch14.18) with granulocyte-macrophage colony-stimulating factor in children with neuroblastoma immediately after hematopoietic stem-cell transplantation: A Children's Cancer Group study
-
Ozkaynak MF, Sondel PM, Krailo MD, et al. Phase I study of chimeric human/murine anti-ganglioside GD2 monoclonal antibody (ch14.18) with granulocyte-macrophage colony-stimulating factor in children with neuroblastoma immediately after hematopoietic stem-cell transplantation: a Children's Cancer Group Study. J Clin Oncol 2000;18:4077-4085 (Pubitemid 32038400)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.24
, pp. 4077-4085
-
-
Fevzi Ozkaynak, M.1
Sondel, P.M.2
Krailo, M.D.3
Gan, J.4
Javorsky, B.5
Reisfeld, R.A.6
Matthay, K.K.7
Reaman, G.H.8
Seeger, R.C.9
-
81
-
-
33645679838
-
A Phase I clinical trial of the hu14.18-IL2 (EMD 273063) as a treatment for children with refractory or recurrent neuroblastoma and melanoma: A study of the Children's Oncology Group
-
Osenga KL, Hank JA, Albertini MR, et al. A Phase I clinical trial of the hu14.18-IL2 (EMD 273063) as a treatment for children with refractory or recurrent neuroblastoma and melanoma: a study of the Children's Oncology Group. Clin Cancer Res 2006;12:1750-1759
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1750-1759
-
-
Osenga, K.L.1
Hank, J.A.2
Albertini, M.R.3
-
82
-
-
0024386838
-
131I-labeled anti-tenascin monoclonal antibody 81C6 in patients with gliomas and other intracranial malignancies
-
Zalutsky MR, Moseley RP, Coakham HB, et al. Pharmacokinetics and tumor localization of 131I-labeled anti-tenascin monoclonal antibody 81C6 in patients with gliomas and other intracranial malignancies. Cancer Res 1989;49:2807-2813 (Pubitemid 19143420)
-
(1989)
Cancer Research
, vol.49
, Issue.10
, pp. 2807-2813
-
-
Zalutsky, M.R.1
Moseley, R.P.2
Coakham, H.B.3
Coleman, R.E.4
Bigner, D.D.5
-
83
-
-
0029657596
-
131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: Phase I trial results
-
Brown MT, Coleman RE, Friedman AH, et al. Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: Phase I trial results. Clin Cancer Res 1996;2:963-972 (Pubitemid 26199263)
-
(1996)
Clinical Cancer Research
, vol.2
, Issue.6
, pp. 963-972
-
-
Brown, M.T.1
Coleman, R.E.2
Friedman, A.H.3
Friedman, H.S.4
McLendon, R.E.5
Reiman, R.6
Felsberg, G.J.7
Tien, R.D.8
Bigner, S.H.9
Zalutsky, M.R.10
Zhao, X.G.11
Wikstrand, C.J.12
Pegram, C.N.13
Herndon II, J.E.14
Vick, N.A.15
Paleologos, N.16
Fredericks, R.K.17
Schold Jr., S.C.18
Bigner, D.D.19
-
84
-
-
33644833474
-
Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: Phase II study results
-
DOI 10.1200/JCO.2005.03.4082
-
Reardon DA, Akabani G, Coleman RE, et al. Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: Phase II study results. J Clin Oncol 2006;24:115-122 (Pubitemid 46630502)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 115-122
-
-
Reardon, D.A.1
Akabani, G.2
Coleman, R.E.3
Friedman, A.H.4
Friedman, H.S.5
Herndon II, J.E.6
McLendon, R.E.7
Pegram, C.N.8
Provenzale, J.M.9
Quinn, J.A.10
Rich, J.N.11
Vredenburgh, J.J.12
Desjardins, A.13
Guruangan, S.14
Badruddoja, M.15
Dowell, J.M.16
Wong, T.Z.17
Zhao, X.-G.18
Zalutsky, M.R.19
Bigner, D.D.20
more..
-
85
-
-
0036498790
-
131I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas
-
DOI 10.1200/JCO.20.5.1389
-
Reardon DA, Akabani G, Coleman RE, et al. Phase II trial of murine 131I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. J Clin Oncol 2002;20:1389-1397 (Pubitemid 34177447)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.5
, pp. 1389-1397
-
-
Reardon, D.A.1
Akabani, G.2
Coleman, R.E.3
Friedman, A.H.4
Friedman, H.S.5
Herndon II, J.E.6
Cokgor, I.7
McLendon, R.E.8
Pegram, C.N.9
Provenzale, J.M.10
Quinn, J.A.11
Rich, J.N.12
Regalado, L.V.13
Sampson, J.H.14
Shafman, T.D.15
Wikstrand, C.J.16
Wong, T.Z.17
Zhao, X.-G.18
Zalutsky, M.R.19
Bigner, D.D.20
more..
-
86
-
-
44849110617
-
A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost
-
Reardon DA, Zalutsky MR, Akabani G, et al. A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost. Neuro Oncol 2008;10:182-189
-
(2008)
Neuro Oncol
, vol.10
, pp. 182-189
-
-
Reardon, D.A.1
Zalutsky, M.R.2
Akabani, G.3
-
87
-
-
33746059453
-
131I and administered into the surgically created resection cavity of patients with malignant glioma: Phase I trial results
-
Reardon DA, Quinn JA, Akabani G, et al. Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant glioma: phase I trial results. J Nucl Med 2006;47:912-918 (Pubitemid 46939942)
-
(2006)
Journal of Nuclear Medicine
, vol.47
, Issue.6
, pp. 912-918
-
-
Reardon, D.A.1
Quinn, J.A.2
Akabani, G.3
Coleman, R.E.4
Friedman, A.H.5
Friedman, H.S.6
Herndon II, J.E.7
McLendon, R.E.8
Pegram, C.N.9
Provenzale, J.M.10
Dowell, J.M.11
Rich, J.N.12
Vredenburgh, J.J.13
Desjardins, A.14
Sampson, J.H.15
Gururangan, S.16
Wong, T.Z.17
Badruddoja, M.A.18
Zhao, X.-G.19
Bigner, D.D.20
Zalutsky, M.R.21
more..
-
88
-
-
37649010802
-
Clinical experience with α-particle emitting 211At: Treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6
-
Zalutsky MR, Reardon DA, Akabani G, et al. Clinical experience with α-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6. J Nucl Med 2008;49:30-38
-
(2008)
J Nucl Med
, vol.49
, pp. 30-38
-
-
Zalutsky, M.R.1
Reardon, D.A.2
Akabani, G.3
-
89
-
-
31144463014
-
Intralesional targeted alpha therapy for metastatic melanoma
-
Allen BJ, Raja C, Rizvi S, et al. Intralesional targeted alpha therapy for metastatic melanoma. Cancer Biol Ther 2005;4:1318-1324 (Pubitemid 43131174)
-
(2005)
Cancer Biology and Therapy
, vol.4
, Issue.12
, pp. 1318-1324
-
-
Allen, B.J.1
Raja, C.2
Rizvi, S.3
Li, Y.4
Tsui, W.5
Graham, P.6
Thompson, J.F.7
Reisfeld, R.A.8
Kearsley, J.9
-
90
-
-
38049170147
-
Interim analysis of toxicity and response in phase 1 trial of systemic targeted alpha therapy for metastatic melanoma
-
Raja C, Graham P, Abbas Rizvi SM, et al. Interim analysis of toxicity and response in Phase 1 trial of systemic targeted alpha therapy for metastatic melanoma. Cancer Biol Ther 2007;6:846-852 (Pubitemid 351574972)
-
(2007)
Cancer Biology and Therapy
, vol.6
, Issue.6
, pp. 846-852
-
-
Raja, C.1
Graham, P.2
Abbas Rizvi, S.M.3
Song, E.4
Goldsmith, H.5
Thompson, J.6
Bosserhoff, A.7
Morgenstern, A.8
Apostolidis, C.9
Kearsley, J.10
Reisfeld, R.11
Allen, B.J.12
-
91
-
-
0025945894
-
Fc receptors and immunoglobulin binding factors
-
Fridman WH. Fc receptors and immunoglobulin binding factors. FASEB J 1991;5:2684-2690 (Pubitemid 21905820)
-
(1991)
FASEB Journal
, vol.5
, Issue.12
, pp. 2684-2690
-
-
Fridman, W.H.1
-
93
-
-
35648978158
-
Structure-function relationships of the variable domains of monoclonal antibodies approved for cancer treatment
-
A recent study attempting to identify structural attributes common among FDA approved antibodies
-
Magdelaine-Beuzelin C, Kaas Q, Wehbi V, et al. Structure-function relationships of the variable domains of monoclonal antibodies approved for cancer treatment. Crit Rev Oncol Hematol 2007;64:210-25 • A recent study attempting to identify structural attributes common among FDA approved antibodies.
-
(2007)
Crit Rev Oncol Hematol
, vol.64
, pp. 210-225
-
-
Magdelaine-Beuzelin, C.1
Kaas, Q.2
Wehbi, V.3
-
94
-
-
0026684815
-
Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
-
Yokota T, Milenic DE, Whitlow M, Schlom J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res 1992;52:3402-3408
-
(1992)
Cancer Res
, vol.52
, pp. 3402-3408
-
-
Yokota, T.1
Milenic, D.E.2
Whitlow, M.3
Schlom, J.4
-
95
-
-
33644659256
-
Principles and use of anti-CTLA4 antibody in human cancer immunotherapy
-
DOI 10.1016/j.coi.2006.01.011, PII S0952791506000148, Lymphocyte Development / Tumor Immunology
-
Peggs KS, Quezada SA, Korman AJ, Allison JP. Principles and use of anti-CTLA4 antibody in human cancer immunotherapy. Curr Opin Immunol 2006;18:206-213 (Pubitemid 43327304)
-
(2006)
Current Opinion in Immunology
, vol.18
, Issue.2
, pp. 206-213
-
-
Peggs, K.S.1
Quezada, S.A.2
Korman, A.J.3
Allison, J.P.4
-
96
-
-
36849055007
-
Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2-overexpressing breast cancer: A phase I dose-escalation study
-
DOI 10.1200/JCO.2007.11.7960
-
Modi S, Stopeck AT, Gordon MS, et al. Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: a phase I dose-escalation study. J Clin Oncol 2007;25:5410-5417 (Pubitemid 350232217)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.34
, pp. 5410-5417
-
-
Modi, S.1
Stopeck, A.T.2
Gordon, M.S.3
Mendelson, D.4
Solit, D.B.5
Bagatell, R.6
Ma, W.7
Wheler, J.8
Rosen, N.9
Norton, L.10
Cropp, G.F.11
Johnson, R.G.12
Hannah, A.L.13
Hudis, C.A.14
-
97
-
-
34250363163
-
Tumour anti-vascular alpha therapy: A mechanism for the regression of solid tumours in metastatic cancer
-
DOI 10.1088/0031-9155/52/13/L01, PII S0031915507455567, L01
-
Allen BJ, Raja C, Rizvi S, et al. Tumour anti-vascular alpha therapy: a mechanism for the regression of solid tumours in metastatic cancer. Phys Med Biol 2007;52:L15-9 (Pubitemid 46908610)
-
(2007)
Physics in Medicine and Biology
, vol.52
, Issue.13
-
-
Allen, B.J.1
Raja, C.2
Rizvi, S.3
Song, E.Y.4
Graham, P.5
|