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Volumn 9, Issue 3, 2009, Pages 341-353

Monoclonal antibody therapies for solid tumors

Author keywords

Antibody conjugates; FDA approved; Immunotherapy; Investigational; Radioimmunotherapy

Indexed keywords

81C 6; 9 2 27; ALPHA2A INTERFERON; BEVACIZUMAB; CARBOPLATIN; CETUXIMAB; CISPLATIN; CP 751 871; ERTUMAXOMAB; FLUOROPYRIMIDINE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; HUJ 751; HUMV 833; HUMV 833 ANTIBODY; IMCL 1121B; IMCL 1121B ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G4; IPILIMUMAB; IRINOTECAN; LEXATUMUMAB; MAPATUMUMAB; MATUZUMAB; MLN 2704; MONOCLONAL ANTIBODY; NAVELBINE; OXALIPLATIN; PACLITAXEL; PANITUMUMAB; PERTUZUMAB; PLATINUM DERIVATIVE; R 1507; TICILIMUMAB; TRASTUZUMAB; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZALUTUMUMAB; ANTINEOPLASTIC AGENT;

EID: 65549152525     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712590802715764     Document Type: Review
Times cited : (22)

References (97)
  • 1
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975;256:495-497
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 2
    • 42949106166 scopus 로고    scopus 로고
    • Monoclonal antibodies in cancer therapy: 25 Years of progress
    • A review detailing the field of monoclonal antibody therapies in the past 25 years
    • Oldham RK, Dillman RO. Monoclonal antibodies in cancer therapy: 25 years of progress. J Clin Oncol 2008;26:1774-7 • A review detailing the field of monoclonal antibody therapies in the past 25 years.
    • (2008) J Clin Oncol , vol.26 , pp. 1774-1777
    • Oldham, R.K.1    Dillman, R.O.2
  • 4
    • 45149122101 scopus 로고    scopus 로고
    • Newer monoclonal antibodies for hematological malignancies
    • DOI 10.1016/j.exphem.2008.04.018, PII S0301472X08002075
    • Castillo J, Winer E, Quesenberry P. Newer monoclonal antibodies for hematological malignancies. Exp Hematol 2008;36:755-768 (Pubitemid 351826873)
    • (2008) Experimental Hematology , vol.36 , Issue.7 , pp. 755-768
    • Castillo, J.1    Winer, E.2    Quesenberry, P.3
  • 5
    • 48049118634 scopus 로고    scopus 로고
    • Approved monoclonal antibodies for cancer therapy
    • Boyiadzis M, Foon KA. Approved monoclonal antibodies for cancer therapy. Expert Opin Biol Ther 2008;8:1151-1158
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 1151-1158
    • Boyiadzis, M.1    Foon, K.A.2
  • 6
    • 39749096242 scopus 로고    scopus 로고
    • VEGF polymorphisms and survival in early-stage non-small-cell lung cancer
    • Heist RS, Zhai R, Liu G, et al. VEGF polymorphisms and survival in early-stage non-small-cell lung cancer. J Clin Oncol 2008;26:856-862
    • (2008) J Clin Oncol , vol.26 , pp. 856-862
    • Heist, R.S.1    Zhai, R.2    Liu, G.3
  • 7
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Study leading to the first FDA approval of Bevacizumab
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-42 •• Study leading to the first FDA approval of Bevacizumab.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 8
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • DOI 10.1200/JCO.2006.09.6305
    • Giantonio BJ, Catalano PJ, Meropol N, et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 2007;25:1539-1544 (Pubitemid 46733080)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.12 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3    O'Dwyer, P.J.4    Mitchell, E.P.5    Alberts, S.R.6    Schwartz, M.A.7    Benson III, A.B.8
  • 10
    • 45849133426 scopus 로고    scopus 로고
    • Bevacizumab for the treatment of advanced non-small-cell lung cancer
    • Manegold C. Bevacizumab for the treatment of advanced non-small-cell lung cancer. Expert Rev Anticancer Ther 2008;8:689-699
    • (2008) Expert Rev Anticancer Ther , vol.8 , pp. 689-699
    • Manegold, C.1
  • 12
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007;357:2666-2676
    • (2007) N Engl J Med , vol.357 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3
  • 13
    • 42049112958 scopus 로고    scopus 로고
    • Correlation between rash and a positive drug response associated with bevacizumab in a patient with advanced colorectal cancer
    • Saif MW, Longo WL, Israel G. Correlation between rash and a positive drug response associated with bevacizumab in a patient with advanced colorectal cancer. Clin Colorectal Cancer 2008;7:144-148
    • (2008) Clin Colorectal Cancer , vol.7 , pp. 144-148
    • Saif, M.W.1    Longo, W.L.2    Israel, G.3
  • 15
    • 49249113484 scopus 로고    scopus 로고
    • Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity
    • Azad NS, Posadas EM, Kwitkowski VE, et al. Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. J Clin Oncol 2008;26:3709-3714
    • (2008) J Clin Oncol , vol.26 , pp. 3709-3714
    • Azad, N.S.1    Posadas, E.M.2    Kwitkowski, V.E.3
  • 16
    • 52949097293 scopus 로고    scopus 로고
    • Bevacizumab: A treatment option for recurrent glioblastoma multiforme
    • Buie LW, Valgus J. Bevacizumab: a treatment option for recurrent glioblastoma multiforme. Ann Pharmacother 2008;42:1486-1490
    • (2008) Ann Pharmacother , vol.42 , pp. 1486-1490
    • Buie, L.W.1    Valgus, J.2
  • 17
    • 46449091500 scopus 로고    scopus 로고
    • Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma
    • Siegel AB, Cohen EI, Ocean A, et al. Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma. J Clin Oncol 2008;26:2992-2998
    • (2008) J Clin Oncol , vol.26 , pp. 2992-2998
    • Siegel, A.B.1    Cohen, E.I.2    Ocean, A.3
  • 18
    • 84969305913 scopus 로고    scopus 로고
    • HER2 genetic polymorphism and pharmacodynamics of trastuzumab-based treatment in breast cancer patients
    • ASCO Annual Meeting Proceedings
    • Milano GA, Lescault W, Formento JL, et al. HER2 genetic polymorphism and pharmacodynamics of trastuzumab-based treatment in breast cancer patients. ASCO Annual Meeting Proceedings. J Clin Oncol 2005;23(16S):501
    • (2005) J Clin Oncol , vol.23 , Issue.16 S , pp. 501
    • Milano, G.A.1    Lescault, W.2    Formento, J.L.3
  • 19
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh MA, Vogel CL, Tripathy D, et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999;17:2639-48 •• Study leading to the first FDA approval of Trastuzumab. (Pubitemid 29415219)
    • (1999) Journal of Clinical Oncology , vol.17 , Issue.9 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3    Robert, N.J.4    Scholl, S.5    Fehrenbacher, L.6    Wolter, J.M.7    Paton, V.8    Shak, S.9    Lieberman, G.10    Slamon, D.J.11
  • 21
    • 34948815141 scopus 로고    scopus 로고
    • Benefit from adjuvant trastuzumab may not be confined to patients with IHC 3+ and/or FISH-positive tumors: Central testing results from NSABP B-31
    • ASCO Annual Meeting Proceedings. A recent analysis suggesting that the use of trastuzumab may not be confined strictly to HER2-amplified tumors
    • Paik S, Kim C, Jeong J, et al. Benefit from adjuvant trastuzumab may not be confined to patients with IHC 3+ and/or FISH-positive tumors: Central testing results from NSABP B-31. ASCO Annual Meeting Proceedings. J Clin Oncol 2007;25(18S):511 • A recent analysis suggesting that the use of trastuzumab may not be confined strictly to HER2-amplified tumors.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S , pp. 511
    • Paik, S.1    Kim, C.2    Jeong, J.3
  • 23
    • 53149143875 scopus 로고    scopus 로고
    • Advanced bladder cancer: Status of first-line chemotherapy and the search for active agents in the second-line setting
    • Gallagher DJ, Milowsky MI, Bajorin DF. Advanced bladder cancer: status of first-line chemotherapy and the search for active agents in the second-line setting. Cancer 2008;113:1284-1293
    • (2008) Cancer , vol.113 , pp. 1284-1293
    • Gallagher, D.J.1    Milowsky, M.I.2    Bajorin, D.F.3
  • 24
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • Two trials leading to FDA approval of Cetuximab for head and neck cancer
    • Bonner JA, Harari PM, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006;354:567-78 •• Two trials leading to FDA approval of Cetuximab for head and neck cancer.
    • (2006) N Engl J Med , vol.354 , pp. 567-578
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3
  • 25
    • 34250180582 scopus 로고    scopus 로고
    • Open-label, uncontrolled, multicenter phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy
    • DOI 10.1200/JCO.2006.06.7447
    • Vermorken JB, Trigo J, Hitt R, et al. Open-label, uncontrolled, multicenter Phase II study to evaluate the efficacy and toxicity of cetuximab as a single agent in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck who failed to respond to platinum-based therapy. J Clin Oncol 2007;25:2171-7 •• Two trials leading to FDA approval of Cetuximab for head and neck cancer. (Pubitemid 46954639)
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.16 , pp. 2171-2177
    • Vermorken, J.B.1    Trigo, J.2    Hitt, R.3    Koralewski, P.4    Diaz-Rubio, E.5    Rolland, F.6    Knecht, R.7    Amellal, N.8    Schueler, A.9    Baselga, J.10
  • 27
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • DOI 10.1200/JCO.2004.10.182
    • Saltz LB, Meropol NJ, Loehrer PJ Sr, et al. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 2004;22:1201-1208 (Pubitemid 41079832)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.7 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer Sr., P.J.3    Needle, M.N.4    Kopit, J.5    Mayer, R.J.6
  • 28
    • 36049003128 scopus 로고    scopus 로고
    • Current Immunotherapeutic Strategies in Pancreatic Cancer
    • DOI 10.1016/j.soc.2007.07.012, PII S1055320707000944, Tumor Immunology for the Practicing Surgeon
    • Plate JM. Current immunotherapeutic strategies in pancreatic cancer. Surg Oncol Clin N Am 2007;16:919-43, xi (Pubitemid 350101277)
    • (2007) Surgical Oncology Clinics of North America , vol.16 , Issue.4 , pp. 919-943
    • Plate, J.M.D.1
  • 30
    • 37649022615 scopus 로고    scopus 로고
    • Randomized Phase II study of gemcitabine plus cisplatin or carboplatin [corrected], with or without cetuximab, as first-line therapy for patients with advanced or metastatic non small-cell lung cancer
    • Erratum in J Clin Oncol 2008;26(19):3295
    • Butts CA, Bodkin D, Middleman EL, et al. Randomized Phase II study of gemcitabine plus cisplatin or carboplatin [corrected], with or without cetuximab, as first-line therapy for patients with advanced or metastatic non small-cell lung cancer. J Clin Oncol 2007;25:5777-84. Erratum in J Clin Oncol 2008;26(19):3295
    • (2007) J Clin Oncol , vol.25 , pp. 5777-5784
    • Butts, C.A.1    Bodkin, D.2    Middleman, E.L.3
  • 31
    • 34547866682 scopus 로고    scopus 로고
    • Targeting EGFR and HER-2 with cetuximab- And trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma
    • DOI 10.1038/sj.bjc.6603885, PII 6603885
    • Kawaguchi Y, Kono K, Mimura K, et al. Targeting EGFR and HER-2 with cetuximab- and trastuzumab-mediated immunotherapy in oesophageal squamous cell carcinoma. Br J Cancer 2007;97:494-501 (Pubitemid 47258449)
    • (2007) British Journal of Cancer , vol.97 , Issue.4 , pp. 494-501
    • Kawaguchi, Y.1    Kono, K.2    Mimura, K.3    Mitsui, F.4    Sugai, H.5    Akaike, H.6    Fujii, H.7
  • 33
    • 51649085865 scopus 로고    scopus 로고
    • Platinum-based chemotherapy plus cetuximab in head and neck cancer
    • Vermorken JB, Mesia R, Rivera F, et al. Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 2008;359:1116-1127
    • (2008) N Engl J Med , vol.359 , pp. 1116-1127
    • Vermorken, J.B.1    Mesia, R.2    Rivera, F.3
  • 35
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:1626-1634
    • (2008) J Clin Oncol , vol.26 , pp. 1626-1634
    • Amado, R.G.1    Wolf, M.2    Peeters, M.3
  • 37
    • 34547697317 scopus 로고    scopus 로고
    • Antibodies to the epidermal growth factor receptor in non-small cell lung cancer: Current status of matuzumab and panitumumab
    • DOI 10.1158/1078-0432.CCR-07-0335
    • Socinski MA. Antibodies to the epidermal growth factor receptor in non small cell lung cancer: current status of matuzumab and panitumumab. Clin Cancer Res 2007;13:s4597-601 (Pubitemid 47219731)
    • (2007) Clinical Cancer Research , vol.13 , Issue.15
    • Socinski, M.A.1
  • 38
    • 49449119098 scopus 로고    scopus 로고
    • Antibody-drug conjugates for cancer therapy
    • Carter PJ, Senter PD. Antibody-drug conjugates for cancer therapy. Cancer J 2008;14:154-169
    • (2008) Cancer J , vol.14 , pp. 154-169
    • Carter, P.J.1    Senter, P.D.2
  • 39
    • 54049137660 scopus 로고    scopus 로고
    • Clinical trials of targeted alpha therapy for cancer
    • Allen BJ. Clinical trials of targeted alpha therapy for cancer. Rev Recent Clin Trials 2008;3:185-191
    • (2008) Rev Recent Clin Trials , vol.3 , pp. 185-191
    • Allen, B.J.1
  • 40
    • 17644418758 scopus 로고    scopus 로고
    • Radioimmunodetection and therapy of breast cancer
    • DeNardo SJ. Radioimmunodetection and therapy of breast cancer. Semin Nucl Med 2005;35:143-151
    • (2005) Semin Nucl Med , vol.35 , pp. 143-151
    • Denardo, S.J.1
  • 41
    • 52649150833 scopus 로고    scopus 로고
    • Targeting angiogenesis driven by vascular endothelial growth factors using antibody-based therapies
    • Grothey A, Ellis LM. Targeting angiogenesis driven by vascular endothelial growth factors using antibody-based therapies. Cancer J 2008;14:170-177
    • (2008) Cancer J , vol.14 , pp. 170-177
    • Grothey, A.1    Ellis, L.M.2
  • 47
    • 33646870539 scopus 로고    scopus 로고
    • A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC)
    • Kollmannsberger C, Schittenhelm M, Honecker F, et al. A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC). Ann Oncol 2006;17:1007-1013
    • (2006) Ann Oncol , vol.17 , pp. 1007-1013
    • Kollmannsberger, C.1    Schittenhelm, M.2    Honecker, F.3
  • 48
    • 33646504884 scopus 로고    scopus 로고
    • Phase I study of the humanised anti-EGFR monoclonal antibody matuzumab (EMD 72000) combined with gemcitabine in advanced pancreatic cancer
    • Graeven U, Kremer B, Sudhoff T, et al. Phase I study of the humanised anti-EGFR monoclonal antibody matuzumab (EMD 72000) combined with gemcitabine in advanced pancreatic cancer. Br J Cancer 2006;94:1293-1299
    • (2006) Br J Cancer , vol.94 , pp. 1293-1299
    • Graeven, U.1    Kremer, B.2    Sudhoff, T.3
  • 49
    • 33846950834 scopus 로고    scopus 로고
    • A phase II trial of EMD72000 (matuzumab), a humanized anti-EGFR monoclonal antibody, in patients with platinum-resistant ovarian and primary peritoneal malignancies
    • DOI 10.1016/j.ygyno.2006.10.019, PII S0090825806008092
    • Seiden MV, Burris HA, Matulonis U, et al. A phase II trial of EMD72000 (matuzumab), a humanized anti-EGFR monoclonal antibody, in patients with platinum-resistant ovarian and primary peritoneal malignancies. Gynecol Oncol 2007;104:727-731 (Pubitemid 46251417)
    • (2007) Gynecologic Oncology , vol.104 , Issue.3 , pp. 727-731
    • Seiden, M.V.1    Burris, H.A.2    Matulonis, U.3    Hall, J.B.4    Armstrong, D.K.5    Speyer, J.6    Weber, J.D.A.7    Muggia, F.8
  • 50
    • 37549036341 scopus 로고    scopus 로고
    • Current situation of Panitumumab, Matuzumab, Nimotuzumab and Zalutumumab
    • Rivera F, Vega-Villegas ME, Lopez-Brea MF, Marquez R. Current situation of Panitumumab, Matuzumab, Nimotuzumab and Zalutumumab. Acta Oncol 2008;47:9-19
    • (2008) Acta Oncol , vol.47 , pp. 9-19
    • Rivera, F.1    Vega-Villegas, M.E.2    Lopez-Brea, M.F.3    Marquez, R.4
  • 51
    • 0035872404 scopus 로고    scopus 로고
    • Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors
    • Modak S, Kramer K, Gultekin SH, et al. Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors. Cancer Res 2001;61:4048-4054 (Pubitemid 32720969)
    • (2001) Cancer Research , vol.61 , Issue.10 , pp. 4048-4054
    • Modak, S.1    Kramer, K.2    Gultekin, S.H.3    Guo, H.F.4    Cheung, N.-K.V.5
  • 52
    • 34548257760 scopus 로고    scopus 로고
    • Review: Anti-CTLA-4 antibody ipilimumab: Case studies of clinical response and immune-related adverse events
    • DOI 10.1634/theoncologist.12-7-864
    • Weber J. Review: anti-CTLA-4 antibody ipilimumab: case studies of clinical response and immune-related adverse events. Oncologist 2007;12:864-872 (Pubitemid 47328229)
    • (2007) Oncologist , vol.12 , Issue.7 , pp. 864-872
    • Weber, J.1
  • 54
    • 54349094280 scopus 로고    scopus 로고
    • Tremelimumab (CP-675,206): A fully human anticytotoxic T lymphocyte-associated antigen 4 monoclonal antibody for treatment of patients with advanced cancers
    • Tarhini AA, Kirkwood JM. Tremelimumab (CP-675,206): a fully human anticytotoxic T lymphocyte-associated antigen 4 monoclonal antibody for treatment of patients with advanced cancers. Expert Opin Biol Ther 2008;8:1583-1593
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 1583-1593
    • Tarhini, A.A.1    Kirkwood, J.M.2
  • 55
    • 55949137090 scopus 로고    scopus 로고
    • Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma
    • [abstract LBA9011]. ASCO Annual Meeting Proceedings. Phase III trial in which Tremelimumab failed to show an improvement in OS versus chemotherapy alone in metastatic melanoma
    • Ribas A, Hauschild A, Kefford R, et al. Phase III, open-label, randomized, comparative study of tremelimumab (CP-675,206) and chemotherapy (temozolomide [TMZ] or dacarbazine [DTIC]) in patients with advanced melanoma [abstract LBA9011]. ASCO Annual Meeting Proceedings. J Clin Oncol 2008;26(suppl) •• Phase III trial in which Tremelimumab failed to show an improvement in OS versus chemotherapy alone in metastatic melanoma.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL.
    • Ribas, A.1    Hauschild, A.2    Kefford, R.3
  • 57
    • 50349092260 scopus 로고    scopus 로고
    • A Phase 1 study of mapatumumab (fully human monoclonal antibody to TRAIL-R1) in patients with advanced solid malignancies
    • Hotte SJ, Hirte HW, Chen EX, et al. A Phase 1 study of mapatumumab (fully human monoclonal antibody to TRAIL-R1) in patients with advanced solid malignancies. Clin Cancer Res 2008;14:3450-3455
    • (2008) Clin Cancer Res , vol.14 , pp. 3450-3455
    • Hotte, S.J.1    Hirte, H.W.2    Chen, E.X.3
  • 58
    • 45649084324 scopus 로고    scopus 로고
    • Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer
    • Greco FA, Bonomi P, Crawford J, et al. Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer. Lung Cancer 2008;61:82-90
    • (2008) Lung Cancer , vol.61 , pp. 82-90
    • Greco, F.A.1    Bonomi, P.2    Crawford, J.3
  • 59
    • 4344618391 scopus 로고    scopus 로고
    • Phase I trial of yttrium-90-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for androgen-independent prostate cancer
    • DOI 10.1200/JCO.2004.09.154
    • Milowsky MI, Nanus DM, Kostakoglu L, et al. Phase I trial of yttrium-90-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for androgen-independent prostate cancer. J Clin Oncol 2004;22:2522-2531 (Pubitemid 41103739)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.13 , pp. 2522-2531
    • Milowsky, M.I.1    Nanus, D.M.2    Kostakoglu, L.3    Vallabhajosula, S.4    Goldsmith, S.J.5    Bander, N.H.6
  • 60
    • 22044451179 scopus 로고    scopus 로고
    • 177Lutetium-labeled J591, a monoclonal antibody to prostate-specific membrane antigen, in patients with androgen-independent prostate cancer
    • DOI 10.1200/JCO.2005.05.160
    • Bander NH, Milowsky MI, Nanus DM, et al. Phase I trial of 177lutetium-labeled J591, a monoclonal antibody to prostate-specific membrane antigen, in patients with androgen-independent prostate cancer. J Clin Oncol 2005;23:4591-4601 (Pubitemid 46224061)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.21 , pp. 4591-4601
    • Bander, N.H.1    Milowsky, M.I.2    Nanus, D.M.3    Kostakoglu, L.4    Vallabhajosula, S.5    Goldsmith, S.J.6
  • 61
    • 43749092340 scopus 로고    scopus 로고
    • Phase I trial of the prostate-specific membrane antigen-directed immunoconjugate MLN2704 in patients with progressive metastatic castration-resistant prostate cancer
    • Galsky MD, Eisenberger M, Moore-Cooper S, et al. Phase I trial of the prostate-specific membrane antigen-directed immunoconjugate MLN2704 in patients with progressive metastatic castration-resistant prostate cancer. J Clin Oncol 2008;26:2147-2154
    • (2008) J Clin Oncol , vol.26 , pp. 2147-2154
    • Galsky, M.D.1    Eisenberger, M.2    Moore-Cooper, S.3
  • 62
    • 36148981957 scopus 로고    scopus 로고
    • A Phase I study of q3W R1507, a human monoclonal antibody IGF-1R antagonist in patients with advanced cancer
    • Rodon J, Patnaik A, Stein M, et al. A Phase I study of q3W R1507, a human monoclonal antibody IGF-1R antagonist in patients with advanced cancer. ASCO Meeting Abstracts 2007;25:3590
    • (2007) ASCO Meeting Abstracts , vol.25 , pp. 3590
    • Rodon, J.1    Patnaik, A.2    Stein, M.3
  • 64
    • 0038383042 scopus 로고    scopus 로고
    • Human melanoma/NG2 chondroitin sulfate proteoglycan is expressed in the sarcolemma of postnatal human skeletal myofibers. Abnormal expression in merosin-negative and Duchenne muscular dystrophies
    • Petrini S, Tessa A, Carrozzo R, et al. Human melanoma/NG2 chondroitin sulfate proteoglycan is expressed in the sarcolemma of postnatal human skeletal myofibers. Abnormal expression in merosin-negative and Duchenne muscular dystrophies. Mol Cell Neurosci 2003;23:219-231
    • (2003) Mol Cell Neurosci , vol.23 , pp. 219-231
    • Petrini, S.1    Tessa, A.2    Carrozzo, R.3
  • 65
    • 0025891750 scopus 로고
    • Radioimmunodetection of neuroblastoma with iodine-131-3F8: Correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities
    • Yeh SD, Larson SM, Burch L, et al. Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities. J Nucl Med 1991;32:769-776
    • (1991) J Nucl Med , vol.32 , pp. 769-776
    • Yeh, S.D.1    Larson, S.M.2    Burch, L.3
  • 66
    • 0022399764 scopus 로고
    • Eradication of neuroblastoma cells in vitro by monoclonal antibody and human complement: Method for purging autologous bone marrow
    • Saarinen UM, Coccia PF, Gerson SL, et al. Eradication of neuroblastoma cells in vitro by monoclonal antibody and human complement: method for purging autologous bone marrow. Cancer Res 1985;45:5969-5975 (Pubitemid 16218620)
    • (1985) Cancer Research , vol.45 , Issue.11 II , pp. 5969-5975
    • Saarinen, U.M.1    Coccia, P.F.2    Gerson, S.L.3
  • 67
    • 0034214210 scopus 로고    scopus 로고
    • CD59 expressed on a tumor cell surface modulates decay-accelerating factor expression and enhances tumor growth in a rat model of human neuroblastoma
    • Chen S, Caragine T, Cheung NK, Tomlinson S. CD59 expressed on a tumor cell surface modulates decay-accelerating factor expression and enhances tumor growth in a rat model of human neuroblastoma. Cancer Res 2000;60:3013-3018 (Pubitemid 30395828)
    • (2000) Cancer Research , vol.60 , Issue.11 , pp. 3013-3018
    • Chen, S.1    Caragine, T.2    Cheung, N.-K.V.3    Tomlinson, S.4
  • 68
    • 0026511704 scopus 로고
    • Absolute requirement of CD11/CD18 adhesion molecules, FcRII and the phosphatidylinositol-linked FcRIII for monoclonal antibody-mediated neutrophil antihuman tumor cytotoxicity
    • Kushner BH, Cheung NK. Absolute requirement of CD11/CD18 adhesion molecules, FcRII and the phosphatidylinositol-linked FcRIII for monoclonal antibody-mediated neutrophil antihuman tumor cytotoxicity. Blood 1992;79:1484-1490
    • (1992) Blood , vol.79 , pp. 1484-1490
    • Kushner, B.H.1    Cheung, N.K.2
  • 69
    • 0036625059 scopus 로고    scopus 로고
    • Antidisialoganglioside/granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcγRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis
    • Metelitsa LS, Gillies SD, Super M, et al. Antidisialoganglioside/ granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcγRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis. Blood 2002;99:4166-4173
    • (2002) Blood , vol.99 , pp. 4166-4173
    • Metelitsa, L.S.1    Gillies, S.D.2    Super, M.3
  • 70
    • 0033836315 scopus 로고    scopus 로고
    • 2-integrin glycoprotein
    • Ross GD. Regulation of the adhesion versus cytotoxic functions of the Mac-1/CR3/αMβ2-integrin glycoprotein. Crit Rev Immunol 2000;20:197-222 (Pubitemid 30645020)
    • (2000) Critical Reviews in Immunology , vol.20 , Issue.3 , pp. 197-222
    • Ross, G.D.1
  • 71
    • 67549098774 scopus 로고    scopus 로고
    • Induction of tumor cell death by anti-GD2 monoclonal antibodies (MoAb): Requirement of antibody Fc and a long residence time (slow koff)
    • 2007 ASCO Annual Meeting Proceedings
    • Xu H, Hu J, Cheung NV. Induction of tumor cell death by anti-GD2 monoclonal antibodies (MoAb): Requirement of antibody Fc and a long residence time (slow koff). 2007 ASCO Annual Meeting Proceedings. J Clin Oncol 2007;25(18S):13507
    • (2007) J Clin Oncol , vol.25 , Issue.18 S , pp. 13507
    • Xu, H.1    Hu, J.2    Cheung, N.V.3
  • 72
    • 33745528911 scopus 로고    scopus 로고
    • FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor
    • DOI 10.1200/JCO.2005.04.6011
    • Cheung NK, Sowers R, Vickers AJ, et al. FCGR2A polymorphism is correlated with clinical outcome after immunotherapy of neuroblastoma with anti-GD2 antibody and granulocyte macrophage colony-stimulating factor. J Clin Oncol 2006;24:2885-2890 (Pubitemid 46630590)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.18 , pp. 2885-2890
    • Cheung, N.-K.V.1    Sowers, R.2    Vickers, A.J.3    Cheung, I.Y.4    Kushner, B.H.5    Gorlick, R.6
  • 74
    • 0032535052 scopus 로고    scopus 로고
    • Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor
    • Armitage JO. Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor. Blood 1998;92:4491-4508 (Pubitemid 29005850)
    • (1998) Blood , vol.92 , Issue.12 , pp. 4491-4508
    • Armitage, J.O.1
  • 75
    • 0024358410 scopus 로고
    • GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma
    • Kushner BH, Cheung NK. GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma. Blood 1989;73:1936-1941 (Pubitemid 19145127)
    • (1989) Blood , vol.73 , Issue.7 , pp. 1936-1941
    • Kushner, B.H.1    Cheung, N.-K.V.2
  • 76
    • 0033928328 scopus 로고    scopus 로고
    • Induction of Ab3 and Ab3' antibody was associated with long-term survival after anti-G(D2) antibody therapy of stage 4 neuroblastoma
    • Cheung NK, Guo HF, Heller G, Cheung IY. Induction of Ab3 and Ab3′ antibody was associated with long-term survival after anti-GD2 antibody therapy of stage 4 neuroblastoma. Clin Cancer Res 2000;6:2653-2660 (Pubitemid 30482100)
    • (2000) Clinical Cancer Research , vol.6 , Issue.7 , pp. 2653-2660
    • Cheung, N.-K.V.1    Guo, H.-F.2    Heller, G.3    Cheung, I.Y.4
  • 80
    • 0034671441 scopus 로고    scopus 로고
    • D2 monoclonal antibody (ch14.18) with granulocyte-macrophage colony-stimulating factor in children with neuroblastoma immediately after hematopoietic stem-cell transplantation: A Children's Cancer Group study
    • Ozkaynak MF, Sondel PM, Krailo MD, et al. Phase I study of chimeric human/murine anti-ganglioside GD2 monoclonal antibody (ch14.18) with granulocyte-macrophage colony-stimulating factor in children with neuroblastoma immediately after hematopoietic stem-cell transplantation: a Children's Cancer Group Study. J Clin Oncol 2000;18:4077-4085 (Pubitemid 32038400)
    • (2000) Journal of Clinical Oncology , vol.18 , Issue.24 , pp. 4077-4085
    • Fevzi Ozkaynak, M.1    Sondel, P.M.2    Krailo, M.D.3    Gan, J.4    Javorsky, B.5    Reisfeld, R.A.6    Matthay, K.K.7    Reaman, G.H.8    Seeger, R.C.9
  • 81
    • 33645679838 scopus 로고    scopus 로고
    • A Phase I clinical trial of the hu14.18-IL2 (EMD 273063) as a treatment for children with refractory or recurrent neuroblastoma and melanoma: A study of the Children's Oncology Group
    • Osenga KL, Hank JA, Albertini MR, et al. A Phase I clinical trial of the hu14.18-IL2 (EMD 273063) as a treatment for children with refractory or recurrent neuroblastoma and melanoma: a study of the Children's Oncology Group. Clin Cancer Res 2006;12:1750-1759
    • (2006) Clin Cancer Res , vol.12 , pp. 1750-1759
    • Osenga, K.L.1    Hank, J.A.2    Albertini, M.R.3
  • 82
    • 0024386838 scopus 로고
    • 131I-labeled anti-tenascin monoclonal antibody 81C6 in patients with gliomas and other intracranial malignancies
    • Zalutsky MR, Moseley RP, Coakham HB, et al. Pharmacokinetics and tumor localization of 131I-labeled anti-tenascin monoclonal antibody 81C6 in patients with gliomas and other intracranial malignancies. Cancer Res 1989;49:2807-2813 (Pubitemid 19143420)
    • (1989) Cancer Research , vol.49 , Issue.10 , pp. 2807-2813
    • Zalutsky, M.R.1    Moseley, R.P.2    Coakham, H.B.3    Coleman, R.E.4    Bigner, D.D.5
  • 86
    • 44849110617 scopus 로고    scopus 로고
    • A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost
    • Reardon DA, Zalutsky MR, Akabani G, et al. A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost. Neuro Oncol 2008;10:182-189
    • (2008) Neuro Oncol , vol.10 , pp. 182-189
    • Reardon, D.A.1    Zalutsky, M.R.2    Akabani, G.3
  • 88
    • 37649010802 scopus 로고    scopus 로고
    • Clinical experience with α-particle emitting 211At: Treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6
    • Zalutsky MR, Reardon DA, Akabani G, et al. Clinical experience with α-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6. J Nucl Med 2008;49:30-38
    • (2008) J Nucl Med , vol.49 , pp. 30-38
    • Zalutsky, M.R.1    Reardon, D.A.2    Akabani, G.3
  • 91
    • 0025945894 scopus 로고
    • Fc receptors and immunoglobulin binding factors
    • Fridman WH. Fc receptors and immunoglobulin binding factors. FASEB J 1991;5:2684-2690 (Pubitemid 21905820)
    • (1991) FASEB Journal , vol.5 , Issue.12 , pp. 2684-2690
    • Fridman, W.H.1
  • 93
    • 35648978158 scopus 로고    scopus 로고
    • Structure-function relationships of the variable domains of monoclonal antibodies approved for cancer treatment
    • A recent study attempting to identify structural attributes common among FDA approved antibodies
    • Magdelaine-Beuzelin C, Kaas Q, Wehbi V, et al. Structure-function relationships of the variable domains of monoclonal antibodies approved for cancer treatment. Crit Rev Oncol Hematol 2007;64:210-25 • A recent study attempting to identify structural attributes common among FDA approved antibodies.
    • (2007) Crit Rev Oncol Hematol , vol.64 , pp. 210-225
    • Magdelaine-Beuzelin, C.1    Kaas, Q.2    Wehbi, V.3
  • 94
    • 0026684815 scopus 로고
    • Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms
    • Yokota T, Milenic DE, Whitlow M, Schlom J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res 1992;52:3402-3408
    • (1992) Cancer Res , vol.52 , pp. 3402-3408
    • Yokota, T.1    Milenic, D.E.2    Whitlow, M.3    Schlom, J.4
  • 95
    • 33644659256 scopus 로고    scopus 로고
    • Principles and use of anti-CTLA4 antibody in human cancer immunotherapy
    • DOI 10.1016/j.coi.2006.01.011, PII S0952791506000148, Lymphocyte Development / Tumor Immunology
    • Peggs KS, Quezada SA, Korman AJ, Allison JP. Principles and use of anti-CTLA4 antibody in human cancer immunotherapy. Curr Opin Immunol 2006;18:206-213 (Pubitemid 43327304)
    • (2006) Current Opinion in Immunology , vol.18 , Issue.2 , pp. 206-213
    • Peggs, K.S.1    Quezada, S.A.2    Korman, A.J.3    Allison, J.P.4
  • 97
    • 34250363163 scopus 로고    scopus 로고
    • Tumour anti-vascular alpha therapy: A mechanism for the regression of solid tumours in metastatic cancer
    • DOI 10.1088/0031-9155/52/13/L01, PII S0031915507455567, L01
    • Allen BJ, Raja C, Rizvi S, et al. Tumour anti-vascular alpha therapy: a mechanism for the regression of solid tumours in metastatic cancer. Phys Med Biol 2007;52:L15-9 (Pubitemid 46908610)
    • (2007) Physics in Medicine and Biology , vol.52 , Issue.13
    • Allen, B.J.1    Raja, C.2    Rizvi, S.3    Song, E.Y.4    Graham, P.5


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