Comparative healing response after sirolimus- and paclitaxel-eluting stent implantation in a pig model of restenosis

Catheterization and Cardiovascular Interventions

Volumn 73, Issue 6, 2009, Pages 801-808

  Silva, Guilherme V ^a   Fernandes, Marlos R ^a   Madonna, Rosella ^a   Clubb, Fred ^a   Oliveira, Edie ^a   Jimenez Quevedo, Pilar ^a   Branco, Rodrigo ^a   Lopez, Javier ^a   Angeli, Franca S ^a   Sanz Ruiz, Ricardo ^a   Vaughn, William K ^a   Zheng, Yi ^a   Baimbridge, Fred ^a   Canales, John ^a   Cardoso, Cristiano O ^a   Assad, Joao A ^a   Falotico, Robert ^b   Perin, Emerson C ^a,c  

^a ST LUKE S EPISCOPAL HOSPITAL   (United States)

^b JOHNSON AND JOHNSON   (United States)

^c NONE   (United States)

Author keywords

Drug eluting; Endothelialization; Inflammation

Indexed keywords

PACLITAXEL; RAPAMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; CORONARY ARTERY CIRCUMFLEX BRANCH; DISEASE SEVERITY; DRUG ELUTING STENT; ELECTRON MICROSCOPY; HEALING; HISTOPATHOLOGY; IN-STENT RESTENOSIS; INFLAMMATION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; REVIEW; RIGHT CORONARY ARTERY; SWINE;

ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANIMALS; ANTIGENS, CD31; CARDIOVASCULAR AGENTS; CORONARY RESTENOSIS; CORONARY VESSELS; DISEASE MODELS, ANIMAL; DRUG-ELUTING STENTS; INFLAMMATION; PACLITAXEL; PLATELET-DERIVED GROWTH FACTOR; SIROLIMUS; SWINE; SWINE, MINIATURE; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 65549135886     PISSN: 15221946     EISSN: 1522726X     Source Type: Journal    
DOI: 10.1002/ccd.21879     Document Type: Review

References (16)

1. Morice MC, Serruys PW, Sousa JE, Fajadet J, Ban Hayashi E, Perin M, Colombo A, Schuler G, Barragan P, Guagliumi G, et al. A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med 2002;346:1773-1780.
2. Berger A, Stauffer JC, Seydoux C, Siegenthaler M, Benoit A, Goy JJ. Three-year follow-up of the first prospective randomized comparison between paclitaxel and sirolimus stents: The TAXi-LATE trial. Catheter Cardiovasc Interv 2007;70:163-166.
3. Boyden TF, Nallamothu BK, Moscucci M, Chan PS, Grossman PM, Tsai TT, Chetcuti SJ, Bates ER, Gurm HS, Meta-analysis of randomized trials of drug-eluting stents versus bare metal stents in patients with diabetes mellitus. Am J Cardiol 2007;99:1399-1402.
4. Galloe AM, Thuesen L, Kelbaek H, Thayssen P, Rasmussen K, Hansen PR, Bligaard N, Saunamaki K, Junket A, Aaroe J, et al. Comparison of paclitaxel- and sirolimus-eluting stents; in everyday clinical practice: The SORT OUT II randomized trial, JAMA 2008;299:409-416.
5. Kastrati A, Mehilli J, von Beckerath N, Dibra A, Hausleiter J, Pache J, Schuhlen H, Schmitt C, Dirschinger J, Schomig A. Sirolimus-eluting stent or paclitaxel-eluting stent vs balloon angioplasty for prevention of recurrences in patients with coronary in-stent restenosis: A randomized controlled trial. JAMA 2005;293:165-171.
6. Morice MC, Colombo A, Meier B, Serruys P, Tamburino C, Guagliumi G, Sousa E. Stoll HP. Sirolimus- vs paclitaxel-eluting stents in de novo coronary artery lesions: The REALITY trial: A randomized controlled trial. JAMA 2006;295:895-904.
7. Togni M, Eber S, Widmer J, Billinger M, Weraweser P, Cook S, Vogel R, Seiler C, Eberli FR, Maier W, et al. Impact of vessel size on outcome after implantation of sirolimus-eluting and paclitaxel-eluting stents: A subgroup analysis of the SIRTAX trial. J Am Coll Cardiol 2007;50:1123-1131.
8. Finn AV. Kolodgie FD, Harnek J, Guerrero U, Acampado E, Tefera K. Skorija K, Weber DK, Gold HK, Virmani R. Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents. Circulation 2005;112:270-278.
9. Kornowski R, Hong MK, Tio FO, Bramwell O, Wu H, Leon MB. In-Stent restenosis: Contributions of inflammatory responses and arterial injury to neointimal hyperplasia. J Am Coll Cardiol 1998;31:224-230.
10. Schwartz RS, Edelman ER, Carter A, Chronos N, Rogers C, Robinson KA, Waksman R. Weinberger J, Wilensky RL, Jensen DN, et al. Drug-eluting stents in preclinical studies: Recommended evaluation from a consensus group. Circulation 2002;106:1867-1873.
11. Schwartz RS, Huber KC, Murphy JG, Edwards WD, Canirud AR; Vlietstra RE, Holmes DR. Restenosis and the proportional neointimal response to coronary artery injury: Results in a porcine model. J Am Coll Cardiol 1992;19:267-274.
12. Suzuki T, Kopia G, Hayashi S, Bailey LR, Llanos G, Wilensky R, Klugherz BD, Papandreou G, Narayan P, Leon MB, et al. Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model. Circulation 2001;104:1188-1193.
13. Park DW. Park SW, Park KH, Lee BK, Kim YH. Lee CW, Hong MK, Kim JJ, Park SJ. Frequency of and risk factors for stent thrombosis after drug-eluting stent implantation during long-term follow-up. Am J Cardiol 2006;98:352-356.
14. Heldman AW, Cheng L, Jenkins GM, Heller PF, Kim DW, Ware M Jr, Nater C, Hruban RH, Rezai B, Abella BS, et al. Paclitaxel stent coating inhibits neointimal hyperplasia at 4 weeks in a porcine model of coronary restenosis. Circulation 2001;103:2289-2295.
15. Farb A, Heller PF, Shroff S, Cheng L. Kolodgie FD, Carter AJ, Scott DS, Froehlich J, Virmani R. Pathological analysis of local delivery of paclitaxel via a polymer-coated stent. Circulation 2001;104:473-479.
16. Drachman DE, Edelman ER, Seifert P, Groothuis AR, Bornstein DA, Kamath KR, Palasis M, Yang D, Nott SH, Rogers C. Neointimal thickening after stent delivery of paclitaxel: Change in composition and arrest of growth over six months. J Am Coll Cardiol 2000;36:2325-2332.