AguR is required for induction of the Streptococcus mutans agmatine deiminase system by low pH and agmatine

Applied and Environmental Microbiology

Volumn 75, Issue 9, 2009, Pages 2629-2637

  Liu, Yaling ^a   Zeng, Lin ^a   Burne, Robert A ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC CONDITIONS; AGMATINE; DELETION MUTANTS; DNA BINDING DOMAIN; EXTRACELLULAR; LINKER SCANNING MUTAGENESIS; MUTANT PROTEINS; NEGATIVE REGULATORS; S. MUTANS; STREPTOCOCCUS MUTANS; TRANS-MEMBRANE DOMAINS; TRANSCRIPTIONAL ACTIVATORS; WILD TYPES;

ACTIVATION ANALYSIS; BIOACTIVITY; CHEMICAL ACTIVATION; DNA; NUCLEIC ACIDS;

GENE EXPRESSION;

AGMATINE; AGMATINE DEIMINASE; ANTIPORTER; BACTERIAL DNA; BACTERIAL ENZYME; MUTANT PROTEIN; PUTRESCINE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; HYDROLASE; TRANSACTIVATOR PROTEIN;

BACTERIUM; DNA; ENZYME ACTIVITY; GENE EXPRESSION; MUTATION; PH; PROTEIN;

ACIDITY; AGUR GENE; ARTICLE; BACTERIAL GENE; BACTERIAL MEMBRANE; CONTROLLED STUDY; DELETION MUTANT; DNA BINDING; EXTRACELLULAR SPACE; GENE EXPRESSION REGULATION; GENE INSERTION; GENE ISOLATION; GENE MUTATION; MUTANT; MUTATIONAL ANALYSIS; NONHUMAN; OPERON; PH; PREDICTION; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; STREPTOCOCCUS MUTANS; TRANSCRIPTION INITIATION; WILD TYPE; BINDING SITE; BIOSYNTHESIS; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

STREPTOCOCCUS MUTANS;

AGMATINE; BACTERIAL PROTEINS; BINDING SITES; GENE EXPRESSION REGULATION, BACTERIAL; HYDROGEN-ION CONCENTRATION; HYDROLASES; MUTAGENESIS, INSERTIONAL; PROTEIN STRUCTURE, TERTIARY; STREPTOCOCCUS MUTANS; TRANS-ACTIVATORS;

EID: 65549128078     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.02145-08     Document Type: Article

References (31)

1. Ahn, S. J., J. A. Lemos, and R. A. Burne. 2005. Role of HtrA in growth and competence of Streptococcus mutans UA159. J. Bacteriol. 187:3028-3038.
2. Ahn, S. J., Z. T. Wen, and R. A. Burne. 2006. Multilevel control of compe- tence development and stress tolerance in Streptococcus mutans UA159. Infect. Immun. 74:1631-1642.
3. Bender, G. R., S. V. Sutton, and R. E. Marquis. 1986. Acid tolerance, proton permeabilities, and membrane ATPases of oral streptococci. Infect. Immun. 53:331-338.
4. Bryan, E. M., T. Bae, M. Kleerebezem, and G. M. Dunny. 2000. Improved vectors for nisin-controlled expression in gram-positive bacteria. Plasmid 44:183-190.
5. Burne, R. A., Z. T. Wen, Y. Y. Chen, and J. E. Penders. 1999. Regulation of expression of the fructan hydrolase gene of Streptococcus mutans GS-5 by induction and carbon catabolite repression. J. Bacteriol. 181:2863-2871.
6. Chen, Y. Y., M. J. Betzenhauser, and R. A. Burne. 2002. cis-Acting elements that regulate the low-pH-inducible urease operon of Streptococcus salivarius. Microbiology 148:3599-3608.
7. Chen, Y. Y., and R. A. Burne. 1996. Analysis of Streptococcus salivarius urease expression using continuous chemostat culture. FEMS Microbiol. Lett. 135:223-229.
8. Chen, Y. Y., C. A. Weaver, D. R. Mendelsohn, and R. A. Burne. 1998. Transcriptional regulation of the Streptococcus salivarius 57.I urease operon. J. Bacteriol. 180:5769-5775.
9. Eichenbaum, Z., M. J. Federle, D. Marra, W. M. de Vos, O. P. Kuipers, M. Kleerebezem, and J. R. Scott. 1998. Use of the lactococcal nisA promoter to regulate gene expression in gram-positive bacteria: comparison of induction level and promoter strength. Appl. Environ. Microbiol. 64:2763-2769.
10. Fuqua, C., M. R. Parsek, and E. P. Greenberg. 2001. Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing. Annu. Rev. Genet. 35:439-468.
11. Griswold, A. R., Y. Y. Chen, and R. A. Burne. 2004. Analysis of an agmatine deiminase gene cluster in Streptococcus mutans UA159. J. Bacteriol. 186: 1902-1904.
12. Griswold, A. R., M. Jameson-Lee, and R. A. Burne. 2006. Regulation and physiologic significance of the agmatine deiminase system of Streptococcus mutans UA159. J. Bacteriol. 188:834-841.
13. Griswold, A. R., M. N. Nascimento, and R. A. Burne. 2009. Distribution, regulation and role of the agmatine deiminase system in mutans streptococci. Oral Microbiol. Immunol. 24:79-82.
14. Kleerebezem, M., M. M. Beerthuyzen, E. E. Vaughan, W. M. de Vos, and O. P. Kuipers. 1997. Controlled gene expression systems for lactic acid bacteria: transferable nisin-inducible expression cassettes for Lactococ- cus, Leuconostoc, and Lactobacillus spp. Appl. Environ. Microbiol. 63: 4581-4584.
15. Kuipers, O. P., M. M. Beerthuyzen, P. G. de Ruyter, E. J. Luesink, and W. M. de Vos. 1995. Autoregulation of nisin biosynthesis in Lactococcus lactis by signal transduction. J. Biol. Chem. 270:27299-27304.
16. Kuper, C., and K. Jung. 2005. CadC-mediated activation of the cadBA promoter in Escherichia coli. J. Mol. Microbiol. Biotechnol. 10:26-39.
17. Kuramitsu, H. K. 1993. Virulence factors of mutans streptococci: role of molecular genetics. Crit. Rev. Oral Biol. Med. 4:159-176.
18. Lee, Y. H., J. H. Kim, I. S. Bang, and Y. K. Park. 2008. The membrane-bound transcriptional regulator CadC is activated by proteolytic cleavage in re- sponse to acid stress. J. Bacteriol. 190:5120-5126.
19. Lemos, J. A., J. Abranches, and R. A. Burne. 2005. Responses of cariogenic streptococci to environmental stresses. Curr. Issues Mol. Biol. 7:95-107.
20. Lemos, J. A., T. A. Brown, Jr., and R. A. Burne. 2004. Effects of RelA on key virulence properties of planktonic and biofilm populations of Streptococcus mutans. Infect. Immun. 72:1431-1440.
21. Lemos, J. A., and R. A. Burne. 2002. Regulation and physiological signifi- cance of ClpC and ClpP in Streptococcus mutans. J. Bacteriol. 184:6357-6366.
22. Levesque, C. M., R. W. Mair, J. A. Perry, P. C. Lau, Y. H. Li, and D. G. Cvitkovitch. 2007. Systemic inactivation and phenotypic characterization of two-component systems in expression of Streptococcus mutans virulence properties. Lett. Appl. Microbiol. 45:398-404.
23. Levin, P. 2002. Light microscopy techniques for bacterial cell biology. Meth- ods Microbiol. 31:115-132.
24. Li, Y. H., P. C. Lau, N. Tang, G. Svensater, R. P. Ellen, and D. G. Cvitko- vitch. 2002. Novel two-component regulatory system involved in biofilm formation and acid resistance in Streptococcus mutans. J. Bacteriol. 184: 6333-6342.
25. Neely, M. N., C. L. Dell, and E. R. Olson. 1994. Roles of LysP and CadC in mediating the lysine requirement for acid induction of the Escherichia coli cad operon. J. Bacteriol. 176:3278-3285.
26. Park, Y. K., B. Bearson, S. H. Bang, I. S. Bang, and J. W. Foster. 1996. Internal pH crisis, lysine decarboxylase and the acid tolerance response of Salmonella typhimurium. Mol. Microbiol. 20:605-611.
27. Senadheera, M. D., B. Guggenheim, G. A. Spatafora, Y. C. Huang, J. Choi, D. C. Hung, J. S. Treglown, S. D. Goodman, R. P. Ellen, and D. G. Cvitko- vitch. 2005. A VicRK signal transduction system in Streptococcus mutans affects gtfBCD, gbpB, and ftf expression, biofilm formation, and genetic competence development. J. Bacteriol. 187:4064-4076.
28. Slock, J., D. VanRiet, D. Kolibachuk, and E. P. Greenberg. 1990. Critical regions of the Vibrio fischeri LuxR protein defined by mutational analysis. J. Bacteriol. 172:3974-3979.
29. Wexler, D. L., M. C. Hudson, and R. A. Burne. 1993. Streptococcus mutans fructosyltransferase (ftf) and glucosyltransferase (gtfBC) operon fusion strains in continuous culture. Infect. Immun. 61:1259-1267.
30. Zeng, L., Z. T. Wen, and R. A. Burne. 2006. A novel signal transduction system and feedback loop regulate fructan hydrolase gene expression in Streptococcus mutans. Mol. Microbiol. 62:187-200.
31. Zubay, G., D. E. Morse, W. J. Schrenk, and J. H. Miller. 1972. Detection and isolation of the repressor protein for the tryptophan operon of Escherichia coli. Proc. Natl. Acad. Sci. USA 69:1100-1103.