Myeloperoxidase as inflammatory marker of periodontal disease: Experimental study in rats

Immunological Investigations

Volumn 38, Issue 2, 2009, Pages 117-122

  Gomes, Dbora A S ^a   Pires, Juliana R ^b   Zuza, Elizangela P ^b   Muscara, Marcelo N ^c   Herrera, Bruno S ^c   Spolidorio, Lus C ^a   Toledo, Benedicto E C ^b   Spolidorio, Denise M P ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b Educational Foundation of Barretos   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Enzymes; Inflammation; Periodontal diseases; Peroxidase

Indexed keywords

MYELOPEROXIDASE; BIOLOGICAL MARKER; PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE MARKER; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; INFECTION; INFLAMMATION; MOLAR TOOTH; NONHUMAN; PERIODONTAL DISEASE; PRIORITY JOURNAL; RAT; ANIMAL; DISEASE MODEL; ENZYMOLOGY; GINGIVA; IMMUNOLOGY; MALE; NEUTROPHIL; PERIODONTITIS; WISTAR RAT;

ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; GINGIVA; MALE; NEUTROPHILS; PERIODONTITIS; PEROXIDASE; RATS; RATS, WISTAR;

EID: 65549118885     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.1080/08820130802457503     Document Type: Article

References (18)

1. Bradley, P. P., Priebat, D. A., Christensen, R. D., Rothstein, G. (1982). Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78:206-209.
2. Buchmann, R., Hasilik, A., Van Dyke, T. E., Lange, D. E. (2002). Amplified crevicular leukocyte activity in agressive periodontal disease. J. Dent. Res. 81:716-721.
3. Dennison, D. K., Van Dyke, T. E. (1997). The acute inflammatory response and the role of phagocytic cells in periodontal health and disease. Periodontology 2000 14:54-78.
4. Holzhausen, M., Rossa, C. Jr., Marcantonio, E. Jr., Nassar, P. O., Spolidorio, D. M., Spolidorio, L. C. (2002). Effect of selective cyclooxygenase-2 inhibition on the development of ligature-induced periodontitis in rats. J. Periodontol. 73:1030-1036.
5. Holzhausen, M., Spolidorio, L. C., Vergnolle, N. (2005). Proteinase-activated receptor-2 (PAR2) agonist causes periodontitis in rats. J. Dent. Res. 84:154-159.
6. Ihalin, R., Loimaranta, V., Lenander-Lumikari, M., Tenovuo, J. (1998). The effects of different (pseudo) halide substrates on peroxidase-mediated killing of Actinobacillus actinomycetemcomitans. J. Periodontal Res. 33:421-427.
7. Johnson, I. H. (1975). Effects of local irritation and dextran sulphate administration on the periodontum of the rat. J. Periodontal Res. 10:332-345.
8. Klebanoff, S. J. (1968). Myeloperoxidase-halide-hydrogen peroxide antibacterial system. J. Bacteriol. 5:2131-2138.
9. Kowolik, M. J., Grant, M. (1983). Myeloperoxidase activity in human gingival crevicular neutrophils. Arch. Oral Biol. 28:293-295.
10. Liskmann, S., Zilmer, M., Vihalemm, T., Salum, O., Fischer, K. (2004). Correlation of peri-implant health and myeloperoxidase levels: a cross-sectional clinical study. Clin. Oral Implants Res. 15:546-552.
11. Nassar, C. A., Nassar, P. O., Abi Rached, R. S., Holzhausen, M., Marcantonio, E. Jr., Spolidorio, L.C. (2004). Effect of cyclosporin A on alveolar bone homeostasis in rat periodontitis model. J. Periodontal Res. 39:143-148. (Pubitemid 38692082)
12. Över, C., Yamalik, N., Yavuzyilmaz, E., Ersoy, F., Eratalay, K. (1993). Peripheral blood neutrophil, crevicular fluid and whole saliva myeloperoxidase activity in periodontal disease. J. Nihon. Univ. Sch. Dent. 35:235-240.
13. Saari, H. R., Suomalainen, O., Lindy, Y., Konttinen, T., Sorsa, T. (1990). Activation of latent human neutrophil collagenase by reactive oxygen species and serine proteases. Biochem. Biophys. Res. Commun. 171:979-987.
14. Smith, Q. T., Hinrichs, J. E., Melynk, R. S. (1986). Gingival crevicular fluid myeloperoxidase at periodontitis sites. J. Periodontal Res. 21:45-55.
15. Travis, J., Pike, R., Imamura, T., Potempa, J. (1994). The role of proteolytic enzymes in the development of pulmonary emphysema and periodontal disease. Am. J. Respir. Crit. Care Med. 150:S143-S146.
16. Wei, P. F., Ho, K. Y., Ho, Y. P., Wu, Y. M., Yang, Y. H., Tsai, C. C. (2004). The investigation of glutathione peroxidase, lactoferrin, myeloperoxidase and interleukin-1beta in gingival crevicular fluid: implications for oxidative stress in human periodontal diseases. J. Periodontal Res. 39:287-293.
17. Yamalik, N., Caglayan, F., Kilinc, K., Kilinc, A., Tumer, C. (2000). The importance of data presentation regarding gingival crevicular fluid myeloperoxidase and elastase-like activity in periodontal disease and health status. J. Periodontol. 71:460-467.
18. Zipfel, M., Carmine, T. C., Gerber, C., Niethammer, D., Bruchelt, G. (1997). Evidence for the activation of mieloperoxidase by f-meth-leuphe prior to its release from neutrophil granulocytes. Biochem. Biophys. Res.Commun. 232:209-212.