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Volumn 20, Issue 3, 2009, Pages 223-225

Safety and efficacy of intravitreal anti-VEGF injections for age-related macular degeneration

Author keywords

Humans; Injections; Safety; Treatment outcome

Indexed keywords

BEVACIZUMAB; PEGAPTANIB; RANIBIZUMAB; VASCULOTROPIN ANTIBODY; ANGIOGENESIS INHIBITOR; APTAMER; MONOCLONAL ANTIBODY; VASCULOTROPIN A;

EID: 65549113426     PISSN: 10408738     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICU.0b013e328329b656     Document Type: Review
Times cited : (42)

References (22)
  • 1
    • 34848832895 scopus 로고    scopus 로고
    • Overview of progress in the epidemiology of age-related macular degeneration
    • Klein R. Overview of progress in the epidemiology of age-related macular degeneration. Ophthalmic Epidemiol 2007; 14:184-187.
    • (2007) Ophthalmic Epidemiol , vol.14 , pp. 184-187
    • Klein, R.1
  • 2
    • 6344241300 scopus 로고    scopus 로고
    • The epidemiology of age-related macular degeneration
    • Seddon JM, Chen CA. The epidemiology of age-related macular degeneration. Int Ophthalmol Clin 2004; 44:17-39.
    • (2004) Int Ophthalmol Clin , vol.44 , pp. 17-39
    • Seddon, J.M.1    Chen, C.A.2
  • 3
    • 33749445317 scopus 로고    scopus 로고
    • Ranibizumab for neovascular age- related macular degeneration
    • Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular age- related macular degeneration. N Engl J Med 2006; 355:1419-1431.
    • (2006) N Engl J Med , vol.355 , pp. 1419-1431
    • Rosenfeld, P.J.1    Brown, D.M.2    Heier, J.S.3
  • 4
    • 0021752680 scopus 로고
    • Age-related macular degeneration and blindness due to neovascular maculopathy
    • Ferris FL 3rd, Fine SL, Hyman L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol 1984; 102:1640- 1642.
    • (1984) Arch Ophthalmol , vol.102 , pp. 1640-1642
    • Ferris 3rd, F.L.1    Fine, S.L.2    Hyman, L.3
  • 5
    • 33747075399 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide: A change in a paradigm
    • Jonas JB. Intravitreal triamcinolone acetonide: a change in a paradigm. Ophthalmic Res 2006; 38:218-245.
    • (2006) Ophthalmic Res , vol.38 , pp. 218-245
    • Jonas, J.B.1
  • 6
    • 11144239923 scopus 로고    scopus 로고
    • Pegaptanib for neovascular age-related macular degeneration
    • Gragoudas ES, Adamis AP, Cunningham ET Jr, et al. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med 2004; 351:2805- 2816.
    • (2004) N Engl J Med , vol.351 , pp. 2805-2816
    • Gragoudas, E.S.1    Adamis, A.P.2    Cunningham Jr, E.T.3
  • 7
    • 35448981510 scopus 로고    scopus 로고
    • Emerging therapies for neovascular age-related macular degeneration: State of the art
    • Donati G. Emerging therapies for neovascular age-related macular degeneration: state of the art. Ophthalmologica 2007; 221:366-377.
    • (2007) Ophthalmologica , vol.221 , pp. 366-377
    • Donati, G.1
  • 8
    • 33747891752 scopus 로고    scopus 로고
    • Chakravarthy U, Adamis AP, Cunningham ET Jr, et al. Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age- related macular degeneration. Ophthalmology 2006; 113:1508.e1- 1508.e25.
    • Chakravarthy U, Adamis AP, Cunningham ET Jr, et al. Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age- related macular degeneration. Ophthalmology 2006; 113:1508.e1- 1508.e25.
  • 9
    • 34548262708 scopus 로고    scopus 로고
    • Pegaptanib 1 -year systemic safety results from a safety-pharmacokinetic trial in patients with neovascular age- related macular degeneration
    • Apte RS, Modi M, Masonson H, et al. Pegaptanib 1 -year systemic safety results from a safety-pharmacokinetic trial in patients with neovascular age- related macular degeneration. Ophthalmology 2007; 114:1702-1712.
    • (2007) Ophthalmology , vol.114 , pp. 1702-1712
    • Apte, R.S.1    Modi, M.2    Masonson, H.3
  • 10
    • 37249081518 scopus 로고    scopus 로고
    • Intraocular pressure effects of pegaptanib (macugen) injections in patients with and without glaucoma
    • author reply 186
    • Lanzl IM, Maier M, Feucht N, etal. Intraocular pressure effects of pegaptanib (macugen) injections in patients with and without glaucoma. Am J Ophthalmol 2008; 145:185; author reply 186.
    • (2008) Am J Ophthalmol , vol.145 , pp. 185
    • Lanzl, I.M.1    Maier, M.2    Feucht, N.3
  • 11
    • 33746406774 scopus 로고    scopus 로고
    • new drug. In macular degeneration: Too many risks for too little benefit
    • Pegaptanib: new drug. In macular degeneration: too many risks for too little benefit. Prescrire Int 2006; 15:127-129.
    • (2006) Prescrire Int , vol.15 , pp. 127-129
    • Pegaptanib1
  • 12
    • 33846586501 scopus 로고    scopus 로고
    • Subgroup analysis of the MARINA study of ranibizumab in neovascular age-related macular degeneration
    • Boyer DS, Antoszyk AN, Awh CC, et al. Subgroup analysis of the MARINA study of ranibizumab in neovascular age-related macular degeneration. Ophthalmology 2007; 114:246-252.
    • (2007) Ophthalmology , vol.114 , pp. 246-252
    • Boyer, D.S.1    Antoszyk, A.N.2    Awh, C.C.3
  • 13
    • 38349172455 scopus 로고    scopus 로고
    • Regillo CD, Brown DM, Abraham P, et al. Randomized, double-masked, sham- controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER Study year 1. Am J Ophthalmol 2008; 145:239-248.This phase lllb, multicenter, randomized-controlled trial evaluated the efficacy and safety of ranibizumab administered monthly for 3 months and then quarterly in patients with subfoveal CNV secondary to AMD.
    • Regillo CD, Brown DM, Abraham P, et al. Randomized, double-masked, sham- controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER Study year 1. Am J Ophthalmol 2008; 145:239-248.This phase lllb, multicenter, randomized-controlled trial evaluated the efficacy and safety of ranibizumab administered monthly for 3 months and then quarterly in patients with subfoveal CNV secondary to AMD.
  • 14
    • 67649782286 scopus 로고    scopus 로고
    • Heier JS, Antoszyk AN, Pavan PR, et al. Ranibizumab for treatment of neovascular age-related macular degeneration: a phase l/ll multicenter, controlled, multidose study. Ophthalmology 2006; 113:633.e1-633.e4.
    • Heier JS, Antoszyk AN, Pavan PR, et al. Ranibizumab for treatment of neovascular age-related macular degeneration: a phase l/ll multicenter, controlled, multidose study. Ophthalmology 2006; 113:633.e1-633.e4.
  • 15
    • 33750314559 scopus 로고    scopus 로고
    • Ranibizumab combined with verteporfin photodynamic therapy in neovascular age-related macular degeneration: Year 1 results of the FOCUS Study
    • Heier JS, Boyer DS, Ciulla TA, et al. Ranibizumab combined with verteporfin photodynamic therapy in neovascular age-related macular degeneration: year 1 results of the FOCUS Study. Arch Ophthalmol 2006; 124:1532-1542.
    • (2006) Arch Ophthalmol , vol.124 , pp. 1532-1542
    • Heier, J.S.1    Boyer, D.S.2    Ciulla, T.A.3
  • 16
    • 20544478429 scopus 로고    scopus 로고
    • Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized phase II trial
    • Kabbinavar FF, Schulz J, McCleod M, et al. Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial. J Clin Oncol 2005; 23:3697-3705.
    • (2005) J Clin Oncol , vol.23 , pp. 3697-3705
    • Kabbinavar, F.F.1    Schulz, J.2    McCleod, M.3
  • 17
    • 27944458472 scopus 로고    scopus 로고
    • Bevacizumab combined with standard fluoropyr- imidine-based chemotherapy regimens to treat colorectal cancer
    • Hurwitz H, Kabbinavar F. Bevacizumab combined with standard fluoropyr- imidine-based chemotherapy regimens to treat colorectal cancer. Oncology 2005; 69 (Suppl 3):17-24.
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 17-24
    • Hurwitz, H.1    Kabbinavar, F.2
  • 18
    • 34247182509 scopus 로고    scopus 로고
    • Bevacizumab for neovascular ocular diseases
    • Lynch SS, Cheng CM. Bevacizumab for neovascular ocular diseases. Ann Pharmacother 2007; 41:614-625.
    • (2007) Ann Pharmacother , vol.41 , pp. 614-625
    • Lynch, S.S.1    Cheng, C.M.2
  • 19
    • 40549135324 scopus 로고    scopus 로고
    • Weigert G, Michels S, Sacu S, et al. Intravitreal bevacizumab (Avastin) therapy versus photodynamic therapy plus intravitreal triamcinolone for neovascular age-related macular degeneration: 6-month results of a prospective, randomised, controlled clinical study. Br J Ophthalmol 2008; 92:356-360. This randomized control trial compared the functional and anatomical outcomes of intravitreal bevacizumab and verteporfin (photodynamic therapy) combined with intravitreal triamcinolone in patients with neovascular AMD.
    • Weigert G, Michels S, Sacu S, et al. Intravitreal bevacizumab (Avastin) therapy versus photodynamic therapy plus intravitreal triamcinolone for neovascular age-related macular degeneration: 6-month results of a prospective, randomised, controlled clinical study. Br J Ophthalmol 2008; 92:356-360. This randomized control trial compared the functional and anatomical outcomes of intravitreal bevacizumab and verteporfin (photodynamic therapy) combined with intravitreal triamcinolone in patients with neovascular AMD.
  • 20
    • 36448993366 scopus 로고    scopus 로고
    • Twelve-month safety of intravitreal injections of bevacizumab (Avastin(R)): Results of the Pan-American Collaborative Retina Study Group (PACORES)
    • This large study reported the cumulative systemic and ocular adverse events following intravitreal bevacizumab during 12 months of follow-up
    • Wu L, Martinez-Castellanos MA, Quiroz-Mercado H, et al. Twelve-month safety of intravitreal injections of bevacizumab (Avastin(R)): results of the Pan-American Collaborative Retina Study Group (PACORES). Graefes Arch Clin Exp Ophthalmol 2008; 246:81 -87. This large study reported the cumulative systemic and ocular adverse events following intravitreal bevacizumab during 12 months of follow-up.
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , pp. 81-87
    • Wu, L.1    Martinez-Castellanos, M.A.2    Quiroz-Mercado, H.3
  • 21
    • 52949129894 scopus 로고    scopus 로고
    • Antivascular endothelial growth factor pharmacotherapy for age-related macular degeneration: A report by the American Academy of Ophthalmology
    • Ip MS, Scott IU, Brown GC, et al. Antivascular endothelial growth factor pharmacotherapy for age-related macular degeneration: a report by the American Academy of Ophthalmology. Ophthalmology 2008; 115:1837- 1846.
    • (2008) Ophthalmology , vol.115 , pp. 1837-1846
    • Ip, M.S.1    Scott, I.U.2    Brown, G.C.3
  • 22
    • 67649817401 scopus 로고    scopus 로고
    • This evidence-based review systemically reported the safety and efficacy of VEGF- A pharmacotherapies for the treatment of neovascular AMD
    • This evidence-based review systemically reported the safety and efficacy of VEGF- A pharmacotherapies for the treatment of neovascular AMD.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.