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Regillo CD, Brown DM, Abraham P, et al. Randomized, double-masked, sham- controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER Study year 1. Am J Ophthalmol 2008; 145:239-248.This phase lllb, multicenter, randomized-controlled trial evaluated the efficacy and safety of ranibizumab administered monthly for 3 months and then quarterly in patients with subfoveal CNV secondary to AMD.
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Regillo CD, Brown DM, Abraham P, et al. Randomized, double-masked, sham- controlled trial of ranibizumab for neovascular age-related macular degeneration: PIER Study year 1. Am J Ophthalmol 2008; 145:239-248.This phase lllb, multicenter, randomized-controlled trial evaluated the efficacy and safety of ranibizumab administered monthly for 3 months and then quarterly in patients with subfoveal CNV secondary to AMD.
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Weigert G, Michels S, Sacu S, et al. Intravitreal bevacizumab (Avastin) therapy versus photodynamic therapy plus intravitreal triamcinolone for neovascular age-related macular degeneration: 6-month results of a prospective, randomised, controlled clinical study. Br J Ophthalmol 2008; 92:356-360. This randomized control trial compared the functional and anatomical outcomes of intravitreal bevacizumab and verteporfin (photodynamic therapy) combined with intravitreal triamcinolone in patients with neovascular AMD.
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Twelve-month safety of intravitreal injections of bevacizumab (Avastin(R)): Results of the Pan-American Collaborative Retina Study Group (PACORES)
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This large study reported the cumulative systemic and ocular adverse events following intravitreal bevacizumab during 12 months of follow-up
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Antivascular endothelial growth factor pharmacotherapy for age-related macular degeneration: A report by the American Academy of Ophthalmology
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This evidence-based review systemically reported the safety and efficacy of VEGF- A pharmacotherapies for the treatment of neovascular AMD
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This evidence-based review systemically reported the safety and efficacy of VEGF- A pharmacotherapies for the treatment of neovascular AMD.
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