Role of matrix metalloproteinases in skin ageing

Connective Tissue Research

Volumn 50, Issue 2, 2009, Pages 132-138

  Sárdy, Miklós ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Chronological Ageing; Connective Tissue Degradation; Extracellular Matrix; Matrix Metalloproteinases; Photoageing; Skin Ageing

Indexed keywords

CYSTEINE; DOXYCYCLINE; GELATINASE A; HISTIDINE; INTERSTITIAL COLLAGENASE; ISOENZYME; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; RETINOIC ACID; STROMELYSIN 3; TISSUE INHIBITOR OF METALLOPROTEINASE; ZINC ION; ENZYME INHIBITOR; REACTIVE OXYGEN METABOLITE;

CUTANEOUS PARAMETERS; ENZYME INHIBITION; ENZYME STRUCTURE; EXTRACELLULAR MATRIX; HUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; REGULATORY MECHANISM; REVIEW; ULTRAVIOLET IRRADIATION; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; ULTRAVIOLET RADIATION;

ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; MATRIX METALLOPROTEINASES; REACTIVE OXYGEN SPECIES; SKIN AGING; ULTRAVIOLET RAYS;

EID: 65549112990     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.1080/03008200802585622     Document Type: Review

References (63)

1. Mandl, I., MacLennan, J.D., and Howes, E.L. (1953). Isolation and characterization of proteinase and collagenase from Cl. histolyticum. J. Clin. Invest., 32, 1323-1329.
2. Mandl, I. (1982). Bacterial collagenases and their clinical applications. Arzneimittelforschung, 32, 1381-1384.
3. Mandl, I., and Cohen, B.B. (1960). Bacterial elastase. I. Isolation, purification and properties. Arch. Biochem. Biophys., 91, 47-53.
4. Ra, H.J., and Parks, W.C. (2007). Control of matrix metalloproteinase catalytic activity. Matrix Biol., 26, 587-596.
5. Nagase, H., Visse, R., and Murphy, G. (2006). Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc. Res., 69, 562-573.
6. http://merops.sanger.ac.uk/. Accessed: October 25, 2008.
7. Van Wart, H.E., and Birkedal-Hansen, H. (1990). The cysteine switch: A principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc Natl Acad Sci USA, 87, 5578-5582.
8. Pei, D., and Weiss, S.J. (1995). Furin-dependent intracellular activation of the human stromelysin-3 zymogen. Nature, 375, 244-247.
9. Sato, H., Kinoshita, T., Takino, T., Nakayama, K., and Seiki, M. (1996). Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP-2). FEBS Lett., 393, 101-104.
10. Kang, T., Nagase, H., and Pei, D. (2002). Activation of membrane-type matrix metalloproteinase 3 zymogen by the proprotein convertase furin in the trans-Golgi network. Cancer Res., 62, 675-681.
11. Bode,W., Gomis-Ruth, F.X., and Stöckler,W. (1993). Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments(HEXXHXXGXXHandMet-turn) and topologies and should be grouped into a common family, the 'metzincins.' FEBS Lett. 331, 134-140.
12. Limb, G.A., Matter, K., Murphy, G., Cambrey, A.D., Bishop, P.N., Morris, G.E., and Khaw, P.T. (2005). Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C degradation during apoptosis. Am. J. Pathol., 166, 1555-1563.
13. Kwan, J.A., Schulze, C.J., Wang, W., Leon, H., Sariahmetoglu, M., Sung, M., Sawicka, J., Sims, D.E., Sawicki, G., and Schulz, R. (2004). Matrix metalloproteinase-2 (MMP-2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP-ribose) polymerase (PARP) in vitro. FASEB J., 18, 690-692.
14. Luo, D., Mari, B., Stoll, I., and Anglard, P. (2002). Alternative splicing and promoter usage generates an intracellular stromelysin 3 isoform directly translated as an active matrix metalloproteinase. J. Biol. Chem., 277, 25527-25536.
15. Wang, W., Schulze, C.J., Suarez-Pinzon, W.L., Dyck, J.R., Sawicki, G., and Schulz, R. (2002). Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury. Circulation, 106, 1543-1549.
16. Sawicki, G., Leon, H., Sawicka, J., Sariahmetoglu, M., Schulze, C.J., Scott, P.G., Szczesna-Cordary, D., and Schulz, R. (2005). Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: A new intracellular target for matrix metalloproteinase-2. Circulation, 112, 544-552.
17. Bruckner-Tuderman, L. (2007). Biology of the extracellular matrix. In Dermatology 2nd ed., Bolognia, J.L., Jorizzo, J.L., and Rapini, R.P. (eds.), pp. 1447-1454. (Elsevier Ltd., London).
18. http://www.clip.ubc.ca/mmp timp folder/mmp substrates.shtm. Accessed: October 25, 2008.
19. Newby, A.C. (2005). Dual role of matrix metalloproteinases (matrixins) in intimal thickening and atherosclerotic plaque rupture. Physiol. Rev., 85, 1-31.
20. Kobayashi, Y. (1997). Langerhans' cells produce type IV collagenase (MMP-9) following epicutaneous stimulation with haptens. Immunology 90, 496-501.
21. Yan, C., and Boyd, D.D. (2007). Regulation of matrix metalloproteinase gene expression. J. Cell Physiol., 211, 19-26.
22. Okamoto, T., Akaike, T., Sawa, T., Miyamoto, Y., van der Vliet, A., and Maeda, H. (2001).Activation ofmatrix metalloproteinases by peroxynitriteinduced protein S-glutathiolation via disulfide S-oxide formation. J. Biol. Chem., 276, 29596-29602.
23. Wang, W., Sawicki, G., and Schulz, R. (2002). Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2. Cardiovas. Res., 53, 165-174.
24. Nagase, H., Enghild, J.J., Suzuki, K., and Salvesen, G. (1990). Stepwise activation mechanisms of the precursor of matrix metalloproteinase 3 (stromelysin) by proteinases and (4-aminophenyl) mercuric acetate. Biochemistry, 29, 5783-5789.
25. Pohar, N., Godenschwege, T. A., and Buchner, E. (1999). Invertebrate tissue inhibitor ofmetalloproteinase: Structure and nested gene organization within the synapsin locus is conserved from Drosophila to human. Genomics, 57, 293-296.
26. Brew, K., Dinakarpandian, D., and Nagase, H. (2000). Tissue inhibitors of metalloproteinases: Evolution, structure and function. Biochim. Biophys. Acta., 1477, 267-283.
27. Isnard, N., Péterszegi, G., Robert, A.M., and Robert, L. (2002). Regulation of elastase-type endopeptidase activity, MMP-2 and MMP-9 expression and activation in human dermal fibroblasts by fucose and a fucose-rich polysaccharide. Biomed. Pharmacother., 56, 258-264.
28. Isnard, N., Bourles-Dagonet, F., Robert, L., and Renard, G. (2005). Studies on corneal wound healing. Effect of fucose on iodine vapor-burnt rabbit corneas. Ophthalmologica., 219, 324-333.
29. Sariahmetoglu, M., Crawford, B.D., Leon, H., Sawicka, J., Li, L., Ballermann, B.J., Holmes, C., Berthiaume, L.G., Holt, A., Sawicki, G., and Schulz, R. (2007). Regulation of matrix metalloproteinase-2 (MMP-2) activity by phosphorylation. FASEB J., 21, 2486-2495.
30. Chow, A.K., Cena, J., and Schulz, R. (2007). Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature. Br. J. Pharmacol., 152, 189-205.
31. Gürkan, A., Çinarcik, S., and Hüseyinov, A. (2005). Adjunctive subantimicrobial dose doxycycline: Effect on clinical parameters and gingival crevicular fluid transforming growth factor-β1 levels in severe, generalized chronic periodontitis. J. Clin. Periodontol., 32, 244-253.
32. Paixão-Cavalcante, D., van den Berg, C.W., Gonçalves-de-Andrade, R.M., Fernandes-Pedrosa Mde, F., Okamoto, C.K., and Tambourgi, D.V. (2007). Tetracycline protects against dermonecrosis induced by Loxosceles spider venom. J. Invest. Dermatol., 127, 1410-1418.
33. Turner, N.A., Aley, P.K., Hall, K.T., Warburton, P., Galloway, S., Midgley, L., O'Regan, D.J., Wood, I.C., Ball, S.G., and Porter, K.E. (2007). Simvastatin inhibits TNFa-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and independent mechanisms. J. Mol. Cell. Cardiol., 43, 168-176.
34. Braverman, I.M., and Fonferko, E. (1982). Studies in cutaneous aging: I. The elastic fiber network. J. Invest. Dermatol., 78, 434-443.
35. Lavker, R.M., Zheng, P.S., and Dong, G. (1987). Aged skin: A study by light, transmission electron, and scanning electron microscopy. J. Invest. Dermatol., 88 (3 suppl), 44s-51s.
36. Lavker, R.M. (1979). Structural alterations in exposed and unexposed aged skin. J. Invest. Dermatol., 73, 59-66.
37. Fisher, G.J., Datta, S.C., Talwar, H.S., Wang, Z.Q., Varani, J., Kang, S., and Voorhees, J.J. (1996). Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature, 379, 335-339.
38. Fisher, G.J., Kang, S., Varani, J., Bata-Csörgõ, Z., Wan, Y., Datta, S., and Voorhees, J.J. (2002). Mechanisms of photoaging and chronological skin aging. Arch. Dermatol., 138, 1462-1470.
39. Varani, J., Warner, R.L., Gharaee-Kermani, M., Phan, S.H., Kang, S., Chung, J.H., Wang, Z.Q., Datta, S.C., Fisher, G.J., and Voorhees, J.J. (2000). Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J. Invest. Dermatol., 114, 480-486.
40. Yaar, M., and Gilchrest, B.A. (2007). Photoageing: Mechanism, prevention and therapy. Br. J. Dermatol., 157, 874-887.
41. Lee, H.C., and Wei, Y.H. (2007). Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging. Exp. Biol. Med. (Maywood), 232, 592-606.
42. Moulin, G., Thomas, L.,Vigneau,M., and Fiere, A. (1994).Un cas unilateral d'elastose avec kystes et comedons de Favre et Racouchot. Ann. Dermatol. Venereol., 121, 721-723.
43. Xu,Y., Shao,Y.,Voorhees, J.J., and Fisher, G.J. (2006).Oxidative inhibition of receptor-type protein-tyrosine phosphatase ? by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes. J. Biol. Chem., 281, 27389-27397.
44. Denu, J.M., and Tanner, K.G. (1998). Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation. Biochemistry, 37, 5633-5642.
45. Nelson, K.K., and Melendez, J.A. (2004). Serial review: The powerhouse takes control of the cell: The role of mitochondria in signal transduction. Mitochondrial redox control of matrix metalloproteinases. Free Rad. Biol. Med., 37, 768-784.
46. Pimienta, G., and Pascual, J. (2007). Canonical and alternative MAPK signaling. Cell Cycle, 6, 2628-2632.
47. Quan, T., He, T., Kang, S., Voorhees, J.J., and Fisher, G.J. (2004). Solar ultraviolet irradiation reduces collagen in photoaged human skin by blocking transforming growth factor-β type II receptor/Smad signaling. Am. J. Pathol., 165, 741-751.
48. Fisher, G.J., Choi, H.C., Bata-Csörgõ, Z., Shao, Y., Datta, S., Wang, Z.Q., Kang, S., and Voorhees, J.J. (2001). Ultraviolet irradiation increases matrix metalloproteinase-8 protein in human skin in vivo. J. Invest. Dermatol., 117, 219-226.
49. Soter, N.A. (1990) Acute effects of ultraviolet radiation on the skin. Semin. Dermatol., 9, 11-15.
50. Gilchrest, B.A., Soter, N.A., Hawk, J.L., Barr, R.M., Black, A.K., Hensby, C.N., Mallet, A.I., Greaves, M.W., and Parrish, J.A. (1983) Histologic changes associated with ultraviolet A-induced erythema in normal human skin. J. Am. Acad. Dermatol., 9, 213-219.
51. Mallya, S.K., Mookhtiar, K.A., Gao, Y., Brew, K., Diószegi, M., Birkedal-Hansen, H., and van Wart, H.E. (1990). Characterization of 58-kilodalton human neutrophil collagenase: Comparison with human fibroblast collagenase. Biochemistry, 29, 10628-10634.
52. Strickland, I., Rhodes, L.E., Flanagan, B.F., and Friedman, P.S. (1997) TNF-a and IL-8 are upregulated in the epidermis of normal human skin after UVB exposure: Correlation with neutrophil accumulation and E-selectin expression. J. Invest. Dermatol., 108, 763-768.
53. Rijken, F., Kiekens, R.C., and Bruijnzeel, P.L. (2005). Skin-infiltrating neutrophils following exposure to solar-simulated radiation could play an important role in photoageing of human skin. Br. J. Dermatol., 152, 321-328.
54. Ashcroft, G.S., Herrick, S.E., Tarnuzzer, R.W., Horan, M.A., Schultz, G.S., and Ferguson, M.W. (1997). Human ageing impairs injury-induced in vivo expression of tissue inhibitor of matrix metalloproteinases (TIMP)-1 and -2 proteins and mRNA. J. Pathol., 183, 169-176.
55. Südel, K.M., Venzke, K., Knussmann-Hartig, E., Moll, I., Stäb, F., Wenck, H., Wittern, K.P., Gercken, G., and Gallinat, S. (2003). Tight control of matrix metalloproteinase-1 activity in human skin. Photochem. Photobiol., 78, 355-360.
56. Weiss, J.S., Ellis, C.N., Headington, J.T., Tincoff, T., Hamilton, T.A., and Voorhees, J.J. (1988). Topical tretinoin improves photoaged skin: A doubleblind, vehicle-controlled study. J. Am. Acad. Dermatol., 159, 527-532.
57. Griffiths, C.E.M., Russman, A.N., Majmudar, G., Singer, R.S., Hamilton, T.A., and Voorhees, J.J. (1993). Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid). N. Engl. J. Med., 329, 530-535.
58. Kligman, A.M., Dogadkina, D., and Lavker, R.M. (1993). Effects of topical tretinoin on non-sun-exposed protected skin of the elderly. J. Am. Acad. Dermatol., 29, 25-33.
59. Watson, R.E.B., Arjuna Ratnayaka, J., Brooke, R.C.C., Yee-Sit-Yu, S., Ancian, P., and Griffiths, C.E.M. (2004). Retinoic acid receptor alpha expression and cutaneous ageing. Mech. Ageing Dev., 125, 465-473.
60. Lahmann, C., Bergemann, J., Harrison, G., and Young, A.R. (2001). Matrix metalloproteinase-1 and skin ageing in smokers. Lancet, 357, 935-936.
61. Yin, L.,Morita, A., and Tsuji, T. (2000). Alterations of extracellular matrix induced by tobacco smoke extract. Arch. Dermatol. Res., 292, 188-194.
62. Hensley, K., and Floyd, R.A. (2002). Reactive oxygen species and protein oxidation in aging: A look back, a look ahead. Arch. Biochem. Biophys., 397, 377-383.
63. Arnold, R.S., Shi, J., Murad, E., Whalen, A.M., Sun, C.Q., Polavarapu, R., Parthasarathy, S., Petros, J.A., and Lambeth, J.D. (2001). Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1. Proc. Natl. Acad. Sci. USA, 98, 5550-5555.