Comparison of lectin binding of drusen, RPE, Bruch's membrane, and photoreceptors

Molecular Vision

Volumn 15, Issue , 2009, Pages 906-911

  D'Souza, Yvonne B ^a   Jones, Carolyn J P ^b   Bonshek, Richard E ^a,c  

^a MANCHESTER ROYAL EYE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AVIDIN; FUCOSE; GALACTOSE; GLYCAN; LECTIN; MANNOSE; N ACETYLGALACTOSAMINE; N ACETYLGLUCOSAMINE; PEROXIDASE; SIALIDASE;

ARTICLE; BRUCH MEMBRANE; CONTROLLED STUDY; DRUSEN; GLYCOSYLATION; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; LECTIN BINDING; PATHOGENESIS; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; TISSUE SECTION;

BIOTIN; BRUCH MEMBRANE; HISTOCYTOCHEMISTRY; HUMANS; LECTINS; MACULAR DEGENERATION; NEURAMINIDASE; PHOTORECEPTOR CELLS, VERTEBRATE; PROTEIN BINDING; RETINAL DRUSEN; RETINAL PIGMENT EPITHELIUM;

EID: 65549112549     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Abdelsalam A, Priore LD, Zarbin MA. Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression. Surv Ophthalmol 1999; 44:1-29.
2. Zarbin MA. Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol 2004; 122:598-614.
3. Sarks JP, Sarks SH, Killingsworth MC. Evolution of soft drusen in age-related macular degeneration. Eye 1994; 8:269-83.
4. Farkas TG, Sylvester V. The ultrastructure of drusen. Am J Ophthalmol 1971; 71:1196-205
5. Bishop PN, Boulton M, McLeod D, Stoddart RW. Glycan localisation within the human interphotoreceptor matrix and photoreceptor inner and outer segments. Glycobiology 1993; 3:403-12.
6. Fong SL, Liou GI, Landers RA, Gonsalez-Fernandez F, Glazebrook PA. Lam DM et el. Characterisation, localisation and biosynthesis of an interstitial retinal-binding glycoprotein in the human eye. J Neurochem 1984; 42:1667-75.
7. Uehara F, Ohba N, Ozawa M. Isolation and characterization of mucinlike glycoprotein associated with photoreceptor cells. Invest Ophthalmol Vis Sci 2000; 41:2759-65.
8. Jones CJP, Carter AM, Enders AC. Glycosylation at the fetomaternal interface in haemomonochorial placentae from five widely separated species of mammal: is there evidence for convergent evolution? Cells Tissues Organs 2007; 185:269-84.
9. Jones CJP, Morrison CA, Stoddart RW. Histochemical analysis of rat testicular glycoconjugates 2) β-galactosyl residues in O-and N-linked glycans in seminiferous tubules. Histochem J 1992; 24:327-36.
10. D'souza Y. Jones CJ, Bonshek RE. Glycoproteins of drusen and drusen-like lesions. J Mol Histol 2008; 39:77-86.
11. Fischer E, Brossner R. Sialic acid-binding lectins: Submolecular specificity and interaction with sialoglycoproteins and tumour cells. Glycoconj J 1995; 12:707-13.
12. Piller V, Piller F, Cartron JP. Comparison of the carbohydrate-binding specificities of seven N-acetyl-D-galactosamine recognising lectins. Eur J Biochem 1990; 191:461-6.
13. Jones CJP, Mosley S, Jeffrey IJM, Stoddart RW. Elimination of the non-specific binding of avidin to tissue sections. Histochem J 1987; 19:264-8.
14. Kivela T. Characterisation of galactose-containing glycoconjugates in the human retina: a lectin histochemical study. Curr Eye Res 1990; 9:1195-205.
15. Mullins RF, Johnson L, Anderson D, Hageman GS. Characterization of drusen-associated glycoconjugates. Ophthalmology 1997; 104:288-94.
16. Nakagawa M, Miyamoto T, Kusakabe R, Takasaki S, Takao T, Shichide Y, Tsuda M. O-glycosylation of G-protein-coupled receptor, octopus rhodopsin. Direct analysis by FAB mass spectrometry. FEBS Lett 2001; 496:19-24.
17. Fujita S, Endo T, Ju J, Kean EL, Kobata A. Structural studies of the N-linked sugar chains of human rhodopsin. Glycobiology 1994; 4:633-40.
18. Molday RS. Photoreceptor membrane proteins, phototransduction, and retinal degenerative diseases. The Friedenwald Lecture. Invest Ophthalmol Vis Sci 1998; 39:2491-513.
19. Lentrichia BB, Bruner WE, Kean EL. Glycosidases of the retinal pigment epithelium. Invest Ophthalmol Vis Sci 1978; 17:884-95.
20. Cingle KA, Kalski RS, Bruner WE, O'Brien CM, Erhard P, Wyszynski RE. Age-related changes of glycosidases in human retinal pigment epithelium. Curr Eye Res 1996; 15:433-8.