Mass antibiotic treatment atone does not eliminate ocular chlamydial infection

PLoS Neglected Tropical Diseases

Volumn 3, Issue 3, 2009, Pages

  Emerson, Paul M ^a   Ngondi, Jeremiah ^a,b  

^a CARTER CENTER   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; AZITHROMYCIN; TETRACYCLINE; ANTIINFECTIVE AGENT;

ANTIBIOTIC THERAPY; BACTERIAL EYE INFECTION; BACTERIAL TRANSMISSION; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; ENVIRONMENTAL FACTOR; EYE SURGERY; HEALTH CARE DISTRIBUTION; HEALTH PROGRAM; HEALTH PROMOTION; HUMAN; INFECTION CONTROL; LABORATORY TEST; NOTE; OUTCOME ASSESSMENT; PATIENT MONITORING; PERSONAL HYGIENE; SINGLE DRUG DOSE; TRACHOMA; WORLD HEALTH ORGANIZATION; BLINDNESS; MICROBIOLOGY; TREATMENT OUTCOME;

ANTI-BACTERIAL AGENTS; AZITHROMYCIN; BLINDNESS; CHLAMYDIA TRACHOMATIS; HUMANS; TETRACYCLINE; TRACHOMA; TREATMENT OUTCOME;

EID: 65549109309     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pntd.0000394     Document Type: Note

References (22)

1. World Health Organization (1997) Future Approaches to Trachoma Control: report of a global scientific meeting; Geneva 17-20 June 1996. Geneva: WHO document WHO/PBL/96.56.
2. Solomon AW, Zondervan M, Kuper H, Buchan J, Mabey D, et al. (2006) Trachoma control: a guide for programme managers. Geneva: World Health Organization.
3. Solomon AW, Holland MJ, Alexander ND, Massae PA, Aguirre A, et al. (2004) Mass treatment with single-dose azithromycin for trachoma. N Engl J Med 351: 1962-1971.
4. Solomon AW, Harding-Esch E, Alexander ND, Aguirre A, Holland MJ, et al. (2008) Two doses of azithromycin to eliminate trachoma in a Tanzanian community. N Engl J Med 358: 1870-1871.
5. Burton MJ, Holland MJ, Makalo P, Aryee EA, Alexander ND, et al. (2005) Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study. Lancet 365: 1321-1328.
6. West SK, Munoz B, Mkocha H, Holland MJ, Aguirre A, et al. (2005) Infection with Chlamydia trachomatis after mass treatment of a trachoma hyperendemic community in Tanzania: a longitudinal study. Lancet 366: 1296-1300.
7. West SK, Munoz B, Mkocha H, Gaydos C, Quinn T (2007) Trachoma and ocular Chlamydia trachomatis were not eliminated three years after two rounds of mass treatment in a trachoma hyperendemic village. Invest Ophthalmol Vis Sci 48: 1492-1497.
8. Lakew T, House J, Hong KC, Yi E, Alemayehu W, et al. (2009) Reduction and return of infectious trachoma in severely affected communities of Ethiopia. PLoS Negl Trop Dis 3: e376. doi:10.1371/journal.pntd.0000376.
9. Melese M, Chidambaram JD, Alemayehu W, Lee DC, Yi EH, et al. (2004) Feasibility of eliminating ocular Chlamydia trachomatis with repeat mass antibiotic treatments. JAMA 292: 721-725.
10. Ray KJ, Porco TC, Hong KC, Lee DC, Alemayehu W, et al. (2007) A rationale for continuing mass antibiotic distributions for trachoma. BMC Infect Dis 7: 91.
11. Melese M, Alemayehu W, Lakew T, Yi E, House J, et al. (2008) Comparison of annual and biannual mass antibiotic administration for elimination of infectious trachoma. JAMA 299: 778-784.
12. Gill DA, Lakew T, Alemayehu W, Melese M, Zhou Z, et al. (2008) Complete elimination is a difficult goal for trachoma programs in severely affected communities. Clin Infect Dis 46: 564-566.
13. Chidambaram JD, Alemayehu W, Melese M, Lakew T, Yi E, et al. (2006) Effect of a single mass antibiotic distribution on the prevalence of infectious trachoma. JAMA 295: 1142-1146.
14. Chidambaram JD, Melese M, Alemayehu W, Yi E, Prabriputaloong T, et al. (2004) Mass antibiotic treatment and community protection in trachoma control programs. Clin Infect Dis 39: e95-e97.
15. Chidambaram JD, Lee DC, Porco TC, Lietman TM (2005) Mass antibiotics for trachoma and the Allee effect. Lancet Infect Dis 5: 194-196.
16. Wright HR, Taylor HR (2005) Clinical examination and laboratory tests for estimation of trachoma prevalence in a remote setting: what are they really telling us? Lancet Infect Dis 5: 313-320.
17. Ngondi J, Onsarigo A, Matthews F, Reacher M, Brayne C, et al. (2006) Effect of 3 years of SAFE (surgery, antibiotics, facial cleanliness, and environmental change) strategy for trachoma control in southern Sudan: a cross-sectional study. Lancet 368: 589-595.
18. Ngondi J, Gebre T, Shargie EB, Adamu L, Ejigsemahu Y, et al. (2009) Evaluation of three years of the SAFE strategy (Surgery, Antibiotics, Facial cleanliness and Environmental improvement) for trachoma control in five districts of Ethiopia hyper-endemic for trachoma. Trans R Soc Trop Med Hyg. In press.
19. Solomon AW, Peeling RW, Foster A, Mabey DC (2004) Diagnosis and assessment of trachoma. Clin Microbiol Rev 17: 982-1011, table.
20. Solomon AW, Holland MJ, Burton MJ, West SK, Alexander ND, et al. (2003) Strategies for control of trachoma: observational study with quantitative PCR. Lancet 362: 198-204.
21. Burton MJ, Holland MJ, Faal N, Aryee EA, Alexander ND, et al. (2003) Which members of a community need antibiotics to control trachoma? Conjunctival Chlamydia trachomatis infection load in Gambian villages. Invest Ophthalmol Vis Sci 44: 4215-4222.
22. West SK, Munoz B, Mkocha H, Hsieh YH, Lynch MC (2001) Progression of active trachoma to scarring in a cohort of Tanzanian children. Ophthalmic Epidemiol 8: 137-144.