CD59 Silencing via retrovirus-mediated RNA interference enhanced complement-mediated cell damage in ovary cancer

Cellular and Molecular Immunology

Volumn 6, Issue 1, 2009, Pages 61-66

  Shi, Xuexiang ^a,b   Zhang, Bei ^a   Zang, Jinlin ^c   Wang, Guoying ^a   Gao, Meihua ^a  

^a QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^b Qingdao Center for Disease Control and Prevention   (China)

^c QINGDAO MUNICIPAL HOSPITAL   (China)

Author keywords

CD59; Complement; Gene therapy; Ovary cancer; RNA interference

Indexed keywords

CASPASE 3; CD59 ANTIGEN; COMPLEMENT; SMALL INTERFERING RNA; SHORT HAIRPIN RNA; VIRUS RNA; REGULATOR PROTEIN;

ANIMAL; APOPTOSIS; ARTICLE; DRUG EFFECT; DRUG SCREENING; FEMALE; GENE SILENCING; GENE THERAPY; GENE VECTOR; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE; NUDE MOUSE; OVARY TUMOR; PHYSIOLOGY; RNA INTERFERENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; CANCER INHIBITION; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; DNA SEQUENCE; GENE CONSTRUCT; HUMAN CELL; HUMAN TISSUE; NONHUMAN; OVARY CANCER; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; RETROVIRUS; RNA VIRUS; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; VIRUS RECOMBINANT; WESTERN BLOTTING; ANIMAL CELL; ANIMAL TISSUE; COMPLEMENT FIXATION; CYTOLYSIS; GENE OVEREXPRESSION; GROWTH INHIBITION; PROTEIN EXPRESSION;

ANIMALS; ANTIGENS, CD59; APOPTOSIS; CASPASE 3; COMPLEMENT SYSTEM PROTEINS; FEMALE; GENE SILENCING; GENE THERAPY; GENETIC VECTORS; HUMANS; MICE; MICE, NUDE; OVARIAN NEOPLASMS; RNA INTERFERENCE; RNA, SMALL INTERFERING; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS MUSCULUS;

EID: 65549109036     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2009.8     Document Type: Article

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