Ultrahigh speed spectral / Fourier domain ophthalmic OCT imaging

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7163, Issue , 2009, Pages

  Potsaid, Benjamin ^a,c   Gorczynska, Iwona ^a,b   Srinivasan, Vivek J ^a   Chen, Yueli ^a,b   Liu, Jonathan ^a   Jiang, James ^c   Cable, Alex ^c   Duker, Jay S ^b   Fujimoto, James G ^a,b  

^a Department of Electrical Engineering and Computer Science   (United States)

^b TUFTS UNIVERSITY   (United States)

^c THORLABS INC   (United States)

Author keywords

CMOS camera; Fovea and optic nerve head; Medical and biological imaging; Ophthalmology; Spectral Fourier domain OCT; Ultrahigh speed optical coherence tomography

Indexed keywords

CMOS CAMERA; FOVEA AND OPTIC NERVE HEAD; MEDICAL AND BIOLOGICAL IMAGING; SPECTRAL / FOURIER DOMAIN OCT; ULTRAHIGH SPEED OPTICAL COHERENCE TOMOGRAPHY;

BLOOD; CAMERAS; COHERENT LIGHT; DISKS (STRUCTURAL COMPONENTS); EYE PROTECTION; FOURIER TRANSFORMS; IMAGE ACQUISITION; OPHTHALMOLOGY; OPTICAL TESTING; OPTICAL TOMOGRAPHY; SPEED; THREE DIMENSIONAL; TOMOGRAPHY; VOLUMETRIC ANALYSIS;

MEDICAL IMAGING;

EID: 65549101671     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.809058     Document Type: Conference Paper

References (33)

1. Huang, D., Swanson, E. A., Lin, C. P., Schuman, J. S., Stinson, W. G., Chang, W., Hee, M. R., Flotte, T., Gregory, K., Puliafito, C. A., and Fujimoto, J. G., "Optical coherence tomography," Science 254(5035), 1178-1181 (1991).
2. Schuman, J. S., Puliafito, C. A., and Fujimoto, J. G., [Optical Coherence Tomography of Ocular Diseases], Slack, Inc., New Jersey, USA (2004).
3. Hitzenberger, C. K., "Optical measurement of the axial eye length by laser doppler interferometry.," Invest. Ophthalmol. Vis. Sci. 32, 616-624 (1991).
4. Swanson, E. A., Izatt, J. A., Hee, M. R., Huang, D., Lin, C. P., Schuman, J. S., Puliafito, C. A., and Fujimoto, J. G., "In-vivo retinal imaging by optical coherence tomography," Opt. Lett. 18(21), 1864-1866 (1993).
5. Fercher, A. F., Hitzenberger, C. K., Drexler, W., Kamp, G., and Sattmann, H., "In vivo optical coherence tomography," Am. J. Ophthalmol. 1(116), 113-114 (1993).
6. Drexler, W., Morgner, U., Ghanta, R. K., Kärtner, F. X., Schuman, J. S., and Fujimoto, J. G., "Ultrahighresolution ophthalmic optical coherence tomography," Nat. Med. 7(4), 502-507 (2001).
7. Fercher, A. F., Hitzenberger, C. K., Kamp, G., and El-Zaiat, S. Y., "Measurement of intraocular distances by backscattering spectral interferometry," Opt. Commun. 117, 43-48 (1995).
8. Häusler, G. and Lindner, M. W., "Coherence Radar" and "Spectral Radar"-New Tools for Dermatological Diagnosis," J. Biomed. Opt. 3, 21-31 (Jan. 1998).
9. Haberland, U., Jansen, P., Blazek, V., and Schmitt, H. J., "Optical coherence tomography of scattering media using frequency-modulated continuous-wave techniques with tunable near-infrared laser," in Coherence Domain Optical Methods in Biomedical Science and Clinical Applications, Proc. SPIE 2981, 20-28 (1997).
10. Chinn, S. R., Swanson, E. A., and Fujimoto, J. G., "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22(5), 340-342 (1997).
11. Wojtkowski, M., Srinivasan, V., Ko, T., Fujimoto, J., Kowalczyk, A., and Duker, J., "Ultrahigh-resolution, high-speed, fourier domain optical coherence tomography and methods for dispersion compensation," Opt. Express 12(11), 2404-2422 (2004).
12. Cense, B., Nassif, N., Chen, T., Pierce, M., Yun, S.-H., Park, B., Bouma, B., Tearney, G., and de Boer, J., "Ultrahigh-resolution high-speed retinal imaging using spectral-domain optical coherence tomography," Opt. Express 12(11), 2435-2447 (2004).
13. Huber, R., Adler, D. C., Srinivasan, V. J., and Fujimoto, J. G., "Fourier domain mode locking at 1050 nm for ultra-high-speed optical coherence tomography of the human retina at 236,000 axial scans per second," Opt. Lett. 32(14), 2049-2051 (2007).
14. Srinivasan, V. J., Adler, D. C., Chen, Y., Gorczynska, I., Huber, R., Duker, J., Schuman, J. S., and Fujimoto, J. G., "Ultrahigh-speed Optical Coherence Tomography for Three-Dimensional and En Face Imaging of the Retina and Optic Nerve Head," Invest. Ophthalmol. Vis. Sci., iovs.08-2127 (2008).
15. Srinivasan, V. J., Huber, R., Gorczynska, I., Fujimoto, J. G., Jiang, J. Y., Reisen, P., and Cable, A. E., "High-speed, high-resolution optical coherence tomography retinal imaging with a frequency-swept laser at 850 nm," Opt. Lett. 32(4), 361-363 (2007).
16. Unterhuber, A., Považay, B., Hermann, B., Sattmann, H., Chavez-Pirson, A., and Drexler, W., "In vivo retinal optical coherence tomography at 1040 nm - enhanced penetration into the choroid," Opt. Express 13(9), 3252-3258 (2005).
17. Yasuno, Y., Hong, Y., Makita, S., Yamanari, M., Akiba, M., Miura, M., and Yatagai, T., "In vivo highcontrast imaging of deep posterior eye by 1-um swept source optical coherence tomography andscattering optical coherence angiography," Opt. Express 15(10), 6121-6139 (2007).
18. Nassif, N., Cense, B., Park, B., Pierce, M., Yun, S., Bouma, B., Tearney, G., Chen, T., and de Boer, J., "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12(3), 367-376 (2004).
19. Jiao, S., Knighton, R., Huang, X., Gregori, G., and Puliafito, C., "Simultaneous acquisition of sectional and fundus ophthalmic images with spectral-domain optical coherence tomography," Opt. Express 13(2), 444-452 (2005).
20. Zhang, Y., Cense, B., Rha, J., Jonnal, R. S., Gao, W., Zawadzki, R. J., Werner, J. S., Jones, S., Olivier, S., and Miller, D. T., "High-speed volumetric imaging of cone photoreceptors with adaptive optics spectraldomain optical coherence tomography," Opt. Express 14(10), 4380-4394 (2006).
21. Srinivasan, V. J., Monson, B. K., Wojtkowski, M., Bilonick, R. A., Gorczynska, I., Chen, R., Duker, J. S., Schuman, J. S., and Fujimoto, J. G., "Characterization of Outer Retinal Morphology with High- Speed, Ultrahigh-Resolution Optical Coherence Tomography," Invest. Ophthalmol. Vis. Sci. 49(4), 1571-1579 (2008).
22. Helmers, H. and Schellenberg, M., "CMOS vs. CCD sensors in speckle interferometry," Opt. Laser Technol. 35, 587-595 (2003).
23. Potsaid, B., Gorczynska, I., Srinivasan, V. J., Chen, Y., Jiang, J., Cable, A., and Fujimoto, J. G., "Ultrahigh speed spectral / fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second," Opt. Express 16(19), 15149-15169 (2008).
24. Donnelly III, W. J. and Roorda, A., "Optimal pupil size in the human eye for axial resolution," J. Opt. Soc. Am. A 20(11), 2010-2015 (2003).
25. Hu, Z., Pan, Y., and Rollins, A. M., "Analytical model of spectrometer-based two-beam spectral interferometry," Appl. Opt. 46(35), 8499-8505 (2007).
26. Bajraszewski, T., Wojtkowski, M., Szkulmowski, M., Szkulmowska, A., Huber, R., and Kowalczyk, A., "Improved spectral optical coherence tomography using optical frequency comb," Opt. Express 16(6), 4163-4176 (2008).
27. American National Standards Institute, "American national standard for safe use of lasers, ANSI Z136.1," (2000).
28. Pircher, M., Gotzinger, E., and Hitzenberger, C. K., "Dynamic focus in optical coherence tomography for retinal imaging," J. Biomed. Opt. 11(5), 054013 (2006).
29. Albon, J., Purslow, P. P., Karwatowski, W. S. S., and Easty, D. L., "Age related compliance of the lamina cribrosa in human eyes," Br. J. Ophthalmol 84(3), 318-323 (2000).
30. Vilupuru, A. S., Rangaswamy, N. V., Frishman, L. J., Smith III, E. L., Harwerth, R. S., and Roorda, A., "Adaptive optics scanning laser ophthalmoscopy for in vivo imaging of lamina cribrosa," J. Opt. Soc. Am. A 24(5), 1417-1425 (2007).
31. Pircher, M., Baumann, B., Götzinger, E., and Hitzenberger, C. K., "Retinal cone mosaic imaged with transverse scanning optical coherence tomography," Opt. Lett. 31(12), 1821-1823 (2006).
32. Nelson, D. A., Krupsky, S., Pollack, A., Aloni, E., and Belkin, M., "Special report: Noninvasive multiparameter functional optical imaging of the eye," Ophthalmic Surg. Lasers Imaging 36(1), 57-66 (2005).
33. Martin, J. A. and Roorda, A., "Direct and noninvasive assessment of parafoveal capillary leukocyte velocity," Ophthalmology 112, 2219-2224 (Dec. 2005).