Sequential therapy for the locally advanced larynx and hypopharynx cancer subgroup in TAX 324: Survival, surgery, and organ preservation

Annals of Oncology

Volumn 20, Issue 5, 2009, Pages 921-927

  Posner, Marshall R ^a   Norris, C M ^a   Wirth, L J ^a   Shin, D M ^b   Cullen, K J ^c   Winquist, E W ^d   Blajman, C R ^e   Mickiewicz, E A ^f   Frenette, G P ^g   Plinar, L F ^h   Cohen, R B ⁱ   Steinbrenner, L M ^j   Freue, J M ^k   Gorbunova, V A ^l   Tjulandin, S A ^l   Raez, L E ^m   Adkins, D R ⁿ   Tishler, R B ^o   Roessner, M R ^p   Haddad, R I ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d LONDON REGIONAL CANCER PROGRAM   (Canada)

^e Hospital JBIturraspe Santa Fe   (Argentina)

^f Instituto 'Angel H Roffo'   (Argentina)

^g CAROLINAS MEDICAL CENTER   (United States)

^h RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

ⁱ UNIVERSITY OF VIRGINIA   (United States)

^j VA WESTERN NEW YORK HEALTHCARE SYSTEM   (United States)

^k Hospital Evita   (Argentina)

^l N N BLOKHIN RUSSIAN CANCER RESEARCH CENTER   (Russian Federation)

^m UNIVERSITY OF MIAMI   (United States)

ⁿ WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^o BRIGHAM AND WOMEN S HOSPITAL   (United States)

^p SANOFI   (France)

more..

Author keywords

Chemoradiotherapy; Chemotherapy; Head and neck cancer; Hypopharynx cancer; Larynx cancer; Organ preservation

Indexed keywords

CARBOPLATIN; CISPLATIN; DOCETAXEL; FLUOROURACIL;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; HEAD AND NECK SURGERY; HUMAN; HYPOPHARYNX CANCER; LARYNX CANCER; MAJOR CLINICAL STUDY; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 65549101128     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdn752     Document Type: Article

References (19)

1. Jemal A, Siegel R, Ward E et al. Cancer statistics. CA Cancer J Clin 2008; 58: 71-96.
2. Lefebvre J, Horiot J, Rolland F et al. Phase III study on larynx preservation comparing induction chemotherapy and radiotherapy versus alternating chemoradiotherapy in resectable hypopharynx and larynx cancers. EORTC protocol 24954-22950. J Clin Oncol 2007; 25 (Suppl): 303S(Abstr LBA 6016).
3. Calais G, Pointreau Y, Alfonsi M et al. Randomized phase III trial comparing induction chemotherapy using cisplatin, fluorouracil with or without docetaxel for organ preservation in hypopharynx and larynx cancer. Preliminary results of GORTEC 2000-01. J Clin Oncol 2006; 24 (Suppl): 281S(Abstr 5506).
4. Carvalho AL, Nishimoto IN, Califano JA et al. Trends in incidence and prognosis for head and neck cancer in the United States: A site-specific analysis of the SEER database. Int J Cancer 2005; 114: 806-816.
5. Brockstein B, Haraf DJ, Rademaker AW et al. Patterns of failure, prognostic factors and survival in locoregionally advanced head and neck cancer treated with concomitant chemoradiotherapy: A 9-year, 337-patient, multi-institutional experience. Ann Oncol 2004; 15: 1179-1186.
6. Garden AS. Organ preservation for carcinoma of the larynx and hypopharynx. Hematol Oncol Clin North Am 2001; 15: 243-261.
7. Lefebvre J, Chevalier D, Luboinski B et al. Larynx preservation in pyriform sinus cancer: Preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. J Natl Cancer Inst 1996; 88: 890-898.
8. Semrau R, Mueller RP, Stuetzer H et al. Efficacy of intensified hyperfractionated and accelerated radiotherapy and concurrent chemotherapy with carboplatin and 5-fluorouracil: Updated results of a randomized multicentric trial in advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 2006; 64: 1308-1316.
9. Forastiere A, Maor M, Weber R et al. Long-term results of Intergroup RTOG 91-11: A Phase III trial to preserve the larynx - Induction cisplatin/5-FU and radiation therapy versus concurrent cisplatin and radiation therapy versus radiation therapy. J Clin Oncol 2006; 24 (Suppl): 284S(Abstr 5517).
10. Lefebvre J, Chevalier D, Luboinski B et al. Is laryngeal preservation with induction chemotherapy safe in the treatment of hypopharyngeal SCC? Final results of the Phase III EORTC 24891. Proc Am Soc Clin Oncol 2004; 23 (Suppl): 495S(Abstr 5531).
11. Veterans Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med 1991; 324: 1685-1689.
12. Domenge C, Hill C, Lefebvre J et al. Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma. Br J Cancer 2000; 83: 1594-1598.
13. Pignon J, Bourhis J, Domenge C et al. Chemotherapy added to locoregional treatment for head and neck squamous-cell cancer: Three meta-analysis of updated individual data. Lancet 2000; 355: 949-955.
14. Zorat PL, Paccagnella A, Cavaniglia G et al. Randomized phase III trial of neoadjuvant chemotherapy in head and neck cancer: 10-year follow-up. J Natl Cancer Inst 2004; 96: 1714-1717.
15. Posner MR, Hershock DM, Blajman CR et al. Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. N Engl J Med 2007; 357: 1705-1715.
16. Vermorken JB, Remenar E, van Herpen C et al. Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer. N Engl J Med 2007; 357: 1695-1704.
17. Forastiere A, Pajak T, Maor M et al. Correction to Forastiere et al., N Engl J Med 349:2091-2098, November 27, 2003. N Engl J Med 2004; 350: 1049-1053.
18. Taylor S, Murthy A, Vannetzel J et al. Randomized comparison of neoadjuvant cisplatin and fluorouracil infusion followed by radiation versus concomitant treatment in advanced head and neck cancer. J Clin Oncol 1994; 12: 385-395.
19. Posner MR. Paradigm shift in the treatment of head and neck cancer: The role of neoadjuvant chemotherapy. Oncologist 2005; 10 (Suppl 3): 11-19.