Non-invasive imaging of acute renal allograft rejection in rats using small animal 18F-FDG-PET

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  Reuter, Stefan ^a   Schnöckel, Uta ^a   Schröter, Rita ^a   Schober, Otmar ^a   Pavenstädt, Hermann ^a   Schäfers, Michael ^a   Gabriëls, Gert ^a   Schlatter, Eberhard ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18; DIAGNOSTIC AGENT;

ACUTE GRAFT REJECTION; ACUTE KIDNEY TUBULE NECROSIS; ALLOTRANSPLANTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; EARLY DIAGNOSIS; HISTOPATHOLOGY; IN VIVO STUDY; INFLAMMATORY INFILTRATE; KIDNEY ALLOGRAFT REJECTION; KIDNEY PARENCHYMA; KIDNEY TRANSPLANTATION; NEPHROTOXICITY; NON INVASIVE MEASUREMENT; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; ANIMAL; GRAFT REJECTION; IMMUNOLOGY; KIDNEY; LEWIS RAT; MALE; METHODOLOGY; PATHOLOGY; RAT STRAIN; SCINTISCANNING;

ANIMALIA; RATTUS;

ANIMALS; FLUORODEOXYGLUCOSE F18; GRAFT REJECTION; KIDNEY; KIDNEY TRANSPLANTATION; MALE; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, INBRED LEW; RATS, INBRED STRAINS; TRANSPLANTATION, HOMOLOGOUS;

EID: 65449189755     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005296     Document Type: Article

References (33)

1. Xue JL, Ma JZ, Louis TA, Collins AJ (2001) Forecast of the number of patients with end-stage renal disease in the United States to the year 2010. J Am Soc Nephrol 12: 2753-2758.
2. Opelz G, Dohler B (2008) Influence of Time of Rejection on Long-Term Graft Survival in Renal Transplantation. Transplantation 85: 661-666.
3. Matas AJ, Gillingham KJ, Payne WD, Najarian JS (1994) The impact of an acute rejection episode on long-term renal allograft survival (t1/2). Transplantation 57: 857-859.
4. Meier-Kriesche HU, Ojo AO, Hanson JA, Cibrik DM, Punch JD, Leichtman AB, et al. (2000) Increased impact of acute rejection on chronic allograft failure in recent era. Transplantation 70: 1098-1100.
5. Massy ZA, Guijarro C, Wiederkehr MR, Ma JZ, Kasiske BL (1996) Chronic renal allograft rejection: immunologic and nonimmunologic risk factors. Kidney Int 49: 518-524.
6. Chapman JR, O'Connell PJ, Nankivell BJ (2005) Chronic renal allograft dysfunction. J Am Soc Nephrol 16: 3015-3026.
7. Hariharan S, Johnson CP, Bresnahan BA, Taranto SE, McIntosh MJ, et al. (2000) Improved graft survival after renal transplantation in the United States, 1988 to 1996. N Engl J Med 342: 605-612.
8. Fischer T, Filimonow S, Dieckhofer J, Slowinski T, Muhler M, et al. (2006) Improved diagnosis of early kidney allograft dysfunction by ultrasound with echo enhancer-a new method for the diagnosis of renal perfusion. Nephrol Dial Transplant 21: 2921-2929.
9. Kirkpantur A, Yilmaz R, Baydar DE, Aki T, Cil B, et al. (2008) Utility of the Doppler ultrasound parameter, resistive index, in renal transplant histopathology. Transplant Proc 40: 104-106.
10. Heaf JG, Iversen J (2000) Uses and limitations of renal scintigraphy in renal transplantation monitoring. Eur J Nucl Med 27: 871-879.
11. Dubovsky EV, Russell CD, Bischof-Delaloye A, Bubeck B, Chaiwatanarat T, et al. (1999) Report of the Radionuclides in Nephrourology Committee for evaluation of transplanted kidney (review of techniques). Semin Nucl Med 29: 175-188.
12. Racusen LC, Solez K, Colvin RB, Bonsib SM, Castro MC, et al. (1999) The Banff 97 working classification of renal allograft pathology. Kidney Int 55: 713-723.
13. Rush D (2006) Protocol transplant biopsies: an underutilized tool in kidney transplantation. Clin J Am Soc Nephrol 1: 138-143.
14. Schwarz A, Hiss M, Gwinner W, Becker T, Haller H, et al. (2008) Course and relevance of arteriovenous fistulas after renal transplant biopsies. Am J Transplant 8: 826-831.
15. El-Mekresh M, Osman Y, li-El-Dein B, El-Diasty T, Ghoneim MA (2001) Urological complications after living-donor renal transplantation. BJU Int 87: 295-306.
16. Gallon L, Gagliardini E, Benigni A, Kaufman D, Waheed A, et al. (2006) Immunophenotypic analysis of cellular infiltrate of renal allograft biopsies in patients with acute rejection after induction with alemtuzumab (Campath-1H). Clin J Am Soc Nephrol 1: 539-545.
17. Sarwal M, Chua MS, Kambham N, Hsieh SC, Satterwhite T, et al. (2003) Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling. N Engl J Med 349: 125-138.
18. Pellegrino D, Bonab AA, Dragotakes SC, Pitman JT, Mariani G, et al. (2005) Inflammation and infection: imaging properties of 18F-FDG-labeled white blood cells versus 18F-FDG. J Nucl Med 46: 1522-1530.
19. Bos R, van Der Hoeven JJ, van Der WE, van Der GP, van Diest PJ, et al. (2002) Biologic correlates of (18)fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography. J Clin Oncol 20: 379-387.
20. Kaim AH, Weber B, Kurrer MO, Gottschalk J, Von Schulthess GK, et al. (2002) Autoradiographic quantification of 18F-FDG uptake in experimental soft-tissue abscesses in rats. Radiology 223: 446-451.
21. Solez K, Colvin RB, Racusen LC, Haas M, Sis B, et al. (2008) Banff 07 classification of renal allograft pathology: updates and future directions. Am J Transplant 8: 753-760.
22. Broekema M, Harmsen MC, van Luyn MJ, Koerts JA, Petersen AH, et al. (2007) Bone marrow-derived myofibroblasts contribute to the renal interstitial myofibroblast population and produce procollagen I after ischemia/reperfusion in rats. J Am Soc Nephrol 18: 165-175.
23. Hanley JA, McNeil BJ (1982) The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 143: 29-36.
24. Schnöckel U, Reuter S, Stegger L, Schlatter E, Schafers KP, et al. (2008) Dynamic (18)F-fluoride small animal PET to noninvasively assess renal function in rats. Eur J Nucl Med Mol Imaging 35: 2267-2274.
25. Sis B, Sarioglu S, Celik A, Kasap B, Yildiz S, et al. (2006) Renal medullary changes in renal allograft recipients with raised serum creatinine. J Clin Pathol 59: 377-381.
26. Blodgett TM, Meltzer CC, Townsend DW (2007) PET/CT: form and function. Radiology 242: 360-385.
27. Meller J, Sahlmann CO, Scheel AK (2007) 18F-FDG PET and PET/CT in fever of unknown origin. J Nucl Med 48: 35-45.
28. Velic A, Hirsch JR, Bartel J, Thomas R, Schröter R, et al. (2004) Renal transplantation modulates expression and function of receptors and transporters of rat proximal tubules. J Am Soc Nephrol 15: 967-977.
29. Velic A, Gabriëls G, Hirsch JR, Schröter R, Edemir B, et al. (2005) Acute rejection after rat renal transplantation leads to downregulation of NA+ and water channels in the collecting duct. Am J Transplant 5: 1276-1285.
30. Gabriëls G, August C, Grisk O, Steinmetz M, Kosch M, et al. (2003) Impact of renal transplantation on small vessel reactivity. Transplantation 75: 689-697. 10.1097/01.TP.0000044111.12370.ED [doi].
31. Reuter S, Velic A, Edemir B, Schröter R, Pavenstädt H, et al. (2008) Protective role of NHE-3 inhibition in rat renal transplantation undergoing acute rejection. Pflugers Arch 456: 1075-1084.
32. Kim K, Kim SH, Yang CW, Li C, Chung YA, et al. (2003) Differentiation between acute cyclosporine nephrotoxicity and acute tubular necrosis using enalaprilat renal scintigraphy in rats. Invest Radiol 38: 473-481.
33. Schäfers KP, Reader AJ, Kriens M, Knoess C, Schober O, et al. (2005) Performance evaluation of the 32-module quadHIDAC small-animal PET scanner. J Nucl Med 46: 996-1004.