CTIP2 expression in human head and neck squamous cell carcinoma is linked to poorly differentiated tumor status

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  Ganguli Indra, Gitali ^a   Wasylyk, Christine ^c,d   Liang, Xiaobo ^a   Millon, Regine ^b   Leid, Mark ^a   Wasylyk, Bohdan ^c,d   Abecassis, Joseph ^b   Indra, Arup ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b CENTRE PAUL STRAUSS   (France)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR INTERACTING PROTEIN 2; COMPLEMENTARY DNA; PROTEIN CTIP2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; BCL11B PROTEIN, HUMAN; BMI1 PROTEIN, HUMAN; DNA; DNA BINDING PROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; ONCOPROTEIN; PRIMER DNA; REPRESSOR PROTEIN; RNA; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN;

ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER STAGING; CANCER STEM CELL; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIUM; HEAD AND NECK CARCINOMA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; STAINING; WESTERN BLOTTING; CELL DIFFERENTIATION; GENE EXPRESSION; GENETICS; HEAD AND NECK TUMOR; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; TUMOR CELL LINE;

MUS;

BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; CELL DIFFERENTIATION; CELL LINE, TUMOR; DNA PRIMERS; DNA, NEOPLASM; DNA-BINDING PROTEINS; GENE EXPRESSION; HEAD AND NECK NEOPLASMS; HUMANS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 65449184521     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005367     Document Type: Article

References (42)

1. Ahmedin Jemal RS, Elizabeth Ward, Yongping Hao, Jiaquan Xu, Taylor Murray, Michael J Thun (2008) Cancer statistics. CA Cancer J Clin 2008 58: 71-96.
2. Marur S, Forastiere AA (2008) Head and neck cancer: changing epidemiology, diagnosis, and treatment. Mayo Clin Proc 83: 489-501.
3. Spitz MR (1994) Epidemiology and risk factors for head and neck cancer. Semin Oncol 21: 281-288.
4. Forastiere A, Koch W, Trotti A, Sidransky D (2001) Head and neck cancer. N Engl J Med 345: 1890-1900.
5. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, et al. (2005) Cancer statistics, 2005. CA Cancer J Clin 55: 10-30.
6. Patel V, Leethanakul C, Gutkind JS (2001) New approaches to the understanding of the molecular basis of oral cancer. Crit Rev Oral Biol Med 12: 55-63.
7. Friedlander PL (2003) The use of genetic markers in the clinical care of patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 129: 363-366.
8. Rodrigo JP, Suarez C, Ferlito A, Devaney KO, Petruzzelli GJ, et al. (2003) Potential molecular prognostic markers for lymph node metastasis in head and neck squamous cell carcinoma. Acta Otolaryngol 123: 100-105.
9. Schliephake H (2003) Prognostic relevance of molecular markers of oral cancer - a review. Int J Oral Maxillofac Surg 32: 233-245.
10. Chang SS, Califano J (2008) Current status of biomarkers in head and neck cancer. J Surg Oncol 97: 640-643.
11. Avram D, Fields A, Pretty On Top K, Nevrivy DJ, Ishmael JE, et al. (2000) Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. J Biol Chem 275: 10315-10322.
12. Avram D, Fields A, Senawong T, Topark-Ngarm A, Leid M (2002) COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein. Biochem J 368: 555-563.
13. Cismasiu VB, Adamo K, Gecewicz J, Duque J, Lin Q, et al. (2005) BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter. Oncogene 24: 6753-6764.
14. Topark-Ngarm A, Golonzhka O, Peterson VJ, Barrett B Jr, Martinez B, et al. (2006) CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene. J Biol Chem 281: 32272-32283.
15. Wakabayashi Y, Watanabe H, Inoue J, Takeda N, Sakata J, et al. (2003) Bcl11b is required for differentiation and survival of alphabeta T lymphocytes. Nat Immunol 4: 533-539.
16. Senawong T, Peterson VJ, Leid M (2005) BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression. Arch Biochem Biophys 434: 316-325.
17. Przybylski GK, Dik WA, Wanzeck J, Grabarczyk P, Majunke S, et al. (2005) Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL. Leukemia 19: 201-208.
18. Satterwhite E, Sonoki T, Willis TG, Harder L, Nowak R, et al. (2001) The BCL11 gene family: involvement of BCL11A in lymphoid malignancies. Blood 98: 3413-3420.
19. Golonzhka O, Leid M, Indra G, Indra AK (2007) Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood. Gene Expr Patterns 7: 754-760.
20. Leid M, Ishmael JE, Avram D, Shepherd D, Fraulob V, et al. (2004) CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis. Gene Expr Patterns 4: 733-739.
21. Golonzhka O, Liang X, Messaddeq N, Bornert JM, Campbell AL, et al. (2008) Dual Role of COUP-TF-Interacting Protein 2 in Epidermal Homeostasis and Permeability Barrier Formation. J Invest Dermatol.
22. Dvorak HF (1986) Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 315: 1650-1659.
23. Seghatoleslam A, Zambrano A, Millon R, Ganguli G, Argentini M, et al. (2006) Analysis of a novel human gene, LOC92912, over-expressed in hypopharyngeal tumours. Biochem Biophys Res Commun 339: 422-429.
24. Indra AK, Mohan WS 2nd, Frontini M, Scheer E, Messaddeq N, et al. (2005) TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis. Dev Biol 285: 28-37.
25. Nowak K, Kerl K, Fehr D, Kramps C, Gessner C, et al. (2006) BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas. Nucleic Acids Res 34: 1745-1754.
26. Li Y, St John MA, Zhou X, Kim Y, Sinha U, et al. (2004) Salivary transcriptome diagnostics for oral cancer detection. Clin Cancer Res 10: 8442-8450.
27. Lessard J, Sauvageau G (2003) Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423: 255-260.
28. Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, et al. (2003) Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425: 962-967.
29. Park IK, Qian D, Kiel M, Becker MW, Pihalja M, et al. (2003) Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423: 302-305.
30. Chiba T, Miyagi S, Saraya A, Aoki R, Seki A, et al. (2008) The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma. Cancer Res 68: 7742-7749.
31. Dovey JS, Zacharek SJ, Kim CF, Lees JA (2008) Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion. Proc Natl Acad Sci U S A 105: 11857-11862.
32. Glinsky GV (2008) "Stemness" genomics law governs clinical behavior of human cancer: implications for decision making in disease management. J Clin Oncol 26: 2846-2853.
33. Godlewski J, Nowicki MO, Bronisz A, Williams S, Otsuki A, et al. (2008) Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 68: 9125-9130.
34. Mack B, Gires O (2008) CD44s and CD44v6 expression in head and neck epithelia. PLoS ONE 3: e3360.
35. Pietersen AM, Evers B, Prasad AA, Tanger E, Cornelissen-Steijger P, et al. (2008) Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium. Curr Biol 18: 1094-1099.
36. Prince ME, Ailles LE (2008) Cancer stem cells in head and neck squamous cell cancer. J Clin Oncol 26: 2871-2875.
37. Prince ME, Sivanandan R, Kaczorowski A, Wolf GT, Kaplan MJ, et al. (2007) Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci U S A 104: 973-978.
38. Ganguli-Indra G, Liang X, Hyter S, Leid M, Hanifin JM, et al. (2009) Expression of COUP-TF-interacting protein 2 (CTIP2) in human atopic dermatitis and allergic contact dermatitis skin. Exp Dermatol In press.
39. Korkaya H, Wicha MS (2007) Selective targeting of cancer stem cells: a new concept in cancer therapeutics. BioDrugs 21: 299-310.
40. MacLeod RA, Nagel S, Drexler HG (2004) BCL11B rearrangements probably target T-cell neoplasia rather than acute myelocytic leukemia. Cancer Genet Cytogenet 153: 88-89.
41. Kamimura K, Mishima Y, Obata M, Endo T, Aoyagi Y, et al. (2007) Lack of Bcl11b tumor suppressor results in vulnerability to DNA replication stress and damages. Oncogene 26: 5840-5850.
42. Lu SL, Herrington H, Wang XJ (2006) Mouse models for human head and neck squamous cell carcinomas. Head Neck 28: 945-954.