Choosing the road less traveled by: A ligand-receptor system that controls target recognition by drosophila motor axons

Genes and Development

Volumn 23, Issue 9, 2009, Pages 1042-1045

  Zinn, Kai ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Beaten path; Drosophila; In vivo imaging; Motor axon guidance; Sidestep; Substrate pathway; Time lapse movie

Indexed keywords

CELL SURFACE PROTEIN; LIGAND; PROTEIN BEAT; PROTEIN SIDE; UNCLASSIFIED DRUG; BEAT IA PROTEIN, DROSOPHILA; BEAT-IA PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN; SIDESTEP PROTEIN, DROSOPHILA;

DROSOPHILA; GENE CONTROL; HUMAN; MOLECULAR CLONING; MOTOR NERVE; MOTOR PERFORMANCE; NERVE GROWTH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; DROSOPHILA MELANOGASTER; METABOLISM; MOTONEURON; NERVE FIBER; NOTE; PHYSIOLOGY;

ANIMALS; AXONS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; LIGANDS; MEMBRANE PROTEINS; MOTOR NEURONS; NERVE TISSUE PROTEINS; SIGNAL TRANSDUCTION;

EID: 65449182029     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1803009     Document Type: Review

References (10)

1. Fambrough, D. and Goodman, C.S. 1996. The Drosophila beaten path gene encodes a novel secreted protein that regulates defasciculation at motor axon choice points. Cell 87: 1049-1058.
2. Keshishian, H., Broadie, K., Chiba, A., and Bate, M. 1996. The Drosophila neuromuscular junction: A model system for studying synaptic development and function. Annu. Rev. Neurosci. 19: 545-575.
3. Kraut, R., Menon, K., and Zinn, K. 2001. A gain-of-function screen for genes controlling motor axon guidance and syn- aptogenesis in Drosophila. Curr. Biol. 11: 417-430.
4. Landgraf, M. and Thor, S. 2006. Development of Drosophila motoneurons: Specification and morphology. Semin. Cell Dev. Biol. 17: 3-11.
5. Landgraf, M., Baylies, M., and Bate, M. 1999. Muscle founder cells regulate defasciculation and targeting of motor axons in the Drosophila embryo. Curr. Biol. 9: 589-592.
6. Pipes, G.C., Lin, Q., Riley, S.E., and Goodman, C.S. 2001. The Beat generation: A multigene family encoding IgSF proteins related to the Beat axon guidance molecule in Drosophila. Development 128: 4545-4552.
7. Siebert, M., Banovic, D., Goellner, B., and Aberle, H. 2009. Drosophila motor axons recognize and follow a Sidestep- labeled substrate pathway to reach their target fields. Genes & Dev. (this issue). doi: 10.1101/gad.520509.
8. Sink, H., Rehm, E.J., Richstone, L., Bulls, Y.M., and Goodman, C.S. 2001. sidestep encodes a target-derived attractant essential for motor axon guidance in Drosophila. Cell 105:57-67.
9. Vactor, D.V., Sink, H., Fambrough, D., Tsoo, R., and Goodman, C.S. 1993. Genes that control neuromuscular specificity in Drosophila. Cell 73: 1137-1153.
10. Zito, K., Parnas, D., Fetter, R.D., Isacoff, E.Y., and Goodman, C.S. 1999. Watching a synapse grow: Noninvasive confocal imaging of synaptic growth in Drosophila. Neuron 22: 719-729.