Use of a real-time fluorescence monitoring system for high-throughput screening for Prolyl isomerase inhibitors

Journal of Biomolecular Screening

Volumn 14, Issue 4, 2009, Pages 419-424

  Mori, Tadashi ^a,b   Itami, Seima ^b   Yanagi, Tomotaka ^a   Tatara, Yota ^a   Takamiya, Mari ^b   Uchida, Takafumi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Cyclophilin; Cyclosporin A; High throughput screening; Peptidyl prolyl cis trans isomerase; Protease coupled assay

Indexed keywords

CYCLOPHILIN A; CYCLOSPORIN A; CYCLOSPORIN D; CYCLOSPORIN H; ISOMERASE INHIBITOR; PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CONTROLLED STUDY; DEVICE; DRUG MONITORING; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG STRUCTURE; ENZYME INHIBITION; FLUORESCENCE ANALYSIS; HIGH THROUGHPUT SCREENING; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE;

CYCLOPHILINS; ENZYME INHIBITORS; FLUOROMETRY; KINETICS; PEPTIDYLPROLYL ISOMERASE; REPRODUCIBILITY OF RESULTS; SMALL MOLECULE LIBRARIES; SURFACE PLASMON RESONANCE; TIME FACTORS;

EID: 65449163439     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057109333979     Document Type: Article

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