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Volumn 182, Issue 6, 2009, Pages 3432-3439

Functional silencing is initiated and maintained in immature anti-insulin B cells

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; BREAKPOINT CLUSTER REGION PROTEIN; CALCINEURIN; CALCIUM; CD40 ANTIGEN; INSULIN; INSULIN ANTIBODY; INTERLEUKIN 7;

EID: 65449159750     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803121     Document Type: Article
Times cited : (12)

References (36)
  • 1
    • 0032532294 scopus 로고    scopus 로고
    • B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice
    • Serreze, D. V., S. A. Fleming, H. D. Chapman, S. D. Richard, E. H. Leiter, and R. M. Tisch. 1998. B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice. J. Immunol. 161: 3912-3918.
    • (1998) J. Immunol , vol.161 , pp. 3912-3918
    • Serreze, D.V.1    Fleming, S.A.2    Chapman, H.D.3    Richard, S.D.4    Leiter, E.H.5    Tisch, R.M.6
  • 2
    • 0027499537 scopus 로고
    • Receptor editing: An approach by autoreactive B cells to escape tolerance
    • Gay, D., T. Saunders, S. Camper, and M. Weigert. 1993. Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177: 999-1008.
    • (1993) J. Exp. Med , vol.177 , pp. 999-1008
    • Gay, D.1    Saunders, T.2    Camper, S.3    Weigert, M.4
  • 4
    • 0009927162 scopus 로고
    • Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras
    • Nemazee, D., and K. Buerki. 1989. Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras. Proc. Natl. Acad. Sci. USA 86: 8039-8043.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 8039-8043
    • Nemazee, D.1    Buerki, K.2
  • 5
    • 0024529870 scopus 로고
    • Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
    • Nemazee, D. A., and K. Burki. 1989. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes. Nature 337: 562-566.
    • (1989) Nature , vol.337 , pp. 562-566
    • Nemazee, D.A.1    Burki, K.2
  • 6
    • 0027532192 scopus 로고
    • B lymphocytes may escape tolerance by revising their antigen receptors
    • Radic, M. Z., J. Erikson, S. Litwin, and M. Weigert. 1993. B lymphocytes may escape tolerance by revising their antigen receptors. J. Exp. Med. 177: 1165-1173.
    • (1993) J. Exp. Med , vol.177 , pp. 1165-1173
    • Radic, M.Z.1    Erikson, J.2    Litwin, S.3    Weigert, M.4
  • 7
    • 0027478391 scopus 로고
    • Receptor editing in self-reactive bone marrow B cells
    • Tiegs, S. L., D. M. Russell, and D. Nemazee. 1993. Receptor editing in self-reactive bone marrow B cells. J. Exp. Med. 177: 1009-1020.
    • (1993) J. Exp. Med , vol.177 , pp. 1009-1020
    • Tiegs, S.L.1    Russell, D.M.2    Nemazee, D.3
  • 8
    • 0028127965 scopus 로고
    • Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells
    • Cooke, M. P., A. W. Heath, K. M. Shokat, Y. Zeng, F. D. Finkelman, P. S. Linsley, M. Howard, and C. C. Goodnow. 1994. Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells. J. Exp. Med. 179: 425-438.
    • (1994) J. Exp. Med , vol.179 , pp. 425-438
    • Cooke, M.P.1    Heath, A.W.2    Shokat, K.M.3    Zeng, Y.4    Finkelman, F.D.5    Linsley, P.S.6    Howard, M.7    Goodnow, C.C.8
  • 10
    • 0035284755 scopus 로고    scopus 로고
    • Anergy and not clonal ignorance determines the fate of B cells that recognize a physiological autoantigen
    • Rojas, M., C. Hulbert, and J. W. Thomas. 2001. Anergy and not clonal ignorance determines the fate of B cells that recognize a physiological autoantigen. J. Immunol. 166: 3194-3200.
    • (2001) J. Immunol , vol.166 , pp. 3194-3200
    • Rojas, M.1    Hulbert, C.2    Thomas, J.W.3
  • 11
    • 0028064578 scopus 로고
    • Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
    • Cyster, J. G., S. B. Hartley, and C. C. Goodnow. 1994. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. Nature 371: 389-395.
    • (1994) Nature , vol.371 , pp. 389-395
    • Cyster, J.G.1    Hartley, S.B.2    Goodnow, C.C.3
  • 12
    • 27544458293 scopus 로고    scopus 로고
    • Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling
    • Gauld, S. B., R. J. Benschop, K. T. Merrell, and J. C. Cambier. 2005. Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling. Nat. Immunol. 6: 1160-1167.
    • (2005) Nat. Immunol , vol.6 , pp. 1160-1167
    • Gauld, S.B.1    Benschop, R.J.2    Merrell, K.T.3    Cambier, J.C.4
  • 13
    • 0025812171 scopus 로고
    • Breakdown of self-tolerance in anergic B lymphocytes
    • Goodnow, C. C., R. Brink, and E. Adams. 1991. Breakdown of self-tolerance in anergic B lymphocytes. Nature 352: 532-536.
    • (1991) Nature , vol.352 , pp. 532-536
    • Goodnow, C.C.1    Brink, R.2    Adams, E.3
  • 14
    • 0020510712 scopus 로고
    • Mapping epitopes on the insulin molecule using monoclonal antibodies
    • Schroer, J. A., T. Bender, R. J. Feldmann, and K. J. Kim. 1983. Mapping epitopes on the insulin molecule using monoclonal antibodies. Eur. J. Immunol. 13: 693-700.
    • (1983) Eur. J. Immunol , vol.13 , pp. 693-700
    • Schroer, J.A.1    Bender, T.2    Feldmann, R.J.3    Kim, K.J.4
  • 15
    • 33746913510 scopus 로고    scopus 로고
    • Impaired intracellular calcium mobilization and NFATc1 availability in tolerant anti-insulin B cells
    • Acevedo-Suarez, C. A., D. M. Kilkenny, M. B. Reich, and J. W. Thomas. 2006. Impaired intracellular calcium mobilization and NFATc1 availability in tolerant anti-insulin B cells. J. Immunol. 177: 2234-2241.
    • (2006) J. Immunol , vol.177 , pp. 2234-2241
    • Acevedo-Suarez, C.A.1    Kilkenny, D.M.2    Reich, M.B.3    Thomas, J.W.4
  • 16
    • 11844260763 scopus 로고    scopus 로고
    • Uncoupling of anergy from developmental arrest in anti-insulin B cells supports the development of autoimmune diabetes
    • Acevedo-Suarez, C. A., C. Hulbert, E. J. Woodward, and J. W. Thomas. 2005. Uncoupling of anergy from developmental arrest in anti-insulin B cells supports the development of autoimmune diabetes. J. Immunol. 174: 827-833.
    • (2005) J. Immunol , vol.174 , pp. 827-833
    • Acevedo-Suarez, C.A.1    Hulbert, C.2    Woodward, E.J.3    Thomas, J.W.4
  • 17
    • 0026542446 scopus 로고
    • Differential roles of stromal cells, interleukin-7, and kitligand in the regulation of B lymphopoiesis
    • Billips, L. G., D. Petitte, K. Dorshkind, R. Narayanan, C. P. Chiu, and K. S. Landreth. 1992. Differential roles of stromal cells, interleukin-7, and kitligand in the regulation of B lymphopoiesis. Blood 79: 1185-1192.
    • (1992) Blood , vol.79 , pp. 1185-1192
    • Billips, L.G.1    Petitte, D.2    Dorshkind, K.3    Narayanan, R.4    Chiu, C.P.5    Landreth, K.S.6
  • 18
    • 0025110360 scopus 로고
    • The influence of S17 stromal cells and interleukin 7 on B cell development
    • Cumano, A., K. Dorshkind, S. Gillis, and C. J. Paige. 1990. The influence of S17 stromal cells and interleukin 7 on B cell development. Eur. J. Immunol. 20: 2183-2189.
    • (1990) Eur. J. Immunol , vol.20 , pp. 2183-2189
    • Cumano, A.1    Dorshkind, K.2    Gillis, S.3    Paige, C.J.4
  • 20
    • 0035129651 scopus 로고    scopus 로고
    • Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive
    • Benschop, R. J., K. Aviszus, X. Zhang, T. Manser, J. C. Cambier, and L. J. Wysocki. 2001. Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive. Immunity 14: 33-43.
    • (2001) Immunity , vol.14 , pp. 33-43
    • Benschop, R.J.1    Aviszus, K.2    Zhang, X.3    Manser, T.4    Cambier, J.C.5    Wysocki, L.J.6
  • 21
    • 0029006329 scopus 로고
    • Engagement of the antigen-receptor on immature murine B lymphocytes results in death by apoptosis
    • Norvell, A., L. Mandik, and J. G. Monroe. 1995. Engagement of the antigen-receptor on immature murine B lymphocytes results in death by apoptosis. J. Immunol. 154: 4404-4413.
    • (1995) J. Immunol , vol.154 , pp. 4404-4413
    • Norvell, A.1    Mandik, L.2    Monroe, J.G.3
  • 22
    • 0017140683 scopus 로고
    • Anti-immunoglobulin stimulation of murine lymphocytes: I. Age dependency of the proliferative response
    • Weiner, H. L., J. W. Moorhead, and H. N. Claman. 1976. Anti-immunoglobulin stimulation of murine lymphocytes: I. Age dependency of the proliferative response. J. Immunol. 116: 1656-1661.
    • (1976) J. Immunol , vol.116 , pp. 1656-1661
    • Weiner, H.L.1    Moorhead, J.W.2    Claman, H.N.3
  • 23
    • 0026743070 scopus 로고
    • Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen
    • Brink, R., C. C. Goodnow, J. Crosbie, E. Adams, J. Eris, D. Y. Mason, S. B. Hartley, and A. Basten. 1992. Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen. J. Exp. Med. 176: 991-1005.
    • (1992) J. Exp. Med , vol.176 , pp. 991-1005
    • Brink, R.1    Goodnow, C.C.2    Crosbie, J.3    Adams, E.4    Eris, J.5    Mason, D.Y.6    Hartley, S.B.7    Basten, A.8
  • 24
    • 0027435255 scopus 로고
    • Polyclonal activation of immature B cells by preactivated T cells: The role of IL-4 and CD40 ligand
    • Brines, R. D., and G. G. Klaus. 1993. Polyclonal activation of immature B cells by preactivated T cells: the role of IL-4 and CD40 ligand. Int. Immunol. 5: 1445-1450.
    • (1993) Int. Immunol , vol.5 , pp. 1445-1450
    • Brines, R.D.1    Klaus, G.G.2
  • 26
    • 0032100706 scopus 로고    scopus 로고
    • Affinity dependence of the B cell response to antigen: A threshold, a ceiling, and the importance of off-rate
    • Batista, F. D., and M. S. Neuberger. 1998. Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate. Immunity 8: 751-759.
    • (1998) Immunity , vol.8 , pp. 751-759
    • Batista, F.D.1    Neuberger, M.S.2
  • 27
    • 0035958618 scopus 로고    scopus 로고
    • Role of receptor editing and revision in shaping the B and T lymphocyte repertoire
    • Kouskoff, V., and D. Nemazee. 2001. Role of receptor editing and revision in shaping the B and T lymphocyte repertoire. Life Sci. 69: 1105-1113.
    • (2001) Life Sci , vol.69 , pp. 1105-1113
    • Kouskoff, V.1    Nemazee, D.2
  • 28
    • 3843100621 scopus 로고    scopus 로고
    • The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells
    • Meade, J., V. L. Tybulewicz, and M. Turner. 2004. The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells. Eur. J. Immunol. 34: 1102-1110.
    • (2004) Eur. J. Immunol , vol.34 , pp. 1102-1110
    • Meade, J.1    Tybulewicz, V.L.2    Turner, M.3
  • 29
    • 0036604452 scopus 로고    scopus 로고
    • Impaired light chain allelic exclusion and lack of positive selection in immature B cells expressing incompetent receptor deficient of CD19
    • Shivtiel, S., N. Leider, O. Sadeh, Z. Kraiem, and D. Melamed. 2002. Impaired light chain allelic exclusion and lack of positive selection in immature B cells expressing incompetent receptor deficient of CD19. J. Immunol. 168: 5596-5604.
    • (2002) J. Immunol , vol.168 , pp. 5596-5604
    • Shivtiel, S.1    Leider, N.2    Sadeh, O.3    Kraiem, Z.4    Melamed, D.5
  • 32
    • 0347949547 scopus 로고    scopus 로고
    • Regulation of cell cycle progression by calcium/calmodulin-dependent pathways
    • Kahl, C. R., and A. R. Means. 2003. Regulation of cell cycle progression by calcium/calmodulin-dependent pathways. Endocr. Rev. 24: 719-736.
    • (2003) Endocr. Rev , vol.24 , pp. 719-736
    • Kahl, C.R.1    Means, A.R.2
  • 33
    • 77949443136 scopus 로고    scopus 로고
    • Felig, P. 1983. Physiologic action of insulin. In Diabetes Mellitus, Theory and Practice. M. Ellenberg and H. Rifkin, eds. Medical Examination Publishing, New Hyde Park, pp. 77-88.
    • Felig, P. 1983. Physiologic action of insulin. In Diabetes Mellitus, Theory and Practice. M. Ellenberg and H. Rifkin, eds. Medical Examination Publishing, New Hyde Park, pp. 77-88.
  • 34
    • 77956751025 scopus 로고
    • Insulin: The structure in the crystal and its reflection in chemistry and biology
    • C. B. Anfinsen, J. T. Edsall, and F. M. Richards, eds. Academic, New York, pp
    • Blundell, T., G. Dodson, D. Hodgkin, and D. Mercola. 1972. Insulin: the structure in the crystal and its reflection in chemistry and biology. In Advances in Protein Chemistry, Vol. 26. C. B. Anfinsen, J. T. Edsall, and F. M. Richards, eds. Academic, New York, pp. 279-403.
    • (1972) Advances in Protein Chemistry , vol.26 , pp. 279-403
    • Blundell, T.1    Dodson, G.2    Hodgkin, D.3    Mercola, D.4
  • 35
    • 0033822263 scopus 로고    scopus 로고
    • Immunobiology of the immature B cell: Plasticity in the B-cell antigen receptor-induced response fine tunes negative selection
    • King, L. B., and J. G. Monroe. 2000. Immunobiology of the immature B cell: plasticity in the B-cell antigen receptor-induced response fine tunes negative selection. Immunol. Rev. 176: 86-104.
    • (2000) Immunol. Rev , vol.176 , pp. 86-104
    • King, L.B.1    Monroe, J.G.2
  • 36
    • 39149094629 scopus 로고    scopus 로고
    • Insulin as an autoantigen in NOD/human diabetes
    • Zhang, L., M. Nakayama, and G. S. Eisenbarth. 2008. Insulin as an autoantigen in NOD/human diabetes. Curr. Opin. Immunol. 20: 111-118.
    • (2008) Curr. Opin. Immunol , vol.20 , pp. 111-118
    • Zhang, L.1    Nakayama, M.2    Eisenbarth, G.S.3


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