Substrate utilization during and after exercise in mild cystic fibrosis

Medicine and Science in Sports and Exercise

Volumn 41, Issue 2, 2009, Pages 270-278

  Wideman, L ^a   Baker, Carol F ^a   Brown, Pam Kocher ^a   Consitt, Leslie A ^a   Ambrosius, Walter T ^b   Schechter, Michael S ^b  

^a UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Cystic fibrosis; Energy expenditure; Maximal exercise; RQ; Submaximal exercise

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BODY MASS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; ENERGY EXPENDITURE; EXERCISE; FEMALE; HEART RATE; HUMAN; MALE; OXYGEN CONSUMPTION; SCHOOL CHILD; CASE CONTROL STUDY; ENERGY METABOLISM; EXERCISE TOLERANCE; FITNESS; LUNG FUNCTION TEST; METABOLISM; PHYSIOLOGY;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CYSTIC FIBROSIS; ENERGY METABOLISM; EXERCISE TOLERANCE; FEMALE; HUMANS; MALE; OXYGEN CONSUMPTION; PHYSICAL FITNESS; RESPIRATORY FUNCTION TESTS; YOUNG ADULT;

EID: 65449159301     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0b013e318188449b     Document Type: Article

References (50)

1. Allen JR, McCauley JC, Selby AM, et al. Differences in resting energy expenditure between male and female children with cystic fibrosis. J Pediatr. 2003;142:15-9.
2. Barker M, Hebestreit A, Gruber W, Hebestreit H. Exercise testing and training in German CF centers. Pediatr Pulmonol. 2004;37:351-5.
3. Bouchard C, Dionne F, Simoneau JA, Boulay MR. Genetics of aerobic and anaerobic performances. Exerc Sport Sci Rev. 1992;20:27-58.
4. Boucher G, Lands L, Hay J, Hornby L. Activity levels and the relationship to lung function and nutritional status in children with cystic fibrosis. Am J Phys Med Rehabil. 1997;76:311-5.
5. Britto MT, Garrett JM, Konrad TR, Majure JM, Leigh MW. Comparison of physical activity in adolescents with cystic fibrosis versus age-matched controls. Pediatr Pulmonol. 2000;30:86-91.
6. Brooks G, Mercier J. Balance of carbohydrate and lipid utilization during exercise: the crossover concept. J Appl Physiol. 1994;76(6):2253-61.
7. de Jong W, Grevink RG, Roorda RJ, Kaptein AA, van der Schans C. Effect of a home exercise training program in patients with cystic fibrosis. Chest. 1994;105(5):463-8.
8. de Meer K, Jeneson JA, Gulmans VAM, van der Laag J, Berger R. Efficiency of oxidative work performance of skeletal muscle in patients with cystic fibrosis. Thorax. 1995;50:980-3.
9. Dodd JD, Barry SC, Gallagher CG. Respiratory factors do not limit maximal symptom-limited exercise in patients with mild cystic fibrosis lung disease. Respir Physiol Neurobiol. 2006;152:176-85.
10. Godfrey S. Exercise Training in Children. London: W.B. Saunders Co. Ltd.; 1974. p. 30.
11. Grunow J, Azcue M, Berall G, Pencharz P. Energy expenditure in cystic fibrosis during activities of daily living. J Pediatr. 1993;122(2):243-6.
12. Hebestreit H, Hebestreit A, Trusen A, Hughson RL. Oxygen uptake kinetics are slowed in cystic fibrosis. Med Sci Sports Exerc. 2005;37(1):10-7.
13. 1 in cystic fibrosis? Arch Dis Child. 2005;90:792-5.
14. Johnson MR, Ferkol TW, Shepherd RW. Energy cost of activity and exercise in children and adolescents with cystic fibrosis. J Cyst Fibros. 2006;5(1):53-8.
15. Keochkerian D, Chlif M, Delanaud S, Gauthier R, Maingourd Y, Ahmaidi S. Timing and driving components of the breathing strategy in children with cystic fibrosis during exercise. Pediatr Pulmonol. 2005;40:449-56.
16. Lees CM, Smyth RL. The current management of cystic fibrosis. Int J Clin Pract. 2000;54(3):171-9.
17. Loutzenhiser JK, Clark R. Physical activity and exercise in children with cystic fibrosis. J Pediatr Nurs. 1993;8(2):112-9.
18. Marcotte JE, Grisdale RK, Levison H, Coates AL, Canny GJ. Multiple factors limit exercise capacity in cystic fibrosis. Pediatr Pulmonol. 1986;9:974-81.
19. Marin V, Velandia S, Hunter B, et al. Energy expenditure, nutrition status, and body composition in children with cystic fibrosis. Nutrition. 2004;20:181-6.
20. McArdle WD, Katch FI, Katch VL. Exercise Physiology; Energy, Nutrition, & Human Performance. Baltimore (MA): Lippincott Williams & Wilkins; 2007. p. 192.
21. McIlwaine M, Davidson A. Airway clearance techniques in the treatment of cystic fibrosis. J Pediatr. 1996;2:447-51.
22. Moorcroft A, Dodd M, Morris J, Webb A. Individualised unsupervised exercise training in adults with cystic fibrosis: a 1 year randomised controlled trial. Thorax. 2004;59:1074-80.
23. Moorcroft A, Dodd M, Webb A. Exercise testing and prognosis in adult cystic fibrosis. Thorax. 1997;52:291-3.
24. Morris NM, Udry JR. Validation of a self-administered instument to assess stage of adolescent development. J Youth Adolesc. 1980;9(3):271-80.
25. Moser C, Tirakitsoontorn P, Nussbaum E, Newcomb R, Cooper DM. Muscle size and cardiorespiratory response to exercise in cystic fibrosis. Am J Respir Crit Care Med. 2000;162:1823-7.
26. Narang I, Pike S, Rosenthal M, Balfour-Lynn I, Bush A. Three-minute step test to assess exercise capacity in children with cystic fibrosis with mild lung disease. Pediatr Pulmonol. 2003;35:108-13.
27. Nixon PA, Orenstein DM. Exercise testing in children. Pediatr Pulmonol. 1988;5:107-22.
28. Nixon PA, Orenstein DM, Kelsey SF, Doershuk CF. The prognostic value of exercise testing in patients with cystic fibrosis. N Engl J Med. 1992;327(25):1785-8.
29. Orenstein D, Higgins L. Update on the role of exercise in cystic fibrosis. Curr Opin Pulm Med. 2005;11:519-23.
30. Orenstein DM, Hovell MF, Mulvihill M, et al. Strength vs aerobic training in children with cystic fibrosis. Chest. 2004;126:1204-14.
31. Pianosi P, LeBlanc J, Almudevar A. Peak oxygen uptake and mortality in children with cystic fibrosis. Thorax. 2005;60:50-4.
32. Reilly J, Edwards C, Weaver L. Malnutrition in children with cystic fibrosis: the energy-balance equation. J Pediatr Gastroenterol Nutr. 1997;25:127-36.
33. Richards ML, Davies PSW, Bell SC. Energy cost of physical activity in cystic fibrosis. Eur J Clin Nutr. 2001;55:690-7.
34. Schneiderman-Walkers J, Pollock SL, Corey M, et al. A randomized controlled trial of a 3-year home exercise program in cystic fibrosis. J Pediatr. 2000;136:304-10.
35. Selvadurai HC, Allen JC, Sachinwalla T, Macauley J, Blimkie CJ, Van Asperen PP. Muscle function and resting energy expenditure in female athletes with cystic fibrosis. Am J Respir Crit Care Med. 2003;168:1476-80.
36. Selvadurai HC, Blimkie CJ, Cooper PJ, Mellis CM, Van Asperen PP. Gender differences in habitual activity in children with cystic fibrosis. Arch Dis Child. 2004;89:928-33.
37. Sexauer WJ, Cheng H-K, Fiel SB. Utility of the breathing reserve index at the anaerobic threshold in determining ventilatory-limited exercise in adult cystic fibrosis patients. Chest. 2003;124(4):1469-75.
38. Shah AR, Gozal D, Keens TG. Determinants of aerobic and anaerobic exercise performance in cystic fibrosis. Am J Respir Crit Care Med. 1998;157:1145-50.
39. Shepherd RW, Greer RM, McNaughton SA, Wotton M, Cleghorn GJ. Energy expenditure and the body cell mass in cystic fibrosis. Nutrition. 2001;17:22-5.
40. Short KR, Sedlock DA. Excess postexercise oxygen consumption and recovery rate in trained and untrained subjects. J Appl Physiol. 1997;83(1):153-9.
41. Spicher V, Roulet M, Schutz Y. Assessment of total energy expenditure in free-living patients with cystic fibrosis. J Pediatr. 1991;118:865-72.
42. Stanghelle JK, Michalsen H, Skyberg D. Five-year follow-up of pulmonary function and peak oxygen uptake in 16-year-old boys with cystic fibrosis, with special regard to the influence of regular physical exercise. Int J Sports Med. 1988;9(suppl.):19-24.
43. Suri R, Metcalfe C, Wallis C, Bush A. Assessing the usefulness of outcomes measured in a cystic fibrosis treatment trial. Respir Med. 2007;101:254-60.
44. Tantisira KC, Systrom DM, Ginns LC. An elevated breathing reserve index at the lactate threshold is a predictor of mortality in patients with cystic fibrosis awaiting lung transplantation. Am J Respir Crit Care Med. 2002;165:1626-33.
45. Tirakitsoontorn P, Nussbaum E, Moser C, Hill M, Cooper D. Fitness, acute exercise and anabolic and catabolic mediators in cystic fibrosis. Am J Respir Crit Care Med. 2001;164:1432-7.
46. Tomezsko JL, Stallings VA, Kawchak DA, Goin JE, Diamond G, Scanlin TF. Energy expenditure and genotype of children with cystic fibrosis. Pediatr Res. 1994;35(4):451-60.
47. Vaisman N, Pencharz PB, Corey M, Canny GJ, Hahn E. Energy expenditure of patients with cystic fibrosis. J Pediatr. 1987;111:496-500.
48. Ward SA, Tomezsko JL, Holsclaw DS, Paolone AM. Energy expenditure and substrate utilization in adutls with cystic fibrosis and diabetes mellitus. Am J Clin Nutr. 1999;69:913-9.
49. Wasserman K, Hansen JE, Sue DY, Stringer WW, Whipp BJ. Principles of Exercise Testing and Interpretation; Including Pathophysiology & Clinical Applications. Philadelphia (PA): Lippincott Williams & Wilkins; 2005. p. 89-90; 172-4.
50. Weston A, Petrosa R, Pate R. Validation of an instrument for measurement of physical activity in youth. Med Sci Sports Exerc. 1997;29(1):138-43.