Health status and quality of life of elderly persons with severe hemophilia born before the advent of modern replacement therapy

Journal of Thrombosis and Haemostasis

Volumn 7, Issue 5, 2009, Pages 780-786

  Siboni, S M ^a   Mannucci, Pier M ^a,d   Gringeri, A ^a   Franchini, M ^b   Tagliaferri, A ^c   Ferretti, M ^a   Tradati, F C ^d   Santagostino, E ^a   Von Mackensen, S ^a,e   Baudo, F ^d   Tagariello, G ^d   Boeri, E ^d   Rodorigo, G ^d   Morfini, M ^d   Iorio, A ^d   Ferrante, F ^d   Landolfi, R ^f   Mazzucconi, M G ^g   Santoro, C ^g   Di Minno, G ^h   Coppola, A ^h   Rocino, A ⁱ   Ciavarella, N ^j   Scaraggi, A ^j   Latella, C ^d   Sottilotta, G ^k   Siragusa, S ^k   Targhetta, R ^d   Piseddu, G ^d   more..

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY HOSPITAL OF PARMA   (Italy)

^c Parma Hospital   (Italy)

^d IRCCS Maggiore Hospital ^*

^e UNIVERSITY OF HAMBURG   (Germany)

^f FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^g INSTM Research Unit Rome La Sapienza   (Italy)

^h FEDERICO II UNIVERSITY HOSPITAL   (Italy)

ⁱ Ospedale San Giovanni Bosco   (Italy)

^j POLICLINICO   (Italy)

^k Policlinico Palermo   (Italy)

more..

Author keywords

Aging; Cognitive status; Daily autonomy; Health related quality of life; Hemophilia; Physical functioning

Indexed keywords

BLOOD CLOTTING FACTOR CONCENTRATE;

AGE; AGED; ARTHROPATHY; ARTICLE; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; COGNITION; COMORBIDITY; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DEPRESSION; DISEASE SEVERITY; FEMALE; GENDER; GEOGRAPHIC DISTRIBUTION; HEALTH CARE DELIVERY; HEALTH STATUS; HEMOPHILIA; HEMOPHILIA A; HEMOPHILIA B; HEPATITIS B; HEPATITIS C; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERCHOLESTEROLEMIA; HYPERTENSION; ITALY; MALE; PRIORITY JOURNAL; QUALITY OF LIFE; SOCIAL STATUS; SUBSTITUTION THERAPY; VIRUS INFECTION;

EID: 65449139202     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2009.03318.x     Document Type: Article

References (32)

1. Mannucci PM. Back to the future: A recent history of haemophilia treatment. Haemophilia 2008; 14(Suppl. 3): 10-8.
2. Ikkala E, Helske T, Myllyla G, Nevanlinna HR, Pitkanen P, Rasi V. Changes in the life expectancy of patients with severe haemophilia A in Finland in 1930-79. Br J Haematol 1982; 52: 7-12.
3. Larsson SA, Wiechel B. Deaths in Swedish haemophiliacs, 1957-1980. Acta Med Scand 1983; 214: 199-206.
4. Smit C, Rosendaal FR, Varekamp I, Bröcker-Vriends A, van Dijck H, Suurmeijer TP, Briët E. Physical condition, longevity, and social performance of Dutch haemophiliacs, 1972-85. BMJ 1989; 298: 235-8.
5. Soucie JM, Nuss R, Evatt B, Abdelhak A, Cowan L, Hill H, Kolakoski M, Wilber N. Mortality among males with haemophilia: Relations with source of medical care. The Haemophilia Surveillance System Project Investigators. Blood 2000; 96: 437-42.
6. Street A, Hill K, Sussex B, Warner M, Scully MF. Haemophilia and ageing. Haemophilia 2006; 12(Suppl. 3): 8-12.
7. Darby SC, Kan SW, Spooner RJ, Giangrande PL, Hill FG, Hay CR, Lee CA, Ludlam CA, Williams M. Mortality rates, life expectancy, and causes of death in people with haemophilia A or B in the United Kingdom who were not infected with HIV. Blood 2007; 110: 815-25.
8. Franchini M, Tagliaferri A, Mannucci PM. The management of haemophilia in elderly patients. Clin Interv Aging 2007; 2: 361-8.
9. Johnson RE, Lawrence DN, Evatt BL, Bregman DJ, Zyla LD, Curran JW, Aledort LM, Eyster ME, Brownstein AP, Carman CJ. Acquired immunodeficiency syndrome among patients attending haemophlia treatment centers and mortality experience of haemophiliacs in the United States. Am J Epidemiol 1985; 121: 797-810.
10. Ragni MV, Tegtmeier GE, Levy JA, Kaminsky LS, Lewis JH, Spero JA, Bontempo FA, Handwerkleber C, Bayer WL, Zimmerman DH, Britz JA. AIDS retrovirus antibodies in haemophiliacs treated with factor VIII or factor IX concentrates, cryoprecipitate, or fresh-frozen plasma - prevalence, seroconversion rate, and clinical correlations. Blood 1986; 67: 592-5.
11. Chorba TL, Holman RC, Strine TW, Clarke MJ, Evatt BL. Changes in longevity and causes of death among persons with haemophilia A. Am J Hematol 1994; 45: 112-21.
12. Walker IR, Julian JA. Causes of death in Canadians with haemophilia 1980-1995. Haemophilia 1998; 4: 714-20.
13. Plug I, van der Bom JG, Peters M, Mauser-Bunschoten EP, De Goede-Bolder A, Heijnen L, Smit C, Willemse J, Rosendaal FR. Mortality and causes of death in patients with haemophilia, 1992-2001: A prospective cohort study. J Thromb Haemost 2006; 4: 510-6.
14. Linn BS, Linn MW, Gurel L. Cumulative illness rating scale. J Am Geriatr Soc 1968; 16: 622-6.
15. Salvi F, Miller MD, Grilli A, Giorni R, Towers AL, Morichi V, Spazzafumo L, Mancinelli L, Espinosa E, Rappelli A, Dessì-Fulgheri P. A manual of guidelines to score the modified cumulative illness rating scale and its validation in acute hospitalized elderly patients. J Am Gereatr Soc 2008; 56, 10: 1926-31.
16. Parmelee PA, Thuras PD, Katz IR, Lawton MP. Validation of the cumulative illness rating scale in a geriatric residential population. J Am Geriatr Soc 1995; 43: 130-7.
17. Gilbert MS. Prophylaxis. Muscoloskeletal evaluation. Semin Hematol 1993; 30: 3-6.
18. Kempen GI, Myers AM, Powell LE. Hierarchical structure in ADL and IADL: analytical assumptions and applications for clinicians and researchers. J Clin Epidemiol 1995; 48: 1299-305.
19. Vergani C, Lucchi T. Note pratiche di diagnosi e terapia per l'anziano. Seconda edizione. Milano: Elsevier, 2008.
20. Lawton MP, Brody EM. Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist 1969; 9: 179-86.
21. http://www.interrai.org/section/view/; accessed 25 February 2009.
22. Tinetti ME. Performance-oriented assessment of mobility problems in elderly patients. J Am Geriatr Soc 1986; 34: 119-26.
23. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-98.
24. Bravo G, Hébert R. Age- and education-specific reference values for the mini-mental and modified mini-mental state examinations derived from a non-demented elderly population. Int J Geriatr Psychiatry 1997; 12: 1008-18.
25. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: A preliminary report. J Psychiatr Res 1982-1983; 17: 37-49.
26. EuroQol Group. http://www.euroqol.org; accessed 25 February 2009.
27. Neri M, Cortelloni C, Andermacher E, SpanóA, De Vreese L, Motta M, Giorgi G, Vecchi GP. La valutazione dello stato mentale. In: Vecchi GP, ed. Il Centro di Valutazione Geriatrica. Florence: Editrice Mattioli, 1990: 21-7.
28. Maugeri D, Testa M, Santangelo A, Abbate S, Bennati E, Bonanno MR, Lo Giudice F, Mamazza C, Panebianco P. Cardiovascular aging and psychometric performances: Correlations in a group of ultraseptagenarian elderly. Arch Gerontol Geriatr 2005; 40: 1-5.
29. Iorio A, Oliovecchio E, Morfini M, Mannucci PM. Association of Italian haemophilia centres directors. Italian registry of haemophilia and allied disorders. Objectives, methodology and data analysis. Haemophilia 2008; 14: 444-53.
30. Hartl HK, Reitter S, Eidher U, Ramschak H, Ay C, Pabinger I. The impact of severe haemophilia on the social status and quality of life among Austrian haemophiliacs. Haemophilia 2008; 1: 1-6.
31. Kulkarni R, Soucie JM, Evatt BL. Haemophlia Surveillance System Project Investigators. Prevalence and risk factors for heart disease among males with haemophilia. Am J Hematol 2005; 79: 36-42.
32. Srámek A, Reiber JH, Gerrits WB, Rosendaal FR. Decreased coagulability has no clinically relevant effect on atherogenesis: observations in individuals with a hereditary bleeding tendency. Circulation 2001; 104: 762-7.