Cyst formation in kidney via B-raf signaling in the PKD2 transgenic mice

Journal of Biological Chemistry

Volumn 284, Issue 11, 2009, Pages 7214-7222

  Park, Eun Young ^a   Sung, Young Hoon ^b   Yang, Moon Hee ^a   Noh, Ji Yeun ^a   Park, So Young ^a   Lee, Tae Young ^a   Yook, Yeon Joo ^a   Yoo, Kyung Hyun ^a   Roh, Kyung Jin ^c   Kim, Ingyu ^d   Hwang, Young Hwan ^e   Oh, Goo Taeg ^f   Seong, Je Kyung ^c   Ahn, Curie ^g   Lee, Han Woong ^b   Park, Jong Hoon ^a  

^a Sookmyung Women's University   (South Korea)

^b Yonsei University   (South Korea)

^c Seoul National University   (South Korea)

^d VANDERBILT UNIVERSITY   (United States)

^e Eulji University School of Medicine   (South Korea)

^f Ewha Womans University   (South Korea)

^g Seoul National University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CHEMICAL ACTIVATION; MOLECULAR INTERACTIONS;

AUTOSOMAL DOMINANTS; FUNCTIONAL PRODUCTS; MOLECULAR MECHANISM; OVER-EXPRESSION; PATHOGENIC MECHANISMS; POLYCYSTIC KIDNEY DISEASE; PROLIFERATION AND APOPTOSIS; TRANSGENIC MICE;

MAMMALS;

B RAF KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; POLYCYSTIN 2; BRAF PROTEIN, HUMAN; BRAF PROTEIN, MOUSE; POLYCYSTIC KIDNEY DISEASE 2 PROTEIN; POLYCYSTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE OVEREXPRESSION; KIDNEY CYST; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UPREGULATION; ANIMAL; BIOSYNTHESIS; CYST; DISEASE MODEL; FEMALE; GENETICS; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; KIDNEY; KIDNEY POLYCYSTIC DISEASE; MALE; METABOLISM; MUTATION; PATHOLOGY; PHENOTYPE;

MUS; MUS MUSCULUS;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CYSTS; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; KIDNEY; MALE; MICE; MICE, INBRED ICR; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUTATION; PHENOTYPE; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT; PROTO-ONCOGENE PROTEINS B-RAF; SIGNAL TRANSDUCTION; TRPP CATION CHANNELS;

EID: 65449139184     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805890200     Document Type: Article

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