The identification of bioisosteres as drug development candidates

Innovations in Pharmaceutical Technology

Volumn , Issue 28, 2009, Pages 22-26

  Cheeseright, Tim ^a  

^a Cresset BioMolecular Discovery Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; BENZAMIDINE; BLOOD CLOTTING FACTOR 10A; CELECOXIB; ETORICOXIB; NEW DRUG; PARECOXIB; ROFECOXIB; THROMBIN; TRIAZOLE DERIVATIVE; VALDECOXIB;

ARTICLE; DRUG ACTIVITY; DRUG INDUSTRY; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; HIGH THROUGHPUT SCREENING; PATENT; PHARMACOPHORE; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 65449128473     PISSN: 14717204     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Article

References (3)

1. Vinter A and Rose S, Molecular Field Technology and its Applications in Drug Discovery, Innovations in Pharmaceutical Technology, 23, pp14-18, 2007
2. Bellenie OR, Barton NP, Emmons AJ, et al, Discovery and optimization of highly ligand-efficient oxytocin receptor antagonists using structure-based drug, Bioorganic and Medicinal Chemistry Letters, 19, pp990-994, 2009
3. Dart MJ, Wasicak JT, Ryther KS, et al, Structural aspects of high affinity ligands for the a4b2 neuronal nicotinic receptor, Pharmaceutica Acta Hevetiae, 74, pp115, 2000