Regulation of GCL activity and cellular glutathione through inhibition of ERK phosphorylation

BioFactors

Volumn 33, Issue 1, 2008, Pages 1-11

  Chen, Zhi Hua ^a   Saito, Yoshiro ^a   Yoshida, Yasukazu ^a   Noguchi, Noriko ^b,c   Niki, Etsuo ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c DOSHISHA UNIVERSITY   (Japan)

Author keywords

B Raf MEK ERK; GCL; GSH; Oxidative stress; Phosphorylation dephosphorylation

Indexed keywords

B RAF KINASE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; NERVE GROWTH FACTOR; NITRILE; SMALL INTERFERING RNA;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE CONTROL; GENE INDUCTION; NONHUMAN; PRIORITY JOURNAL; RAT; UPREGULATION; ANIMAL; CELL STRAIN; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; OXIDATIVE STRESS; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; BUTADIENES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; NERVE GROWTH FACTOR; NITRILES; OXIDATIVE STRESS; PC12 CELLS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS B-RAF; RATS; RNA, SMALL INTERFERING;

EID: 65449127011     PISSN: 09516433     EISSN: None     Source Type: Journal    
DOI: 10.1002/biof.5520330101     Document Type: Article

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