HIV diversity in venezuela: Predominance of HIV type 1 subtype B and genomic characterization of non-B variants

AIDS Research and Human Retroviruses

Volumn 25, Issue 3, 2009, Pages 347-350

  Rangel, Héctor R ^a   Garzaro, Domingo ^a   Gutiérrez, Cristina R ^b   Vásquez, Luzmary ^c   Guillen, Genni ^d   Torres, Jaime R ^e   Pujol, Flor H ^a  

^a Instituto Venezolano de Investigaciones Cientificas Centro de Microbiologia y Biologia Celular   (Venezuela)

^b Instituto Nacional de Higiene Rafael Rangel   (Venezuela)

^c Hospital Central de Barquisimeto   (Venezuela)

^d UNIVERSIDAD DE ORIENTE   (Venezuela)

^e UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

NEF PROTEIN; POL PROTEIN; VIF PROTEIN; VIRUS ENVELOPE PROTEIN;

ARTICLE; GENETIC VARIABILITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS; UNINDEXED SEQUENCE; VIRUS CHARACTERIZATION; VIRUS GENOME; VIRUS ISOLATION; VIRUS STRAIN; CLASSIFICATION; CLUSTER ANALYSIS; DNA SEQUENCE; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; ISOLATION AND PURIFICATION; SEQUENCE HOMOLOGY; VENEZUELA; VIROLOGY;

CLUSTER ANALYSIS; GENOTYPE; HIV INFECTIONS; HIV-1; HUMANS; PHYLOGENY; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; VENEZUELA;

EID: 65449116537     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2008.0241     Document Type: Article

References (15)

1. Buonaguro L, Tornesello ML, and Buonaguro FM: Human immunodeficiency virus type 1 subtype distribution in the worldwide epidemic: Pathogenetic and therapeutic implications. J Virol 2007;81:10209-10219.
2. Gilbert MT, Rambaut A, Wlasiuk G, Spira TJ, Pitchenik AE, and Worobey M: The emergence of HIV/AIDS in the Americas and beyond. Proc Natl Acad Sci USA 2007;104:18566-18570.
3. Avila MM, Pando MA, Carrion G, Peralta LM, Salomon H, Carrillo MG, Sanchez J, Maulen S, Hierholzer J, Marinello M, Negrete M, Russell KL, and Carr JK: Two HIV-1 epidemics in Argentina: Different genetic subtypes associated with different risk groups. J Acquir Immune Defic Syndr 2002;29:422-426.
4. Castro E, Moreno M, Deibis, L, de Pérez G, Salmen S, and Berrueta L: Trends of HIV-1 molecular epidemiology in Venezuela: Introduction of subtype C and identification of a novel B/C mosaic genome. J Clin Virol 2005;32:257-258.
5. Rangel HR, Garzaro DJ, Torres JR, Castro J, Suarez A, Naranjo L, Martinez N, the Resistance Committee Group, Gutierrez C, and Pujol FH: Antiretroviral drug resistance prevalence in Venezuela. Mem Inst Osw Cruz (in press).
6. Rangel HR, Garzaro DJ, Rodríguez AK, Ramírez AH, Ameli G, Gutiérrez CR, and Pujol FH: Deletion, insertion and stop codon mutations in Vif genes of HIV-1 infecting slow progressor patients. Submitted.
7. Ball SC, Abraha A, Collins KR, Marozsan AJ, Baird H, Quiñones-Mateu ME, Penn-Nicholson A, Murray M, Richard N, Lobritz M, Zimmerman PA, Kawamura T, Blauvelt A, and Arts EJ: Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C. J Virol 2003;77:1021-1038.
8. Gomez-Carrillo M, Pampuro S, Duran A, Losso M, Harris DR, Read JS, Duarte G, De Souza R, Soto-Ramirez L, and Salomon H: NISDI Perinatal Study Group: Analysis of HIV type 1 diversity in pregnant women from four Latin American and Caribbean countries. AIDS Res Hum Retro-viruses 2006;22:1186-1191.
9. Peeters M, Esu-Williams E, Vergne L, Montavon C, Mulanga-Kabeya C, Harry T, Ibironke A, Lesage D, Patrel D, and Delaporte E: Predominance of subtype A and G HIV type 1 in Nigeria, with geographical differences in their distribution. AIDS Res Hum Retroviruses 2000;16:315-325.
10. Abecasis AB, Lemey P, Vidal N, de Oliveira T, Peeters M, Camacho R, Shapiro B, Rambaut A, and Vandamme AM: Recombination confounds the early evolutionary history of human immunodeficiency virus type 1: Subtype G is a circulating recombinant form. J Virol 2007;81:8543-8551.
11. Ojesina AI and Kanki PJ: Transcriptase genotype: Role for geographical location and founder effects. PLoS Med 2006; 3:e540.
12. Pérez L, Thomson MM, Bleda MJ, Aragonés C, González Z, Pérez J, Sierra M, Casado G, Delgado E, and Nájera R: HIV type 1 molecular epidemiology in Cuba: High genetic diversity, frequent mosaicism, and recent expansion of BG intersubtype recombinant forms. AIDS Res Hum Retroviruses 2006;22:724-733.
13. Torres JR, Torres-Viera MA, Schupbach J, Rangel HR, and Pujol FH: Non-immune thrombocytopenia responsive to antiretroviral therapy and HIV-2 infection. J Infect 2007;54: e21-24.
14. Cilla G, Rodés B, Pérez-Trallero E, Arrizabalaga J, and Soriano V: Molecular evidence of homosexual transmission of HIV type 2 in Spain. AIDS Res Hum Retroviruses 2001;17: 417-422.
15. Fusuma EE, Caruso SC, Lopez DF, Costa LJ, Janini LM, De Mendonça JS, Kallas EG, and Diaz RS: Duplication of perikappaB and NF-kappab sites of the first human immunodeficiency virus type 2 (HIV-2) transmission in Brazil. AIDS Res Hum Retroviruses 2005;21:965-970.