Cyclosporin A, but not everolimus, inhibits DNA repair in human fibroblasts and lymphoblasts

International Journal of Clinical Pharmacology and Therapeutics

Volumn 47, Issue 1, 2009, Pages 38-40

  Kuschal, C ^a   Thoms, K M ^a   Mori, T ^b   Kobayashi, N ^b   Bockmann L ^a   Laspe, P ^a   Emmert, S ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

DNA repair; Immunosuppressants; Transplantation; UV irradiation; Xeroderma pigmentosum

Indexed keywords

CYCLOSPORIN A; DNA; EVEROLIMUS; LUCIFERASE; CYCLOSPORIN; DRUG DERIVATIVE; FIREFLY LUCIFERASE; IMMUNOSUPPRESSIVE AGENT; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE; PYRIMIDINE DIMER; RAPAMYCIN;

CELL LINE; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; DNA ISOLATION; DNA REPAIR; DRUG ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; GENETIC TRANSFECTION; HOST CELL; HUMAN; HUMAN CELL; LYMPHOBLAST; PLASMID; PROTEIN EXPRESSION; ULTRAVIOLET RADIATION; ARTICLE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; GENETICS; IMMUNOLOGY; METABOLISM; PRE B LYMPHOCYTE; RADIATION EXPOSURE; RADIATION RESPONSE; TIME;

CELL LINE; CELL SURVIVAL; CYCLOSPORINE; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LUCIFERASES, FIREFLY; PRECURSOR CELLS, B-LYMPHOID; PROTEIN KINASES; PYRIMIDINE DIMERS; SIROLIMUS; TIME FACTORS; ULTRAVIOLET RAYS;

EID: 65349183959     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: 10.5414/CPP47038     Document Type: Conference Paper

References (6)

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