-
2
-
-
0025104027
-
TGF-beta stimulation and inhibition of cell proliferation: New mechanistic insights
-
Moses HL, Yang EY, Pietenpol JA 1990 TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights. Cell 63:245-247
-
(1990)
Cell
, vol.63
, pp. 245-247
-
-
Moses, H.L.1
Yang, E.Y.2
Pietenpol, J.A.3
-
3
-
-
0029952544
-
Arrested lung morphogenesis in transgenic mice bearing a SP-C-TGF-beta 1 chimeric gene
-
Zhou L, Dey CR, Wert SE, Whitsett JA 1996 Arrested lung morphogenesis in transgenic mice bearing a SP-C-TGF-beta 1 chimeric gene. Dev Biol 175:227-238
-
(1996)
Dev Biol
, vol.175
, pp. 227-238
-
-
Zhou, L.1
Dey, C.R.2
Wert, S.E.3
Whitsett, J.A.4
-
4
-
-
0034743486
-
TGF-beta1 perturbs vascular development and inhibits epithelial differentiation in fetal lung in vivo
-
Zeng X, Gray M, Stahlman MT, Whitsett JA 2001 TGF-beta1 perturbs vascular development and inhibits epithelial differentiation in fetal lung in vivo. Dev Dyn 221:289-301
-
(2001)
Dev Dyn
, vol.221
, pp. 289-301
-
-
Zeng, X.1
Gray, M.2
Stahlman, M.T.3
Whitsett, J.A.4
-
5
-
-
0028168129
-
TGF beta 1 inhibits branching morphogenesis and n-myc expression in lung bud organ cultures
-
Serra R, Pelton RW, Moses HL 1994 TGF beta 1 inhibits branching morphogenesis and n-myc expression in lung bud organ cultures. Development 120:2153-2161
-
(1994)
Development
, vol.120
, pp. 2153-2161
-
-
Serra, R.1
Pelton, R.W.2
Moses, H.L.3
-
6
-
-
0034755294
-
Signaling to the epithelium is not sufficient to mediate all of the effects of transforming growth factor beta and bone morphogenetic protein 4 on murine embryonic lung development
-
Bragg AD, Moses HL, Serra R 2001 Signaling to the epithelium is not sufficient to mediate all of the effects of transforming growth factor beta and bone morphogenetic protein 4 on murine embryonic lung development. Mech Dev 109:13-26
-
(2001)
Mech Dev
, vol.109
, pp. 13-26
-
-
Bragg, A.D.1
Moses, H.L.2
Serra, R.3
-
7
-
-
0030602054
-
Abrogation of transforming growth factor-beta type II receptor stimulates embryonic mouse lung branching morphogenesis in culture
-
Zhao J, Bu D, Lee M, Slavkin HC, Hall FL, Warburton D 1996 Abrogation of transforming growth factor-beta type II receptor stimulates embryonic mouse lung branching morphogenesis in culture. Dev Biol 180:242-257
-
(1996)
Dev Biol
, vol.180
, pp. 242-257
-
-
Zhao, J.1
Bu, D.2
Lee, M.3
Slavkin, H.C.4
Hall, F.L.5
Warburton, D.6
-
8
-
-
0025122809
-
TGF-beta receptors and TGF-beta binding proteoglycans: Recent progress in identifying their functional properties
-
Massague J, Cheifetz S, Boyd FT, Andres LJ 1990 TGF-beta receptors and TGF-beta binding proteoglycans: recent progress in identifying their functional properties. Ann NY Acad Sci 593:59-72
-
(1990)
Ann NY Acad Sci
, vol.593
, pp. 59-72
-
-
Massague, J.1
Cheifetz, S.2
Boyd, F.T.3
Andres, L.J.4
-
9
-
-
0027332995
-
Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor
-
Franzen P, ten Dijke P, Ichijo H, Yamashita H, Schulz P, Heldin CH, Miyazono K 1993 Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor. Cell 75:681-692
-
(1993)
Cell
, vol.75
, pp. 681-692
-
-
Franzen, P.1
ten Dijke, P.2
Ichijo, H.3
Yamashita, H.4
Schulz, P.5
Heldin, C.H.6
Miyazono, K.7
-
10
-
-
0031685620
-
TGF-beta signal transduction
-
Massague J 1998 TGF-beta signal transduction. Annu Rev Biochem 67:753-791
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
11
-
-
0034654497
-
Controlling TGF-beta signaling
-
Massague J, Chen YG 2000 Controlling TGF-beta signaling. Genes Dev 14:627-644
-
(2000)
Genes Dev
, vol.14
, pp. 627-644
-
-
Massague, J.1
Chen, Y.G.2
-
12
-
-
0032547272
-
Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members
-
Afrakhte M, Moren A, Jossan S, Itoh S, Sampath K, Westermark B, Heldin CH, Heldin NE, ten Dijke P 1998 Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members. Biochem Biophys Res Commun 249:505-511
-
(1998)
Biochem Biophys Res Commun
, vol.249
, pp. 505-511
-
-
Afrakhte, M.1
Moren, A.2
Jossan, S.3
Itoh, S.4
Sampath, K.5
Westermark, B.6
Heldin, C.H.7
Heldin, N.E.8
ten Dijke, P.9
-
13
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF- signaling
-
Derynck R, Zhang YE 2003 Smad-dependent and Smad-independent pathways in TGF- signaling. Nature 425:577-584
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
15
-
-
0035957924
-
Transcriptional cross-talk between Smad, erk1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic atdc5 cells
-
Watanabe H, de Caestecker MP, Yamada Y 2001 Transcriptional cross-talk between Smad, erk1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic atdc5 cells. J Biol Chem 276:14466-14473
-
(2001)
J Biol Chem
, vol.276
, pp. 14466-14473
-
-
Watanabe, H.1
de Caestecker, M.P.2
Yamada, Y.3
-
16
-
-
2342423382
-
Differential activation of MAPK signaling pathways by TGF-beta1 forms the molecular mechanism behind its dose-dependent bidirectional effects on hematopoiesis
-
Kale VP 2004 Differential activation of MAPK signaling pathways by TGF-beta1 forms the molecular mechanism behind its dose-dependent bidirectional effects on hematopoiesis. Stem Cells Dev 13:27-38
-
(2004)
Stem Cells Dev
, vol.13
, pp. 27-38
-
-
Kale, V.P.1
-
17
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ 2000 Signal transduction by the JNK group of MAP kinases. Cell 103:239-252
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
18
-
-
0024276523
-
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1
-
Angel P, Hattori K, Smeal T, Karin M 1988 The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. Cell 55:875-885
-
(1988)
Cell
, vol.55
, pp. 875-885
-
-
Angel, P.1
Hattori, K.2
Smeal, T.3
Karin, M.4
-
19
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ 1994 JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.H.3
Barrett, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.J.8
-
20
-
-
0032572723
-
Smad3 and Smad4 cooperate with c-jun/c-fos to mediateTGF-beta-induced transcription
-
Zhang Y, Feng XH, Derynck R 1998 Smad3 and Smad4 cooperate with c-jun/c-fos to mediateTGF-beta-induced transcription. Nature 394:909-913
-
(1998)
Nature
, vol.394
, pp. 909-913
-
-
Zhang, Y.1
Feng, X.H.2
Derynck, R.3
-
21
-
-
0033601179
-
Interdependent Smad and JNK signaling in transforming growth factor-beta-mediated transcription
-
Engel ME, McDonnell MA, Law BK, Moses HL 1999 Interdependent Smad and JNK signaling in transforming growth factor-beta-mediated transcription. J Biol Chem 274:37413-37420
-
(1999)
J Biol Chem
, vol.274
, pp. 37413-37420
-
-
Engel, M.E.1
McDonnell, M.A.2
Law, B.K.3
Moses, H.L.4
-
22
-
-
34247642643
-
Alk-5 mediates endogenous and tgf-beta1-induced expression of connective tissue growth factor in embryonic lung
-
Wu S, Peng J, Duncan MR, Kasisomayajula K, Grotendorst G, Bancalari E 2007 Alk-5 mediates endogenous and tgf-beta1-induced expression of connective tissue growth factor in embryonic lung. Am J Respir Cell Mol Biol 36:552-561
-
(2007)
Am J Respir Cell Mol Biol
, vol.36
, pp. 552-561
-
-
Wu, S.1
Peng, J.2
Duncan, M.R.3
Kasisomayajula, K.4
Grotendorst, G.5
Bancalari, E.6
-
23
-
-
0032519946
-
Abrogation of Smad3 and Smad2 or of Smad4 gene expression positively regulates murine embryonic lung branching morphogenesis in culture
-
Zhao J, Lee M, Smith S, Warburton D 1998 Abrogation of Smad3 and Smad2 or of Smad4 gene expression positively regulates murine embryonic lung branching morphogenesis in culture. Dev Biol 194:182-195
-
(1998)
Dev Biol
, vol.194
, pp. 182-195
-
-
Zhao, J.1
Lee, M.2
Smith, S.3
Warburton, D.4
-
24
-
-
0027219381
-
The modular architecture of a new family of growth regulators related to connective tissue growth factor
-
Bork P 1993 The modular architecture of a new family of growth regulators related to connective tissue growth factor. FEBS Lett 327:125-130
-
(1993)
FEBS Lett
, vol.327
, pp. 125-130
-
-
Bork, P.1
-
25
-
-
0442291674
-
The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology
-
Leask A, Abraham DJ 2003 The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology. Biochem Cell Biol 81:355-363
-
(2003)
Biochem Cell Biol
, vol.81
, pp. 355-363
-
-
Leask, A.1
Abraham, D.J.2
-
26
-
-
0031225015
-
Connective tissue growth factor: A mediator of TGF-beta action on fibroblasts
-
Grotendorst GR 1997 Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev 8:171-179
-
(1997)
Cytokine Growth Factor Rev
, vol.8
, pp. 171-179
-
-
Grotendorst, G.R.1
-
27
-
-
0031659897
-
Inhibition of TGF-beta-stimulated CTGF gene expression and anchorage-independent growth by cAMP identifies a CTGF-dependent restriction point in the cell cycle
-
Kothapalli D, Hayashi N, Grotendorst GR 1998 Inhibition of TGF-beta-stimulated CTGF gene expression and anchorage-independent growth by cAMP identifies a CTGF-dependent restriction point in the cell cycle. FASEB J 12:1151-1161
-
(1998)
FASEB J
, vol.12
, pp. 1151-1161
-
-
Kothapalli, D.1
Hayashi, N.2
Grotendorst, G.R.3
-
28
-
-
0032873465
-
Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: Down-regulation by cAMP
-
Duncan MR, Frazier KS, Abramson S, Williams S, Klapper H, Huang X, Grotendorst GR 1999 Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: down-regulation by cAMP. FASEB J 13:1774-1786
-
(1999)
FASEB J
, vol.13
, pp. 1774-1786
-
-
Duncan, M.R.1
Frazier, K.S.2
Abramson, S.3
Williams, S.4
Klapper, H.5
Huang, X.6
Grotendorst, G.R.7
-
29
-
-
1542343906
-
Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation
-
Grotendorst GR, Rahmanie H, Duncan MR 2004 Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation. FASEB J 18:469-479
-
(2004)
FASEB J
, vol.18
, pp. 469-479
-
-
Grotendorst, G.R.1
Rahmanie, H.2
Duncan, M.R.3
-
30
-
-
0035923665
-
SP600125, an anthrapyrazolone inhibitor of jun n-terminal kinase
-
Bennett BL, Sasaki DT, Murray BW, O'Leary EC, Sakata ST, Xu W, Leisten JC, Motiwala A, Pierce S, Satoh Y 2001 SP600125, an anthrapyrazolone inhibitor of jun n-terminal kinase. Proc Natl Acad Sci USA 98:13681-13686
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13681-13686
-
-
Bennett, B.L.1
Sasaki, D.T.2
Murray, B.W.3
O'Leary, E.C.4
Sakata, S.T.5
Xu, W.6
Leisten, J.C.7
Motiwala, A.8
Pierce, S.9
Satoh, Y.10
-
31
-
-
0035152487
-
Cell-permeable peptide inhibitors of JNK: Novel blockers of beta-cell death
-
Bonny C, Oberson A, Negri S, Sauser C, Schorderet DF 2001 Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death. Diabetes 50:77-82
-
(2001)
Diabetes
, vol.50
, pp. 77-82
-
-
Bonny, C.1
Oberson, A.2
Negri, S.3
Sauser, C.4
Schorderet, D.F.5
-
32
-
-
31444431904
-
Induction of endonuclease G-medictaed apoptosis in human oral sequamous cell carcinoma cells by protein kinase C inhibitor satingol
-
Hamada M, Sumi T, Iwai S, Nakazawa M, Yura Y 2006 Induction of endonuclease G-medictaed apoptosis in human oral sequamous cell carcinoma cells by protein kinase C inhibitor satingol. Apoptosis 11:47-56
-
(2006)
Apoptosis
, vol.11
, pp. 47-56
-
-
Hamada, M.1
Sumi, T.2
Iwai, S.3
Nakazawa, M.4
Yura, Y.5
-
33
-
-
34547116475
-
Jun kinase delay caspase-9 activation by interaction with apoptosome
-
Tran TH, Andreka P, Rodrigues CO, Webster KA, Bishopric NH 2007 Jun kinase delay caspase-9 activation by interaction with apoptosome. J Biol Chem 282:20340-20350
-
(2007)
J Biol Chem
, vol.282
, pp. 20340-20350
-
-
Tran, T.H.1
Andreka, P.2
Rodrigues, C.O.3
Webster, K.A.4
Bishopric, N.H.5
-
34
-
-
0035932976
-
C-jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity
-
Pessah M, Prunier C, Marais J, Ferrand N, Mazars A, Lallemand F, Gauthier JM, Atfi A 2001 C-jun interacts with the corepressor TG-interacting factor (TGIF) to suppress Smad2 transcriptional activity. Proc Natl Acad Sci USA 98:6198-6203
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6198-6203
-
-
Pessah, M.1
Prunier, C.2
Marais, J.3
Ferrand, N.4
Mazars, A.5
Lallemand, F.6
Gauthier, J.M.7
Atfi, A.8
-
35
-
-
0037047317
-
C-jun associates with the oncoprotein ski and suppresses Smad2 transcriptional activity
-
Pessah M, Marais J, Prunier C, Ferrand N, Lallemand F, Mauviel A, Atfi A 2002 C-jun associates with the oncoprotein ski and suppresses Smad2 transcriptional activity. J Biol Chem 277:29094-29100
-
(2002)
J Biol Chem
, vol.277
, pp. 29094-29100
-
-
Pessah, M.1
Marais, J.2
Prunier, C.3
Ferrand, N.4
Lallemand, F.5
Mauviel, A.6
Atfi, A.7
-
36
-
-
0041854299
-
5-fluorouracil blocks transforming growth factor-beta-induced alpha 2 type I collagen gene (COL1A2) expression in human fibroblasts via c-Jun NH2-terminal kinase/activator protein-1 activation
-
Wendling J, Marchand A, Mauviel A, Verrecchia F 2003 5-fluorouracil blocks transforming growth factor-beta-induced alpha 2 type I collagen gene (COL1A2) expression in human fibroblasts via c-Jun NH2-terminal kinase/activator protein-1 activation. Mol Pharmacol 64:707-713
-
(2003)
Mol Pharmacol
, vol.64
, pp. 707-713
-
-
Wendling, J.1
Marchand, A.2
Mauviel, A.3
Verrecchia, F.4
-
38
-
-
0035815683
-
CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling
-
Holmes A, Abraham DJ, Sa S, Shiwen X, Black CM, Leask A 2001 CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling. J Biol Chem 276:10594-10601
-
(2001)
J Biol Chem
, vol.276
, pp. 10594-10601
-
-
Holmes, A.1
Abraham, D.J.2
Sa, S.3
Shiwen, X.4
Black, C.M.5
Leask, A.6
-
39
-
-
0038644847
-
Connective tissue growth factor gene expression: Requirments for its induction by transforming growth factor-β2 in fibroblasts
-
Leask A, Holmes A, Black CM, Abraham DJ 2003 Connective tissue growth factor gene expression: requirments for its induction by transforming growth factor-β2 in fibroblasts. J Biol Chem 278:13008-13015
-
(2003)
J Biol Chem
, vol.278
, pp. 13008-13015
-
-
Leask, A.1
Holmes, A.2
Black, C.M.3
Abraham, D.J.4
-
40
-
-
0037636775
-
C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts
-
Utsugi M, Dobashi K, Ishizuka T, Masubuchic K, Shimizu Y, Nakazawa T, Mori M 2003 C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts. Am J Respir Cell Mol Biol 28:754-761
-
(2003)
Am J Respir Cell Mol Biol
, vol.28
, pp. 754-761
-
-
Utsugi, M.1
Dobashi, K.2
Ishizuka, T.3
Masubuchic, K.4
Shimizu, Y.5
Nakazawa, T.6
Mori, M.7
|