-
1
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: Therapeutic implications. N Engl J Med. 1971; 285: 1182-6.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
2
-
-
0031039243
-
The biology of vascular endothelial growth factor
-
Ferrara N, Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev. 1997; 18: 4-25.
-
(1997)
Endocr Rev
, vol.18
, pp. 4-25
-
-
Ferrara, N.1
Davis-Smyth, T.2
-
3
-
-
0029021904
-
Endothelial receptor tyrosine kinases involved in angiogenesis
-
Mustonen T, Alitalo K. Endothelial receptor tyrosine kinases involved in angiogenesis. J Cell Biol. 1995; 129: 895-8.
-
(1995)
J Cell Biol
, vol.129
, pp. 895-898
-
-
Mustonen, T.1
Alitalo, K.2
-
4
-
-
0030952289
-
Mechanisms of angiogenesis
-
Risau W. Mechanisms of angiogenesis. Nature. 1997; 386: 671-4.
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
5
-
-
0035003384
-
Structure and function of VEGF/VEGF-receptor system involved in angiogenesis
-
Shibuya M. Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Struct Funct. 2001; 26: 25-35.
-
(2001)
Cell Struct Funct
, vol.26
, pp. 25-35
-
-
Shibuya, M.1
-
6
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004; 350: 2335-42.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
7
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med. 2006; 355: 2542-50.
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
8
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Eisen T, Stadler WM et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med. 2007; 356: 125-34.
-
(2007)
N Engl J Med
, vol.356
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
-
9
-
-
0035692285
-
Possible mechanisms of acquired resistance to anti-angiogenic drugs: Implications for the use of combination therapy approaches
-
Kerbel RS, Yu J, Tran J et al. Possible mechanisms of acquired resistance to anti-angiogenic drugs: Implications for the use of combination therapy approaches. Cancer Metastasis Rev. 2001; 20: 79-86.
-
(2001)
Cancer Metastasis Rev
, vol.20
, pp. 79-86
-
-
Kerbel, R.S.1
Yu, J.2
Tran, J.3
-
11
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
Harris AL. Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer. 2002; 2: 38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
12
-
-
0029117223
-
Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
-
Ikeda E, Achen MG, Breier G, Risau W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem. 1995; 270: 19761-6.
-
(1995)
J Biol Chem
, vol.270
, pp. 19761-19766
-
-
Ikeda, E.1
Achen, M.G.2
Breier, G.3
Risau, W.4
-
13
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouyssegur J, Dayan F, Mazure NM. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature. 2006; 441: 437-43.
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
14
-
-
23844450576
-
A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxia-inducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma
-
Das B, Yeger H, Tsuchida R et al. A hypoxia-driven vascular endothelial growth factor/Flt1 autocrine loop interacts with hypoxia-inducible factor-1alpha through mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 pathway in neuroblastoma. Cancer Res. 2005; 65: 7267-75.
-
(2005)
Cancer Res
, vol.65
, pp. 7267-7275
-
-
Das, B.1
Yeger, H.2
Tsuchida, R.3
-
15
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science. 1956; 123: 309-14.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
16
-
-
0033386524
-
Resistance to apoptosis induced by microenvironmental stresses is correlated with metastatic potential in Lewis lung carcinoma
-
Takasu M, Tada Y, Wang JO, Tagawa M, Takenaga K. Resistance to apoptosis induced by microenvironmental stresses is correlated with metastatic potential in Lewis lung carcinoma. Clin Exp Metastasis. 1999; 17: 409-16.
-
(1999)
Clin Exp Metastasis
, vol.17
, pp. 409-416
-
-
Takasu, M.1
Tada, Y.2
Wang, J.O.3
Tagawa, M.4
Takenaga, K.5
-
17
-
-
34250870604
-
Prolonged hypoxia concomitant with serum deprivation induces massive human mesenchymal stem cell death
-
Potier E, Ferreira E, Meunier A, Sedel L, Logeart-Avramoglou D, Petite H. Prolonged hypoxia concomitant with serum deprivation induces massive human mesenchymal stem cell death. Tissue Eng. 2007; 13: 1325-31.
-
(2007)
Tissue Eng
, vol.13
, pp. 1325-1331
-
-
Potier, E.1
Ferreira, E.2
Meunier, A.3
Sedel, L.4
Logeart-Avramoglou, D.5
Petite, H.6
-
18
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan P, Storeng R, Scudiero D et al. New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst. 1990; 82: 1107-12.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
-
19
-
-
34547768293
-
Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle
-
Yamauchi M, Imajoh-Ohmi S, Shibuya M. Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle. Cancer Sci. 2007; 98: 1491-7.
-
(2007)
Cancer Sci
, vol.98
, pp. 1491-1497
-
-
Yamauchi, M.1
Imajoh-Ohmi, S.2
Shibuya, M.3
-
20
-
-
10344231494
-
Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina
-
Gotoh N, Ito M, Yamamoto S et al. Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina. Proc Natl Acad Sci USA. 2004; 101: 17144-9.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17144-17149
-
-
Gotoh, N.1
Ito, M.2
Yamamoto, S.3
-
21
-
-
0034046944
-
Plat-E, an efficient and stable system for transient packaging of retroviruses
-
Morita S, Kojima T, Kitamura T. Plat-E, an efficient and stable system for transient packaging of retroviruses. Gene Ther. 2000; 7: 1063-6.
-
(2000)
Gene Ther
, vol.7
, pp. 1063-1066
-
-
Morita, S.1
Kojima, T.2
Kitamura, T.3
-
22
-
-
33646253672
-
Akt signaling and cancer: Surviving but not moving on
-
Toker A, Yoeli-Lerner M. Akt signaling and cancer: Surviving but not moving on. Cancer Res. 2006; 66: 3963-6.
-
(2006)
Cancer Res
, vol.66
, pp. 3963-3966
-
-
Toker, A.1
Yoeli-Lerner, M.2
-
23
-
-
0033613226
-
Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats
-
Iruela-Arispe ML, Lombardo M, Krutzsch HC, Lawler J, Roberts DD. Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats. Circulation. 1999; 100: 1423-31.
-
(1999)
Circulation
, vol.100
, pp. 1423-1431
-
-
Iruela-Arispe, M.L.1
Lombardo, M.2
Krutzsch, H.C.3
Lawler, J.4
Roberts, D.D.5
-
24
-
-
10344220521
-
Endogenous angiogenesis inhibitors
-
Folkman J. Endogenous angiogenesis inhibitors. APMIS. 2004; 112: 496-507.
-
(2004)
APMIS
, vol.112
, pp. 496-507
-
-
Folkman, J.1
-
25
-
-
0035122537
-
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis
-
Skobe M, Hawighorst T, Jackson DG et al. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med. 2001; 7: 192-8.
-
(2001)
Nat Med
, vol.7
, pp. 192-198
-
-
Skobe, M.1
Hawighorst, T.2
Jackson, D.G.3
-
26
-
-
34247892352
-
Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis
-
Kopfstein L, Veikkola T, Djonov VG et al. Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis. Am J Pathol. 2007; 170: 1348-61.
-
(2007)
Am J Pathol
, vol.170
, pp. 1348-1361
-
-
Kopfstein, L.1
Veikkola, T.2
Djonov, V.G.3
-
27
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Muller A, Homey B, Soto H et al. Involvement of chemokine receptors in breast cancer metastasis. Nature. 2001; 410: 50-6.
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
-
29
-
-
34247527730
-
Hypoxia-inducible factors, stem cells, and cancer
-
Keith B, Simon MC. Hypoxia-inducible factors, stem cells, and cancer. Cell. 2007; 129: 465-72.
-
(2007)
Cell
, vol.129
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
30
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C, Poppleton H, Kocak M et al. A perivascular niche for brain tumor stem cells. Cancer Cell. 2007; 11: 69-82.
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
-
31
-
-
27144557960
-
A tumorigenic subpopulation with stem cell properties in melanomas
-
Fang D, Nguyen TK, Leishear K et al. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res. 2005; 65: 9328-37.
-
(2005)
Cancer Res
, vol.65
, pp. 9328-9337
-
-
Fang, D.1
Nguyen, T.K.2
Leishear, K.3
-
32
-
-
2542612840
-
Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes
-
Kawada K, Sonoshita M, Sakashita H et al. Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes. Cancer Res. 2004; 64: 4010-7.
-
(2004)
Cancer Res
, vol.64
, pp. 4010-4017
-
-
Kawada, K.1
Sonoshita, M.2
Sakashita, H.3
-
33
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
-
Menendez JA, Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer. 2007; 7: 763-77.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
34
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer. 2004; 4: 891-9.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
35
-
-
4744372082
-
Evolution of the Fgf and Fgfr gene families
-
Itoh N, Ornitz DM. Evolution of the Fgf and Fgfr gene families. Trends Genet. 2004; 20: 563-9.
-
(2004)
Trends Genet
, vol.20
, pp. 563-569
-
-
Itoh, N.1
Ornitz, D.M.2
-
36
-
-
34250223124
-
Physiology. Sister act
-
Moore DD. Physiology. Sister act. Science. 2007; 316: 1436-8.
-
(2007)
Science
, vol.316
, pp. 1436-1438
-
-
Moore, D.D.1
-
37
-
-
42049084378
-
Actions and mode of actions of FGF19 subfamily members
-
Fukumoto S. Actions and mode of actions of FGF19 subfamily members. Endocr J. 2008; 55: 23-31.
-
(2008)
Endocr J
, vol.55
, pp. 23-31
-
-
Fukumoto, S.1
-
38
-
-
34347220473
-
Defining the role of mTOR in cancer
-
Guertin DA, Sabatini DM. Defining the role of mTOR in cancer. Cancer Cell. 2007; 12: 9-22.
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
39
-
-
3042642312
-
Kigamicin D, a novel anticancer agent based on a new anti-austerity strategy targeting cancer cells'tolerance to nutrient starvation
-
Lu J, Kunimoto S, Yamazaki Y, Kaminishi M, Esumi H. Kigamicin D, a novel anticancer agent based on a new anti-austerity strategy targeting cancer cells'tolerance to nutrient starvation. Cancer Sci. 2004; 95: 547-52.
-
(2004)
Cancer Sci
, vol.95
, pp. 547-552
-
-
Lu, J.1
Kunimoto, S.2
Yamazaki, Y.3
Kaminishi, M.4
Esumi, H.5
-
40
-
-
18144399578
-
mTOR-targeted therapy of cancer with rapamycin derivatives
-
Vignot S, Faivre S, Aguirre D, Raymond E. mTOR-targeted therapy of cancer with rapamycin derivatives. Ann Oncol. 2005; 16: 525-37.
-
(2005)
Ann Oncol
, vol.16
, pp. 525-537
-
-
Vignot, S.1
Faivre, S.2
Aguirre, D.3
Raymond, E.4
-
41
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
Hudes G, Carducci M, Tomczak P et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med. 2007; 356: 2271-81.
-
(2007)
N Engl J Med
, vol.356
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
|