Radiation therapy for canine appendicular osteosarcoma

Veterinary and Comparative Oncology

Volumn 7, Issue 1, 2009, Pages 15-27

  Coomer, A ^a   Farese, J ^a   Milner, R ^a   Liptak, J ^b   Bacon, N ^a   Lurie, D ^a  

^a University of Florida   (United States)

^b VCA Canada Alta Vista Animal Hospital   (Canada)

Author keywords

Oncology; Radiation oncology; Small animal; Small animal internal medicine; Surgical oncology

Indexed keywords

RADIOPHARMACEUTICAL AGENT;

ANIMAL; ANIMAL DISEASE; BONE TUMOR; DOG; DOG DISEASE; LIMB; METHODOLOGY; OSTEOSARCOMA; PALLIATIVE THERAPY; RADIOTHERAPY; REVIEW; TREATMENT OUTCOME;

ANIMALS; BONE NEOPLASMS; DOG DISEASES; DOGS; EXTREMITIES; OSTEOSARCOMA; PALLIATIVE CARE; RADIOPHARMACEUTICALS; RADIOTHERAPY; TREATMENT OUTCOME;

ANIMALIA;

EID: 65349173914     PISSN: 14765810     EISSN: 14765829     Source Type: Journal    
DOI: 10.1111/j.1476-5829.2008.00177.x     Document Type: Review

References (60)

1. Liptak JM, Dernell WS, Ehrhart N, Withrow SJ. Canine appendicular osteosarcoma: Diagnosis and palliative treatment. Compendium on Continuing Education for the Practicing Veterinarian 2004; 26: 172-183.
2. Endicott M. Principles of treatment for osteosarcoma. Clinical Techniques in Small Animal Practice 2003; 18: 110-114.
3. Walter CU, Dernell WS, LaRue SE, Lana SE, Lafferty MH, LaDue TA, Withrow SJ. Curative-intent radiation therapy as a treatment modality for appendicular and axial osteosarcoma: A preliminary retrospective evaluation of 14 dogs with the disease. Veterinary and Comparative Oncology 2005; 3: 1-7.
4. Dernell WS, Straw RC and Withrow SJ. Tumors of the skeletal system. In: Small Animal Oncology. SJ Withrow and EG MacEwen, eds., Philidelphia, WB Saunders, 2001: 378-417.
5. Liptak JM, Dernell WS, Ehrhart N, Withrow SJ, Seguin B, Walsh PJ, Kuntz CA. Canine appendicular osteosarcoma: Curative intent treatment. Compendium on Continuing Education for the Practicing Veterinarian 2004; 26: 186-197.
6. Spodnick GJ, Berg J, Rand WM, Schelling SH, Cuoto G, Harvey J, Henderson RA, MacEwen G, Mauldin N, McCaw DL, Moore AS, Morrison W, Norris AM, O'brandovich J, O'Keefe DA, Page R, Ruslander D, Klausner J, Straw RC, Thompson JP, Withrow SJ. Prognosis for dogs with appendicular osteosarcoma treated by amputation alone: 162 cases (1978-1988). Journal of the American Veterinary Medical Association 1992; 200: 995-999.
7. Shapiro W, Fossum TW, Kitchell BE, Cuoto CG, Theilen GH. Use of cisplatin for treatment of appendicular osteosarcoma in dogs. Journal of the American Veterinary Medical Association 1988; 192: 507-511.
8. Maudlin GN, Matus RE, Withrow SJ, Patnaik AK. Canine osteosarcoma: treatment by amputation versus amputation and adjuvant chemotherapy using doxorubicin and cisplatin. Journal of Veterinary Internal Medicine 1988; 2: 177-180.
9. Straw RC, Withrow SJ, Richter SL, Powers BE, Klein MK, Postorino NC, LaRue SM, Ogilvie GK, Vail DM, Morrison WB, McGee M, Dickinson K. Amputation and cisplatin for treatment of canine osteosarcoma. Journal of Veterinary Internal Medicine 1991; 5: 205-210.
10. Thompson JP and Fugent MJ. Evaluation of survival times after limb amputation, with and without subsequent administration of cisplatin, for treatment of appendicular osteosarcoma in dogs: 30 cases. Journal of the American Veterinary Medical Association 1992; 200: 531-533.
11. Bergman PJ, MacEwen EG, Kurzman ID, Henry CJ, Hammer AS, Knapp DW, Hale A, Kruth SA, Klein MK, Klausner J, Norris AM, McCaw D, Straw RC, Withrow SJ. Amputation and carboplatin for treatment of dogs with osteosarcoma: 48 cases (1991 to 1993). Journal of Veterinary Internal Medicine 1996; 10: 76-81.
12. Chun R, Garrett LD, Henry C, Wall M, Smith A. Cisplatin and doxorubicin combination for the treatment of canine osteosarcoma. In: Proceedings of the 18th Annual Veterinary Cancer Society Conference, Vol. 21. 2001: 7.
13. Berg J, Weinstein MJ, Schelling SH, Rand WM. Treatment of dogs with osteosarcoma by administration of cisplatin after amputation or limb-sparing surgery: 22 cases (1987-1990). Journal of the American Veterinary Medical Association 1992; 200: 2005-2008.
14. Berg J, Weinstein MJ, Springfield DS, Rand WM. Results of surgery and doxorubicin chemotherapy in dogs with osteosarcoma. Journal of the American Veterinary Medical Association 1995; 206: 1555-1560.
15. Berg J, Gebhardt MC and Rand WM. Effect of timing of postoperative chemotherapy on survival of dogs with osteosarcoma. Cancer 1997; 79: 1343-1350.
16. Liptak JM, Dernell WS, Lascelles BDX. Survival analysis of dogs with appendicular osteosarcoma treated with limb sparing surgery and adjuvant carboplatin or carboplatin and doxorubicin. In: Proceedings of the 18th Annual Veterinary Cancer Society Conference, Vol. 21. 2001: 39.
17. Bailey D, Erb H, Williams L, Ruslander D, Hauck M. Carboplatin and doxorubicin combination chemotherapy for the treatment of appendicular osteosarcoma in the dog. Journal of Veterinary Internal Medicine 2003; 17: 199-205.
18. Liptak JM, Dernell WS, Lascelles BD, Larue SM, Jameson VJ, Powers BE, Huber DJ, Withrow SJ. Intraoperative extracorporeal irradiation for limb sparing in 13 dogs. Veterinary Surgery 2004; 33: 446-456.
19. Liptak JM, Pluhar GE, Dernell WS, Withrow SJ. Limb-sparing surgery in a dog with osteosarcoma of the proximal femur. Veterinary Surgery 2005; 34: 71-77.
20. Liptak JM, Dernell WS, Straw RC, Jameson VJ, Lafferty MH, Rizzo SA, Withrow SJ. Intercalary bone grafts for joint and limb preservation in 17 dogs with high-grade malignant tumors of the diaphysis. Veterinary Surgery 2004; 33: 457-467.
21. Liptak JM, Dernell WS, Ehrhart N, Lafferty MH, Monteith GJ, Withrow SJ. Cortical allograft and endoprosthesis for limb-sparing surgery in dogs with distal radial osteosarcoma: A prospective clinical comparison of two different limb-sparing techniques. Veterinary Surgery 2006; 35: 518-533.
22. LaRue SM, Withrow SJ, Powers BE, Wrigley RH, Gilette EL, Schwarz PD, Straw RC, Richter SL. Limb-sparing treatment for osteosarcoma in dogs. Journal of the American Veterinary Medical Association 1989; 195: 1734-1744.
23. Morello E, Buracco P, Martano M, Peirone B, Capurro C, Valazza A, Cotto D, Ferracini R, Sora M. Bone allografts and adjuvant cisplatin for the treatment of canine appendicular osteosarcoma in 18 dogs. Journal of Small Animal Practice 2001; 42: 61-66.
24. Buracco P, Morello E, Martano M, Vasconi ME. Pasteurized tumoral autograft as a novel procedure for limb sparing in the dog: A clinical report. Veterinary Surgery 2002; 31: 525-532.
25. Degna MT, Ehrhart N, Feretti A, Buracco P. Bone transport osteogenesis for limb salvage following resection of primary bone tumors: Experience with six cases (1991-1996). Veterinary and Comparative Orthopaedics and Traumatology 2000; 13: 18-22.
26. Ehrhart N. Longitudinal bone transport for treatment of primary bone tumors in dogs: Technique description and outcome in 9 dogs. Veterinary Surgery 2005; 34: 24-34.
27. Boston SE, Duerr F, Bacon N, Larue S, Ehrhart EJ, Withrow SJ. Intraoperative radiation for limb sparing of the distal aspect of the radius without transcarpal plating in five dogs. Veterinary Surgery 2007; 36: 314-323.
28. Farese JP, Milner R, Thompson MS, Lester N, Cooke K, Fox L, Hester J, Bova FJ. Stereotactic radiosurgery for treatment of osteosarcomas involving the distal portions of the limbs in dogs. Journal of the American Veterinary Medical Association 2004; 225: 1567-1572; 1548.
29. Kuntz CA, Asselin TL, Dernell WS, Powers BE, Straw RC, Withrow SJ. Limb salvage surgery for osteosarcoma of the proximal humerus: Outcome in 17 dogs. Veterinary Surgery 1998; 27: 417-422.
30. Lascelles BD, Dernell WS, Correa MT, Lafferty M, Devitt CM, Kuntz CA, Straw RC, Withrow SJ. Improved survival associated with postoperative wound infection in dogs treated with limb-salvage surgery for osteosarcoma. Annals of Surgical Oncology 2005; 12: 1073-1083.
31. McEntee MC. Radiation therapy in the management of bone tumors. Veterinary Clinics of North America Small Animal Practice 1997; 27: 131-138.
32. Green EM, Adams WM and Forrest LJ. Four fraction palliative radiotherapy for osteosarcoma in 24 dogs. Journal of the American Animal Hospital Association 2002; 38: 445-451.
33. Ramirez O III, Dodge RK, Page RL, Price GS, Hauck ML, LaDue TA, Nutter F, Thrall DE. Palliative radiotherapy of appendicular osteosarcoma in 95 dogs. Veterinary Radiology & Ultrasound 1999; 40: 517-522.
34. McEntee MC, Page RL, Novotney CA, Thrall DE. Palliative radiotherapy for canine appendicular osteosarcoma. Veterinary Radiology & Ultrasound 1993; 34: 367-370.
35. Thrall DE and LaRue SM. Palliative radiation therapy. Seminars in Veterinary Medicine & Surgery (Small Animal) 1995; 10: 205-208.
36. Boston SE, Ehrhart NP, Dernell WS, Lafferty M, Withrow SJ. Evaluation of survival time in dogs with stage III osteosarcoma that undergo treatment: 90 cases (1985-2004). Journal of the American Veterinary Medical Association 2006; 228: 1905-1908.
37. Farrelly J and McEntee MC. Principles and applications of radiation therapy. Clinical Techniques in Small Animal Practice 2003; 18: 82-87.
38. Vakaet LA and Boterberg T. Pain control by ionizing radiation of bone metastasis. International Journal of Developmental Biology 2004; 48: 599-606.
39. Goblirsch MJ, Zwolak P and Clohisy DR. Advances in understanding bone cancer pain. Journal of Cellular Biochemistry 2005; 96: 682-688.
40. Mayer MN and Grier CK. Palliative radiation therapy for canine osteosarcoma. Canadian Veterinary Journal 2006; 47: 707-709.
41. Mueller F, Poirier V, Melzer K, Nitzl D, Roos M, Kaser-Hotz B. Palliative radiotherapy with electrons of appendicular osteosarcoma in 54 dogs. In Vivo 2005; 19: 713-716.
42. Bateman KE, Catton PA, Pennock PW, Kruth SA. 0-7-21 radiation therapy for the palliation of advanced cancer in dogs. Journal of Veterinary Internal Medicine 1994; 8: 394-399.
43. Deacon J, Peckham MJ and Steel GG. The radio responsiveness of human tumors and the initial slope of the cell survival curve. Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology 1984; 2: 317-323.
44. Withrow SJ, Powers BE, Straw RD, Thrall DE, Gillette EL, LaRue SM, Richter SL. Tumor necrosis following radiation therapy and/or chemotherapy for canine osteosarcoma. La Chirurgia Degli Organi Di Movimento 1990; 75: 29-31.
45. Powers BE, Withrow SJ, Thrall DE, Straw RC, LaRue SM, Page RL, Gillette EL. Percent tumor necrosis as a predictor of treatment response in canine osteosarcoma. Cancer 1991; 67: 126-134.
46. Withrow SJ, Thrall DE, Straw RC, Powers BE, Wrigley RH, Larue SM, Page RL, Richardson DC, Bissonette KW, Betts CW, DeYoung DJ, Richter SL, Jameson VJ, George SL, Dodge R, Gillette EL, Douple EB. Intra-arterial cisplatin with or without radiation in limb-sparing for canine osteosarcoma. Cancer 1993; 71: 2484-2490.
47. Heidner GL, Page RL, McEntee MC, Dodge RK, Thrall DE. Treatment of canine appendicular osteosarcoma using cobalt 60 radiation and intraarterial cisplatin. Journal of Veterinary Internal Medicine 1991; 5: 313-316.
48. Lana SE, Dernell WS, LaRue SM, Lafferty MH, Douple EB, Brekke JH, Withrow SJ. Slow release cisplatin combined with radiation for the treatment of canine nasal tumors. Veterinary Radiology & Ultrasound 1997; 38: 474-478.
49. Fitzpatrick CL, Farese JP, Milner RJ, Salute ME, Rajon DA, Morris CG, Bova FJ, Lurie DM, Siemann DW. Intrinsic radiosensitivity and repair of sublethal damage in canine osteosarcoma cell lines. American Journal of Veterinary Research 2008; 69: 1197-1202.
50. Nagashima T, Yamamuro T, Kotoura Y, Takahashi M, Abe M, Nakashima Y. Histological studies of the effect of intra-operative irradiation on osteosarcoma. Nippon Seikeigeka Gakkai Zasshi 1983; 57: 1681-1697.
51. Fowler JF. The linear-quadratic formula and progress in fractionated radiotherapy. British Journal of Radiology 1989; 62: 679-694.
52. Kinsella TJ and Sindelar WF. Normal tissue tolerance to intraoperative radiation therapy. Experimental and clinical studies. Frontiers of Radiation Therapy and Oncology 1989; 23: 202-214.
53. Takahashi S, Sugimoto M, Kotoura Y, Oka M, Sasai K, Abe M, Yamamuro T. Long-lasting tolerance of articular cartilage after experimental intraoperative radiation in rabbits. Clinical Orthopaedics and Related Research 1992; 275: 300-305.
54. Ketring AR. 153Sm-EDTMP and 186Re-HEDP as bone therapeutic radiopharmaceuticals. International Journal of Radiation Applications and Instrumentation Part B 1987; 14: 223-232.
55. Barnard SM, Zuber RM and Moore AS. Samarium Sm 153 lexidronam for the palliative treatment of dogs with primary bone tumors: 35 cases (1999-2005). Journal of the American Veterinary Medical Association 2007; 230: 1877-1881.
56. Lattimer JC, Corwin LA Jr, Stapleton J, Volkert WA, Ehrhardt GJ, Ketring AR, Anderson SK, Simon J, Goeckeler WF. Clinical and clinicopathologic response of canine bone tumor patients to treatment with samarium-153-EDTMP. Journal of Nuclear Medicine 1990; 31: 1316-1325.
57. Lattimer JC, Corwin LA Jr, Stapleton J, Volkert WA, Ehrhardt GJ, Ketring AR, Hewett JE, Simon J, Goeckeler WF. Clinical and clinicopathologic effects of samarium-153-EDTMP administered intravenously to normal beagle dogs. Journal of Nuclear Medicine 1990; 31: 586-593.
58. Milner RJ, Dormehl I, Louw WK, Croft S. Targeted radiotherapy with Sm-153-EDTMP in nine cases of canine primary bone tumours. Journal of the South African Veterinary Association 1998; 69: 12-17.
59. Aas M, Moe L, Gamlem H, Skretting A, Ottesen N, Bruland OS. Internal radionuclide therapy of primary osteosarcoma in dogs, using 153Sm-ethylene-diamino-tetramethylene-phosphonate (EDTMP). Clinical Cancer Research 1999; 5: 3148s-3152s.
60. Ehrhart NP, Dernell WS, Withrow SJ, Steyn P, Anderson PM. Targeted internal radiotherapy for osteosarcoma: Isolated limb perfusion using a bone seeking radiopharmaceutical (153Sm-EDTMP). In: Proceedings for the 97th American Association for Cancer Research Annual Meeting. Washington, 2006: 978.