Determination of bergenin in human plasma after oral administration by HPLC-MS/MS method and its pharmacokinetic study

Biomedical Chromatography

Volumn 23, Issue 2, 2009, Pages 199-203

  Wang, Jin ^a   Wang, Ben Jie ^b   Wei, Chun Min ^b   Yuan, Gui Yan ^b   Zhang, Rui ^b   Liu, Hui ^b   Zhang, Xiu Mei ^a   Guo, Rui Chen ^b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Bergenin; HPLC MS MS; Pharmacokinetics; Thiamphenicol

Indexed keywords

ANTIBIOTICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NEGATIVE IONS; PLASMA (HUMAN);

BERGENIN; ETHYL-ACETATE; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; HPLC-MS-MS; HUMAN PLASMAS; INTERNAL STANDARDS; ORAL ADMINISTRATION; PHARMACOKINETIC STUDIES; SIMPLE++; THIAMPHENICOL;

PHARMACOKINETICS;

ACETIC ACID ETHYL ESTER; ACETONITRILE; BERGENIN; THIAMPHENICOL; WATER;

ADULT; ARTICLE; CALIBRATION; CHINESE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; IONIZATION; MALE; MAXIMUM PLASMA CONCENTRATION; NEGATIVE ION ELECTROSPRAY; NORMAL HUMAN; PRECURSOR; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; STRUCTURE ANALYSIS; TABLET FORMULATION; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

EID: 65349172549     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1106     Document Type: Article

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