Selective vagal denervation of the sinus and atrioventricular nodes, guided by vagal reflexes induced by high frequency stimulation, to treat refractory neurally mediated syncope

Journal of Cardiovascular Electrophysiology

Volumn 20, Issue 5, 2009, Pages 558-563

  Scanavacca, Mauricio ^a   Hachul, Denise ^a   Pisani, Cristiano ^a   Sosa, Eduardo ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Autonomic nervous system; Cardiac mapping three dimensional systems; Catheter ablation; Head up tilt testing; Heart rate variability; Neurally mediated syncope

Indexed keywords

ADOLESCENT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CASE REPORT; FEMALE; HEART ATRIOVENTRICULAR NODE; HEART ATRIUM SEPTUM; HUMAN; PRIORITY JOURNAL; QUALITY OF LIFE; RADIOFREQUENCY; SINUS NODE; SYNCOPE; TILT TABLE TEST; VAGOTOMY; VAGUS NERVE; VAGUS NERVE STIMULATION; VAGUS REFLEX; WENCKEBACH PERIOD;

EID: 65349163559     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2008.01385.x     Document Type: Article

References (12)

1. Kapoor WN : Syncope. N Engl J Med 2000 343 : 1856 1862.
2. Grubb BP : Neurocardiogenic syncope. N Engl J Med 2005 352 : 1004 1010.
3. Epstein AE, DiMarco JP, Ellenbogen KA, Estes NAM III., Freedman RA, Gettes LS, Gillinov AM, Gregoratos G, Hammill SC, Hayes DL, Hlatky MA, Newby LK, Page RL, Schoenfeld MH, Silka MJ, Stevenson LW, Sweeney MO : ACC/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: Executive summary: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices). Circulation 2008 117 : 2820 2840.
4. Pachon JC, Pachon EI, Pachon JC, Lobo TJ, Pachon MZ, Vargas RN, Jatene AD : "Cardioneuroablation"- New treatment for neurocardiogenic syncope, functional AV block and sinus dysfunction using catheter RF-ablation. Europace 2005 7 : 1 13.
5. Scherlag BJ, Nakagawa H, Jackman WM, Yamanashi WS, Patterson E, Po S, Lazzara R : Electrical stimulation to identify neural elements on the heart: Their role in atrial fibrillation. J Interv Card Electrophysiol 2005 13 (Suppl 1 37 42.
6. Scanavacca M, Pisani CF, Hachul D, Lara S, Hardy C, Darrieux F, Trombetta I, Negrão CE, Sosa E : Selective atrial vagal denervation guided by evoked vagal reflex to treat patients with paroxysmal atrial fibrillation. Circulation 2006 114 : 876 885.
7. Pappone C, Santinelli V, Manguso F, Vicedomini G, Gugliotta F, Augello G, Mazzone P, Tortoriello V, Landoni G, Zangrillo A, Lang C, Tomita T, Mesas C, Mastella E, Alfieri O : Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation. Circulation 2004 109 : 327 334.
8. Verma A, Saliba WI, Lakkireddy D, Burkhardt JD, Cummings JE, Wazni OM, Belden WA, Thal S, Schweikert RA, Martin DO, Tchou PJ, Natale A : Vagal responses induced by endocardial left atrial autonomic ganglion stimulation before and after pulmonary vein antrum isolation for atrial fibrillation. Heart Rhythm 2007 4 : 1177 1182.
9. Hou Y, Scherlag BJ, Lin J, Zhou J, Song J, Zhang Y, Patterson E, Lazzara R, Jackman WM, Po SS : Interactive atrial neural network: Determining the connections between ganglionated plexi. Heart Rhythm 2007 4 : 56 63.
10. Hou Y, Scherlag BJ, Lin J, Zhang Y, Lu Z, Truong K, Patterson E, Lazzara R, Jackman WM, Po SS : Ganglionated plexi modulate extrinsic cardiac autonomic nerve input: Effects on sinus rate, atrioventricular conduction, refractoriness, and inducibility of atrial fibrillation. J Am Coll Cardiol 2007 50 : 61 68.
11. Pisani CF, Hachul D, Macatrão-Costa M, Lara S, Grupi C, Hardy C, Darrieux F, Sosa E, Scanavacca MI : Long-term autonomic evaluation in patients undergoing selective vagal denervation to treat paroxysmal atrial fibrillation. Heart Rhythm 2007 4 : S65 S65.
12. Thompson GW, Collier K, Ardell JL, Kember G, Armour JA : Functional interdependence of neurons in a single canine intrinsic cardiac ganglionated plexus. J Physiol 2000 528 561 571.