Heme oxygenase-1 mediates the anti-inflammatory effect of isoflurane preconditioning in LPS-stimulated macrophages

Acta Pharmacologica Sinica

Volumn 30, Issue 2, 2009, Pages 228-234

  Li, Qi Fang ^a   Zhu, Ye Sen ^a   Jiang, Hong ^a   Xu, Hui ^a   Sun, Yu ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Anesthesia; Heme oxygenase; Inflammation; Lipopolysaccharide

Indexed keywords

BETA ACTIN; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOFLURANE; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; INHALATION ANESTHETIC AGENT; NITRIC OXIDE; NITRITE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ASSAY; ENZYME RELEASE; IMMUNE RESPONSE; INFLAMMATION; INHALATION ANESTHESIA; MACROPHAGE; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECT; GENETICS; IMMUNOLOGY; METABOLISM;

ANESTHETICS, INHALATION; ANIMALS; CELL LINE; HEME OXYGENASE-1; INFLAMMATION; ISOFLURANE; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 65349162094     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2008.19     Document Type: Article

References (23)

1. Barry U, Zuo Z. Opioids: old drugs for potential new applications. Curr Pharm Design 2005; 11: 1343-50.
2. Zheng S, Zuo Z. Isoflurane preconditioning induces neuroprotection against ischemia via activation of p38 mitogen-activated protein kinases. Mol Pharmacol 2004; 65: 1172-80.
3. Zheng S, Zuo Z. Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebellar slices. Brain Res 2005; 1054: 143-51.
4. Plachinta RV, Hayes JK, Cerilli LA, Rich GF. Isoflurane pretreatment inhibits lipopolysaccharide-induced inflammation in rats. Anesthesiology 2003; 98: 89-95.
5. Reutershan J, Chang D, Hayes JK, Ley K. Protective effects of isoflurane pretreatment in endotoxin-induced lung injury. Anesthesiology 2006; 104: 511-7.
6. Xu X, Feng J, Zuo Z. Isoflurane preconditioning reduces the rat NR8383 macrophage injury induced by lipopolysaccharide and interferon gamma. Anesthesiology 2008; 108: 643-50.
7. Otterbein LE, Choi AM. Heme oxygenase: colors of defense against cellular stress. Am J Physiol 2000; 279: L1029-37.
8. Otterbein LE. Carbon monoxide: innovative anti-inflammatory properties of an age-old gas molecule. Antioxid Redox Signal 2002; 4: 309-19.
9. Li QF, Wang XR, Yang YW, Su DS. Up-regulation of hypoxia inducible factor 1alpha by isoflurane in Hep3B cells. Anesthesiology 2006; 105: 1211-9.
10. Li Q, Zhu Y, Jiang H, Xu H, Liu H. Up-regulation of heme oxygenase-1 by isoflurane preconditioning during tolerance against neuronal injury induced by oxygen glucose deprivation. Acta Biochim Biophys Sin 2008; 40: 803-10.
11. Hoetzel A, Leitz D, Schmidt R, Tritschler E, Bauer I, Loop T, et al. Mechanism of hepatic heme oxygenase-1 induction by isoflurane. Anesthesiology 2006; 104: 101-9.
12. Schmidt R, Tritschler E, Hoetzel A, Loop T, Humar M, Halverscheid L, et al. Heme oxygenase-1 induction by the clinically used anesthetic isoflurane protects rat livers from ischemia/ reperfusion injury. Ann Surg 2007; 245: 931-42.
13. Otterbein LE, Bach FH, Alam J, Soares M, Tao Lu H, Wysk M, et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med 2000; 6: 422-8.
14. Otterbein LE, Soares MP, Yamashita K, Bach FH. Heme oxygenase-1: unleashing the protective properties of heme. Trends Immunol 2003; 24 : 449-55.
15. Wagener FA, Volk HD, Willis D, Abraham NG, Soares MP, Adema GJ, et al. Different faces of the heme-heme oxygenase system in inflammation. Pharmacol Rev 2003; 55: 551-71.
16. Sawle P, Foresti R, Mann BE, Johnson TR, Green CJ, Motterlini R. Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages. Br J Pharmacol 2005; 145: 800-10.
17. Li QF, Wang XR, Yang YW, Lin H. Hypoxia upregulates hypoxia inducible factor (HIF)-3alpha expression in lung epithelial cells: characterization and comparison with HIF-1alpha. Cell Res 2006; 16: 548-58.
18. Foresti R, Clark JE, Green CJ, Motterlini R. Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells. Involvement of superoxide and peroxynitrite anions. J Biol Chem 1997; 272: 18411-7.
19. Camhi SL, Alam J, Wiegand GW, Chin BY, Choi AM. Transcriptional activation of the HO-1 gene by lipopolysaccharide is mediated by 5' distal enhancers: role of reactive oxygen intermediates and AP-1. Am J Respir Cell Mol Biol 1998; 18: 226-34.
20. Tracey KJ, Cerami A. Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Ann Rev Med 1994; 45: 491-503.
21. Bak I, Papp G, Turoczi T, Varga E, Szendrei L, Vecsernyes M, et al. The role of heme oxygenase-related carbon monoxide and ventricular fibrillation in ischemic/reperfused hearts. Free Radic Biol Med 2002; 33: 639-48.
22. Bak I, Szendrei L, Turoczi T, Papp G, Joo F, Das DK, et al. Heme oxygenase-1-related carbon monoxide production and ventricular fibrillation in isolated ischemic/reperfused mouse myocardium. FASEB J 2003; 17: 2133-5.
23. Zuo Z, Johns RA. Inhalational anesthetics up-regulate constitutive and lipopolysaccharide-induced inducible nitric oxide synthase expression and activity. Mol Pharmacol 1997; 52: 606-12.