Synthesis and biological evaluation of a novel 99mTc nitrido radiopharmaceutical with deoxyglucose dithiocarbamate, showing tumor uptake

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 10, 2009, Pages 2752-2754

  Zhang, Junbo ^a   Ren, Jialei ^a   Lin, Xiao ^a   Wang, Xuebin ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

Author keywords

2 Amino 2 deoxy d glucose; 99mTc nitrido complex; Dithiocarbamate; Tumor imaging

Indexed keywords

2 AMINO 2 DEOXY DEXTRO GLUCOSE DITHIOCARBAMATE TC 99M; DIETHYLENETRIAMINE PENTAACETATE DEOXYGLUCOSE TC 99M; ETHYLENE DICYSTEINE DEOXYGLUCOSE TC 99M; FLUORODEOXYGLUCOSE F 18; MERCAPTOACETYLTRIGLYCINE DEOXYGLUCOSE TC 99M; MONOAMINE MONOAMIDE DITHIOL BUTYRIC ACID DEOXYGLUCOSE TC 99M; RADIOPHARMACEUTICAL AGENT; SESTAMIBI DEOXYGLUCOSE TC 99M; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; DECOMPOSITION; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG SCREENING; DRUG SYNTHESIS; DRUG TUMOR LEVEL; ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; PARTITION COEFFICIENT; RADIOCHEMISTRY; ROOM TEMPERATURE; THIN LAYER CHROMATOGRAPHY;

ANIMALS; CARBAMATES; DEOXYGLUCOSE; ISOTOPE LABELING; MICE; NEOPLASMS; ORGANOTECHNETIUM COMPOUNDS; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION;

MUS;

EID: 65349157029     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.03.131     Document Type: Article

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