Neuroanatomical mapping of rabies nucleocapsid viral antigen distribution and apoptosis in pathogenesis in street dograbies - An immunohistochemical study

Clinical Neuropathology

Volumn 28, Issue 2, 2009, Pages 113-124

  Suja, M S ^a   Mahadevan, A ^a   Madhusudhana, S N ^a   Vijayasarathi, S K ^b   Shankar, S K ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^b VETERINARY COLLEGE   (India)

Author keywords

Canine brain; Immunocytochemistry; Neuroanatomy; Nucleocapsid antigen; Rabies street virus

Indexed keywords

VIRUS ANTIGEN; ACETYLCHOLINE; NUCLEOCAPSID PROTEIN; NUCLEOCAPSID PROTEIN, RABIES VIRUS;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CLINICAL FEATURE; CONTROLLED STUDY; DENDRITE; DNA FRAGMENTATION; DOG; HOST PATHOGEN INTERACTION; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; LIMBIC CORTEX; NERVE FIBER; NEUROANATOMY; NEUROPATHOLOGY; NICK END LABELING; NONHUMAN; PARASYMPATHETIC INNERVATION; PATHOGENESIS; PERIKARYON; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RABIES; RABIES VIRUS; RETICULAR FORMATION; THALAMUS; TRIGEMINAL NUCLEUS; VAGUS NERVE NUCLEUS; VIRUS NUCLEOCAPSID; ANIMAL; ANIMAL DISEASE; BRAIN; DOG DISEASE; FLUORESCENT ANTIBODY TECHNIQUE; ISOLATION AND PURIFICATION; METABOLISM; MICROGLIA; MOUSE; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; VIROLOGY;

ACETYLCHOLINE; ANIMALS; APOPTOSIS; BRAIN; DNA FRAGMENTATION; DOG DISEASES; DOGS; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MICE; MICROGLIA; NEURONS; NUCLEOCAPSID PROTEINS; RABIES; RABIES VIRUS;

EID: 65349120021     PISSN: 07225091     EISSN: None     Source Type: Journal    
DOI: 10.5414/npp28113     Document Type: Article

References (17)

1. Beamer PD, Mohr CO, Barr TR. Resistance of the opossum to rabies virus. Am J Vet Res. 1960; 21: 507-510.
2. Charlton KM, Casey GA, Wandeler AI, Nadin-Davis S. Early events in rabies virus infection of central nervous system in skunks (Mephitis mephitis). Acta Neuropathol. 1996; 91: 89-98.
3. Dutta JK. Human rabies in India: epidemiological features, management and current methods of prevention. Trop Doct. 1999; 29: 196-201.
4. Fekadu M, Chandler FW, Harrison AK. Pathogenesis of rabies in dogs inoculated with an Ethiopian rabies virus strain. Immunoflourescence, histologic and ultrastructural studies of the central nervous system. Arch Virol. 1982; 71: 109-126.
5. Fekadu M. Pathogenesis of rabies virus infection in dogs. Rev Infect Dis. 1988; 10: 678-683.
6. Hemachudha T, Phanuphak P, Sriwantanthana B, Manutsathit S, Phanthumchinda K, Siriprasomsup W, Ukachoke C, Rasameechan S, Kaoroptham S. Immunologic study of human encephalitic and paralytic rabies. A preliminary study of 16 patients. Am J Med. 1988; 84: 673-677.
7. Hemachudha T, Wacharapluesadee S, Mitrabhakdi E, Wilde H, Morimoto K, Lewis RA. Pathophysiology of human paralytic rabies. J Neurovirol. 2005; 11: 93-100.
8. Lentz TL, Burrage TG, Amith AL, Crick J, Tignor GH. Is the acetylcholine receptor a rabies virus receptor? Science. 1982; 215: 182-184.
9. Mitrabhakdi E, Shuangshoti S, Wannakrairot P, Lewis RA, Susuki K, Laothamatas J, Hemachudha T. Difference in neuropathogenetic mechanisms in human furious and paralytic rabies. J Neurol Sci. 2005; 238: 3-10.
10. Smith JS, Fishbein DB, Rupprecht CE, Clark K. Unexplained rabies in three immigrants in the United States: a virologic investigation. N Engl J Med. 1991; 324: 205-211.
11. Suja MS, Mahadevan A, Madhusudhana SN, Vijayasarathy SK, Shankar SK. Cerebral cysticercosis mimicking rabies in a dog. Vet Rec. 2003; 153: 304-305.
12. Sudarshan MK, Madhusudana SN, Mahendra BJ, Rao NS, Ashwath Narayana DH, Abdul Rahman S, Meslin FX, Lobo D, Ravikumar K, Gangaboraiah. Assessing the burden of human rabies in India: results of a national multi-center epidemiological survey. 2007; 11: 29-35.
13. Theerasurakarn S, Ubol S. Apoptosis induction in brain during the fixed strain of rabies virus infection correlates with onset and severity of illness. J Neurovirol. 1998; 4: 407-414.
14. Tirawatanpong S, Hemachudha T, Manutsathit S et al. Regional distribution of rabies viral in the central nervous system of human encephalic and paralytic rabies. Neurol Science. 1989; 92: 91-99.
15. Thomas WJ. Functional mammalian neuroanatomy - with emphasis on Dog and Cat including an atlas of Dog central nervous system. Philadelphia: Lea and Febiger; 1972. p. 347-403.
16. WHO. Expert consultation on rabies 2005. Technical report series 931. Geneva: WHO; 2005. p. 3.
17. Yan X, Prosnaik M, Curtis MT, Weiss ML, Faber M, Dietzschold B, Fu ZF. Silver-haired bat rabies virus variant does not induce apoptosis in the brain of experimentally infected mice. J Neurovirol. 2001; 7: 518-527.