-
1
-
-
0034595634
-
WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II
-
Xu B, English JM, Wilsbacher JL et al. WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II. J Biol Chem 2000; 275: 16795
-
(2000)
J Biol Chem
, vol.275
, pp. 16795
-
-
Xu, B.1
English, J.M.2
Wilsbacher, J.L.3
-
2
-
-
40449098229
-
WNKkinases and renal sodium transport in health and disease: An integrated view
-
McCormick JA,YangCL, Ellison DH.WNKkinases and renal sodium transport in health and disease: an integrated view. Hypertension 2008; 51: 588
-
(2008)
Hypertension
, vol.51
, pp. 588
-
-
McCormick, J.A.1
Yang, C.L.2
Ellison, D.H.3
-
3
-
-
36048938340
-
The thiazide-sensitive Na-Cl cotransporter is regulated by aWNK kinase signaling complex
-
Yang CL, Zhu X, Ellison DH. The thiazide-sensitive Na-Cl cotransporter is regulated by aWNK kinase signaling complex. J Clin Invest2007; 117: 3403
-
(2007)
J Clin Invest
, vol.117
, pp. 3403
-
-
Yang, C.L.1
Zhu, X.2
Ellison, D.H.3
-
4
-
-
56549094967
-
Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone
-
Chiga M, Rai T, Yang SS et al. Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone. Kidney Int 2008; 74: 1403
-
(2008)
Kidney Int
, vol.74
, pp. 1403
-
-
Chiga, M.1
Rai, T.2
Yang, S.S.3
-
5
-
-
56549099694
-
Regulation of the Na+-Cl-cotransporter by dietary NaCl: A role for WNKs, SPAK, OSR1, and aldosterone
-
Vallon V. Regulation of the Na+-Cl-cotransporter by dietary NaCl: a role for WNKs, SPAK, OSR1, and aldosterone. Kidney Int 2008; 74: 1373
-
(2008)
Kidney Int
, vol.74
, pp. 1373
-
-
Vallon, V.1
-
7
-
-
33748043980
-
Dietary electrolytedriven responses in the renal WNK kinase pathway in vivo
-
O'Reilly M, Marshall E, Macgillivray T et al. Dietary electrolytedriven responses in the renal WNK kinase pathway in vivo. J Am Soc Nephrol 2006; 17: 2402
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2402
-
-
O'Reilly, M.1
Marshall, E.2
Macgillivray, T.3
-
8
-
-
33744811449
-
WNK1 kinase isoform switch regulates renal potassium excretion
-
Wade JB, Fang L, Liu J et al. WNK1 kinase isoform switch regulates renal potassium excretion. Proc Natl Acad Sci U S A 2006; 103: 8558
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 8558
-
-
Wade, J.B.1
Fang, L.2
Liu, J.3
-
9
-
-
31944441600
-
Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms
-
Lazrak A, Liu Z, Huang CL. Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms. Proc Natl Acad Sci USA2006; 103: 1615
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1615
-
-
Lazrak, A.1
Liu, Z.2
Huang, C.L.3
-
10
-
-
12244262811
-
Bartter's, Gitelman's, and Gordon's syndromes. From physiology to molecular biology and back, yet still some unanswered questions
-
Kamel KS, Oh MS, Halperin ML. Bartter's, Gitelman's, and Gordon's syndromes. From physiology to molecular biology and back, yet still some unanswered questions. Nephron 2002; 92(Suppl 1): 18
-
(2002)
Nephron
, vol.92
, Issue.SUPPL. 1
, pp. 18
-
-
Kamel, K.S.1
Oh, M.S.2
Halperin, M.L.3
-
11
-
-
17944373014
-
Human hypertension caused by mutations in WNK kinases
-
Wilson FH, Disse-Nicodeme S, ChoateKAet al.Human hypertension caused by mutations in WNK kinases. Science 2001; 293: 1107
-
(2001)
Science
, vol.293
, pp. 1107
-
-
Wilson, F.H.1
Disse-Nicodeme, S.2
ChoateKA3
-
12
-
-
33749118898
-
Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule
-
Lalioti MD, Zhang J, Volkman HM et al. Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule. Nat Genet 2006; 38: 1124
-
(2006)
Nat Genet
, vol.38
, pp. 1124
-
-
Lalioti, M.D.1
Zhang, J.2
Volkman, H.M.3
-
13
-
-
34247617951
-
Molecular pathogenesis of pseudohypoaldosteronism type II: Generation and analysis of a Wnk4(D561A/+) knock-in mouse model
-
Yang SS, Morimoto T, Rai T et al. Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knock-in mouse model. Cell Metab 2007; 5: 331
-
(2007)
Cell Metab
, vol.5
, pp. 331
-
-
Yang, S.S.1
Morimoto, T.2
Rai, T.3
-
14
-
-
35549003692
-
Mechanisms of disease: WNK-ing at the mechanism of salt-sensitive hypertension
-
Huang CL, Kuo E. Mechanisms of disease: WNK-ing at the mechanism of salt-sensitive hypertension. Nat Clin Pract Nephrol 2007; 3: 623
-
(2007)
Nat Clin Pract Nephrol
, vol.3
, pp. 623
-
-
Huang, C.L.1
Kuo, E.2
-
16
-
-
33646541375
-
Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats
-
Song J, Hu X, Riazi S et al. Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats. Am J Physiol Renal Physiol 2006; 290: F1055
-
(2006)
Am J Physiol Renal Physiol
, vol.290
-
-
Song, J.1
Hu, X.2
Riazi, S.3
-
17
-
-
33644874530
-
Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population
-
Tobin MD, Raleigh SM, Newhouse S et al. Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population. Circulation 2005; 112: 3423
-
(2005)
Circulation
, vol.112
, pp. 3423
-
-
Tobin, M.D.1
Raleigh, S.M.2
Newhouse, S.3
-
18
-
-
55949098688
-
Common variation in the WNK1 gene and blood pressure in childhood: The Avon Longitudinal Study of Parents and Children
-
Tobin MD, Timpson NJ, Wain LV et al. Common variation in the WNK1 gene and blood pressure in childhood: the Avon Longitudinal Study of Parents and Children. Hypertension 2008; 52: 974
-
(2008)
Hypertension
, vol.52
, pp. 974
-
-
Tobin, M.D.1
Timpson, N.J.2
Wain, L.V.3
-
19
-
-
65349096255
-
Whole-genome association study identifies STK39 as a hypertension susceptibility gene
-
Wang Y, O'Connell JR,McArdle PF et al.Whole-genome association study identifies STK39 as a hypertension susceptibility gene. Proc Natl Acad Sci USA 2008
-
(2008)
Proc Natl Acad Sci USA
-
-
Wang, Y.1
O'Connell, J.R.2
McArdle, P.F.3
-
20
-
-
2542427516
-
Geneticism of essential hypertension
-
Luft FC. Geneticism of essential hypertension. Hypertension 2004; 43: 1155
-
(2004)
Hypertension
, vol.43
, pp. 1155
-
-
Luft, F.C.1
-
21
-
-
10744222959
-
The ACE gene I/D polymorphism is not associated with the blood pressure and cardiovascular benefits of ACE inhibition
-
Harrap SB, Tzourio C, Cambien F et al. The ACE gene I/D polymorphism is not associated with the blood pressure and cardiovascular benefits of ACE inhibition. Hypertension 2003; 42: 297
-
(2003)
Hypertension
, vol.42
, pp. 297
-
-
Harrap, S.B.1
Tzourio, C.2
Cambien, F.3
-
22
-
-
0038796602
-
Angiotensinogen single nucleotide polymorphisms, elevated blood pressure, and risk of cardiovascular disease
-
Sethi AA, Nordestgaard BG, Gronholdt ML et al. Angiotensinogen single nucleotide polymorphisms, elevated blood pressure, and risk of cardiovascular disease. Hypertension 2003; 41: 1202
-
(2003)
Hypertension
, vol.41
, pp. 1202
-
-
Sethi, A.A.1
Nordestgaard, B.G.2
Gronholdt, M.L.3
-
23
-
-
49849090255
-
Physiological interaction between alpha-adducin and WNK1-NEDD4L pathways on sodiumrelated blood pressure regulation
-
Manunta P, Lavery G, Lanzani C et al. Physiological interaction between alpha-adducin and WNK1-NEDD4L pathways on sodiumrelated blood pressure regulation. Hypertension 2008; 52: 366
-
(2008)
Hypertension
, vol.52
, pp. 366
-
-
Manunta, P.1
Lavery, G.2
Lanzani, C.3
-
24
-
-
44449116109
-
Increased urinary Na-Cl cotransporter protein in familial hyperkalaemia and hypertension
-
Mayan H, Attar-Herzberg D, Shaharabany M et al. Increased urinary Na-Cl cotransporter protein in familial hyperkalaemia and hypertension. Nephrol Dial Transplant 2008; 23: 492
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 492
-
-
Mayan, H.1
Attar-Herzberg, D.2
Shaharabany, M.3
-
25
-
-
32044437866
-
Urinary prostasin: A candidate marker of epithelial sodium channel activation in humans
-
Olivieri O, Castagna A, Guarini P et al. Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans. Hypertension2005; 46: 683
-
(2005)
Hypertension
, vol.46
, pp. 683
-
-
Olivieri, O.1
Castagna, A.2
Guarini, P.3
-
26
-
-
4444226979
-
Identification and proteomic profiling of exosomes in human urine
-
Pisitkun T, Shen RF, Knepper MA. Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci USA 2004; 101: 13368
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13368
-
-
Pisitkun, T.1
Shen, R.F.2
Knepper, M.A.3
-
27
-
-
49749121101
-
Urinary exosomal transcription factors, a new class of biomarkers for renal disease
-
Zhou H, Cheruvanky A, Hu X et al. Urinary exosomal transcription factors, a new class of biomarkers for renal disease. Kidney Int 2008; 74: 613
-
(2008)
Kidney Int
, vol.74
, pp. 613
-
-
Zhou, H.1
Cheruvanky, A.2
Hu, X.3
-
28
-
-
33750603834
-
Exosomal Fetuin-A identified by proteomics: A novel urinary biomarker for detecting acute kidney injury
-
Zhou H, Pisitkun T, Aponte A et al. Exosomal Fetuin-A identified by proteomics: a novel urinary biomarker for detecting acute kidney injury. Kidney Int 2006; 70: 1847
-
(2006)
Kidney Int
, vol.70
, pp. 1847
-
-
Zhou, H.1
Pisitkun, T.2
Aponte, A.3
-
29
-
-
21344441046
-
Prospects for urinary proteomics: Exosomes as a source of urinary biomarkers
-
Hoorn EJ, Pisitkun T, Zietse R et al. Prospects for urinary proteomics: exosomes as a source of urinary biomarkers. Nephrology (Carlton)2005; 10: 283
-
(2005)
Nephrology (Carlton)
, vol.10
, pp. 283
-
-
Hoorn, E.J.1
Pisitkun, T.2
Zietse, R.3
-
31
-
-
1642323740
-
Protein kinase inhibitors: Insights into drug design from structure
-
Noble ME, Endicott JA, Johnson LN. Protein kinase inhibitors: insights into drug design from structure. Science 2004; 303: 1800
-
(2004)
Science
, vol.303
, pp. 1800
-
-
Noble, M.E.1
Endicott, J.A.2
Johnson, L.N.3
-
32
-
-
10744226663
-
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
-
Zambrowicz BP, Abuin A, Ramirez-Solis R et al. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci USA2003; 100: 14109
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14109
-
-
Zambrowicz, B.P.1
Abuin, A.2
Ramirez-Solis, R.3
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