Delayed renal excretion of methotrexate after a severe anaphylactic reaction to methotrexate in a child with osteosarcoma

Journal of Pediatric Hematology/Oncology

Volumn 31, Issue 4, 2009, Pages 289-291

  Ozguven, Ali Aykan ^a   Uysal, Kamer ^b   Gunes, Dilek ^b   Koroglu, Tolga ^b   Gurcu, Ozlem ^b   Olgun, Nur ^b  

^a CELAL BAYAR UNIVERSITY   (Turkey)

^b DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

Anaphylactic reaction; Delayed excretion; Methotrexate

Indexed keywords

ADRENALIN; CARBOPLATIN; CISPLATIN; CREATININE; DEXAMETHASONE; DIPHENHYDRAMINE; DOBUTAMINE; DOPAMINE; DOXORUBICIN; ETOPOSIDE; FOLINIC ACID; GRANISETRON; IFOSFAMIDE; METHOTREXATE; ANTINEOPLASTIC ANTIMETABOLITE;

ADOLESCENT; ANAPHYLAXIS; ARTICLE; CASE REPORT; CLINICAL FEATURE; CREATININE BLOOD LEVEL; DRUG EXCRETION; DRUG MEGADOSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FACE EDEMA; FEMALE; FEVER; FLUSHING; HUMAN; HYPOTENSION; KIDNEY FAILURE; NEPHROTOXICITY; OSTEOSARCOMA; PRIORITY JOURNAL; SIDE EFFECT; TACHYCARDIA; TREMOR; URINARY EXCRETION; URTICARIA; VOMITING; BONE TUMOR; CHEMICALLY INDUCED DISORDER; HOSPITALIZATION; URINE;

ADOLESCENT; ANAPHYLAXIS; ANTIMETABOLITES, ANTINEOPLASTIC; BONE NEOPLASMS; FEMALE; HUMANS; METHOTREXATE; OSTEOSARCOMA; SEVERITY OF ILLNESS INDEX;

EID: 65349116199     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e318199388c     Document Type: Article

References (20)

1. Shepherd GM. Hypersensitivity reactions to chemotherapeutic drugs. Clin Rev Allergy Immunol. 2003;24:253-262.
2. Mutafoglu-Uysal K, Sarialioglu F, Olgun N. Bleomycin-induced hyperpigmentation and hypersensitivity reactions to etoposide and vinblastine in a child with endodermal sinus tumor. Turk J Pediatr. 2001;43:172-174.
3. Devecioglu O, Biner B, Karabocuoglu M, et al. Systemic near-fatal anaphylactic reaction after intrathecal methotrexate administration. Med Pediatr Oncol. 2000;34:151-152.
4. Vega A, Cabanas R, Contreras J, et al. Anaphylaxis to methotrexate: a possible IgE-mediated mechanism. J Allergy Clin Immunol. 1994;94:268-270.
5. Alkins SA, Byrd JC, Morgan SK, et al. Anaphylactoid reactions to methotrexate. Cancer. 1996;77:2123-2126.
6. MacGinnitie AJ, Walensky LD, Turvey SE, et al. Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge. Pediatr Allergy Immunol. 2003;14:409-411.
7. Postovsky S, Elhasid R, Ben-Barak A, et al. Allergic reaction to high-dose methotrexate. Med Pediatr Oncol. 2000;35:131-132.
8. Bramwell VH, Burgers M, Sneath R, et al. A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: the first study of the European Osteosarcoma Intergroup. J Clin Oncol. 1992;10:1579-1591.
9. Van Winkle P, Angiolillo A, Krailo M, et al. Ifosfamide, carboplatin, and etoposide (ICE) reinduction chemotherapy in a large cohort of children and adolescents with recurrent/ refractory sarcoma: the Children's Cancer Group (CCG) experience. Pediatr Blood Cancer. 2005;44:338-347.
10. Goldberg NH, Romolo JL, Austin EH, et al. Anaphylactoid type reactions in two patients receiving high dose intravenous methotrexate. Cancer. 1978;41:52-55.
11. Elkiran ET, Altundag K, Aksoy S, et al. Systemic anaphylactic reaction following intrathecal administration of methotrexate in adult patient with primary central nervous system lym-phoma. Am J Hematol. 2004;75:265.
12. Straka M, Zeringue E, Goldman M. A rare drug reaction to methotrexate after treatment for ectopic pregnancy. Obstet Gynecol. 2004;103:1047-1048.
13. Houtman PM, Jansen TL, Blanken R. Anaphylactic reaction in a patient with rheumatoid arthritis: a rare side effect of methotrexate with etanercept as a provoking factor? J Clin Rheumatol. 2006;12:321-322.
14. Davis KA, Williams P, Walker JC. Successful desensitization to high-dose methotrexate after systemic anaphylaxis. Ann Allergy Asthma Immunol. 2003;90:87-89.
15. Lluch-Bernal M, Cuesta-Herranz J, De las Heras M, et al. Anaphylactic reaction to methotrexate. Allergy. 1997;52: 1150-1151.
16. Da Costa M, Isacoff W, Rothenberg SP, et al. Protein-methotrexate-IgG complexes in the serum of patients receiving high-dose antifolate therapy. Cancer. 1980;46:471-474.
17. Cohn JR, Cohn JB, Fellin F, et al. Systemic anaphylaxis from low dose methotrexate. Ann Allergy. 1993;70:384-385.
18. Recker DP, Minor JR, Miller FW. Successful prevention of an anaphylactoid reaction to high-dose methotrexate. DICP. 1989; 23:1032.
19. Klimo P, Ibrahim E. Anaphylactic reaction to methotrexate used in high doses as an adjuvant treatment of osteogenic sarcoma. Cancer Treat Rep. 1981;65:725.
20. Al-Lamki Z, Thomas E, el-Banna N, et al. Acute urticaria and hepatitis complicating high-dose methotrexate therapy. Med Pediatr Oncol. 1995;24:137-140.