Characterization of Breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway

NMR in Biomedicine

Volumn 22, Issue 1, 2009, Pages 114-127

  Morse, David L ^a   Carroll, Danielle ^a   Day, Sam ^a   Gray, Heather ^a   Sadarangani, Pooja ^a   Murthi, Shiva ^a   Job, Constantin ^b   Baggett, Brenda ^a   Raghunand, Natarajan ^a   Gillies, Robert J ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Breast; Cancer; Choline; Gene expression; Metabolism; Phosphatidylcholine

Indexed keywords

BIOCHEMICAL MECHANISMS; BIOSYNTHETIC PRECURSORS; BREAKDOWN PRODUCTS; BREAST; BREAST CANCER XENOGRAFTS; BREAST CANCERS; CANCER; CELL LINES; CHOLINE; CYTOSOLIC; DIAGNOSTIC INDICATORS; DIAGNOSTIC TOOLS; DRUG DEVELOPMENT; EX-VIVO; GENE EXPRESSION PROFILING; GENES ENCODING ENZYMES; GLYCEROPHOSPHOCHOLINE; HIGH RESOLUTIONS; IMAGE-GUIDED; IN CELLS; IN-VIVO; KINASE ACTIVITIES; LIPID METABOLITES; LYSOPHOSPHATIDYLCHOLINE; MEMBRANE PHOSPHOLIPIDS; METABOLIC PATHWAYS; METASTATIC TUMORS; MOLECULAR TARGETS; NMR SPECTROSCOPIES; PHOSPHATIDYLCHOLINE; PHOSPHOCHOLINE; PHOSPHOLIPASE A; SINGLE VOXEL; TUMOR MODELS;

BIOACTIVITY; BIOCHEMISTRY; BIOMOLECULES; CELL CULTURE; CELL MEMBRANES; GENE EXPRESSION; GLYCEROL; METABOLITES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOLIPIDS; RECONNAISSANCE AIRCRAFT; TUMORS;

METABOLISM;

CHOLINE; CHOLINE KINASE; DOCETAXEL; GLYCEROPHOSPHATE; GLYCEROPHOSPHORYLCHOLINE; LIPID; LYSOPHOSPHATIDYLCHOLINE; MESSENGER RNA; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A; PHOSPHORYLCHOLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CATABOLISM; ENZYME ACTIVITY; EX VIVO STUDY; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IN VIVO STUDY; METABOLITE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; TREATMENT RESPONSE; TUMOR XENOGRAFT;

ANIMALS; CELL EXTRACTS; CELL LINE, TUMOR; CHOLINE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEOPLASM; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MAMMARY NEOPLASMS, ANIMAL; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, SCID; PHENOTYPE; PHOSPHATIDYLCHOLINES; RNA, MESSENGER; TAXOIDS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 65349109924     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1318     Document Type: Article

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