Differential regulation of human thymosin beta 15 isoforms by transforming growth factor beta 1

Genes Chromosomes and Cancer

Volumn 48, Issue 6, 2009, Pages 502-509

  Banyard, Jacqueline ^a   Barrows, Courtney ^a   Zetter, Bruce R ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; ISOPROTEIN; SMALL INTERFERING RNA; THYMOSIN; THYMOSIN BETA15; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CELL MIGRATION; COLON CANCER; CONTROLLED STUDY; ENZYME REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; CELL MOTION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NEOPLASM; NUCLEOTIDE SEQUENCE; RNA INTERFERENCE; SEQUENCE ALIGNMENT; STATISTICAL ANALYSIS; TUMOR CELL LINE;

BASE SEQUENCE; CELL LINE, TUMOR; CELL MOVEMENT; DATA INTERPRETATION, STATISTICAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASMS; PROTEIN ISOFORMS; RNA INTERFERENCE; SEQUENCE ALIGNMENT; THYMOSIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 65349102898     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20659     Document Type: Article

References (21)

1. Abdulrahman M, Maina EN, Morris MR, Zatyka M, Raval RR, Banks RE, Wiesener MS, Richards FM, Johnson CM, Latif F, Maher ER. 2007. Identification of novel VHL targets that are associated with the development of renal cell carcinoma. Oncogene 26:1661-1672. (Pubitemid 46398734)
2. Banyard J, Symons M. 2002. Cell motility and invasion assays. Methods Mol Biol 189:129-140.
3. Banyard J, Hutchinson LM, Zetter BR. 2007. Thymosin beta-NB is the human isoform of rat thymosin beta15. Ann N Y Acad Sci 1112:286-296. (Pubitemid 47598663)
4. Bao L, Zetter BR. 2000. Molecular cloning and structural characterization of the rat thymosin beta15 gene. Gene 260:37-44. (Pubitemid 32008498)
5. Bao L, Loda M, Janmey PA, Stewart R, Anand-Apte B, Zetter BR. 1996. Thymosin beta 15: A novel regulator of tumor cell motility upregulated in metastatic prostate cancer. Nat Med 2:1322-1328. (Pubitemid 26401734)
6. Bertheau P, Turpin E, Rickman DS, Espie M, de Reynies A, Feugeas JP, Plassa LF, Soliman H, Varna M, de Roquancourt A, Lehmann-Che J, Beuzard Y, Marty M, Misset JL, Janin A, de The H. 2007. Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen. PLoS Med 4:e90. (Pubitemid 46495326)
7. Chakravatri A, Zehr EM, Zietman AL, Shipley WU, Goggins WB, Finkelstein DM, Young RH, Chang EL, Wu CL. 2000. Thymosin beta-15 predicts for distant failure in patients with clinically localized prostate cancer-results from a pilot study. Urology 55:635-638.
8. Choe J, Sun W, Yoon SY, Rhyu IJ, Kim EH, Kim H. 2005. Effect of thymosin beta15 on the branching of developing neurons. Biochem Biophys Res Commun 331:43-49. (Pubitemid 40545139)
9. Conant GC, Wolfe KH. 2008. Turning a hobby into a job: How duplicated genes find new functions. Nat Rev Genet 9:938-950. (Pubitemid 352719432)
10. Dhaese S, Jonckheere V, Goethals M, Waltregny D, Vandekerckhove J, Ampe C, Van Troys M. 2007. Functional and profiling studies prove that prostate cancer upregulated neuroblastoma thymosin beta is the true human homologue of rat thymosin beta15. FEBS Lett 581:4809-4815. (Pubitemid 47531747)
11. Dunfield LD, Dwyer EJ, Nachtigal MW. 2002. TGF beta-induced Smad signaling remains intact in primary human ovarian cancer cells. Endocrinology 143:1174-1181. (Pubitemid 34274344)
12. Gold JS, Bao L, Ghoussoub RA, Zetter BR, Rimm DL. 1997. Localization and quantitation of expression of the cell motility-related protein thymosin beta15 in human breast tissue. Mod Pathol 10:1106-1112. (Pubitemid 27521288)
13. Gu YM, Li SY, Qiu XS, Wang EH. 2008. Elevated thymosin beta15 expression is associated with progression and metastasis of non-small cell lung cancer. Apmis 116:484-490.
14. Hutchinson LM, Chang EL, Becker CM, Ushiyama N, Behonick D, Shih MC, DeWolf WC, Gaston SM, Zetter BR. 2005. Development of a sensitive and specific enzyme-linked immunosorbent assay for thymosin beta15, a urinary biomarker of human prostate cancer. Clin Biochem 38:558-571. (Pubitemid 40693471)
15. Kannan K, Amariglio N, Rechavi G, Jakob-Hirsch J, Kela I, Kaminski N, Getz G, Domany E, Givol D. 2001. DNA microarrays identification of primary and secondary target genes regulated by p53. Oncogene 20:2225-2234. (Pubitemid 32531280)
16. Mazars P, Barboule N, Baldin V, Vidal S, Ducommun B, Valette A. 1995. Effects of TGF-beta 1 (transforming growth factor-beta 1) on the cell cycle regulation of human breast adenocarcinoma (MCF-7) cells. FEBS Lett 362:295-300.
17. Narayan G, Bourdon V, Chaganti S, Arias-Pulido H, Nandula SV, Rao PH, Gissmann L, Durst M, Schneider A, Pothuri B, Mansukhani M, Basso K, Chaganti RS, Murty VV. 2007. Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: Identification of candidate amplified and overexpressed genes. Genes Chromosomes Cancer 46:373-384. (Pubitemid 46411328)
18. Pfaffl MW. 2001. A new mathematical model for relative quantifi- cation in real-time RT-PCR. Nucleic Acids Res 29:e45.
19. Stoika RS, Yakymovych IA, Kashchak NI, Boyko MM, Korynevska AV, Klyuchyvska OY, Shafranska GI, Yakymovych MY, Zhylchuk VY, Kudryavets YY, Vorontsova AL. 2008. Effect of anticancer drugs on production of transforming growth factor and expression of p53 AND Bcl-2 proteins by MCF-7 and T47D cell lines of human breast carcinoma. Exp Oncol 30:35-41.
20. Wilson CA, Cajulis EE, Green JL, Olsen TM, Chung YA, Damore MA, Dering J, Calzone FJ, Slamon DJ. 2005. HER-2 overexpression differentially alters transforming growth factor-beta responses in luminal versus mesenchymal human breast cancer cells. Breast Cancer Res 7:R1058-R1079.
21. Yokoyama M, Nishi Y, Yoshii J, Okubo K, Matsubara K. 1996. Identification and cloning of neuroblastoma-specific and nerve tissue-specific genes through compiled expression profiles. DNA Res 3:311-320. (Pubitemid 126682777)