Peripheral polyneuropathy and bilateral optic neuropathy during treatment of chronic hepatitis C;Periphere polyneuropathie und beidseitige optikusneuropathie unter behandlung einer chronischen hepatitis C

Deutsche Medizinische Wochenschrift

Volumn 134, Issue 18, 2009, Pages 927-930

  Chrissafidou, A ^a   Musch E ^a  

^a Abteilung fur Innere Medizin   (Germany)

Author keywords

Hepatitis C; Interferon ; Optic neuropathy; Pegylated interferon ; Peripheral neuropathy

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA2A INTERFERON; AMANTADINE; CORTICOSTEROID; PEGINTERFERON ALPHA2A; RIBAVIRIN; VIRUS RNA; ANTIVIRUS AGENT; MACROGOL DERIVATIVE; PEGINTERFERON ALFA-2A;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CASE REPORT; DISEASE COURSE; DRUG MEGADOSE; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; LABORATORY TEST; LIVER STRUCTURE; OPTIC NERVE DISEASE; OUTCOME ASSESSMENT; PAPILLEDEMA; PERIPHERAL NEUROPATHY; PHYSICAL EXAMINATION; TREATMENT DURATION; ULTRASOUND; CHEMICALLY INDUCED DISORDER; DRUG COMBINATION; MIDDLE AGED; TREATMENT OUTCOME; VISUAL DISORDER;

ADRENAL CORTEX HORMONES; AMANTADINE; ANTIVIRAL AGENTS; DRUG THERAPY, COMBINATION; FEMALE; HEPATITIS C, CHRONIC; HUMANS; INTERFERON ALFA-2A; MIDDLE AGED; OPTIC NERVE DISEASES; PAPILLEDEMA; PERIPHERAL NERVOUS SYSTEM DISEASES; POLYETHYLENE GLYCOLS; RIBAVIRIN; TREATMENT OUTCOME; VISION DISORDERS;

EID: 65349084303     PISSN: 00120472     EISSN: 14394413     Source Type: Journal    
DOI: 10.1055/s-0029-1220250     Document Type: Article

References (26)

1. Briani C, Chemello L, Zara G et al. Peripheral neurotoxicity of pegylated interferon alpha: a prospective study in patient with HCV. Neurology 2006; 67: 781-785
2. Chan JW. Bilateral non-arteritic ischemic optic neuropathy associated with pegylated interferon for chronic hepatitis C. Eye 2007; 21: 877-878
3. Emir S, Kutluk R, Chan KW, Yalcin B, Varli K, Buyukpamukcu M. Peripheral neuropathy during alpha-interferon therapy in a child with Hodgkins' disease. Pediatr Hematol Oncol 1999; 16: 557-560
4. Foroozan R. Unilateral optic disc swelling and anemia associated with interferon alpha treatment. J Neuroophthalmol 2004; 24: 98- 99
5. Gabler B, Kroher G, Bogenreider T, Spiegel D, Preuner J, Lohman CP. Severe bilateral vision loss in malignant melanoma of the skin. Anterior ischemic optic neuropathy with irreversible vision and visual field loss in adjuvant interferon alfa-2b therapy. Ophthalmologe 2001; 98:672-673
6. Gupta R, Sing S, Tang R, Blackwell TA, Schiffman JS. Anterior ischemic optic neuropathy caused by interferon alpha therapy. Am J Med 2002;112:683-684
7. Kawano T, Shigehira M, Uto H et al. Retinal complications during interferon therapy for chronic hepatitis C. Am J Gastroenterol 1996; 91:309-313
8. Khiani V, Kelly T, Shibli A, Jensen D, Mohanty SR. Acute inflammatory demyelinating polyneuropathy associated with pegylated interferon α2a therapy for chronic hepatitis C virus infection. World J Gastroenterol 2008; 14:318-321
9. Kirchhoff A, Kirchhoff U, Lafrenz M, Guthoff R. Beidseitige AION nach einer Kombinationstherapie mit PEG-Interferon Alpha-2b und Ribavirin bei Hepatitis C. Klin Monatsbl Augenheilkd 2004; 221: 791- 793
10. Koskinas J, Kilidireas C, Karandreas N et al. Severe hepatitis C virus- related cryoglobulinaemic sensory-motor polyneuropathy treated with pegylated interferon-a2b and ribavirin: clinical, laboratory and neurophysiological study. Liver Int 2007; 27: 414-420
11. Lapinski TW, Nowacka B, Michalewicz M. The peripheral polyneuropathy in patients with chronic HCV infection treated with peginter- feron alfa with ribavirin. Pol Merkur Lekarski 2005; 18: 431-432
12. Lohmann CP, Kroher G, Bogenrieder T, Spiegel D, Preuner J. Severe loss of vision during adjuvant interferon alfa 2b treatment for malignant melanoma. Lancet 1999; 353: 1326
13. Marzo M, Tintore M, Fabregues 0, Montalban X, Codina A. Chronic inflammatory demyelinating polyneuropathy during treatment with interferon-alpha. J Neurol Neurosurg Psychiatry 1998; 65: 604-615
14. Meriggoli MN, Rowin J. Chronic inflammatory demyelinating polyneuropathy after treatment with interferon-alpha. Muscle Nerve 2000;23:433-435
15. Norcia F, Di Alessandra M, Prandini F, Redaelli C. Natural interferon therapy: optic nerve ischemic damage? Ophthalmologica 1999; 213: 339-340
16. Ockenfels M, Lisch W. Ocular complications of adjuvant interferon therapy for malignant melanoma: a review. Hautarzt 2003; 54: 144- 147
17. Purvin VA. Anterior ischemic optic neuropathy secondary to interferon alfa. Arch Ophthalmol 1995;113:1041-1044
18. Schulman JA, Liang C, Kooragayala LM, KingJ. Posterior segment complications in patients with hepatitis C treated with interferon and ribavirin. Ophthalmology 2003; 110: 437-442
19. Shulman LM, Minagar A, Sharma K, Weiner WJ. Amantadine-induced peripheral neuropathy. Neurology 1999; 53: 1862-1865
20. Sene D, Touitou V, Bodaghi B et al. Intraocular complications of IFN- alpha and ribarivin therapy in patients with chronic viral hepatitis C. World J Gastroenterol 2007; 13: 3137-3140
21. Taylor JL Grossberg SE. The effects of interferon alpha on the production and action of other cytokines. Semin Oncol 1998; 25 (Suppl): 23-29
22. Tellez-Zenteno JF, Negrete-Pulido 0, Nunez M, Estanol-Vidal B, Garcia- Ramos G. Peripheral neuropathy during a second cycle of treatment with high doses of interferon-alpha in a patient with hepatitis C, and a review of the literature. Rev Neurol 2002; 35: 644-646
23. Tembl JI, Ferrer JM, Sevilla MT, Lago A, Mayordomo F, Vilchez JJ. Neurologic complications associated with hepatitis C virus infection. Neurology 1999; 53: 861-864
24. Trebst C, Wedemeyer H, Manns MP, Tillmann H, Windhagen A. Treatment of hepatitis C virus-associated inflammatory polyneuropathy with pegylated interferon-alpha and ribavirin. Eur J Gastroenterol Hepatol 2007; 19: 91-92
25. Vardizer Y, Linhart Y, Loewenstein A, Garzozi H, Mazawi N, Kesler A. Interferon-alpha-associated bilateral simultaneous ischemic optic neuropathy. J Neuroophthalmol 2003; 23: 256-259
26. Vigani AG, Mecedo-de-Oliveira A, Pavan MH, Pedro MN, Goncales FL jr. Hepatitis C virus infection, cryoglobulinemia, and peripheral neuropathy: a case report. Braz J Med Biol Res 2005; 38: 1729-1734