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Volumn 60, Issue 6, 2008, Pages 957-965

Effect of selected antidepressant drugs on cytochrome P450 2B (CYP2B) in rat liver. An in vitro and in vivo study

Author keywords

Antidepressants; Chronic treatment; CYP2B; Enzyme induction; Enzyme inhibition; In vitro study; One day treatment; Rat liver microsomes

Indexed keywords

16 BETA HYDROXYTESTOSTERONE; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CLOMIPRAMINE; CYTOCHROME P450 2B; DESIPRAMINE; FLUOXETINE; IMIPRAMINE; MIRTAZAPINE; NEFAZODONE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TESTOSTERONE DERIVATIVE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; CYTOCHROME P450 2B1;

EID: 65249185691     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (19)

References (65)
  • 1
    • 0032826802 scopus 로고
    • Distribution of mirtazapine (Remeron) in thirteen postmortem cases
    • Anderson DT, Fritz KL, Muto JJ: Distribution of mirtazapine (Remeron) in thirteen postmortem cases. J Anal Toxicol 1993, 23, 544-548.
    • (1993) J Anal Toxicol , vol.23 , pp. 544-548
    • Anderson, D.T.1    Fritz, K.L.2    Muto, J.J.3
  • 2
    • 0034973607 scopus 로고    scopus 로고
    • Cytochromes P450 and metabolism of xenobiotics
    • Anzenbacher P, Anzenbacherová E: Cytochromes P450 and metabolism of xenobiotics. Cell Mol Life Sci, 2001, 58, 737-747.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 737-747
    • Anzenbacher, P.1    Anzenbacherová, E.2
  • 3
    • 0026324283 scopus 로고
    • Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function
    • Ed. Waterman MR, Johnson EF, Academic Press Inc, Harcourt Brace Jovanovich, Publishers, San Diego, California, USA
    • Arlotto MP, Trant JM, Estabrook RW: Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function. In: Methods in Enzymology. Ed. Waterman MR, Johnson EF, Academic Press Inc., Harcourt Brace Jovanovich, Publishers, San Diego, California, USA, 1991, 206, 454-462.
    • (1991) Methods in Enzymology , vol.206 , pp. 454-462
    • Arlotto, M.P.1    Trant, J.M.2    Estabrook, R.W.3
  • 4
    • 0029940102 scopus 로고    scopus 로고
    • Pharmacology and pharmacokinetics of citalopram and other SSRIs
    • Baumann P: Pharmacology and pharmacokinetics of citalopram and other SSRIs. Int Clin Psychopharmacol, 1996, 11, 5-11.
    • (1996) Int Clin Psychopharmacol , vol.11 , pp. 5-11
    • Baumann, P.1
  • 5
    • 0025268525 scopus 로고
    • Influence of dose and route of administration on the kinetics of fluoxetine and its metabolite norfluoxetine in the rat
    • Caccia S, Cappi M, Fracasso C, Garattini S: Influence of dose and route of administration on the kinetics of fluoxetine and its metabolite norfluoxetine in the rat. Psychopharmacology (Berl), 1990, 100, 509-514.
    • (1990) Psychopharmacology (Berl) , vol.100 , pp. 509-514
    • Caccia, S.1    Cappi, M.2    Fracasso, C.3    Garattini, S.4
  • 6
    • 0028357551 scopus 로고
    • Plasma and brain pharmacokinetics of amitriptyline and its demethylated and hydroxylated metabolites after acute intraperitoneal injection in mice
    • Coudore F, Fialip J, Eschalier A, Lavarenne J: Plasma and brain pharmacokinetics of amitriptyline and its demethylated and hydroxylated metabolites after acute intraperitoneal injection in mice. Eur J Drug Metab Pharmacokinet, 1994, 19, 5-13.
    • (1994) Eur J Drug Metab Pharmacokinet , vol.19 , pp. 5-13
    • Coudore, F.1    Fialip, J.2    Eschalier, A.3    Lavarenne, J.4
  • 7
    • 0037307139 scopus 로고    scopus 로고
    • Mechanisms of cellular distribution of psychotropic drugs. Significance for drug action and interactions
    • Daniel WA: Mechanisms of cellular distribution of psychotropic drugs. Significance for drug action and interactions. Prog Neuropsychopharmacol Biol Psychiatry, 2003, 27, 65-73.
    • (2003) Prog Neuropsychopharmacol Biol Psychiatry , vol.27 , pp. 65-73
    • Daniel, W.A.1
  • 8
    • 33645670098 scopus 로고    scopus 로고
    • The influence of long-term treatment with psychotropic drugs on cytochrome P450: The involvement of different mechanisms. Expert Opin Drug Metab
    • Daniel WA: The influence of long-term treatment with psychotropic drugs on cytochrome P450: the involvement of different mechanisms. Expert Opin Drug Metab Toxicol, 2005, 1, 203-217.
    • (2005) Toxicol , vol.1 , pp. 203-217
    • Daniel, W.A.1
  • 10
    • 33750807067 scopus 로고    scopus 로고
    • Direct and indirect interactions between antidepressant drugs and CYP2C6 in the rat liver during long-term treatment
    • Daniel WA, Haduch A, Syrek M, Boksa J: Direct and indirect interactions between antidepressant drugs and CYP2C6 in the rat liver during long-term treatment. Eur Neuropsychopharmacol, 2006, 16, 580-587.
    • (2006) Eur Neuropsychopharmacol , vol.16 , pp. 580-587
    • Daniel, W.A.1    Haduch, A.2    Syrek, M.3    Boksa, J.4
  • 11
    • 0036847924 scopus 로고    scopus 로고
    • Inhibition and possible induction of rat CYP2D after short- and long-term treatment with antidepressants
    • Daniel WA, Haduch A, Wójcikowski J: Inhibition and possible induction of rat CYP2D after short- and long-term treatment with antidepressants. J Pharm Pharmacol, 2002, 54, 1545-1552.
    • (2002) J Pharm Pharmacol , vol.54 , pp. 1545-1552
    • Daniel, W.A.1    Haduch, A.2    Wójcikowski, J.3
  • 12
    • 0029062586 scopus 로고
    • The pharmacokinetics of promazine and its metabolites after acute and chronic administration to rats - a comparison with the pharmacokinetics of imipramine
    • Daniel W, Syrek M, Janczar L, Boksa J: The pharmacokinetics of promazine and its metabolites after acute and chronic administration to rats - a comparison with the pharmacokinetics of imipramine. Pol J Pharmacol, 1995, 47, 127-136.
    • (1995) Pol J Pharmacol , vol.47 , pp. 127-136
    • Daniel, W.1    Syrek, M.2    Janczar, L.3    Boksa, J.4
  • 13
    • 0031047587 scopus 로고    scopus 로고
    • Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugs
    • Daniel WA, Wójcikowski J: Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugs. Pharmacol Toxicol, 1997, 80, 62-68.
    • (1997) Pharmacol Toxicol , vol.80 , pp. 62-68
    • Daniel, W.A.1    Wójcikowski, J.2
  • 14
    • 0344004865 scopus 로고    scopus 로고
    • The role of lysosomes in the cellular distribution of thioridazine and potential drug interactions
    • Daniel WA, Wójcikowski J: The role of lysosomes in the cellular distribution of thioridazine and potential drug interactions. Toxicol Appl Pharmacol, 1999, 158, 115-124.
    • (1999) Toxicol Appl Pharmacol , vol.158 , pp. 115-124
    • Daniel, W.A.1    Wójcikowski, J.2
  • 16
    • 0030601796 scopus 로고    scopus 로고
    • New protein in the rat CYP2B subfamily: Presence in liver microsomes of the constitutive CYP2B3 protein and the phenobarbital-inducible protein product of alternatively spliced CYP2B2 mRNA
    • Desrochers M, Christou M, Jefcoate C, Belzil A, Anderson A: New protein in the rat CYP2B subfamily: presence in liver microsomes of the constitutive CYP2B3 protein and the phenobarbital-inducible protein product of alternatively spliced CYP2B2 mRNA. Biochem Pharmacol, 1996, 52, 1311-1319.
    • (1996) Biochem Pharmacol , vol.52 , pp. 1311-1319
    • Desrochers, M.1    Christou, M.2    Jefcoate, C.3    Belzil, A.4    Anderson, A.5
  • 17
    • 0032811460 scopus 로고    scopus 로고
    • The role of CYP2B6 in human xenobiotic metabolism
    • Ekins S, Wrighton SA: The role of CYP2B6 in human xenobiotic metabolism. Drug Metab Rev, 1999, 31, 719-754.
    • (1999) Drug Metab Rev , vol.31 , pp. 719-754
    • Ekins, S.1    Wrighton, S.A.2
  • 18
    • 33646786799 scopus 로고    scopus 로고
    • Differential Regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor
    • Faucette SR, Sueyoshi R, Smith CM, Negishi M, LeCluyse EL, Wang H: Differential Regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor. J Pharmacol Exp Ther, 2006, 317, 1200-1209.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 1200-1209
    • Faucette, S.R.1    Sueyoshi, R.2    Smith, C.M.3    Negishi, M.4    LeCluyse, E.L.5    Wang, H.6
  • 21
    • 0027976519 scopus 로고
    • Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs
    • Ghersi-Egea JF, Leninger-Muller B, Suleman G, Siest G, Minn A: Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs. J Neurochem, 1994, 62, 1089-1096.
    • (1994) J Neurochem , vol.62 , pp. 1089-1096
    • Ghersi-Egea, J.F.1    Leninger-Muller, B.2    Suleman, G.3    Siest, G.4    Minn, A.5
  • 22
    • 0030966935 scopus 로고    scopus 로고
    • Cytochrome P450 isoenzymes activities in cultured rat and mouse liver slices
    • Gokhale MS, Bunton TE, Zurlo J, Yager JD: Cytochrome P450 isoenzymes activities in cultured rat and mouse liver slices. Xenobiotica, 1997, 27, 341-355.
    • (1997) Xenobiotica , vol.27 , pp. 341-355
    • Gokhale, M.S.1    Bunton, T.E.2    Zurlo, J.3    Yager, J.D.4
  • 23
    • 0027987792 scopus 로고
    • Pharmacokinetic optimization of therapy with newer antidepressants
    • Goodnick PJ: Pharmacokinetic optimization of therapy with newer antidepressants. Clin Pharmacokinet, 1994, 27, 307-330.
    • (1994) Clin Pharmacokinet , vol.27 , pp. 307-330
    • Goodnick, P.J.1
  • 24
    • 0030735150 scopus 로고    scopus 로고
    • Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species
    • Guengerich FP: Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species. Chem Biol Interact, 1997, 106, 161-182.
    • (1997) Chem Biol Interact , vol.106 , pp. 161-182
    • Guengerich, F.P.1
  • 26
    • 56149120059 scopus 로고    scopus 로고
    • The activity of cytochrome P450 CYP2B in rat liver during neuroleptic treatment
    • Haduch A, Wójcikowski J, Daniel WA: The activity of cytochrome P450 CYP2B in rat liver during neuroleptic treatment. Pharmacol Rep, 2007, 59, 606-612.
    • (2007) Pharmacol Rep , vol.59 , pp. 606-612
    • Haduch, A.1    Wójcikowski, J.2    Daniel, W.A.3
  • 27
    • 33644825809 scopus 로고    scopus 로고
    • The effect of tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs) and newer antidepressant drugs on the activity and level of rat CYP3A
    • Haduch A, Wójcikowski J, Daniel WA: The effect of tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs) and newer antidepressant drugs on the activity and level of rat CYP3A. Eur Neuropsychopharmacol, 2006, 16, 178-186.
    • (2006) Eur Neuropsychopharmacol , vol.16 , pp. 178-186
    • Haduch, A.1    Wójcikowski, J.2    Daniel, W.A.3
  • 28
    • 0034177265 scopus 로고    scopus 로고
    • Expression of human cytochrome P450 2B6 in Escherichia coli: Characterization of catalytic activity and expression levels in human liver
    • Hanna IH, Reed JR, Guengerich FP, Hollenberg PF: Expression of human cytochrome P450 2B6 in Escherichia coli: characterization of catalytic activity and expression levels in human liver. Arch Biochem Biophys, 2000, 376, 206-216.
    • (2000) Arch Biochem Biophys , vol.376 , pp. 206-216
    • Hanna, I.H.1    Reed, J.R.2    Guengerich, F.P.3    Hollenberg, P.F.4
  • 29
    • 0029833258 scopus 로고    scopus 로고
    • Catalytic role of cytochrome P450 2B6 in the N-demethylation of S-mephenytoin
    • Heyn H, White RB, Stevens JC: Catalytic role of cytochrome P450 2B6 in the N-demethylation of S-mephenytoin. Drug Metab Dispos, 1996, 24, 948-954.
    • (1996) Drug Metab Dispos , vol.24 , pp. 948-954
    • Heyn, H.1    White, R.B.2    Stevens, J.C.3
  • 30
    • 0032917167 scopus 로고    scopus 로고
    • Mirtazapine. A review of its use in major depression
    • Holm KJ, Markham A: Mirtazapine. A review of its use in major depression. Drugs, 1999, 57, 607-631.
    • (1999) Drugs , vol.57 , pp. 607-631
    • Holm, K.J.1    Markham, A.2
  • 31
    • 0034655747 scopus 로고    scopus 로고
    • Regulation of cytochrome P450 (CYP) genes by nuclear receptors
    • Honkakoski P, Negishi M: Regulation of cytochrome P450 (CYP) genes by nuclear receptors. Biochem J, 2000, 347, 321-337.
    • (2000) Biochem J , vol.347 , pp. 321-337
    • Honkakoski, P.1    Negishi, M.2
  • 32
    • 0031682988 scopus 로고    scopus 로고
    • The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene
    • Honkakoski P, Zelko I, Sueyoshi T, Negishi M: The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene. Mol Cell Biol, 1998, 18, 5652-5658.
    • (1998) Mol Cell Biol , vol.18 , pp. 5652-5658
    • Honkakoski, P.1    Zelko, I.2    Sueyoshi, T.3    Negishi, M.4
  • 33
    • 0029971798 scopus 로고    scopus 로고
    • Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat
    • Imaoka S, Yamada T, Hiroi T, Hayashi K, Sakaki T, Yabusaki Y, Funae Y: Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat. Biochem Pharmacol, 1996, 51, 1041-1050.
    • (1996) Biochem Pharmacol , vol.51 , pp. 1041-1050
    • Imaoka, S.1    Yamada, T.2    Hiroi, T.3    Hayashi, K.4    Sakaki, T.5    Yabusaki, Y.6    Funae, Y.7
  • 34
    • 34948880147 scopus 로고    scopus 로고
    • Differences in the expression and inducibility of cytochrome P450 2B isoenzymes in cultured rat brain neuronal and glial cells
    • Kapoor N, Pant AB, Dhawan A, Dwiewedi UN, Seth PK, Parmar D: Differences in the expression and inducibility of cytochrome P450 2B isoenzymes in cultured rat brain neuronal and glial cells. Mol Cell Biochem, 2007, 305, 199-207.
    • (2007) Mol Cell Biochem , vol.305 , pp. 199-207
    • Kapoor, N.1    Pant, A.B.2    Dhawan, A.3    Dwiewedi, U.N.4    Seth, P.K.5    Parmar, D.6
  • 35
    • 0033652116 scopus 로고    scopus 로고
    • Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene
    • Kawamoto T, Kakizaki S, Yoshinari K, Negishi M: Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene. Mol Endocrinol, 2000, 14, 1897-1905.
    • (2000) Mol Endocrinol , vol.14 , pp. 1897-1905
    • Kawamoto, T.1    Kakizaki, S.2    Yoshinari, K.3    Negishi, M.4
  • 36
    • 0032766430 scopus 로고    scopus 로고
    • Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene
    • Kawamoto T, Sueyoshi T, Zelko I, Moore R, Washburn K, Negishi M: Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene. Mol Cell Biol, 1999, 19, 6318-6322.
    • (1999) Mol Cell Biol , vol.19 , pp. 6318-6322
    • Kawamoto, T.1    Sueyoshi, T.2    Zelko, I.3    Moore, R.4    Washburn, K.5    Negishi, M.6
  • 37
    • 33746060489 scopus 로고    scopus 로고
    • Phenobarbital increases monkey in vivo nicotine disposition and induces liver and brain CYP2B6 protein
    • Lee AM, Miksys S, Tyndale RF: Phenobarbital increases monkey in vivo nicotine disposition and induces liver and brain CYP2B6 protein. Br J Pharmacol, 2006, 148, 786-794.
    • (2006) Br J Pharmacol , vol.148 , pp. 786-794
    • Lee, A.M.1    Miksys, S.2    Tyndale, R.F.3
  • 38
    • 0030963222 scopus 로고    scopus 로고
    • Molecular modeling of mammalian CYP2B isoforms and their interactions with substrates, inhibitors and redox partners
    • Lewis DFV, Lake BG: Molecular modeling of mammalian CYP2B isoforms and their interactions with substrates, inhibitors and redox partners. Xenobiotica, 1997, 27, 443-478.
    • (1997) Xenobiotica , vol.27 , pp. 443-478
    • Lewis, D.F.V.1    Lake, B.G.2
  • 39
    • 0034017040 scopus 로고    scopus 로고
    • Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment
    • Miksys S, Hoffman E, Tyndale RF: Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment. Biochem Pharmacol, 2000, 59, 1501-1511.
    • (2000) Biochem Pharmacol , vol.59 , pp. 1501-1511
    • Miksys, S.1    Hoffman, E.2    Tyndale, R.F.3
  • 40
    • 0038119910 scopus 로고    scopus 로고
    • Smoking, alcoholism and genetic polymorphism alter CYP2B6 levels in human brain
    • Miksys S, Lerman C, Shields PG, Mash DC, Tyndale RF: Smoking, alcoholism and genetic polymorphism alter CYP2B6 levels in human brain. Neuropharmacology, 2003, 45, 122-132.
    • (2003) Neuropharmacology , vol.45 , pp. 122-132
    • Miksys, S.1    Lerman, C.2    Shields, P.G.3    Mash, D.C.4    Tyndale, R.F.5
  • 41
    • 58149475254 scopus 로고    scopus 로고
    • Brain drug-metabolizing cytochrome P450 enzymes are active on vivo, demonstrated by mechanism-based enzyme inhibition
    • doi: 10.1038/npp.2008.110
    • Miksys S, Tyndale RF: Brain drug-metabolizing cytochrome P450 enzymes are active on vivo, demonstrated by mechanism-based enzyme inhibition. Neuropsychopharmacology, 2008, doi: 10.1038/npp.2008.110.
    • (2008) Neuropsychopharmacology
    • Miksys, S.1    Tyndale, R.F.2
  • 42
    • 33750296572 scopus 로고    scopus 로고
    • Nicotine induces brain CYP enzymes: Relevance to Parkinson's disease
    • Miksys S, Tyndale RF: Nicotine induces brain CYP enzymes: relevance to Parkinson's disease. J Neural Transm (Suppl), 2006, 70, 177-180.
    • (2006) J Neural Transm (Suppl) , vol.70 , pp. 177-180
    • Miksys, S.1    Tyndale, R.F.2
  • 44
    • 0031948975 scopus 로고    scopus 로고
    • Sex-dependent metabolism of xenobiotics
    • Mugford CA, Kedderis GL: Sex-dependent metabolism of xenobiotics. Drug Metab Rev, 1998, 30, 441-498.
    • (1998) Drug Metab Rev , vol.30 , pp. 441-498
    • Mugford, C.A.1    Kedderis, G.L.2
  • 45
    • 0025870577 scopus 로고
    • Difference in the susceptibility of two phenobarbital-inducible forms, P450IIB1 and P450IIB2, to thyroid hormone-and growth hormone-induced suppression in rat liver: Phenobarbital-inducible P450IIB2 suppression by thyroid hormone acting directly, but not through the pituitary system
    • Murayama N, Shimada M, Yamazoe Y, Kato R: Difference in the susceptibility of two phenobarbital-inducible forms, P450IIB1 and P450IIB2, to thyroid hormone-and growth hormone-induced suppression in rat liver: phenobarbital-inducible P450IIB2 suppression by thyroid hormone acting directly, but not through the pituitary system. Mol Pharmacol, 1991, 39, 811-817.
    • (1991) Mol Pharmacol , vol.39 , pp. 811-817
    • Murayama, N.1    Shimada, M.2    Yamazoe, Y.3    Kato, R.4
  • 46
    • 0026709837 scopus 로고
    • Inhibition and induction of cytochrome P450 2B1 in rat liver by promazine and chlorpromazine
    • Murray M: Inhibition and induction of cytochrome P450 2B1 in rat liver by promazine and chlorpromazine. Biochem Pharmacol, 1992, 44, 1219-1222.
    • (1992) Biochem Pharmacol , vol.44 , pp. 1219-1222
    • Murray, M.1
  • 47
    • 0030605954 scopus 로고    scopus 로고
    • Differential effects of neuroleptic agents on hepatic cytochrome P-450 isoenzymes in the male rat
    • Rane A, Liu Z, Levol R, Bjelfman C, Thys C, Ericson H, Hansson T et al.: Differential effects of neuroleptic agents on hepatic cytochrome P-450 isoenzymes in the male rat. Biochim Biophys Acta, 1996, 1291, 60-66.
    • (1996) Biochim Biophys Acta , vol.1291 , pp. 60-66
    • Rane, A.1    Liu, Z.2    Levol, R.3    Bjelfman, C.4    Thys, C.5    Ericson, H.6    Hansson, T.7
  • 48
    • 0030834058 scopus 로고    scopus 로고
    • Human cytochrome P450 enzymes: A status report summarizing their reactions, substrates, inducers, and inhibitors
    • Rendic S, Di Carlo F: Human cytochrome P450 enzymes: A status report summarizing their reactions, substrates, inducers, and inhibitors. Drug Metab Rev, 1997, 29, 413-580.
    • (1997) Drug Metab Rev , vol.29 , pp. 413-580
    • Rendic, S.1    Di Carlo, F.2
  • 49
    • 0025139447 scopus 로고
    • Purification and characterization of hepatic microsomal cytochrome P-450
    • Ryan DE, Levin W: Purification and characterization of hepatic microsomal cytochrome P-450 Pharmacol Ther, 1990, 45, 153-239.
    • (1990) Pharmacol Ther , vol.45 , pp. 153-239
    • Ryan, D.E.1    Levin, W.2
  • 50
    • 0032981063 scopus 로고    scopus 로고
    • Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding
    • Sanchez C, Hyttel J: Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding. Cell Mol Neurobiol, 1999, 19, 467-489.
    • (1999) Cell Mol Neurobiol , vol.19 , pp. 467-489
    • Sanchez, C.1    Hyttel, J.2
  • 51
    • 0027359523 scopus 로고
    • Regional distribution and expression modulation of cytochromeP-450 and epoxyde hydrolase mRNAs in the rat brain
    • Schilter B, Omiecinski CJ: Regional distribution and expression modulation of cytochromeP-450 and epoxyde hydrolase mRNAs in the rat brain. Mol Pharmacol, 1993, 44, 990-996.
    • (1993) Mol Pharmacol , vol.44 , pp. 990-996
    • Schilter, B.1    Omiecinski, C.J.2
  • 52
    • 0035501355 scopus 로고    scopus 로고
    • Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain
    • Schoedel KA, Sellers EM, Tyndale RF: Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain. Biochem Pharmacol, 2001, 62, 1025-1036.
    • (2001) Biochem Pharmacol , vol.62 , pp. 1025-1036
    • Schoedel, K.A.1    Sellers, E.M.2    Tyndale, R.F.3
  • 53
    • 33846809048 scopus 로고    scopus 로고
    • Neuroendocrinological mechanisms of actions of antidepressant drugs
    • Schüle C: Neuroendocrinological mechanisms of actions of antidepressant drugs. J Neuroendocrinol, 2006, 19, 213-226.
    • (2006) J Neuroendocrinol , vol.19 , pp. 213-226
    • Schüle, C.1
  • 57
    • 0031687643 scopus 로고    scopus 로고
    • Expression of multiple forms of cytochrome P450 and associated mono-oxygenase activities in rat brain regions
    • Tirumalai PS, Bhamre S, Upadhya SC, Boyd BR, Ravindranath V: Expression of multiple forms of cytochrome P450 and associated mono-oxygenase activities in rat brain regions. Biochem Pharmacol, 1998, 56, 371-375.
    • (1998) Biochem Pharmacol , vol.56 , pp. 371-375
    • Tirumalai, P.S.1    Bhamre, S.2    Upadhya, S.C.3    Boyd, B.R.4    Ravindranath, V.5
  • 58
    • 0024386144 scopus 로고
    • Metabolism and disposition of the 5-hydroxytryptamine uptake blocker sertraline on the rat and dog
    • Tremaine LM, Welch WM, Ronfeld RA: Metabolism and disposition of the 5-hydroxytryptamine uptake blocker sertraline on the rat and dog. Drug Metab Dispos, 1989, 17, 542-550.
    • (1989) Drug Metab Dispos , vol.17 , pp. 542-550
    • Tremaine, L.M.1    Welch, W.M.2    Ronfeld, R.A.3
  • 59
    • 0036509526 scopus 로고    scopus 로고
    • Toxicological consequences of differential regulation of cytochrome P450 isoforms in rat brain regions by phenobarbital
    • Upadhya SC, Chinta SJ, Pai HV, Boyd MR, Ravindranath V: Toxicological consequences of differential regulation of cytochrome P450 isoforms in rat brain regions by phenobarbital. Arch Biochem Biophys, 2002, 399, 56-65.
    • (2002) Arch Biochem Biophys , vol.399 , pp. 56-65
    • Upadhya, S.C.1    Chinta, S.J.2    Pai, H.V.3    Boyd, M.R.4    Ravindranath, V.5
  • 60
    • 0027464837 scopus 로고
    • Clinical pharmacokinetics of selective serotonin reuptake inhibitors
    • van Harten J: Clinical pharmacokinetics of selective serotonin reuptake inhibitors. Clin Pharmacokinet, 1993, 24, 203-220.
    • (1993) Clin Pharmacokinet , vol.24 , pp. 203-220
    • van Harten, J.1
  • 62
    • 0034509338 scopus 로고    scopus 로고
    • Distribution interactions between perazine and antidepressant drugs. In vivo studies
    • Wójcikowski J, Daniel WA: Distribution interactions between perazine and antidepressant drugs. In vivo studies. Pol J Pharmacol, 2000, 52, 449-457.
    • (2000) Pol J Pharmacol , vol.52 , pp. 449-457
    • Wójcikowski, J.1    Daniel, W.A.2
  • 63
    • 0036968060 scopus 로고    scopus 로고
    • Thioridazine - fluoxetine interaction at the level of the distribution process in vitro
    • Wójcikowski J, Daniel WA: Thioridazine - fluoxetine interaction at the level of the distribution process in vitro. Pol J Pharmacol, 2002, 54, 647-654.
    • (2002) Pol J Pharmacol , vol.54 , pp. 647-654
    • Wójcikowski, J.1    Daniel, W.A.2
  • 64
    • 45649083697 scopus 로고    scopus 로고
    • Regulation of liver cytochrome P450 by activation of brain dopaminergic system: Physiological and pharmacological implications
    • Wójcikowski J, Gołembiowska K, Daniel WA: Regulation of liver cytochrome P450 by activation of brain dopaminergic system: physiological and pharmacological implications. Biochem Pharmacol, 2008, 76, 258-267.
    • (2008) Biochem Pharmacol , vol.76 , pp. 258-267
    • Wójcikowski, J.1    Gołembiowska, K.2    Daniel, W.A.3
  • 65
    • 34547652315 scopus 로고    scopus 로고
    • The regulation of liver cytochrome P450 by the brain dopaminergic system
    • Wójcikowski J, Gołembiowska K, Daniel WA: The regulation of liver cytochrome P450 by the brain dopaminergic system. Curr Drug Metab, 2007, 8, 631-638.
    • (2007) Curr Drug Metab , vol.8 , pp. 631-638
    • Wójcikowski, J.1    Gołembiowska, K.2    Daniel, W.A.3


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