Effect of gastric pH-raising drugs on tebipenem pivoxil fine granules pharmacokinetics in healthy male volunteers

Japanese Journal of Chemotherapy

Volumn 57, Issue SUPPL. 1, 2009, Pages 99-102

  Nakashima, Mitsuyoshi ^a   Morita, Jun ^b   Aizawa, Kazumasa ^b  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b MEIJI SEIKA KAISHA LTD   (Japan)

Author keywords

Antacid; Drug interaction; Famotidine; Pharmacokinetics; Tebipenem pivoxil

Indexed keywords

ALUMINUM MAGNESIUM HYDROXIDE; FAMOTIDINE; TEBIPENEM PIVOXIL;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG EXCRETION; DRUG GRANULE; DRUG HALF LIFE; DRUG POTENCY; DRUG POTENTIATION; DRUG URINE LEVEL; HUMAN; HUMAN EXPERIMENT; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; SINGLE DRUG DOSE; STOMACH PH; VOLUNTEER;

EID: 65249178337     PISSN: 13407007     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Miyazaki S, Hosoyama T, Furuya N, Ishii Y, Matsumoto T, Ohno A, et al: In vitro and in vivo antibacterial activities of L-084, a novel oral carbapenem, against causative organisms of respiratory tract infections. Antimicrob Agents Chemother 2001; 45: 203-7
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5. 2-receptor antagonist, famotidine, on gastric secretion in healthy subjects. Clin Ther 1987; 9: 528-35