How well does blinding work in randomized controlled trials?: A counterpoint

Clinical Pharmacology and Therapeutics

Volumn 85, Issue 5, 2009, Pages 463-465

  Boehmer, J ^a   Yong, P ^b  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b BOSTON SCIENTIFIC CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL PRACTICE; CLINICAL RESEARCH; DOCTOR PATIENT RELATION; FOOD AND DRUG ADMINISTRATION; METHODOLOGY; OBSERVER BIAS; PATIENT ATTITUDE; PLACEBO EFFECT; PRACTICE GUIDELINE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SHORT SURVEY; TREATMENT OUTCOME; TREATMENT RESPONSE;

BIAS (EPIDEMIOLOGY); DOUBLE-BLIND METHOD; HUMANS; PATIENT SELECTION; PATIENTS; PLACEBO EFFECT; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH PERSONNEL; SINGLE-BLIND METHOD;

EID: 65249121379     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2009.32     Document Type: Short Survey

References (4)

1. Ney, P.G., Collins, C. & Spensor, C. Double blind: double talk or are there ways to do better research? Med. Hypotheses 21, 119-126 (1986).
2. Hhrobjartsson, A., Forfang, E., Haahr, M.T., Als-Nielsen, B. & Brorson, S. Blinded trials taken to the test: an analysis of randomized clinical trials that report tests for the success of blinding. Int. J. Epidemiol. 36, 654-663 (2007).
3. Moher, D., Schulz, K.F. & Altman, D. The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. JAMA 285, 1987-1991 (2001).
4. Bourge, R.C. et al. Randomized controlled trial of an implantable continuous hemodynamic monitor in patients with advanced heart failure: the COMPASS-HF Study. J. Am. Coll. Cardiol. 51, 1073-1079 (2008).