Transient outward potassium channel regulation in healthy and diabetic hearts

Canadian Journal of Physiology and Pharmacology

Volumn 87, Issue 2, 2009, Pages 77-83

  Gallego, Mónica ^a   Alday, Aintzane ^a   Urrutia, Janire ^a   Casis, Oscar ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Cardiomyopathy; Diabetes; Growth factors; Insulin; Sympathetic regulation; Transient outward potassium current

Indexed keywords

INSULIN; POTASSIUM CHANNEL;

CARDIOMYOPATHY; CONFERENCE PAPER; ELECTROCARDIOGRAM; HEART ARRHYTHMIA; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEART VENTRICLE FIBRILLATION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; SUDDEN DEAFNESS;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIAS, CARDIAC; DIABETES COMPLICATIONS; HUMANS; KINETICS; KV1.4 POTASSIUM CHANNEL; MYOCYTES, CARDIAC; POTASSIUM CHANNELS; SHAL POTASSIUM CHANNELS; SYMPATHETIC NERVOUS SYSTEM;

EID: 65249112149     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y08-106     Document Type: Conference Paper

References (48)

1. Benitah, J.P., Gómez, A.M., Bailly, P., Da-Ponte, J.P., Berson, G., Delgado, C., and Lorente, P. 1993. Heterogeneity of the early outward current in ventricular cells isolated from normal and hy- pertrophied rat hearts. J. Physiol. 469: 111-138. PMID:7505822.
2. Birnbaum, S.G., Varga, A.W., Yuan, L.L., Anderson, A.E., Sweatt, J.D., and Schrader, L.A. 2004. Structure and function of Kv4-family transient potassium channels. Physiol. Rev. 84: 803-833. doi:10.1152/physrev.00039. 2003. PMID:15269337.
3. Bitar, M.S., Koulu, M., Rapoport, S.I., and Linnoila, M. 1987. Adrenal catecholamine metabolism and myocardial adrenergic receptors in streptozotocin diabetic rats. Biochem. Pharmacol. 36: 1011-1016. doi:10.1016/0006- 2952(87)90407-2. PMID: 2882757.
4. 1B-adrenergic receptor to the phospholipase C pathway in Xenopus oocytes: the role of Go. J. Biol. Chem. 268: 7532-7537. PMID:8385110.
5. Brown, J.H., Buxton, I.L.O., and Brunton, L.L. 1985. α1-Adrenergic and muscarinic cholinergic stimulation of phosphoinositide hydrolysis in adult rat cardiomyocytes. Circ. Res. 57: 532-537. PMID:2412720.
6. Casis, O., and Echevarria, E. 2004. Diabetic cardiomyopathy: electromechanical cellular alterations. Curr. Vasc. Pharmacol. 2: 237-248. doi:10.2174/1570161043385655. PMID:15320822.
7. Casis, O., Gallego, M., Iriarte, M., and Sanchez-Chapula, J.A. 2000. Effects of diabetic cardiomyopathy on regional electrophysiologic characteristics of rat ventricle. Diabetologia, 43: 101-109. doi:10.1007/s001250050013. PMID:10672450.
8. Coulombe, A., Momtaz, A., Richer, P., Swyngedauw, B., and Cor-aboeuf, E. 1994. Reduction of calcium independent transient outward potassium current density in DOCA salt hypertrophied rat ventricular myocytes. Pflügers Arch. Eur. J. Phys. 427: 47-55. doi:10.1007/BF00585941.
9. Dourado, M.M., and Dreyer, S.E. 1994. Regulation of A-currents by cell-cell interactions and neurotrophic factors in developing chick parasympathetic neurons. J. Physiol. 474: 367-377. MID:7516973.
10. ss in cardiac ventricular myocytes from diabetic rats. Life Sci. 79: 883-889. doi:10.1016/j.lfs.2006.03.014. PMID:16616210.
11. Gallego, M., and Casis, O. 2001. Regulation of cardiac transient outward potassium current by norepinephrine in normal and diabetic rats. Diabetes Metab. Res. Rev. 17: 304-309. doi:10.1002/ dmrr.212. PMID:11544615.
12. Gallego, M., Casis, E., Izquierdo, M.J., and Casis, O. 2000. Restoration of cardiac transient outward potassium current by norepinephrine in diabetic rats. Pflugers Arch. 441: 102-107. doi:10.1007/s004240000374. PMID:11205047.
13. Gallego, M., Setien, R., Izquierdo, M.J., Casis, O., and Casis, E. 2003. Diabetes-induced biochemical changes in central and peripheral catecholaminergic systems. Physiol. Res. 52: 735-741. PMID:14640895.
14. + current via a cAMP/PKA-mediated pathway in the rat heart. Am. J. Physiol. Cell Physiol. 288: C577-C585. doi:10.1152/ajpcell.00124.2004. PMID:15496483.
15. Guo, W., Kamiya, K., and Toyama, J. 1995. bFGF promotes functional expressions of transient outward currents in cultured neonatal rat ventricular cells. Pflugers Arch.-. Eur. J. Phys. 430: 1015-1017. doi:10.1007/BF01837417.
16. Guo, W., Kamiya, K., and Toyama, J. 1996. Modulated expression of transient outward current in cultured neonatal rat ventricular myocytes: comparison with development in situ. Cardiovasc. Res. 32: 524-533. PMID:8881513.
17. + channel expression by myocardial hypertrophic factors in cultured newborn rat ventricular cells. J. Mol. Cell. Cardiol. 30: 1449-1455. doi:10.1006/jmcc. 1998.0730. PMID:9710812.
18. Han, W.P., Barr, S.C., Pacioretty, L.M., and Gilmour, R.F., Jr. 1997. Restoration of the transient outward potassium current by noradrenaline in chagasic canine epicardium. J. Physiol. 500: 75-83. PMID:9097934.
19. Horie, K., Itoh, H., and Tsujimoto, G. 1995. Hamster alpha 1B- adrenergic receptor directly activates Gs in the transfected Chinese hamster ovary cells. Mol. Pharmacol. 48: 392-400. PMID:7565618.
20. Kobayashi, K., Amemiya, S., Kobayashi, K., Sawanobori, E., Mo- chizuki, M., Ishihara, T., et al. 1999. The involvement of growth hormone-binding protein in altered GH-IGF axis in IDDM. En- docr. J. 46: S67-S69. doi:10.1507/endocrj.46.Suppl-S67. PMID:12054124.
21. Lengyel, C., Virag, L., Biro, T., Jost, R., Magyar, J., Bliczki, P., et al. 2007. Diabetes mellitus attenuates the repolarization reserve in mammalian heart. Cardiovasc. Res. 73: 512-520. doi:10. 1016/j.cardiores.2006.11. 010. PMID:17182020.
22. +-current in QT prolongation in the alloxan-induced diabetic rabbit heart. Acta Physiol. (Oxf.), 192: 359-368. doi:10.1111/j.1748-1716. 2007.01753.x. PMID:17970826.
23. Liu, Q.Y., Rosen, M.R., McKinnon, D., and Robinson, R.B. 1998. Sympathetic innervation modulates repolarizing K+ currents in rat epicardial myocytes. Am. J. Physiol. Heart Circ. Physiol. 274: H915-H922.
24. Magyar, J., Rusznak, Z., Szentesi, P., Szucs, G., and Kovacs, L. 1992. Action potentials and potassium currents in rat ventricular muscle during experimental diabetes. J. Mol. Cell. Cardiol. 24: 841-853. doi:10.1016/0022-2828(92)91098-P. PMID: 1433314.
25. Magyar, J., Cseresnyes, Z., Rusznak, Z., Sipos, I., Szucs, G., and Kovacs, L. 1995. Effects of insulin on potassium currents of rat ventricular myocytes in streptozotocin diabetes. Gen. Physiol. Biophys. 14: 191-201. PMID:8586253.
26. Nishiyama, A., Ishii, D.N., Backx, P.H., Pulford, B.E., Birks, B.R., and Tamkum, M.M. 2001. Altered K+ channel gene expression in diabetic rat ventricle: isoforma switching between Kv4.2 and Kv1.4. Am. J. Physiol. Heart Circ. Physiol. 281: H1800-H1807. PMID:11557574.
27. Nishizuka, Y. 1988. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature, 334: 661-665. doi:10.1038/334661a0. PMID:3045562.
28. Pacioretty, L.M., Cooper, B.J., and Gilmour, R.F., Jr. 1994. Reduction of the transient outward potassium current in canine X- linked muscular dystrophy. Circulation, 90: 1350-1356. PMID:8087945.
29. Pacioretty, L.M., Barr, S.C., Han, W.P., and Gilmour, R.F., Jr. 1995. Reduction of the transient outward potassium current in a canine model of Chagas' disease. Am. J. Physiol. Heart Circ. Physiol. 268: H1258-H1267.
30. to, phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms. J. Physiol. 569: 7-39. doi:10.1113/jphysiol.2005.086223. PMID: 15831535.
31. + channel genes expression in type I diabetic cardiomyopathy. Biochem. Biophys. Res. Commun. 283: 549-553. doi:10.1006/bbrc.2001. 4825. PMID:11341759.
32. Ravens, U., Wang, X.L., and Wettwer, E. 1989. Alpha adrenoceptor stimulation reduces outward currents in rat ventricular myocytes. J. Pharmacol. Exp. Ther. 250: 364-370. PMID:2545864.
33. Retnakaran, R., and Zinman, B. 2008. type 1 diabetes, hyperglycaemia, and the heart. Lancet, 371: 1790-1799. doi:10.1016/S0140- 6736(08)60767-9. PMID:18502304.
34. Robillon, J.F., Sadoul, J.L., Benmerabet, S., Joly-Lemoine, L., Fre- denrich, A., and Canivet, B. 1999. Assessment of cardiac arrhythmic risk in diabetic patients using QT dispersion abnormalities. Diabetes Metab. 25: 419-423. PMID:10592865.
35. Roden, D.M., Balser, J.R., George, A.L., Jr., and Anderson, M.E. 2002. Cardiac ion channels. Annu. Rev. Physiol. 64: 431-475. doi:10.1146/annurev.physiol.64.083101.145105. PMID:11826275.
36. Shimoni, Y., Severson, D., and Giles, W. 1995. Thyroid status and diabetes modulate regional differences in potassium currents in rat ventricle. J. Physiol. 488: 673-688. PMID:8576857.
37. Shimoni, Y., Fiset, C., Clark, R.B., Dixon, J.E., McKinnon, D., and Giles, W.R. 1997. Thyroid hormone regulates postnatal expression of transient K+ channel isoforms in rat ventricle. J. Physiol. 500: 65-73. PMID:9097933.
38. + cur-rents in rat heart: role of insulin. J. Physiol. 507: 485-496. doi:10.1111/j.1469- 7793.1998.485bt.x. PMID:9518707.
39. + currents depends on the integrity of the cytoskeleton. J. Physiol. 514: 735-745. doi:10.1111/j.1469-7793. 1999.735ad.x. PMID:9882746.
40. Steinberg, S.F., and Brunton, L.L. 2001. Compartmentation of G protein-coupled signaling pathways in cardiac myocytes. Annu. Rev. Pharmacol. Toxicol. 41: 751-773. doi:10.1146/annurev. pharmtox.41.1.751. PMID:11264475.
41. Tohse, N., Nayaka, H., Hattori, Y., Endou, M., and Kanno, M. 1990. Inhibitory effect mediated by alpha 1-adrenoceptors on transient outward current in isolated rat ventricular cells. Pflugers Arch. 415: 575-581. doi:10.1007/BF02583508. PMID: 2158067.
42. Tomlinson, K.C., Gardiner, S.M., Hebden, A., and Bennett, T. 1992. Functional consequences of streptozotocin-induced diabetes mellitus, with particular reference to the cardiovascular system. Pharmacol. Rev. 44: 103-150. PMID:1557425.
43. Van Der Heyden, M.A.G., Wijnhover, T.J.M., and Opthof, T. 2006. Molecular aspects of adrenergic modulation of the transient outward current. Cardiovasc. Res. 71: 430-442. doi:10.1016/j. cardiores.2006.04.012. PMID:16762331.
44. + channel gene expression in rat ventricle. J. Physiol. 504: 271-286. doi:10.1111/j.1469-7793.1997.271be. x. PMID:9365903.
45. to in rats after myocardial infarction. Am. J. Physiol. Heart Circ. Physiol. 278: H1105-H1116. PMID:10749704.
46. + current in ventricular myocytes from acromegalic rats. Am. J. Physiol. Heart Circ. Physiol. 260: H935-H942.
47. + current in ventricular myocytes from diabetic rats. Am. J. Physiol. Heart Circ. Physiol. 271: H2190-H2196.
48. Zhang, L., Parratt, J.R., Beastall, G.H., Pyne, N.J., and Furman, B.L. 2002. Streptozotocin diabetes protects against arrhythmias in rat isolated hearts: role of hypothyroidism. Eur. J. Pharmacol. 435: 269-276. doi:10.1016/S0014-2999(01)01398-X. PMID: 11821037.