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Volumn 13, Issue 4, 2009, Pages 341-343

How can we recognize "disease modification" effects?

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE VACCINE; BAPINEUZUMAB; BIOLOGICAL MARKER; LY 2062430; MONOCLONAL ANTIBODY; N2 [2 (3,5 DIFLUOROPHENYL) 2 HYDROXYACETYL] N1 (6,7 DIHYDRO 5 METHYL 6 OXO 5H DIBENZ[B,D]AZEPIN 7 YL)ALANINAMIDE; SOLANEZUMAB; UNCLASSIFIED DRUG;

EID: 65249111508     PISSN: 12797707     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12603-009-0036-7     Document Type: Article
Times cited : (23)

References (33)
  • 1
    • 65249111809 scopus 로고    scopus 로고
    • European Medicines Agency, Committee for Medicinal Products for Human Use. Guideline on medicinal products for the treatment of Alzheimer's disease and other dementias. Doc. Ref. CPMP/EWP/553/95 Rev. 1. London. 24 July 2008.
    • European Medicines Agency, Committee for Medicinal Products for Human Use. Guideline on medicinal products for the treatment of Alzheimer's disease and other dementias. Doc. Ref. CPMP/EWP/553/95 Rev. 1. London. 24 July 2008.
  • 2
    • 33744900086 scopus 로고    scopus 로고
    • Perspective: Optimal Design of Clinical Trials for Drugs Designed to Slow the Course of Alzheimer's Disease
    • Mobs RC, Kawas C, Carillio M: Perspective: Optimal Design of Clinical Trials for Drugs Designed to Slow the Course of Alzheimer's Disease. Alzheimer's and Dementia 2006;2:131-139.
    • (2006) Alzheimer's and Dementia , vol.2 , pp. 131-139
    • Mobs, R.C.1    Kawas, C.2    Carillio, M.3
  • 4
    • 33746551430 scopus 로고    scopus 로고
    • U.S. Department of Health and Human Services, Food and Drug Administration, Washington, DC, March
    • U.S. Department of Health and Human Services, Food and Drug Administration. Critical path opportunities report. Washington, DC, March 2006.
    • (2006) Critical path opportunities report
  • 5
    • 0033603814 scopus 로고    scopus 로고
    • Are Surrogate Markers Adequate to Assess Cardiovascular Disease Drugs?
    • Temple R. Are Surrogate Markers Adequate to Assess Cardiovascular Disease Drugs? JAMA 1999;282:790-795.
    • (1999) JAMA , vol.282 , pp. 790-795
    • Temple, R.1
  • 6
    • 0037371280 scopus 로고    scopus 로고
    • Imaging based measures of disease progression in clinical trials of disease modifying drugs for Alzheimer disease
    • Matthews B, Siemers ER, Mozley PD. Imaging based measures of disease progression in clinical trials of disease modifying drugs for Alzheimer disease. Am J Geriatr Psychiatry 2003;11:146-159.
    • (2003) Am J Geriatr Psychiatry , vol.11 , pp. 146-159
    • Matthews, B.1    Siemers, E.R.2    Mozley, P.D.3
  • 8
    • 0037411512 scopus 로고    scopus 로고
    • Frank RA, Galasko D, Hampel H, Hardy J, de Leon MJ, Mehta PD, Rogers J, Siemers E, Trojanowski JQ. Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer disease. Neurobiol Aging 2003;24:521-536.
    • Frank RA, Galasko D, Hampel H, Hardy J, de Leon MJ, Mehta PD, Rogers J, Siemers E, Trojanowski JQ. Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer disease. Neurobiol Aging 2003;24:521-536.
  • 11
    • 0033061647 scopus 로고    scopus 로고
    • Andreasen N, Hesse C, Davidsson P, Minthon L, Wallin A, Winblad B, Vanderstichele H, Vanmechelen E, Blennow K. Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer's disease: differences between early- and late-onset Alzheimer's disease and stability during the course of disease. Arch Neurol 1999;56:673-680.
    • Andreasen N, Hesse C, Davidsson P, Minthon L, Wallin A, Winblad B, Vanderstichele H, Vanmechelen E, Blennow K. Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer's disease: differences between early- and late-onset Alzheimer's disease and stability during the course of disease. Arch Neurol 1999;56:673-680.
  • 13
    • 0023833603 scopus 로고
    • The NINCDS-ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease: A clinicopathologic study of 57 cases
    • Tierney MC, Fisher RH, Lewis AJ, et al. The NINCDS-ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease: a clinicopathologic study of 57 cases. Neurology 1988;38:359-364.
    • (1988) Neurology , vol.38 , pp. 359-364
    • Tierney, M.C.1    Fisher, R.H.2    Lewis, A.J.3
  • 14
    • 43649085939 scopus 로고    scopus 로고
    • Commentary on "A roadmap for the prevention of dementia: The inaugural Leon Thal Symposium". Alzheimers Dement
    • Siemers ER, Paul SM. Commentary on "A roadmap for the prevention of dementia: The inaugural Leon Thal Symposium". Alzheimers Dement 2008;4:171-173.
    • (2008) , vol.4 , pp. 171-173
    • Siemers, E.R.1    Paul, S.M.2
  • 17
    • 18144415471 scopus 로고    scopus 로고
    • Effects of A immunization (AN1792) on MRI measures of cerbral volume in Alzheimer disease
    • for the AN1792(QS-21)-201 Study Team
    • Fox NC, Black RS, Gilman S, Rossor MN, Griffith SG, Jenkins L, Koller M for the AN1792(QS-21)-201 Study Team. Effects of A immunization (AN1792) on MRI measures of cerbral volume in Alzheimer disease. Neurology 2005;64:1563-1572.
    • (2005) Neurology , vol.64 , pp. 1563-1572
    • Fox, N.C.1    Black, R.S.2    Gilman, S.3    Rossor, M.N.4    Griffith, S.G.5    Jenkins, L.6    Koller, M.7
  • 22
    • 65249183343 scopus 로고    scopus 로고
    • A turnover in human subjects
    • Bateman RJ. A turnover in human subjects. Alzheimer's and Dementia 2008;4(Suppl 2):T123.
    • (2008) Alzheimer's and Dementia , vol.4 , Issue.SUPPL. 2
    • Bateman, R.J.1
  • 26
    • 65249163018 scopus 로고    scopus 로고
    • Clinical trials of bapineuzumab, a beta-amyloid-targeted immunotherapy in patients with mild to moderate Alzheimer's disease
    • Grundman M, Black R. Clinical trials of bapineuzumab, a beta-amyloid-targeted immunotherapy in patients with mild to moderate Alzheimer's disease. Alzheimer's and Dementia 2008;4(Suppl 2):T166.
    • (2008) Alzheimer's and Dementia , vol.4 , Issue.SUPPL. 2
    • Grundman, M.1    Black, R.2
  • 27
    • 5644239087 scopus 로고    scopus 로고
    • Alzheimer disease: Mechanistic understanding predicts novel therapies
    • Selkoe DJ. Alzheimer disease: mechanistic understanding predicts novel therapies. Ann Intern Med 2004;140:627-638.
    • (2004) Ann Intern Med , vol.140 , pp. 627-638
    • Selkoe, D.J.1
  • 28
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J. Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002;297(5580):353-356.
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 31
    • 0004143423 scopus 로고
    • Guidelines for the clinical evaluation of anti-dementia drugs
    • Rockville, MD: US Food and Drug Administration
    • Leber P. Guidelines for the clinical evaluation of anti-dementia drugs. First Draft. Rockville, MD: US Food and Drug Administration, 1990.
    • (1990) First Draft
    • Leber, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.