An updated reviewoon the clinicopathologic aspects of arrhythmogenic right ventricular cardiomyopathy

American Journal of Forensic Medicine and Pathology

Volumn 30, Issue 1, 2009, Pages 78-83

  El Demellawy, Dina ^a,d   Nasr, Ahmed ^b   Aloawmi, Salem ^c  

^a NORTHERN ONTARIO SCHOOL OF MEDICINE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

^d THUNDER BAY REGIONAL HEALTH SCIENCES CENTRE   (Canada)

Author keywords

Adipositas cordis; Arrhythmia; Arrhythmogenic right; Arrhythmogenic right ventricular cardiomyopathy; Fatty heart; Myocarditis; Sudden death; Ventricular dysplasia; Viral heart disease

Indexed keywords

AUTOPSY; CLINICAL FEATURE; DIAGNOSTIC ACCURACY; FAMILY; FATTY HEART; FORENSIC PATHOLOGY; GROUPS BY AGE; HEART RIGHT VENTRICLE DYSPLASIA; HISTOPATHOLOGY; HUMAN; LIPID STORAGE; MEDICAL PRACTICE; MEDICOLEGAL ASPECT; PATHOGENESIS; REVIEW; SUDDEN DEATH; CLASSIFICATION; FIBROSIS; GENETICS; HEART ARRHYTHMIA; HEART BLOCK; HEART MUSCLE; HEART VENTRICLE; MUTATION; PATHOLOGY;

ARRHYTHMIAS, CARDIAC; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; DEATH, SUDDEN; FIBROSIS; FORENSIC PATHOLOGY; HEART BLOCK; HEART VENTRICLES; HUMANS; MUTATION; MYOCARDIUM;

EID: 65249105470     PISSN: 01957910     EISSN: None     Source Type: Journal    
DOI: 10.1097/PAF.0b013e318187379e     Document Type: Review

References (38)

1. Dalal D, Nasir K, Bomma C, et al. Arrhythmogenic right ventricular dysplasia. A United States experience. Circulation. 2005; 112:3823-3832.
2. Blomstrom-Lundqvist C, Sabel KG, Olsson SB. A long term follow up of 15 patients with arrhythmogenic right ventricular dysplasia. Br Heart J. 1987; 58:477-488.
3. Marcus FI, Fontaine GH, Frank R, et al. Long-term follow-up in patients with arrhythmogenic right ventricular disease. Eur Heart J. 1989; 10(suppl D): 68-73.
4. Thiene G, Nava A, Angelini AAnatomoclinical aspects of arrhythmogenic right ventricular cardiomyopathy. In: Baroldi G, Camerini F, Goodwin JF, Eds. Advances in Cardiomyopathies. Berlin, Germany: Springer Verlag; 1990:397-408.
5. Corrado D, Cristina Basso C, Gaetano Thiene G, et al. Spectrum of clinicopathologic manifestations of arrhythmogenic right ventricular cardiomyopathy/ dysplasia: a multicenter study. J Am Coll Cardiol. 1997; 30:1512-1520.
6. Thiene G, Angelini A, Basso C, et al. Novel heart disease requiring transplantation. Adv Clin Pathol. 1998; 2:65-73.
7. Li D, Ahmad F, Gardner MJ, et al. The locus of a novel gene responsible for arrhythmogenic right-ventricular dysplasia characterized by early onset and high penetrance maps to chromosome 10p12-p14. Am J Hum Genet. 2000; 66:148-156.
8. Richardson P, McKenna WJ, Bristow M, et al. Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the definition and classification of cardiomyopathies. Circulation. 1996; 93:841-842.
9. McKenna WJ, Thiene G, Nava A, et al. Diagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathy. Task force of the Working Group Myocardial and Pericardial Disease of the European Society of Cardiology and of the Scientific Council on Cardiomyopathies of the International Society and Federation of Cardiology. Br Heart J. 1994; 71:215-218.
10. El Demellawy D, Butany J. Arrhythmogenic right ventricular cardiomyopathy: a clinicopathological and immunohistochemical study of 18 cases. Pathol Res Prac. 2006; 202:795; Abstract O105.
11. D'Amati G, Leone O, di Gioia CR, et al. Arrhythmogenic right ventricular cardiomyopathy: clinicopathologic correlation based on a revised definition of pathologic patterns. Hum Pathol. 2001; 32:1078-1086.
12. El Demellawy D, Butany J. Arrhythmogenic right ventricular cardiomyopathy/ dysplasia. A clinicopathological review. Modern Pathology supplement 2006 . Paper presented at: United States and Canadian Academy of Pathologists meeting; 2006.
13. Burke AP, Farb A, Tashko G, et al. Arrhythmogenic right ventricular cardiomyopathy and fatty replacement of the right ventricular myocardium: are they different diseases? Circulation. 1998; 97:1571-1580.
14. Shirani J, Berezowski K, Roberts WC. Quantitative measurement of normal and excessive (cor adiposum) subepicardial adipose tissue, its clinical significance, and its effect on electrocardiographic QRS voltage. Am J Cardiol. 1995; 76:414-418.
15. Bassco C, Thiene G. Adipositas cordis, fatty infiltration of the right ventricle, and arrhythmogenic right ventricular cardiomyopathy. Just a matter of fat? Cardiovasc Pathol. 2005; 14:37-41.
16. Fontaliran F, Fontaine G, Fillette F, et al. Nosologic frontiers of arrhythmogenic dysplasia. Quantitative variations of normal adipose tissue of the right heart ventricle. Arch Mal Coeur Vaiss. 1991; 84:33-38.
17. Tabib A, Loire R, Chalabreysse L, et al. Circumstances of death and gross and microscopic observations in a series of 200 cases of sudden death associated with arrhythmogenic right ventricular cardiomyopathy and/or dysplasia. Circulation. 2003; 108:3000-3005.
18. Webb J, Kerr C, Huckell V, et al. Left ventricular abnormalities in arrhythmogenic right ventricular dysplasia. Am Heart J. 1986; 58:568-570.
19. Manyari DE, Klein GJ, Gulamhusein S, et al. Arrhythmogenic right ventricular dysplasia: a generalized cardiomyopathy? Circulation. 1983; 68:251-257.
20. Basso C, Thiene G, Corrado D, et al. Arrhythmogenic right ventricular cardiomyopathy. Dysplasia, dystrophy or myocarditis? Circulation. 1996; 94: 983-991.
21. Angelini A, Basso C, Nava A, et al. Endomyocardial biopsy in arrhythmogenic right ventricular cardiomyopathy. Am Heart J. 1996; 132:203-206.
22. Lobo FV, Silver MD, Butany J, et al. Left ventricular involvement in right ventricular dysplasia/cardiomyopathy. Can J Cardiol. 1999; 15:1239-1247.
23. Fauchier JP, Fauchier L, Babuty D, et al. Time-domain signal-averaged electrocardiogram in nonischemic ventricular tachycardia. Pacing Clin Electrophysiol. 1996; 19:231-244.
24. Rampazzo A, Nava A, Erne P, et al. A new locus for arrhythmogenic right ventricular cardiomyopathy (ARVD2) maps to chromosome 1q42-q43. Hum Mol Genet. 1995; 4:2151-2154.
25. Rampazzo A, Nava A, Miorin M, et al. ARVD4, a new locus for arrhythmogenic right ventricular cardiomyopathy, maps to chromosome 2 long arm. Genomics. 1997; 45:259-263.
26. Ahmad F, Li D, Karibe A, et al. Localization of a gene responsible for arrhythmogenic right ventricular dysplasia to chromosome 3p23. Circulation. 1998; 98:2791-2795.
27. Rampazzo A, Nava A, Danieli GA, et al. The gene for arrhythmogenic right ventricular cardiomyopathy maps to chromosome 14q23-q24. Hum Mol Genet. 1994; 6:959-962.
28. Falaschi A, Camerini F, Giacca M, et al. A new locus for arrhythmogenic right ventricular dysplasia on the long arm of chromosome 14. Genomics. 1996; 31:193-200.
29. Rampazzo A, Nava A, Malacrida S, et al. Mutation in human desmoplakin domain binding to plakoglobin causes a dominant form of arrhythmogenic right ventricular cardiomyopathy. Am J Hum Genet. 2002; 71:1200-1206.
30. Ahmad F. The molecular genetics of arrhythmogenic right ventricular dysplasia/ cardiomyopathy. Clin Invest Med. 2003; 26:167-178.
31. Tiso N, Stephan DA, Nava A, et al. . Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2). Hum Mol Genet. 2001; 10: 189-194.
32. Tabib A, Loire R. Etude anatomo-clinique de 100 cas d́hypoplasie du muscle ventriculaire droit (dont 89 morts subites inattendues). Parenté avec l'anomalie d' Uhl. Arch Mal Coeur. 1992; 85:1789-1795.
33. Corrado D, Basso C, Thiene G, et al. Arrhythmogenic right ventricular cardiomyopathy: current diagnostic and management strategies. Cardiol Rev. 2001; 9:259-265.
34. Bonny A, Fontaine G, Hidden-Lucet, et al. Role of inflammation in the mechanism of onset of ventricular tachycardia in arrhythmogenic right ventricular dysplasia. Abstract. Circulation. 2003; 108 (suppl IV-VI):1032.
35. Calabrese F, Basso C, Carturan E, et al. Arrhythmogenic right ventricular cardiomyopathy/dysplasia: is there a role for viruses? Cardiovasc Pathol. 2006; 15:11-17.
36. Bowles NE, Ni J, Marcus F, et al. The detection of cardiotropic viruses in the myocardium of patients with arrhythmogenic right ventricular dysplasia/ cardiomyopathy. J Am Coll Cardiol. 2002; 39:892-895.
37. Nagata M, Hiroe M, Ishiyama S, et al. Apoptotic cell death in arrhythmogenic right ventricular cardiomyopathy: a comparative study with idiopathic sustained ventricular tachycardia. Jpn Heart J. 2000; 41:733-741.
38. Colston JT, Chandrasekar B, Freeman GL. Expression of apoptosis-related proteins in experimental coxsackievirus myocarditis. Cardiovasc Res. 1998; 38:158-168.